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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:flurotyl
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Accession:CHEBI:134824 term browser browse the term
Synonyms:related_synonym: Formula=C4H4F6O;   InChI=1S/C4H4F6O/c5-3(6,7)1-11-2-4(8,9)10/h1-2H2;   InChIKey=KGPPDNUWZNWPSI-UHFFFAOYSA-N;   SMILES=FC(F)(F)COCC(F)(F)F;   fluorothyl;   fluroethyl;   flurothyl;   hexafluorodiethyl ether
 xref: CAS:333-36-8;   Drug_Central:3241
 xref_mesh: MESH:D005481


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flurotyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression EXP Flurothyl results in decreased expression of CAMK2A mRNA CTD PMID:19059322 NCBI chr18:54,378,642...54,441,120 JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions EXP Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein] CTD PMID:11090101 NCBI chr10:26,595,151...26,650,611 JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions EXP Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein] CTD PMID:11090101 NCBI chr14:36,068,725...36,548,946 JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions EXP Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein] CTD PMID:11090101 NCBI chr10:26,376,805...26,463,680 JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Flurothyl inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230 JBrowse link
G Plppr4 phospholipid phosphatase related 4 increases expression EXP Flurothyl results in increased expression of PLPPR4 protein CTD PMID:20167268 NCBI chr 2:205,371,317...205,412,302 JBrowse link
G Slc30a1 solute carrier family 30 member 1 decreases expression EXP Flurothyl results in decreased expression of SLC30A1 mRNA CTD PMID:19059322 PMID:20167268 NCBI chr13:103,491,037...103,494,910 JBrowse link
G Slc30a3 solute carrier family 30 member 3 affects expression EXP Flurothyl affects the expression of SLC30A3 mRNA CTD PMID:20167268 NCBI chr 6:25,264,310...25,284,720 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19762
    chemical entity 19762
      atom 19760
        nonmetal atom 19641
          oxygen atom 19353
            oxygen molecular entity 19353
              organooxygen compound 18894
                ether 16903
                  flurotyl 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19762
    subatomic particle 19760
      composite particle 19760
        hadron 19760
          baryon 19760
            nucleon 19760
              atomic nucleus 19760
                atom 19760
                  main group element atom 19651
                    p-block element atom 19651
                      carbon group element atom 19570
                        carbon atom 19560
                          organic molecular entity 19560
                            heteroorganic entity 19203
                              organochalcogen compound 18961
                                organooxygen compound 18894
                                  ether 16903
                                    flurotyl 8
paths to the root