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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:bupranolol
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Accession:CHEBI:135123 term browser browse the term
Synonyms:related_synonym: Formula=C14H22ClNO2;   InChI=1S/C14H22ClNO2/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4/h5-7,11,16-17H,8-9H2,1-4H3;   InChIKey=HQIRNZOQPUAHHV-UHFFFAOYSA-N;   SMILES=O(CC(CNC(C)(C)C)O)C1=C(Cl)C=CC(=C1)C;   bupranol;   bupranolol HCl;   bupranolol hydrochloride
 xref: CAS:14556-46-8;   Drug_Central:433;   HMDB:HMDB0015697
 xref_mesh: MESH:D002046



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bupranolol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 multiple interactions
decreases activity
ISO [Bupranolol co-treated with ADRB1] results in increased abundance of Cyclic AMP; Bupranolol inhibits the reaction [[CGP 12177 binds to ADRB1 protein] which results in increased abundance of Cyclic AMP]
Bupranolol results in decreased activity of ADRB1 protein
CTD PMID:2565296 PMID:12761341 PMID:15060759 NCBI chr 1:255,772,217...255,773,617
Ensembl chr 1:255,771,597...255,807,259
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      group 19722
        polyatomic entity 19721
          molecule 19572
            organic molecule 19549
              organic cyclic compound 19343
                organic aromatic compound 19189
                  aromatic ether 16240
                    bupranolol 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    main group molecular entity 19698
                      p-block molecular entity 19698
                        carbon group molecular entity 19619
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organochalcogen compound 19052
                                organooxygen compound 18998
                                  ether 16923
                                    aromatic ether 16240
                                      bupranolol 1
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