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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:ambroxol
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Accession:CHEBI:135590 term browser browse the term
Synonyms:related_synonym: Formula=C13H18Br2N2O;   InChI=1S/C13H18Br2N2O/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10/h5-6,10-11,17-18H,1-4,7,16H2/t10-,11-;   InChIKey=JBDGDEWWOUBZPM-XYPYZODXSA-N;   SMILES=C(N[C@H]1CC[C@@H](CC1)O)C2=C(N)C(Br)=CC(=C2)Br;   ambroxils;   ambroxol HCl;   ambroxol hydrochloride;   lasolvan
 xref: CAS:18683-91-5;   Drug_Central:147
 xref_mesh: MESH:D000551


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ambroxol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of CCL2 mRNA] CTD PMID:21921364 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of COL1A1 mRNA] CTD PMID:21921364 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of COL3A1 mRNA] CTD PMID:21921364 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of MMP2 mRNA] CTD PMID:21921364 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Ambroxol inhibits the reaction [Paraquat results in increased activity of MPO protein] CTD PMID:21921364 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions EXP Ambroxol inhibits the reaction [Paraquat results in decreased expression of SFTPA1 protein] CTD PMID:16824340 NCBI chr16:18,716,019...18,719,404
Ensembl chr16:18,716,019...18,719,403
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of TGFB1 mRNA] CTD PMID:21921364 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of TIMP2 mRNA] CTD PMID:21921364 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Ambroxol affects the reaction [Paraquat results in increased expression of TNF mRNA] CTD PMID:21921364 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19781
    role 19726
      chemical role 19270
        base 17015
          Bronsted base 17014
            organic amino compound 17008
              aromatic amine 13681
                ambroxol 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19781
    subatomic particle 19779
      composite particle 19779
        hadron 19779
          baryon 19779
            nucleon 19779
              atomic nucleus 19779
                atom 19779
                  main group element atom 19669
                    main group molecular entity 19669
                      s-block molecular entity 19434
                        hydrogen molecular entity 19429
                          hydrides 18757
                            inorganic hydride 17455
                              pnictogen hydride 17431
                                nitrogen hydride 17278
                                  azane 17010
                                    ammonia 17009
                                      organic amino compound 17008
                                        aromatic amine 13681
                                          ambroxol 9
paths to the root