CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: flurotyl
Accession: CHEBI:134824
browse the term
Synonyms: related_synonym: Formula=C4H4F6O; InChI=1S/C4H4F6O/c5-3(6,7)1-11-2-4(8,9)10/h1-2H2; InChIKey=KGPPDNUWZNWPSI-UHFFFAOYSA-N; SMILES=FC(F)(F)COCC(F)(F)F; fluorothyl; fluroethyl; flurothyl; hexafluorodiethyl ether
xref: CAS:333-36-8; Drug_Central:3241
xref_mesh: MESH:D005481
G
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
decreases expression
EXP
Flurothyl results in decreased expression of CAMK2A mRNA
CTD
PMID:19059322
NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
G
Gabra1
gamma-aminobutyric acid type A receptor subunit alpha 1
multiple interactions
EXP
Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]
CTD
PMID:11090101
NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
G
Gabrb1
gamma-aminobutyric acid type A receptor subunit beta1
multiple interactions
EXP
Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]
CTD
PMID:11090101
NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
G
Gabrg2
gamma-aminobutyric acid type A receptor subunit gamma 2
multiple interactions
EXP
Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]
CTD
PMID:11090101
NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
G
Gstp1
glutathione S-transferase pi 1
multiple interactions
ISO
Flurothyl inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]
CTD
PMID:23769903
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Plppr4
phospholipid phosphatase related 4
increases expression
EXP
Flurothyl results in increased expression of PLPPR4 protein
CTD
PMID:20167268
NCBI chr 2:205,371,317...205,412,302
Ensembl chr 2:205,371,322...205,412,302
G
Slc30a1
solute carrier family 30 member 1
decreases expression
EXP
Flurothyl results in decreased expression of SLC30A1 mRNA
CTD
PMID:19059322 PMID:20167268
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
G
Slc30a3
solute carrier family 30 member 3
affects expression
EXP
Flurothyl affects the expression of SLC30A3 mRNA
CTD
PMID:20167268
NCBI chr 6:25,264,310...25,284,720
Ensembl chr 6:25,275,528...25,284,720
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