avobenzone - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	avobenzone	go back to main search page
Accession:	CHEBI:134751	browse the term
Synonyms:	related_synonym:	Formula=C20H22O3; InChI=1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3; InChIKey=XNEFYCZVKIDDMS-UHFFFAOYSA-N; SMILES=C(CC(=O)C1=CC=C(C=C1)OC)(=O)C2=CC=C(C=C2)C(C)(C)C; butylmethoxydibenzoylmethane; photoplex
	xref:	CAS:70356-09-1; Drug_Central:4242
	xref_mesh:	MESH:C049935

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Genes (437)

avobenzone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

arylacetamide deacetylase-like 2

decreases expression

avobenzone results in decreased expression of AADACL2 mRNA

NCBI chr 2:144,123,557...144,144,159

G

aminoadipate-semialdehyde synthase

increases expression

avobenzone results in increased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

ATP binding cassette subfamily A member 12

decreases expression

avobenzone results in decreased expression of ABCA12 mRNA

NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049

G

abhydrolase domain containing 3, phospholipase

increases expression

avobenzone results in increased expression of ABHD3 mRNA

NCBI chr18:1,723,203...1,778,488
Ensembl chr18:1,720,718...1,803,428

G

acetyl-CoA acetyltransferase 2

increases expression

avobenzone results in increased expression of ACAT2 mRNA

NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821

G

ATP citrate lyase

increases expression

avobenzone results in increased expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

acyl-CoA synthetase short-chain family member 2

increases expression

avobenzone results in increased expression of ACSS2 mRNA

NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675

G

ADAM metallopeptidase with thrombospondin type 1 motif, 1

increases expression

avobenzone results in increased expression of ADAMTS1 mRNA

NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103

G

adhesion G protein-coupled receptor E5

increases expression

avobenzone results in increased expression of ADGRE5 mRNA

NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638

G

adiponectin, C1Q and collagen domain containing

multiple interactions

avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; T 0070907 affects the reaction [avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]

PMID:31016361 PMID:32407875

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

actin filament associated protein 1

increases expression

avobenzone results in increased expression of AFAP1 mRNA

NCBI chr14:74,743,322...74,856,300
Ensembl chr14:74,743,320...74,856,263

G

allograft inflammatory factor 1-like

decreases expression

avobenzone results in decreased expression of AIF1L mRNA

NCBI chr 3:15,229,476...15,254,033
Ensembl chr 3:15,229,524...15,254,023

G

aldo-keto reductase family 1, member C1

increases expression

avobenzone results in increased expression of AKR1C1 mRNA

NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326

G

aldo-keto reductase family 1, member C2

increases expression

avobenzone results in increased expression of AKR1C2 mRNA

NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764

G

aldo-keto reductase family 1, member C3

increases expression

avobenzone results in increased expression of AKR1C3 mRNA

NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873

G

aldehyde dehydrogenase 6 family, member A1

increases expression

avobenzone results in increased expression of ALDH6A1 mRNA

NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656

G

angiogenin

increases expression

avobenzone results in increased expression of ANG mRNA

NCBI chr15:24,312,711...24,323,361

G

ankyrin 2

decreases expression

avobenzone results in decreased expression of ANK2 mRNA

NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923

G

ANTXR cell adhesion molecule 1

increases expression

avobenzone results in increased expression of ANTXR1 mRNA

NCBI chr 4:119,590,770...119,778,232
Ensembl chr 4:119,590,771...119,778,232

G

aminopeptidase O

decreases expression

avobenzone results in decreased expression of AOPEP mRNA

NCBI chr17:1,811,281...2,127,316
Ensembl chr17:1,811,980...2,127,331

G

androgen receptor

affects binding
multiple interactions

avobenzone binds to AR protein
avobenzone binds to and results in decreased activity of AR protein

PMID:15537743 PMID:28115641

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

A-Raf proto-oncogene, serine/threonine kinase

increases expression

avobenzone results in increased expression of ARAF mRNA

NCBI chr X:1,227,392...1,292,356
Ensembl chr X:1,227,392...1,239,073

G

Rho GTPase activating protein 26

decreases expression

avobenzone results in decreased expression of ARHGAP26 mRNA

NCBI chr18:30,835,806...31,237,945
Ensembl chr18:30,838,671...31,235,194

G

AT-rich interaction domain 3B

increases expression

avobenzone results in increased expression of ARID3B mRNA

NCBI chr 8:58,193,268...58,240,901
Ensembl chr 8:58,193,418...58,238,318

G

asparagine synthetase (glutamine-hydrolyzing)

decreases expression

avobenzone results in decreased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

aspartate-beta-hydroxylase

increases expression

avobenzone results in increased expression of ASPH mRNA

NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876

G

aspartate beta-hydroxylase domain containing 2

decreases expression

avobenzone results in decreased expression of ASPHD2 mRNA

NCBI chr12:44,248,132...44,258,653
Ensembl chr12:44,248,145...44,257,772

G

argininosuccinate synthase 1

decreases expression

avobenzone results in decreased expression of ASS1 mRNA

NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903

G

ATPase phospholipid transporting 10B

decreases expression

avobenzone results in decreased expression of ATP10B mRNA

NCBI chr10:27,495,207...27,751,313
Ensembl chr10:27,408,747...27,749,637

G

ATPase H+ transporting V0 subunit D2

increases expression

avobenzone results in increased expression of ATP6V0D2 mRNA

NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354

G

BMP and activin membrane-bound inhibitor

decreases expression

avobenzone results in decreased expression of BAMBI mRNA

NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060

G

Bardet-Biedl syndrome 12

decreases expression

avobenzone results in decreased expression of BBS12 mRNA

NCBI chr 2:120,203,396...120,221,024
Ensembl chr 2:120,203,428...120,219,255

G

BCAR3 adaptor protein, NSP family member

increases expression

avobenzone results in increased expression of BCAR3 mRNA

NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798

G

BCDIN3 domain containing RNA methyltransferase

decreases expression

avobenzone results in decreased expression of BCDIN3D mRNA

NCBI chr 7:130,605,540...130,610,134
Ensembl chr 7:130,605,541...130,610,115

G

BCL6B, transcription repressor

decreases expression

avobenzone results in decreased expression of BCL6B mRNA

NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974

G

BRD3 opposite strand

decreases expression

avobenzone results in decreased expression of BRD3OS mRNA

NCBI chr 3:10,770,229...10,771,860

G

BTB domain containing 7

decreases expression
multiple interactions

avobenzone results in decreased expression of BTBD7 mRNA
avobenzone inhibits the reaction [IFI27 mRNA results in increased expression of BTBD7 mRNA]; IFI27 mRNA inhibits the reaction [avobenzone results in decreased expression of BTBD7 mRNA]

