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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:135154 term browser browse the term
Synonyms:related_synonym: Formula=C16H26N2O2;   InChI=1S/C16H26N2O2/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13/h7-10H,5-6,11-12,17H2,1-4H3;   InChIKey=OWQIUQKMMPDHQQ-UHFFFAOYSA-N;   SMILES=C(OCC(CN(CC)CC)(C)C)(=O)C1=CC=C(C=C1)N;   larocaine
 xref: CAS:94-15-5;   Drug_Central:3154
 xref_mesh: MESH:C066888

show annotations for term's descendants           Sort by:
dimethocaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D increases hydrolysis ISO CES1 protein results in increased hydrolysis of dimethocaine CTD PMID:25445008 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases hydroxylation ISO CYP1A2 protein results in increased hydroxylation of dimethocaine CTD PMID:24309420 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases hydroxylation ISO CYP2D6 protein results in increased hydroxylation of dimethocaine CTD PMID:24309420 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases hydroxylation
decreases ethylation
ISO CYP3A4 protein results in increased hydroxylation of dimethocaine
CYP3A4 protein results in decreased ethylation of dimethocaine
CTD PMID:24309420 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Nat2 N-acetyltransferase 2 increases acetylation ISO NAT2 protein results in increased acetylation of dimethocaine CTD PMID:24309420 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    chemical entity 19875
      group 19787
        inorganic group 19219
          oxo group 18468
            organic oxo compound 18468
              carbonyl compound 18468
                carboxylic ester 14383
                  benzoate ester 4325
                    dimethocaine 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19875
    subatomic particle 19873
      composite particle 19873
        hadron 19873
          baryon 19873
            nucleon 19873
              atomic nucleus 19873
                atom 19873
                  main group element atom 19763
                    p-block element atom 19763
                      carbon group element atom 19668
                        carbon atom 19657
                          organic molecular entity 19657
                            organic group 18569
                              organic divalent group 18560
                                organodiyl group 18560
                                  carbonyl group 18468
                                    carbonyl compound 18468
                                      carboxylic acid 18142
                                        aromatic carboxylic acid 10919
                                          benzoic acids 10888
                                            benzoate ester 4325
                                              dimethocaine 5
paths to the root