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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:carazolol
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Accession:CHEBI:135261 term browser browse the term
Synonyms:related_synonym: DL-Carazolol;   Formula=C18H22N2O2;   InChI=1S/C18H22N2O2/c1-12(2)19-10-13(21)11-22-17-9-5-8-16-18(17)14-6-3-4-7-15(14)20-16/h3-9,12-13,19-21H,10-11H2,1-2H3;   InChIKey=BQXQGZPYHWWCEB-UHFFFAOYSA-N;   SMILES=O(CC(CNC(C)C)O)C=1C=2C=3C(NC2C=CC1)=CC=CC3;   racemic carazolol
 xref: CAS:57775-29-8;   Drug_Central:487
 xref_mesh: MESH:C014382


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carazolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1a interleukin 1 alpha multiple interactions ISO carazolol promotes the reaction [[Particulate Matter co-treated with n-hexane] results in increased expression of IL1A mRNA] CTD PMID:30503853 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO carazolol results in decreased expression of IL1B mRNA CTD PMID:30503853 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO carazolol inhibits the reaction [[Particulate Matter co-treated with Methylene Chloride] results in increased expression of MMP1 mRNA] CTD PMID:30503853 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO carazolol inhibits the reaction [[Particulate Matter co-treated with Methylene Chloride] results in increased expression of PTGS2 mRNA] CTD PMID:30503853 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    chemical entity 19829
      atom 19829
        nonmetal atom 19767
          nitrogen atom 18955
            nitrogen molecular entity 18955
              organonitrogen compound 18804
                organonitrogen heterocyclic compound 18148
                  dibenzopyrrole 252
                    carbazoles 252
                      carazolol 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            organic molecule 19677
                              organic cyclic compound 19490
                                organic heterocyclic compound 18852
                                  organic heteropolycyclic compound 18295
                                    organic heterotricyclic compound 15649
                                      dibenzopyrrole 252
                                        carbazoles 252
                                          carazolol 4
paths to the root