NCBI chr 6:121,920,365...122,010,114
Ensembl chr 6:121,923,023...121,972,405

G

similar to human chromosome 8 open reading frame 48

decreases expression

avobenzone results in decreased expression of C8ORF48 mRNA

NCBI chr16:55,244,744...55,246,642
Ensembl chr16:55,236,322...55,246,650

G

similar to human chromosome 6 open reading frame 120

decreases expression

avobenzone results in decreased expression of C6ORF120 mRNA

NCBI chr 1:55,950,449...55,953,173
Ensembl chr 1:55,949,814...55,963,333

G

similar to human chromosome 8 open reading frame 88

increases expression

avobenzone results in increased expression of C8ORF88 mRNA

NCBI chr 5:28,330,167...28,355,691
Ensembl chr 5:28,330,206...28,357,152

G

similar to human chromosome 11 open reading frame 71

decreases expression

avobenzone results in decreased expression of C11ORF71 mRNA

NCBI chr 8:48,838,556...48,838,970
Ensembl chr 8:48,838,100...48,842,270

G

calcium homeostasis modulator family member 6

increases expression

avobenzone results in increased expression of CALHM6 mRNA

NCBI chr20:26,095,591...26,097,336
Ensembl chr20:26,095,592...26,097,278

G

calmodulin-like 5

decreases expression

avobenzone results in decreased expression of CALML5 mRNA

NCBI chr17:66,394,433...66,395,352

G

calreticulin

increases expression

avobenzone results in increased expression of CALR mRNA

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

calcium/calmodulin-dependent protein kinase ID

decreases expression

avobenzone results in decreased expression of CAMK1D mRNA

NCBI chr17:72,581,899...72,982,704
Ensembl chr17:72,581,979...72,980,556

G

cystathionine beta synthase

decreases expression

avobenzone results in decreased expression of CBS mRNA

NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764

G

collagen and calcium binding EGF domains 1

increases expression

avobenzone results in increased expression of CCBE1 mRNA

NCBI chr18:59,579,851...59,823,977
Ensembl chr18:59,580,768...59,824,400

G

coiled-coil domain containing 125

decreases expression

avobenzone results in decreased expression of CCDC125 mRNA

NCBI chr 2:31,809,120...31,835,538
Ensembl chr 2:31,809,228...31,850,152

G

coiled-coil domain containing 167

increases expression

avobenzone results in increased expression of CCDC167 mRNA

NCBI chr20:7,763,927...7,782,090
Ensembl chr20:7,751,782...7,781,613

G

coiled-coil domain containing 18

decreases expression

avobenzone results in decreased expression of CCDC18 mRNA

NCBI chr14:1,501,749...1,607,672
Ensembl chr14:1,501,784...1,607,711

G

coiled-coil domain containing 71

increases expression

avobenzone results in increased expression of CCDC71 mRNA

NCBI chr 8:109,146,650...109,161,749
Ensembl chr 8:109,146,359...109,165,216

G

cellular communication network factor 1

increases expression

avobenzone results in increased expression of CCN1 mRNA

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cyclin A1

decreases expression

avobenzone results in decreased expression of CCNA1 mRNA

NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157

G

cyclin G2

increases expression

avobenzone results in increased expression of CCNG2 mRNA

NCBI chr14:14,804,321...14,812,819
Ensembl chr14:14,804,322...14,812,830

G

cyclin-dependent kinase 19

increases expression

avobenzone results in increased expression of CDK19 mRNA

NCBI chr20:43,770,409...43,910,629
Ensembl chr20:43,770,409...43,910,628

G

CDKN2A interacting protein N-terminal like

increases expression

avobenzone results in increased expression of CDKN2AIPNL mRNA

NCBI chr10:36,231,134...36,240,569
Ensembl chr10:36,231,087...36,240,564

G

cyclin-dependent kinase inhibitor 2B

decreases expression

avobenzone results in decreased expression of CDKN2B mRNA

NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050

G

cyclin dependent kinase inhibitor 2D

increases expression

avobenzone results in increased expression of CDKN2D mRNA

NCBI chr 8:19,831,874...19,834,640
Ensembl chr 8:19,831,866...19,834,674

G

CCAAT/enhancer binding protein alpha

decreases expression

avobenzone results in decreased expression of CEBPA mRNA

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

centromere protein E

decreases expression

avobenzone results in decreased expression of CENPE mRNA

NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669

G

centrosomal protein 104

increases expression

avobenzone results in increased expression of CEP104 mRNA

NCBI chr 5:164,534,773...164,567,260
Ensembl chr 5:164,534,782...164,567,248

G

carboxylesterase 1D

increases expression

avobenzone results in increased expression of CES1 mRNA

NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035

G

cilia and flagella associated protein 70

decreases expression

avobenzone results in decreased expression of CFAP70 mRNA

NCBI chr15:3,852,381...3,918,036
Ensembl chr15:3,852,509...3,918,014

G

ChaC glutathione-specific gamma-glutamylcyclotransferase 1

decreases expression

avobenzone results in decreased expression of CHAC1 mRNA

NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526

G

ChaC glutathione specific gamma-glutamylcyclotransferase 2

decreases expression

avobenzone results in decreased expression of CHAC2 mRNA

NCBI chr14:104,720,754...104,728,305
Ensembl chr14:104,720,758...104,728,301

G

CHM like Rab escort protein

decreases expression

avobenzone results in decreased expression of CHML mRNA

NCBI chr13:87,609,647...87,619,868
Ensembl chr13:87,589,298...87,619,862

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4

increases expression

avobenzone results in increased expression of CITED4 mRNA

NCBI chr 5:134,246,936...134,247,827
Ensembl chr 5:134,246,682...134,248,135

G

claudin 19

decreases expression

avobenzone results in decreased expression of CLDN19 mRNA

NCBI chr 5:132,862,939...132,870,364
Ensembl chr 5:132,863,267...132,868,227

G

clathrin heavy chain linker domain containing 1

decreases expression

avobenzone results in decreased expression of CLHC1 mRNA

NCBI chr14:103,288,116...103,328,725
Ensembl chr14:103,288,134...103,328,715

G

CAP-GLY domain containing linker protein 2

increases expression

avobenzone results in increased expression of CLIP2 mRNA

NCBI chr12:22,163,044...22,227,023
Ensembl chr12:22,163,218...22,227,023

G

CDC-like kinase 3

increases expression

avobenzone results in increased expression of CLK3 mRNA

NCBI chr 8:58,152,155...58,167,196
Ensembl chr 8:58,152,155...58,168,181

G

chemerin chemokine-like receptor 2

decreases expression

avobenzone results in decreased expression of CMKLR2 mRNA

NCBI chr 9:64,583,310...64,617,883
Ensembl chr 9:64,585,594...64,586,655

G

CKLF-like MARVEL transmembrane domain containing 7

increases expression

avobenzone results in increased expression of CMTM7 mRNA

NCBI chr 8:114,448,037...114,474,958
Ensembl chr 8:114,448,042...114,474,621

G

canopy FGF signaling regulator 3

increases expression

avobenzone results in increased expression of CNPY3 mRNA

NCBI chr 9:14,233,478...14,247,847
Ensembl chr 9:14,233,428...14,247,831

G

consortin, connexin sorting protein

increases expression

avobenzone results in increased expression of CNST mRNA

NCBI chr13:91,296,740...91,373,531
Ensembl chr13:91,296,142...91,373,531

G

cytochrome c oxidase assembly factor COX19

decreases expression

avobenzone results in decreased expression of COX19 mRNA

NCBI chr12:15,303,535...15,313,014
Ensembl chr12:15,303,551...15,313,014

G

CREB3 regulatory factor

increases expression

avobenzone results in increased expression of CREBRF mRNA

NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999

G

cellular repressor of E1A-stimulated genes 2

increases expression

avobenzone results in increased expression of CREG2 mRNA

NCBI chr 9:41,872,000...41,945,413
Ensembl chr 9:41,902,304...41,945,095

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

avobenzone results in increased expression of CYP1A1 mRNA

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily b, polypeptide 1

decreases expression

avobenzone results in decreased expression of CYP1B1 mRNA

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 4, subfamily f, polypeptide 1

