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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:135207 term browser browse the term
Definition:A diarylmethane that is 2-chlorophenyl(phenyl)methane substituted on the methane carbon by a 2-(dimethylamino)ethyl group. Used in the treatment of dry cough, it suppresses the cough reflex by a direct effect on the cough centre in the medulla of the brain.
Synonyms:exact_synonym: 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol
 related_synonym: Formula=C17H20ClNO;   InChI=1S/C17H20ClNO/c1-19(2)13-12-17(20,14-8-4-3-5-9-14)15-10-6-7-11-16(15)18/h3-11,20H,12-13H2,1-2H3;   InChIKey=WRCHFMBCVFFYEQ-UHFFFAOYSA-N;   SMILES=C(CCN(C)C)(O)(C1=C(Cl)C=CC=C1)C2=CC=CC=C2;   chlophedianol;   clofedanolum
 xref: Beilstein:2813922;   CAS:791-35-5;   DrugBank:DB04837;   Drug_Central:585;   KEGG:D07721
 xref_mesh: MESH:C010432
 xref: PMID:14478530;   PMID:29438107;   Patent:CN101844989;   Reaxys:2813922;   Wikipedia:Clofedanol

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clofedanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO clofedanol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
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  CHEBI ontology 19810
    role 19758
      application 19420
        pharmaceutical 19293
          drug 19293
            antitussive 229
              clofedanol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    main group molecular entity 19696
                      s-block molecular entity 19456
                        hydrogen molecular entity 19447
                          hydrides 18703
                            inorganic hydride 17433
                              pnictogen hydride 17405
                                nitrogen hydride 17247
                                  azane 16964
                                    ammonia 16963
                                      organic amino compound 16962
                                        tertiary amino compound 8638
                                          clofedanol 1
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