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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:135105 term browser browse the term
Synonyms:related_synonym: BQ 22-708;   BQ 22708;   Formula=C14H15N5O;   InChI=1S/C14H15N5O/c15-16-13-8-11-9-19(7-6-12(11)17-18-13)14(20)10-4-2-1-3-5-10/h1-5,8H,6-7,9,15H2,(H,16,18);   InChIKey=ALAXZYHFVBSJKZ-UHFFFAOYSA-N;   SMILES=C(=O)(N1CC2=C(CC1)N=NC(=C2)NN)C3=CC=CC=C3;   endralazine mesilate;   endralazine mesylate;   miretilan
 xref: CAS:39715-02-1;   Drug_Central:1008
 xref_mesh: MESH:C014926

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endralazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ren renin increases activity EXP BQ 22-708 results in increased activity of REN protein CTD PMID:7018762 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      atom 19782
        nonmetal atom 19657
          nitrogen atom 18539
            nitrogen molecular entity 18539
              amide 17387
                aromatic amide 6676
                  arenecarboxamide 6507
                    benzamides 6507
                      endralazine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        carboacyl group 17346
                                          univalent carboacyl group 17346
                                            carbamoyl group 17132
                                              carboxamide 17132
                                                monocarboxylic acid amide 14551
                                                  arenecarboxamide 6507
                                                    benzamides 6507
                                                      endralazine 1
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.