decreases expression

avobenzone results in decreased expression of CYP4F12 mRNA

NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046

G

D-box binding PAR bZIP transcription factor

increases expression

avobenzone results in increased expression of DBP mRNA

NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745

G

discoidin, CUB and LCCL domain containing 2

increases expression

avobenzone results in increased expression of DCBLD2 mRNA

NCBI chr11:42,125,525...42,179,927
Ensembl chr11:42,125,787...42,179,697

G

DEAD-box helicase 54

increases expression

avobenzone results in increased expression of DDX54 mRNA

NCBI chr12:35,934,713...35,949,956
Ensembl chr12:35,934,716...35,972,523

G

DEAD-box helicase 59

increases expression

avobenzone results in increased expression of DDX59 mRNA

NCBI chr13:47,876,258...47,901,214
Ensembl chr13:47,876,261...47,901,214

G

2,4-dienoyl-CoA reductase 2

decreases expression

avobenzone results in decreased expression of DECR2 mRNA

NCBI chr10:15,104,907...15,113,281
Ensembl chr10:15,002,926...15,118,479

G

DENN domain containing 5B

increases expression

avobenzone results in increased expression of DENND5B mRNA

NCBI chr 4:181,959,597...182,089,661
Ensembl chr 4:181,961,386...182,089,362

G

diacylglycerol O-acyltransferase 2

decreases expression

avobenzone results in decreased expression of DGAT2 mRNA

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

7-dehydrocholesterol reductase

increases expression

avobenzone results in increased expression of DHCR7 mRNA

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

dehydrogenase/reductase 9

decreases expression

avobenzone results in decreased expression of DHRS9 mRNA

NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241

G

dickkopf WNT signaling pathway inhibitor 1

increases expression

avobenzone results in increased expression of DKK1 mRNA

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

dickkopf WNT signaling pathway inhibitor 3

increases expression

avobenzone results in increased expression of DKK3 mRNA

NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590

G

DnaJ heat shock protein family (Hsp40) member B9

increases expression

avobenzone results in increased expression of DNAJB9 mRNA

NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063

G

DnaJ heat shock protein family (Hsp40) member C30

decreases expression

avobenzone results in decreased expression of DNAJC30 mRNA

NCBI chr12:21,628,319...21,629,398
Ensembl chr12:21,626,450...21,629,408

G

docking protein 7

increases expression

avobenzone results in increased expression of DOK7 mRNA

NCBI chr14:75,665,444...75,699,413
Ensembl chr14:75,666,744...75,699,386

G

desmocollin 1

decreases expression

avobenzone results in decreased expression of DSC1 mRNA

NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494

G

desmoglein 1

decreases expression

avobenzone results in decreased expression of DSG1 mRNA

NCBI chr18:11,674,687...11,705,383
Ensembl chr18:11,674,402...11,703,443

G

dual specificity phosphatase 10

increases expression

avobenzone results in increased expression of DUSP10 mRNA

NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716

G

dual specificity phosphatase 4

increases expression

avobenzone results in increased expression of DUSP4 mRNA

NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138

G

EBP, cholestenol delta-isomerase

increases expression

avobenzone results in increased expression of EBP mRNA

NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826

G

enoyl CoA hydratase domain containing 3

increases expression

avobenzone results in increased expression of ECHDC3 mRNA

NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516

G

extracellular matrix protein 2

decreases expression

avobenzone results in decreased expression of ECM2 mRNA

NCBI chr17:15,120,194...15,152,536
Ensembl chr17:15,120,196...15,152,516

G

epidermal growth factor receptor

increases expression

avobenzone results in increased expression of EGFR mRNA

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

EP300 interacting inhibitor of differentiation 2

decreases expression

avobenzone results in decreased expression of EID2 mRNA

NCBI chr 1:83,538,274...83,539,599

G

eukaryotic translation initiation factor 2 alpha kinase 4

increases expression

avobenzone results in increased expression of EIF2AK4 mRNA

NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630

G

elongator acetyltransferase complex subunit 1

increases expression

avobenzone results in increased expression of ELP1 mRNA

NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762

G

epithelial membrane protein 3

increases expression

avobenzone results in increased expression of EMP3 mRNA

NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988

G

Eph receptor A4

decreases expression

avobenzone results in decreased expression of EPHA4 mRNA

NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139

G

epoxide hydrolase 3

decreases expression

avobenzone results in decreased expression of EPHX3 mRNA

NCBI chr 7:11,206,812...11,212,122
Ensembl chr 7:11,206,812...11,212,122

G

EPM2A interacting protein 1

decreases expression

avobenzone results in decreased expression of EPM2AIP1 mRNA

NCBI chr 8:111,233,871...111,241,219
Ensembl chr 8:111,233,826...111,241,871

G

exoribonuclease 1

increases expression

avobenzone results in increased expression of ERI1 mRNA

NCBI chr16:56,724,101...56,744,228
Ensembl chr16:56,724,115...56,744,226

G

estrogen receptor 1

multiple interactions

avobenzone binds to and results in increased activity of ESR1 protein

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

ETS variant transcription factor 4

increases expression

avobenzone results in increased expression of ETV4 mRNA

NCBI chr10:86,706,749...86,721,974
Ensembl chr10:86,706,749...86,721,974

G

coagulation factor II (thrombin) receptor

increases expression

avobenzone results in increased expression of F2R mRNA

NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870

G

fatty acid binding protein 4

multiple interactions

avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]

PMID:31016361 PMID:32407875

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

family with sequence similarity 185, member A

decreases expression

avobenzone results in decreased expression of FAM185A mRNA

NCBI chr 4:13,542,022...13,662,967
Ensembl chr 4:13,608,464...13,662,967

G

family with sequence similarity 217, member B

increases expression

avobenzone results in increased expression of FAM217B mRNA

NCBI chr 3:165,505,574...165,515,273
Ensembl chr 3:165,501,532...165,513,377

G

family with sequence similarity 241 member A

decreases expression

avobenzone results in decreased expression of FAM241A mRNA

NCBI chr 2:216,344,563...216,375,193
Ensembl chr 2:216,343,822...216,375,242

G

FAM3 metabolism regulating signaling molecule C

increases expression

avobenzone results in increased expression of FAM3C mRNA

NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078

G

family with sequence similarity 43, member A

decreases expression

avobenzone results in decreased expression of FAM43A mRNA

NCBI chr11:70,128,253...70,131,401
Ensembl chr11:70,128,253...70,131,401

G

FA complementation group I

increases expression

avobenzone results in increased expression of FANCI mRNA

NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640

G

fatty acid synthase

increases expression

avobenzone results in increased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

fibrillin 2

increases expression

avobenzone results in increased expression of FBN2 mRNA

NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976

G

F-box and leucine-rich repeat protein 20

increases expression

avobenzone results in increased expression of FBXL20 mRNA

NCBI chr10:83,080,568...83,143,680
Ensembl chr10:83,086,551...83,144,162

G

F-box protein 32

increases expression

avobenzone results in increased expression of FBXO32 mRNA

NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436

G

farnesyl diphosphate farnesyl transferase 1

increases expression

avobenzone results in increased expression of FDFT1 mRNA

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

increases expression

avobenzone results in increased expression of FDPS mRNA

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

FYVE, RhoGEF and PH domain containing 6

increases expression

avobenzone results in increased expression of FGD6 mRNA

NCBI chr 7:28,597,609...28,712,908
Ensembl chr 7:28,597,609...28,712,456

G

fin bud initiation factor homolog

decreases expression

avobenzone results in decreased expression of FIBIN mRNA

NCBI chr 3:96,942,405...96,944,676
Ensembl chr 3:96,942,406...96,944,676

G

filamin A interacting protein 1-like

decreases expression

avobenzone results in decreased expression of FILIP1L mRNA

NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415

G

filaggrin

decreases expression

avobenzone results in decreased expression of FLG mRNA

NCBI chr 2:178,884,793...178,912,986

G

filaggrin 2

decreases expression

avobenzone results in decreased expression of FLG2 mRNA

NCBI chr 2:178,789,792...178,802,232

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression

avobenzone results in decreased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box K1

