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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:perflubutane
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Accession:CHEBI:134964 term browser browse the term
Definition:A fluorocarbon that is butane in which all of the hydrogens have been replaced by fluorines. Microbubbles of preflubutane are used in the ultrasound contrast agent BR14.
Synonyms:exact_synonym: decafluorobutane
 related_synonym: Decafluoro-butane;   Formula=C4F10;   InChI=1S/C4F10/c5-1(6,3(9,10)11)2(7,8)4(12,13)14;   InChIKey=KAVGMUDTWQVPDF-UHFFFAOYSA-N;   SMILES=C(C(C(F)(F)F)(F)F)(C(F)(F)F)(F)F;   Sonazoid;   perflubutano;   perflubutanum;   perfluoro-n-butane;   perfluorobutane
 xref: CAS:355-25-9;   Drug_Central:3999;   KEGG:D05440
 xref_mesh: MESH:C108042
 xref: PMID:28000631;   Reaxys:1777513;   Wikipedia:Perfluorobutane



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perflubutane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot1 acyl-CoA thioesterase 1 increases expression EXP perfluorobutane results in increased expression of ACOT1 mRNA CTD PMID:19407336 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO perfluorobutane results in increased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Apoa2 apolipoprotein A2 affects expression ISO perfluorobutane affects the expression of APOA2 mRNA CTD PMID:23567314 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO perfluorobutane results in decreased expression of CCND1 mRNA CTD PMID:23567314 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO perfluorobutane results in increased expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression ISO perfluorobutane results in increased expression of CPT1B mRNA CTD PMID:23567314 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO perfluorobutane results in increased expression of CYP2B6 mRNA CTD PMID:23567314 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO perfluorobutane results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO perfluorobutane results in increased expression of EHHADH mRNA CTD PMID:23567314 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO perfluorobutane results in increased expression of FABP1 mRNA CTD PMID:23567314 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha affects expression ISO perfluorobutane affects the expression of HADHA mRNA CTD PMID:23567314 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Mogat1 monoacylglycerol O-acyltransferase 1 increases expression ISO perfluorobutane results in increased expression of MOGAT1 mRNA CTD PMID:23567314 NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression ISO perfluorobutane results in increased expression of NOS2 mRNA CTD PMID:23567314 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Pank1 pantothenate kinase 1 increases expression ISO perfluorobutane results in increased expression of PANK1 mRNA CTD PMID:23567314 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluorobutane results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluorobutane results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases expression ISO perfluorobutane results in increased expression of PPARD mRNA CTD PMID:23567314 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO perfluorobutane binds to PPARG protein CTD PMID:24998974 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19911
    chemical entity 19909
      molecular entity 19909
        main group molecular entity 19859
          gas molecular entity 18478
            perflubutane 18
Path 2
Term Annotations click to browse term
  CHEBI ontology 19911
    subatomic particle 19909
      composite particle 19909
        hadron 19909
          baryon 19909
            nucleon 19909
              atomic nucleus 19909
                atom 19909
                  main group element atom 19859
                    main group molecular entity 19859
                      s-block molecular entity 19692
                        hydrogen molecular entity 19678
                          hydrides 19156
                            organic hydride 18707
                              organic fundamental parent 18707
                                hydrocarbon 18438
                                  halohydrocarbon 15511
                                    haloalkane 12294
                                      fluoroalkane 8090
                                        perflubutane 18
paths to the root