Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:propacetamol
go back to main search page
Accession:CHEBI:135089 term browser browse the term
Synonyms:related_synonym: Formula=C14H20N2O3;   InChI=1S/C14H20N2O3/c1-4-16(5-2)10-14(18)19-13-8-6-12(7-9-13)15-11(3)17/h6-9H,4-5,10H2,1-3H3,(H,15,17);   InChIKey=QTGAJCQTLIRCFL-UHFFFAOYSA-N;   SMILES=O(C(CN(CC)CC)=O)C1=CC=C(C=C1)NC(C)=O;   proparacetamol
 xref: CAS:66532-85-2;   Drug_Central:2290
 xref_mesh: MESH:C063776


show annotations for term's descendants           Sort by:
 
propacetamol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO propacetamol results in increased expression of BAX protein
kaempferol inhibits the reaction [propacetamol results in increased expression of BAX protein]
CTD PMID:29574133 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO propacetamol results in increased cleavage of CASP3 protein
kaempferol inhibits the reaction [propacetamol results in increased cleavage of CASP3 protein]
CTD PMID:29574133 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase decreases activity
multiple interactions
ISO propacetamol results in decreased activity of CAT protein
kaempferol inhibits the reaction [propacetamol results in decreased activity of CAT protein]
CTD PMID:29574133 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression
multiple interactions
ISO propacetamol results in increased expression of CYP2E1 protein
kaempferol inhibits the reaction [propacetamol results in increased expression of CYP2E1 protein]
CTD PMID:29574133 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit affects expression
multiple interactions
ISO propacetamol affects the expression of GCLC protein
kaempferol affects the reaction [propacetamol affects the expression of GCLC protein]
CTD PMID:29574133 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
ISO kaempferol inhibits the reaction [propacetamol results in increased activity of GPT protein] CTD PMID:29574133 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Hmox1 heme oxygenase 1 affects expression
multiple interactions
ISO propacetamol affects the expression of HMOX1 protein
kaempferol affects the reaction [propacetamol affects the expression of HMOX1 protein]
CTD PMID:29574133 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO kaempferol inhibits the reaction [propacetamol results in increased expression of IL6 protein] CTD PMID:29574133 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO kaempferol inhibits the reaction [propacetamol results in increased phosphorylation of MAPK1 protein] CTD PMID:29574133 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO kaempferol inhibits the reaction [propacetamol results in increased phosphorylation of MAPK3 protein] CTD PMID:29574133 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects expression
multiple interactions
ISO propacetamol affects the expression of NFE2L2 protein
kaempferol affects the reaction [propacetamol affects the expression of NFE2L2 protein]
CTD PMID:29574133 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 increases expression
multiple interactions
ISO propacetamol results in increased expression of RIPK1 protein
kaempferol inhibits the reaction [propacetamol results in increased expression of RIPK1 protein]
CTD PMID:29574133 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO propacetamol results in increased expression of TNF protein
kaempferol inhibits the reaction [propacetamol results in increased expression of TNF protein]
CTD PMID:29574133 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases expression
multiple interactions
ISO propacetamol results in decreased expression of UGT1A1 protein
kaempferol inhibits the reaction [propacetamol results in decreased expression of UGT1A1 protein]
CTD PMID:29574133 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19817
    role 19767
      application 19445
        refrigerant 17479
          ammonia 17013
            organic amino compound 17012
              amino acid 14113
                alpha-amino acid 11599
                  alpha-amino acid ester 231
                    propacetamol 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19817
    subatomic particle 19815
      composite particle 19815
        hadron 19815
          baryon 19815
            nucleon 19815
              atomic nucleus 19815
                atom 19815
                  main group element atom 19705
                    p-block element atom 19705
                      carbon group element atom 19614
                        carbon atom 19603
                          organic molecular entity 19603
                            organic group 18537
                              organic divalent group 18528
                                organodiyl group 18528
                                  carbonyl group 18435
                                    carbonyl compound 18435
                                      carboxylic acid 18113
                                        amino acid 14113
                                          alpha-amino acid 11599
                                            alpha-amino acid ester 231
                                              propacetamol 14
paths to the root