increases expression

avobenzone results in increased expression of FOXK1 mRNA

NCBI chr12:12,110,119...12,175,089
Ensembl chr12:12,115,950...12,175,089

G

forkhead box P2

decreases expression

avobenzone results in decreased expression of FOXP2 mRNA

NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683

G

FRY microtubule binding protein

decreases expression

avobenzone results in decreased expression of FRY mRNA

NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116

G

frizzled class receptor 2

increases expression

avobenzone results in increased expression of FZD2 mRNA

NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334

G

GABA type A receptor associated protein like 1

increases expression

avobenzone results in increased expression of GABARAPL1 mRNA

NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450

G

golgi associated kinase 1B

increases expression

avobenzone results in increased expression of GASK1B mRNA

NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477

G

glycine C-acetyltransferase

increases expression

avobenzone results in increased expression of GCAT mRNA

NCBI chr 7:110,595,126...110,601,474
Ensembl chr 7:110,595,091...110,601,473

G

GTP cyclohydrolase I feedback regulator

increases expression

avobenzone results in increased expression of GCHFR mRNA

NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080

G

ganglioside-induced differentiation-associated-protein 1

decreases expression

avobenzone results in decreased expression of GDAP1 mRNA

NCBI chr 5:1,932,613...1,951,691
Ensembl chr 5:1,932,613...2,030,061

G

GEN1 Holliday junction 5' flap endonuclease

decreases expression

avobenzone results in decreased expression of GEN1 mRNA

NCBI chr 6:33,947,599...33,978,461
Ensembl chr 6:33,948,206...33,978,401

G

gamma-glutamylamine cyclotransferase

decreases expression

avobenzone results in decreased expression of GGACT mRNA

NCBI chr15:99,969,246...99,998,343
Ensembl chr15:99,968,282...99,993,455

G

gap junction protein, beta 6

decreases expression

avobenzone results in decreased expression of GJB6 mRNA

NCBI chr15:31,284,561...31,294,552
Ensembl chr15:31,284,419...31,294,582

G

glutamate-ammonia ligase

increases expression

avobenzone results in increased expression of GLUL mRNA

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

increases expression

avobenzone results in increased expression of GNE mRNA

NCBI chr 5:58,267,189...58,307,396
Ensembl chr 5:58,267,210...58,307,499

G

glycoprotein nmb

increases expression

avobenzone results in increased expression of GPNMB mRNA

NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367

G

glycogen synthase kinase 3 beta

increases phosphorylation

avobenzone results in increased phosphorylation of GSK3B protein

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

G1 to S phase transition 2

decreases expression

avobenzone results in decreased expression of GSPT2 mRNA

NCBI chr X:59,587,237...59,589,758
Ensembl chr X:59,587,276...59,594,162

G

glutathione S-transferase pi 1

multiple interactions

avobenzone inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

general transcription factor IIIC subunit 2

increases expression

avobenzone results in increased expression of GTF3C2 mRNA

NCBI chr 6:25,196,439...25,221,338
Ensembl chr 6:25,197,268...25,220,490

G

hyaluronan binding protein 4

increases expression

avobenzone results in increased expression of HABP4 mRNA

NCBI chr17:934,931...957,604
Ensembl chr17:935,654...957,565

G

harbinger transposase derived 1

decreases expression

avobenzone results in decreased expression of HARBI1 mRNA

NCBI chr 3:77,681,431...77,689,749
Ensembl chr 3:77,681,431...77,689,724

G

heart development protein with EGF-like domains 1

increases expression

avobenzone results in increased expression of HEG1 mRNA

NCBI chr11:67,006,954...67,095,020
Ensembl chr11:66,957,190...67,095,051

G

HEN methyltransferase 1

decreases expression

avobenzone results in decreased expression of HENMT1 mRNA

NCBI chr 2:196,585,732...196,603,700
Ensembl chr 2:196,586,797...196,599,738

G

hes family bHLH transcription factor 5

decreases expression

avobenzone results in decreased expression of HES5 mRNA

NCBI chr 5:165,522,138...165,523,684
Ensembl chr 5:165,522,234...165,523,001

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

avobenzone results in increased expression of HMGCR mRNA

PMID:31016361 PMID:32407875

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases expression

avobenzone results in increased expression of HMGCS1 mRNA

PMID:31016361 PMID:32407875

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

homeobox and leucine zipper encoding

decreases expression

avobenzone results in decreased expression of HOMEZ mRNA

NCBI chr15:28,321,633...28,339,486
Ensembl chr15:28,320,819...28,339,745

G

heterochromatin protein 1, binding protein 3

increases expression

avobenzone results in increased expression of HP1BP3 mRNA

NCBI chr 5:150,435,781...150,463,004
Ensembl chr 5:150,433,740...150,463,000

G

heparan sulfate-glucosamine 3-sulfotransferase 6

decreases expression

avobenzone results in decreased expression of HS3ST6 mRNA

NCBI chr10:13,781,999...13,788,133
Ensembl chr10:13,781,993...13,788,133

G

hydroxysteroid (17-beta) dehydrogenase 14

increases expression

avobenzone results in increased expression of HSD17B14 mRNA

NCBI chr 1:96,029,224...96,039,577
Ensembl chr 1:96,029,284...96,039,883

G

inhibitor of DNA binding 1

decreases expression

avobenzone results in decreased expression of ID1 mRNA

NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419

G

inhibitor of DNA binding 4

decreases expression

avobenzone results in decreased expression of ID4 mRNA

NCBI chr17:16,389,387...16,391,956
Ensembl chr17:16,389,387...16,392,470

G

isopentenyl-diphosphate delta isomerase 1

increases expression

avobenzone results in increased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

Idnk, gluconokinase

decreases expression

avobenzone results in decreased expression of IDNK mRNA

NCBI chr17:6,483,575...6,490,780
Ensembl chr17:6,483,576...6,490,905

G

interferon, alpha-inducible protein 27

multiple interactions
increases expression

avobenzone inhibits the reaction [IFI27 mRNA results in increased expression of BTBD7 mRNA]; IFI27 mRNA inhibits the reaction [avobenzone results in decreased expression of BTBD7 mRNA]
avobenzone results in increased expression of IFI27 mRNA

NCBI chr 6:122,590,461...122,596,996
Ensembl chr 6:122,590,472...122,779,294

G

interferon, alpha-inducible protein 27 like 2B

increases expression

avobenzone results in increased expression of IFI27L2 mRNA

NCBI chr 6:122,598,872...122,600,358
Ensembl chr 6:122,598,872...122,600,360

G

interferon-induced protein with tetratricopeptide repeats 3

decreases expression

avobenzone results in decreased expression of IFIT3 mRNA

NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307

G

intraflagellar transport 70B

decreases expression

avobenzone results in decreased expression of IFT70B mRNA

NCBI chr 3:60,855,809...60,858,380
Ensembl chr 3:60,855,575...60,858,389

G

insulin-like growth factor binding protein 7

increases expression

avobenzone results in increased expression of IGFBP7 mRNA

NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314

G

IKBKB interacting protein

increases expression

avobenzone results in increased expression of IKBIP mRNA

NCBI chr 7:25,579,865...25,598,548
Ensembl chr 7:25,579,832...25,605,162

G

interleukin 18 receptor 1

decreases expression

avobenzone results in decreased expression of IL18R1 mRNA

NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715

G

interleukin 33

increases expression

avobenzone results in increased expression of IL33 mRNA

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

G

inositol monophosphatase 2

decreases expression

avobenzone results in decreased expression of IMPA2 mRNA

NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641

G

inverted formin 2

increases expression

avobenzone results in increased expression of INF2 mRNA

NCBI chr 6:131,649,162...131,675,944
Ensembl chr 6:131,649,211...131,675,941

G

inhibitor of growth family, member 1

increases expression

avobenzone results in increased expression of ING1 mRNA

NCBI chr16:77,937,276...77,945,320
Ensembl chr16:77,937,279...77,946,264

G

insulin 1

multiple interactions

avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of FABP4 mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA]

NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536

G

insulin 2

multiple interactions

[avobenzone co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARA mRNA; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of TNFRSF11B mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of ADIPOQ mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of FABP4 mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARG mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; T 0070907 affects the reaction [avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]

NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775

G

insulin induced gene 1

increases expression

avobenzone results in increased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

