Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:135207 term browser browse the term
Definition:A diarylmethane that is 2-chlorophenyl(phenyl)methane substituted on the methane carbon by a 2-(dimethylamino)ethyl group. Used in the treatment of dry cough, it suppresses the cough reflex by a direct effect on the cough centre in the medulla of the brain.
Synonyms:exact_synonym: 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol
 related_synonym: Formula=C17H20ClNO;   InChI=1S/C17H20ClNO/c1-19(2)13-12-17(20,14-8-4-3-5-9-14)15-10-6-7-11-16(15)18/h3-11,20H,12-13H2,1-2H3;   InChIKey=WRCHFMBCVFFYEQ-UHFFFAOYSA-N;   SMILES=C(CCN(C)C)(O)(C1=C(Cl)C=CC=C1)C2=CC=CC=C2;   chlophedianol;   clofedanolum
 xref: Beilstein:2813922 "ChemIDplus";   CAS:791-35-5 "ChemIDplus";   CAS:791-35-5 "DrugCentral";   DrugBank:DB04837;   Drug_Central:585 "DrugCentral";   KEGG:D07721
 xref_mesh: MESH:C010432
 xref: PMID:14478530 "Europe PMC";   PMID:29438107 "Europe PMC";   Patent:CN101844989;   Reaxys:2813922 "Reaxys";   Wikipedia:Clofedanol

show annotations for term's descendants       view all columns           Sort by:
clofedanol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            antitussive 226
              clofedanol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    main group molecular entity 19545
                      s-block molecular entity 19329
                        hydrogen molecular entity 19319
                          hydrides 18242
                            inorganic hydride 17104
                              pnictogen hydride 17062
                                nitrogen hydride 16885
                                  azane 16564
                                    ammonia 16561
                                      organic amino compound 16560
                                        tertiary amino compound 8521
                                          clofedanol 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.