insulin receptor substrate 2

increases expression

avobenzone results in increased expression of IRS2 mRNA

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

G

iroquois homeobox 3

decreases expression

avobenzone results in decreased expression of IRX3 mRNA

NCBI chr19:15,211,882...15,215,317
Ensembl chr19:15,211,878...15,215,317

G

inositol-trisphosphate 3-kinase B

increases expression

avobenzone results in increased expression of ITPKB mRNA

NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004

G

junction mediating and regulatory protein, p53 cofactor

increases expression

avobenzone results in increased expression of JMY mRNA

NCBI chr 2:24,662,104...24,730,955
Ensembl chr 2:24,668,854...24,731,006

G

JPX transcript, XIST activator

decreases expression

avobenzone results in decreased expression of JPX mRNA

NCBI chr X:68,511,491...68,665,132

G

Jrk helix-turn-helix protein

increases expression

avobenzone results in increased expression of JRK mRNA

NCBI chr 7:106,590,662...106,595,345
Ensembl chr 7:106,589,484...106,596,371

G

JRK-like

decreases expression

avobenzone results in decreased expression of JRKL mRNA

NCBI chr 8:10,224,172...10,227,068
Ensembl chr 8:10,224,172...10,227,068

G

potassium inwardly-rectifying channel, subfamily J, member 5

decreases expression

avobenzone results in decreased expression of KCNJ5 mRNA

NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518

G

potassium channel tetramerization domain containing 11

decreases expression

avobenzone results in decreased expression of KCTD11 mRNA

NCBI chr10:54,602,575...54,604,738
Ensembl chr10:54,599,754...54,604,760

G

KDEL endoplasmic reticulum protein retention receptor 3

increases expression

avobenzone results in increased expression of KDELR3 mRNA

NCBI chr 7:111,079,236...111,089,463
Ensembl chr 7:111,079,218...111,101,600

G

KLF transcription factor 10

decreases expression

avobenzone results in decreased expression of KLF10 mRNA

NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994

G

KLF transcription factor 16

increases expression

avobenzone results in increased expression of KLF16 mRNA

NCBI chr 7:9,138,503...9,148,322
Ensembl chr 7:9,138,503...9,148,317

G

kelch-like family member 24

increases expression

avobenzone results in increased expression of KLHL24 mRNA

NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636

G

kelch-like family member 9

decreases expression

avobenzone results in decreased expression of KLHL9 mRNA

NCBI chr 5:103,333,747...103,337,931

G

lysine methyltransferase 2D

increases expression

avobenzone results in increased expression of KMT2D mRNA

NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325

G

lysine-rich coiled-coil 1

decreases expression

avobenzone results in decreased expression of KRCC1 mRNA

NCBI chr 4:103,261,642...103,274,672
Ensembl chr 4:103,261,536...103,277,156

G

keratin 1

decreases expression

avobenzone results in decreased expression of KRT1 mRNA

NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844

G

keratin associated protein 8-1

decreases expression

avobenzone results in decreased expression of KRTAP8-1 mRNA

NCBI chr11:28,717,798...28,718,355
Ensembl chr11:28,718,125...28,718,310

G

kynurenine aminotransferase 1

increases expression

avobenzone results in increased expression of KYAT1 mRNA

NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355

G

L3MBTL histone methyl-lysine binding protein 1

increases expression

avobenzone results in increased expression of L3MBTL1 mRNA

NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233

G

lactamase, beta

increases expression

avobenzone results in increased expression of LACTB mRNA

NCBI chr 8:67,571,504...67,587,592
Ensembl chr 8:67,571,500...67,587,539

G

lysosomal-associated membrane protein 3

decreases expression

avobenzone results in decreased expression of LAMP3 mRNA

NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784

G

leucine carboxyl methyltransferase 2

decreases expression

avobenzone results in decreased expression of LCMT2 mRNA

NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084

G

low density lipoprotein receptor

increases expression

avobenzone results in increased expression of LDLR mRNA

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

LIM domain and actin binding 1

increases expression

avobenzone results in increased expression of LIMA1 mRNA

NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473

G

limb and CNS expressed 1 like

increases expression

avobenzone results in increased expression of LIX1L mRNA

NCBI chr 2:184,136,018...184,161,918
Ensembl chr 2:184,136,038...184,161,916

G

leishmanolysin like peptidase

decreases expression

avobenzone results in decreased expression of LMLN mRNA

NCBI chr11:67,656,241...67,725,889
Ensembl chr11:67,658,152...67,724,243

G

ligand of numb-protein X 1

increases expression

avobenzone results in increased expression of LNX1 mRNA

NCBI chr14:33,514,429...33,617,086
Ensembl chr14:33,514,436...33,617,086

G

PRAME family member 12-like

decreases expression

avobenzone results in decreased expression of ZNF585B mRNA

NCBI chr 5:156,009,794...156,012,390
Ensembl chr 5:156,009,836...156,012,357

G

loricrin cornified envelope precursor protein

decreases expression

avobenzone results in decreased expression of LORICRIN mRNA

NCBI chr 2:177,558,062...177,560,960
Ensembl chr 2:177,558,252...177,559,807

G

lysophosphatidylcholine acyltransferase 4

increases expression

avobenzone results in increased expression of LPCAT4 mRNA

NCBI chr 3:99,044,729...99,052,963
Ensembl chr 3:99,044,729...99,052,875

G

lipin 1

increases expression

avobenzone results in increased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

leucine rich repeat containing 8 VRAC subunit D

decreases expression

avobenzone results in decreased expression of LRRC8D mRNA

NCBI chr14:4,029,971...4,134,922
Ensembl chr14:4,029,473...4,135,877

G

lanosterol synthase

increases expression

avobenzone results in increased expression of LSS mRNA

NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762

G

LUC7-like

increases expression

avobenzone results in increased expression of LUC7L mRNA

NCBI chr10:15,273,340...15,307,131
Ensembl chr10:15,273,348...15,303,112

G

lymphocyte antigen 9

increases expression

avobenzone results in increased expression of LY9 mRNA

NCBI chr13:84,079,345...84,100,783
Ensembl chr13:84,079,458...84,100,823

G

Ly6/neurotoxin 1

increases expression

avobenzone results in increased expression of LYNX1 mRNA

NCBI chr 7:106,632,800...106,638,003
Ensembl chr 7:106,632,797...106,638,023

G

Ly6/Plaur domain containing 6B

decreases expression

avobenzone results in decreased expression of LYPD6B mRNA

NCBI chr 3:34,199,101...34,360,770
Ensembl chr 3:34,199,599...34,360,770

G

mab-21 like 3

decreases expression

avobenzone results in decreased expression of MAB21L3 mRNA

NCBI chr 2:189,248,895...189,271,652
Ensembl chr 2:189,248,895...189,271,652

G

MAF bZIP transcription factor B

decreases expression

avobenzone results in decreased expression of MAFB mRNA

NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031

G

MAGE family member D2

increases expression

avobenzone results in increased expression of MAGED2 mRNA

NCBI chr X:19,733,593...19,741,769
Ensembl chr X:19,733,597...19,740,477

G

MAGE family member E1

increases expression

avobenzone results in increased expression of MAGEE1 mRNA

NCBI chr X:70,189,242...70,192,789
Ensembl chr X:70,189,187...70,192,810

G

mastermind-like transcriptional coactivator 3

decreases expression

avobenzone results in decreased expression of MAML3 mRNA

NCBI chr 2:135,720,431...136,137,829
Ensembl chr 2:135,721,021...136,137,814

G

mitogen activated protein kinase 1

increases phosphorylation

avobenzone results in increased phosphorylation of MAPK1 protein

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

increases phosphorylation

avobenzone results in increased phosphorylation of MAPK3 protein

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

metallo-beta-lactamase domain containing 2

decreases expression

avobenzone results in decreased expression of MBLAC2 mRNA

NCBI chr 2:11,986,075...12,028,882
Ensembl chr 2:11,986,027...12,030,950

G

minichromosome maintenance complex component 4

increases expression

avobenzone results in increased expression of MCM4 mRNA

NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144

G

minichromosome maintenance complex component 5

increases expression

avobenzone results in increased expression of MCM5 mRNA

NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389

G

MDM2 proto-oncogene

increases expression

avobenzone results in increased expression of MDM2 mRNA

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

methyltransferase 21A, HSPA lysine

increases expression

avobenzone results in increased expression of METTL21A mRNA

NCBI chr 9:65,934,253...65,999,964
Ensembl chr 9:65,978,051...65,987,550

G

microfibril associated protein 3 like

decreases expression

avobenzone results in decreased expression of MFAP3L mRNA

NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863

G

MIB E3 ubiquitin protein ligase 1

increases expression

avobenzone results in increased expression of MIB1 mRNA

NCBI chr18:1,802,519...1,926,988
Ensembl chr18:1,802,519...1,920,689

G

MICAL-like 2

increases expression

avobenzone results in increased expression of MICALL2 mRNA

NCBI chr12:14,899,188...14,927,949
Ensembl chr12:14,899,157...14,927,946

G

MHC class I polypeptide-related sequence B

increases expression

avobenzone results in increased expression of MICB mRNA

NCBI chr 1:78,495,779...78,513,030
Ensembl chr 1:78,495,779...78,512,827

G

MHC I like leukocyte 1

increases expression

avobenzone results in increased expression of MICA mRNA

NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930

G

matrix metallopeptidase 3

decreases expression

avobenzone results in decreased expression of MMP3 mRNA

NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961

G

meiotic nuclear divisions 1

increases expression

avobenzone results in increased expression of MND1 mRNA

NCBI chr 2:169,433,523...169,496,081
Ensembl chr 2:169,433,540...169,496,096

G

molybdenum cofactor synthesis 3

decreases expression

avobenzone results in decreased expression of MOCS3 mRNA

NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890

G

mortality factor 4 like 1

increases expression

avobenzone results in increased expression of MORF4L1 mRNA

NCBI chr 8:90,642,988...90,664,518
Ensembl chr 8:90,642,988...90,664,519

G

mitochondrial ribosomal protein L39

increases expression

avobenzone results in increased expression of MRPL39 mRNA

NCBI chr11:23,779,655...23,795,146
Ensembl chr11:23,779,662...23,795,125

G

Myb/SANT DNA binding domain containing 3

increases expression

avobenzone results in increased expression of MSANTD3 mRNA

NCBI chr 5:62,866,022...62,892,444
Ensembl chr 5:62,866,022...62,888,859

G

misato mitochondrial distribution and morphology regulator 1

decreases expression

avobenzone results in decreased expression of MSTO1 mRNA

NCBI chr 2:174,305,945...174,310,230
Ensembl chr 2:174,301,861...174,310,216

G

metallothionein 1, pseudogene 3

increases expression

avobenzone results in increased expression of MT1E mRNA

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2A

increases expression

avobenzone results in increased expression of MT2A mRNA

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

mucin 15, cell surface associated

decreases expression

avobenzone results in decreased expression of MUC15 mRNA

NCBI chr 3:97,294,728...97,308,641
Ensembl chr 3:97,294,783...97,307,090

G

mevalonate diphosphate decarboxylase

increases expression

avobenzone results in increased expression of MVD mRNA

NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971

G

myosin IIIB

increases expression

avobenzone results in increased expression of MYO3B mRNA

NCBI chr 3:54,820,225...55,228,518
Ensembl chr 3:54,820,251...55,227,373

G

NEDD4 binding protein 2-like 1

increases expression

avobenzone results in increased expression of N4BP2L1 mRNA

NCBI chr12:102,572...128,352
Ensembl chr12:102,573...127,257

G

nuclear receptor coactivator 5

decreases expression

avobenzone results in decreased expression of NCOA5 mRNA

NCBI chr 3:153,736,420...153,769,838
Ensembl chr 3:153,736,420...153,769,553

G

NDUFA4, mitochondrial complex associated like 2

decreases expression

avobenzone results in decreased expression of NDUFA4L2 mRNA

NCBI chr 7:63,351,021...63,359,010
Ensembl chr 7:63,356,883...63,359,010

G

NEDD4 E3 ubiquitin protein ligase

decreases expression

avobenzone results in decreased expression of NEDD4 mRNA

NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951

G

NHL repeat containing 2

increases expression

avobenzone results in increased expression of NHLRC2 mRNA

NCBI chr 1:255,589,743...255,648,904
Ensembl chr 1:255,589,742...255,651,408

G

NIPA-like domain containing 3

increases expression

avobenzone results in increased expression of NIPAL3 mRNA

NCBI chr 5:147,687,310...147,725,838
Ensembl chr 5:147,685,288...147,726,351

G

NTPase, KAP family P-loop domain containing 1

decreases expression

avobenzone results in decreased expression of NKPD1 mRNA

NCBI chr 1:79,165,642...79,175,126
Ensembl chr 1:79,167,130...79,174,234

G

nocturnin

increases expression

avobenzone results in increased expression of NOCT mRNA

NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400

G

Nodal modulator 1

increases expression

avobenzone results in increased expression of NOMO3 mRNA

NCBI chr 1:96,505,460...96,556,280
Ensembl chr 1:96,505,484...96,556,279

G

neuronal PAS domain protein 2

increases expression

avobenzone results in increased expression of NPAS2 mRNA

NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320

G

aminopeptidase-like 1

decreases expression

avobenzone results in decreased expression of NPEPL1 mRNA

NCBI chr 3:162,893,932...162,906,491
Ensembl chr 3:162,893,943...162,906,492

G

NAD(P)H quinone dehydrogenase 1

increases expression

avobenzone results in increased expression of NQO1 mRNA

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 1, group D, member 2

increases expression

avobenzone results in increased expression of NR1D2 mRNA

NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553

G

nuclear receptor subfamily 3, group C, member 1

affects binding

avobenzone binds to NR3C1 protein

NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375

G

negative regulator of ubiquitin-like proteins 1

increases expression

avobenzone results in increased expression of NUB1 mRNA

NCBI chr 4:10,442,917...10,473,689
Ensembl chr 4:10,442,917...10,473,694

G

NACHT and WD repeat domain containing 2

decreases expression

avobenzone results in decreased expression of NWD2 mRNA

NCBI chr14:44,480,049...44,671,417
Ensembl chr14:44,482,287...44,670,299

G

obscurin like cytoskeletal adaptor 1

increases expression

avobenzone results in increased expression of OBSL1 mRNA

NCBI chr 9:76,967,802...76,993,771
Ensembl chr 9:76,974,253...76,993,560

G

osteoclastogenesis associated transmembrane protein 1

increases expression

avobenzone results in increased expression of OSTM1 mRNA

NCBI chr20:46,071,657...46,187,049
Ensembl chr20:46,153,075...46,187,023

G

OTU deubiquitinase 1

increases expression

avobenzone results in increased expression of OTUD1 mRNA

NCBI chr17:82,259,920...82,262,770
Ensembl chr17:82,259,840...82,262,995

G

purinergic receptor P2X 7

decreases expression

avobenzone results in decreased expression of P2RX7 mRNA

NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619

G

purinergic receptor P2Y1

decreases expression

avobenzone results in decreased expression of P2RY1 mRNA

NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457

G

pappalysin 2

decreases expression

avobenzone results in decreased expression of PAPPA2 mRNA

NCBI chr13:70,873,918...71,147,874
Ensembl chr13:70,876,794...71,147,779

G

3'-phosphoadenosine 5'-phosphosulfate synthase 2

increases expression

avobenzone results in increased expression of PAPSS2 mRNA

NCBI chr 1:230,454,314...230,539,332
Ensembl chr 1:230,454,426...230,539,331

G

par-3 family cell polarity regulator

increases expression

avobenzone results in increased expression of PARD3 mRNA

NCBI chr19:55,080,282...55,630,111
Ensembl chr19:55,080,282...55,629,778

G

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

decreases expression

avobenzone results in decreased expression of PCK2 mRNA

NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283

G

piccolo (presynaptic cytomatrix protein)

decreases expression

avobenzone results in decreased expression of PCLO mRNA

NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885

G

proliferating cell nuclear antigen

decreases expression

avobenzone results in decreased expression of PCNA protein

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

procollagen C-endopeptidase enhancer 2

increases expression

avobenzone results in increased expression of PCOLCE2 mRNA

NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114

G

proprotein convertase subtilisin/kexin type 9

increases expression

avobenzone results in increased expression of PCSK9 mRNA

NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688

G

programmed cell death 5

increases expression

avobenzone results in increased expression of PDCD5 mRNA

NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200

G

phosphodiesterase 5A

increases expression

avobenzone results in increased expression of PDE5A mRNA

NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701

G

protein disulfide isomerase family A, member 4

increases expression

avobenzone results in increased expression of PDIA4 mRNA

NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107

G

pyruvate dehydrogenase kinase 1

increases expression

avobenzone results in increased expression of PDK1 mRNA

NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038

G

pyruvate dehydrogenase phosphatase catalytic subunit 2

increases expression

avobenzone results in increased expression of PDP2 mRNA

NCBI chr19:386,408...394,068
Ensembl chr19:386,406...394,074

G

pyridoxal-dependent decarboxylase domain containing 1

increases expression

avobenzone results in increased expression of PDXDC1 mRNA

NCBI chr10:2,025,056...2,113,712
Ensembl chr10:2,025,360...2,113,520

G

PET100 cytochrome c oxidase chaperone

increases expression

avobenzone results in increased expression of PET100 mRNA

NCBI chr12:1,679,805...1,682,540
Ensembl chr12:1,679,859...1,682,540

G

peroxisomal biogenesis factor 13

increases expression

avobenzone results in increased expression of PEX13 mRNA

NCBI chr14:97,602,829...97,621,233
Ensembl chr14:97,603,539...97,621,262

G

prefoldin subunit 4

increases expression

avobenzone results in increased expression of PFDN4 mRNA

NCBI chr 3:159,303,173...159,311,221
Ensembl chr 3:159,303,071...159,311,219

G

phosphatase and actin regulator 3

decreases expression

avobenzone results in decreased expression of PHACTR3 mRNA

NCBI chr 3:165,205,247...165,423,692
Ensembl chr 3:165,205,255...165,423,153

G

phosphate regulating endopeptidase X-linked

decreases expression

avobenzone results in decreased expression of PHEX mRNA

NCBI chr X:37,607,553...37,856,183
Ensembl chr X:37,610,760...37,854,469

G

putative homeodomain transcription factor 2

increases expression

avobenzone results in increased expression of PHTF2 mRNA

NCBI chr 4:14,215,190...14,330,549
Ensembl chr 4:14,215,263...14,330,513

G

phosphatidylinositol 4-kinase type 2 alpha

increases expression

avobenzone results in increased expression of PI4K2A mRNA

NCBI chr 1:240,902,804...240,929,234
Ensembl chr 1:240,902,855...240,929,337

G

p53-induced death domain protein 1

increases expression

avobenzone results in increased expression of PIDD1 mRNA

NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699

G

phosphatidylinositol glycan anchor biosynthesis, class M

decreases expression

avobenzone results in decreased expression of PIGM mRNA

NCBI chr13:84,838,329...84,842,026
Ensembl chr13:84,838,175...84,843,381

G

phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha

increases expression

avobenzone results in increased expression of PIK3C2A mRNA

NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472

G

phosphoinositide-3-kinase interacting protein 1

increases expression

avobenzone results in increased expression of PIK3IP1 mRNA

NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608

G

paired immunoglobin like type 2 receptor beta 2 like 8

decreases expression

avobenzone results in decreased expression of ZNF37A mRNA

NCBI chr12:17,744,315...17,756,074
Ensembl chr12:17,752,830...17,755,922

G

plasminogen activator, urokinase

increases expression

avobenzone results in increased expression of PLAU mRNA

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

pleckstrin homology and RhoGEF domain containing G3

increases expression

avobenzone results in increased expression of PLEKHG3 mRNA

NCBI chr 6:95,265,756...95,308,952
Ensembl chr 6:95,266,058...95,310,359

G

perilipin 2

decreases expression

avobenzone results in decreased expression of PLIN2 mRNA

NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319

G

phospholipid phosphatase 6

decreases expression

avobenzone results in decreased expression of PLPP6 mRNA

NCBI chr 1:226,679,100...226,681,952
Ensembl chr 1:226,679,100...226,681,949

G

PNN interacting serine and arginine rich protein

increases expression

avobenzone results in increased expression of PNISR mRNA

NCBI chr 5:35,395,965...35,422,852
Ensembl chr 5:35,395,965...35,422,844

G

RNA polymerase I subunit H, antisense

decreases expression

avobenzone results in decreased expression of POLR1HASP mRNA

NCBI chr 9:16,098,624...16,099,790
Ensembl chr 9:16,098,624...16,099,790

G

peroxisome proliferator activated receptor alpha

increases expression
multiple interactions

avobenzone results in increased expression of PPARA mRNA
[avobenzone co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARA mRNA

PMID:31016361 PMID:32407875

NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor gamma

multiple interactions
increases expression

avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of PPARG mRNA]; avobenzone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA]
avobenzone results in increased expression of PPARG mRNA

PMID:31016361 PMID:32407875

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PPFIA binding protein 1

increases expression

avobenzone results in increased expression of PPFIBP1 mRNA

NCBI chr 4:179,807,579...179,951,428
Ensembl chr 4:179,808,794...179,951,428

G

protein phosphatase, Mg2+/Mn2+ dependent, 1K

increases expression

avobenzone results in increased expression of PPM1K mRNA

NCBI chr 4:87,612,198...87,638,993
Ensembl chr 4:87,612,204...87,636,152

G

protein phosphatase 1, regulatory subunit 18

increases expression

avobenzone results in increased expression of PPP1R18 mRNA

NCBI chr20:2,877,567...2,887,526
Ensembl chr20:2,877,567...2,891,802

G

protein phosphatase 1, regulatory subunit 3C

decreases expression

avobenzone results in decreased expression of PPP1R3C mRNA

NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961

G

protein kinase cGMP-dependent 1

decreases expression

avobenzone results in decreased expression of PRKG1 mRNA

NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080

G

protein arginine methyltransferase 2

increases expression

avobenzone results in increased expression of PRMT2 mRNA

NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643

G

protein arginine methyltransferase 6

decreases expression

avobenzone results in decreased expression of PRMT6 mRNA

NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648

G

protein arginine methyltransferase 8

decreases expression

avobenzone results in decreased expression of PRMT8 mRNA

NCBI chr 4:160,535,813...160,618,193
Ensembl chr 4:160,535,813...160,617,930

G

serine protease 23

decreases expression

avobenzone results in decreased expression of PRSS23 mRNA

NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091

G

phosphoserine aminotransferase 1

decreases expression

avobenzone results in decreased expression of PSAT1 mRNA

NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682

G

protein serine kinase H1

decreases expression

avobenzone results in decreased expression of PSKH1 mRNA

NCBI chr19:33,794,919...33,827,040
Ensembl chr19:33,794,935...33,827,032

G

platelet-activating factor receptor

increases expression

avobenzone results in increased expression of PTAFR mRNA

NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251

G

protein tyrosine phosphatase domain containing 1

increases expression

avobenzone results in increased expression of PTPDC1 mRNA

NCBI chr17:16,028,964...16,076,512
Ensembl chr17:16,049,382...16,076,512

G

quinolinate phosphoribosyltransferase

increases expression

avobenzone results in increased expression of QPRT mRNA

NCBI chr 1:181,718,189...181,733,486
Ensembl chr 1:181,718,190...181,733,486

G

RAB11 family interacting protein 4

increases expression

avobenzone results in increased expression of RAB11FIP4 mRNA

NCBI chr10:64,550,109...64,658,123
Ensembl chr10:64,550,177...64,654,759

G

Rac family small GTPase 2

increases expression

avobenzone results in increased expression of RAC2 mRNA

NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720

G

RAD18 E3 ubiquitin protein ligase

increases expression

avobenzone results in increased expression of RAD18 mRNA

NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069

G

retinoic acid early transcript 1E

decreases expression

avobenzone results in decreased expression of RAET1E mRNA

NCBI chr 1:1,662,665...1,664,609
Ensembl chr 1:1,807,644...1,812,755

G

RAN binding protein 1

increases expression

avobenzone results in increased expression of RANBP1 mRNA

NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838

G

RAN binding protein 6

decreases expression

avobenzone results in decreased expression of RANBP6 mRNA

NCBI chr 1:227,572,394...227,576,915
Ensembl chr 1:227,572,105...227,576,942

G

RAS guanyl releasing protein 1

decreases expression

avobenzone results in decreased expression of RASGRP1 mRNA

NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056

G

Ras association domain family member 10

decreases expression

avobenzone results in decreased expression of RASSF10 mRNA

NCBI chr 1:167,058,277...167,063,591
Ensembl chr 1:167,058,099...167,063,572

G

RB transcriptional corepressor like 2

increases expression

avobenzone results in increased expression of RBL2 mRNA

NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572

G

RNA binding motif protein 45

decreases expression

avobenzone results in decreased expression of RBM45 mRNA

NCBI chr 3:61,305,973...61,320,950
Ensembl chr 3:61,305,924...61,320,952

G

RNA binding motif protein 5

increases expression

avobenzone results in increased expression of RBM5 mRNA

NCBI chr 8:108,420,220...108,449,481
Ensembl chr 8:108,420,222...108,449,430

G

regulator of G-protein signaling 5

decreases expression

avobenzone results in decreased expression of RGS5 mRNA

NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518

G

ribonuclease A family member 4

increases expression

avobenzone results in increased expression of RNASE4 mRNA

NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117

G

ring finger protein 6

increases expression

avobenzone results in increased expression of RNF6 mRNA

NCBI chr12:8,816,797...8,826,870
Ensembl chr12:8,816,833...8,826,847

G

ribosomal protein S6

increases phosphorylation

avobenzone results in increased phosphorylation of RPS6 protein

NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602

G

ribosomal protein S6 kinase A6

decreases expression

avobenzone results in decreased expression of RPS6KA6 mRNA

NCBI chr X:76,353,316...76,454,502
Ensembl chr X:76,353,760...76,454,484

G

ribosomal protein S6 kinase B1

increases phosphorylation

avobenzone results in increased phosphorylation of RPS6KB1 protein

NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908

G

repetin

decreases expression

avobenzone results in decreased expression of RPTN mRNA

NCBI chr 2:179,061,768...179,066,056
Ensembl chr 2:179,060,017...179,065,910

G

Ras-related GTP binding D

increases expression

avobenzone results in increased expression of RRAGD mRNA

NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356

G

radical S-adenosyl methionine domain containing 2

increases expression

avobenzone results in increased expression of RSAD2 mRNA

NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699

G

round spermatid basic protein 1-like

increases expression

avobenzone results in increased expression of RSBN1L mRNA

NCBI chr 4:14,138,076...14,203,972
Ensembl chr 4:14,139,031...14,201,147

G

RUN domain containing 1

decreases expression

avobenzone results in decreased expression of RUNDC1 mRNA

NCBI chr10:86,361,635...86,375,446
Ensembl chr10:86,361,051...86,370,878

G

sterile alpha motif domain containing 13

decreases expression

avobenzone results in decreased expression of SAMD13 mRNA

NCBI chr 2:235,534,699...235,540,527
Ensembl chr 2:235,534,702...235,567,615

G

sterile alpha motif domain containing 4A

increases expression

avobenzone results in increased expression of SAMD4A mRNA

NCBI chr15:20,135,994...20,352,131
Ensembl chr15:20,134,377...20,348,380

G

sterile alpha motif domain containing 9

decreases expression

avobenzone results in decreased expression of SAMD9 mRNA

NCBI chr 4:31,164,639...31,184,278
Ensembl chr 4:31,164,510...31,184,322

G

sterile alpha motif domain containing 9 like

decreases expression

avobenzone results in decreased expression of SAMD9L mRNA

NCBI chr 4:31,362,054...31,376,412
Ensembl chr 4:31,361,669...31,376,415

G

scavenger receptor class A, member 3

increases expression

avobenzone results in increased expression of SCARA3 mRNA

NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894

G

stearoyl-CoA desaturase

increases expression

avobenzone results in increased expression of SCD mRNA

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

Scm polycomb group protein like 1

increases expression

avobenzone results in increased expression of SCML1 mRNA

NCBI chr X:32,893,100...32,912,686
Ensembl chr X:32,894,327...32,911,366

G

stromal cell-derived factor 2-like 1

increases expression

avobenzone results in increased expression of SDF2L1 mRNA

NCBI chr11:83,872,659...83,874,902
Ensembl chr11:83,872,659...83,874,902

G

SEC24 homolog D, COPII coat complex component

increases expression

avobenzone results in increased expression of SEC24D mRNA

NCBI chr 2:211,418,557...211,526,588
Ensembl chr 2:211,418,623...211,526,587

G

semaphorin 6D

decreases expression

avobenzone results in decreased expression of SEMA6D mRNA

NCBI chr 3:111,883,415...111,941,100
Ensembl chr 3:111,883,872...111,941,094

G

selenophosphate synthetase 2

decreases expression

avobenzone results in decreased expression of SEPHS2 mRNA

NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497

G

SFT2 domain containing 3

decreases expression

avobenzone results in decreased expression of SFT2D3 mRNA

NCBI chr18:23,537,105...23,539,305
Ensembl chr18:23,537,105...23,539,305

G

SH3 domain binding glutamate-rich protein

decreases expression

avobenzone results in decreased expression of SH3BGR mRNA

NCBI chr11:35,503,663...35,527,853
Ensembl chr11:35,503,725...35,527,853

G

solute carrier family 12, member 6

increases expression

avobenzone results in increased expression of SLC12A6 mRNA

NCBI chr 3:99,071,577...99,170,266
Ensembl chr 3:99,071,391...99,170,258

G

solute carrier family 16, member 9

decreases expression

avobenzone results in decreased expression of SLC16A9 mRNA

NCBI chr20:18,335,862...18,377,125
Ensembl chr20:18,335,862...18,377,022

G

solute carrier family 17 member 5

increases expression

avobenzone results in increased expression of SLC17A5 mRNA

NCBI chr 8:79,394,416...79,429,387

G

solute carrier family 25 member 37

increases expression

avobenzone results in increased expression of SLC25A37 mRNA

NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199

G

solute carrier family 2 member 12

increases expression

avobenzone results in increased expression of SLC2A12 mRNA

NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971

G

solute carrier family 2 member 3

increases expression

avobenzone results in increased expression of SLC2A3 mRNA

NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472

G

solute carrier family 2 member 8

increases expression

avobenzone results in increased expression of SLC2A8 mRNA

NCBI chr 3:16,274,918...16,284,536
Ensembl chr 3:16,274,925...16,284,464

G

solute carrier family 33 member 1

increases expression

avobenzone results in increased expression of SLC33A1 mRNA

NCBI chr 2:148,415,660...148,438,182
Ensembl chr 2:148,415,666...148,437,758

G

solute carrier family 5 member 3

increases expression

avobenzone results in increased expression of SLC5A3 mRNA

NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883

G

solute carrier family 6 member 6

increases expression

avobenzone results in increased expression of SLC6A6 mRNA

NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875

G

small integral membrane protein 5

decreases expression

avobenzone results in decreased expression of SMIM5 mRNA

NCBI chr10:101,134,033...101,139,814
Ensembl chr10:101,134,033...101,139,813

G

smoothelin

increases expression

avobenzone results in increased expression of SMTN mRNA

NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886

G

small nuclear ribonucleoprotein U4/U6.U5 subunit 27

increases expression

avobenzone results in increased expression of SNRNP27 mRNA

NCBI chr 4:119,123,676...119,133,234
Ensembl chr 4:119,121,877...119,133,234

G

suppressor of cytokine signaling 3

increases expression

avobenzone results in increased expression of SOCS3 mRNA

NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787

G

suppressor of cytokine signaling 4

decreases expression

avobenzone results in decreased expression of SOCS4 mRNA

NCBI chr15:20,523,406...20,537,889
Ensembl chr15:20,523,183...20,542,494

G

SRY-box transcription factor 9

increases expression

avobenzone results in increased expression of SOX9 mRNA

NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994

G

secreted protein acidic and cysteine rich

increases expression

avobenzone results in increased expression of SPARC mRNA

NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396

G

serine peptidase inhibitor, Kazal type 6

increases expression

avobenzone results in increased expression of SPINK6 mRNA

NCBI chr18:36,397,833...36,410,010
Ensembl chr18:36,397,910...36,409,819

G

squalene epoxidase

increases expression

avobenzone results in increased expression of SQLE mRNA

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

G

sequestosome 1

increases expression

avobenzone results in increased expression of SQSTM1 mRNA

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

stanniocalcin 2

decreases expression

avobenzone results in decreased expression of STC2 mRNA

NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973

G

serine/threonine kinase 32C

increases expression

avobenzone results in increased expression of STK32C mRNA

NCBI chr 1:193,900,718...193,981,723
Ensembl chr 1:193,900,718...193,981,723

G

syntaxin 19

decreases expression

avobenzone results in decreased expression of STX19 mRNA

NCBI chr11:172,855...178,053
Ensembl chr11:171,395...179,191

G

succinylCoA:glutarate-CoA transferase

increases expression

avobenzone results in increased expression of SUGCT mRNA

NCBI chr17:47,376,392...48,234,362
Ensembl chr17:47,376,521...48,234,376

G

sulfotransferase family 1E member 1

decreases expression

avobenzone results in decreased expression of SULT1E1 mRNA

NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275

G

sulfite oxidase

decreases expression

avobenzone results in decreased expression of SUOX mRNA

NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038

G

syntabulin

decreases expression

avobenzone results in decreased expression of SYBU mRNA

NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828

G

syncoilin, intermediate filament protein

decreases expression

avobenzone results in decreased expression of SYNC mRNA

NCBI chr 5:141,631,837...141,656,184
Ensembl chr 5:141,632,367...141,688,659

G

TATA-box binding protein associated factor 13

increases expression

avobenzone results in increased expression of TAF13 mRNA

NCBI chr 2:196,205,219...196,215,882
Ensembl chr 2:196,205,243...196,215,878

G

TBC1 domain family, member 2

increases expression

avobenzone results in increased expression of TBC1D2 mRNA

NCBI chr 5:60,884,114...60,931,717
Ensembl chr 5:60,884,124...60,931,352

G

terminal nucleotidyltransferase 5C

increases expression

avobenzone results in increased expression of TENT5C mRNA

NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744

G

tissue factor pathway inhibitor 2

increases expression

avobenzone results in increased expression of TFPI2 mRNA

NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600

G

transforming growth factor, beta receptor 2

increases expression

avobenzone results in increased expression of TGFBR2 mRNA

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

G

transglutaminase 1

decreases expression

avobenzone results in decreased expression of TGM1 mRNA

NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523

G

thymocyte selection associated family member 2

increases expression

avobenzone results in increased expression of THEMIS2 mRNA

NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400

G

transmembrane 9 superfamily member 1

increases expression

avobenzone results in increased expression of TM9SF1 mRNA

NCBI chr15:29,127,585...29,135,334
Ensembl chr15:29,127,584...29,135,349

G

transmembrane protein 139

decreases expression

avobenzone results in decreased expression of TMEM139 mRNA

NCBI chr 4:71,147,072...71,149,151
Ensembl chr 4:71,146,724...71,167,399

G

transmembrane protein 185B

decreases expression

avobenzone results in decreased expression of TMEM185B mRNA

NCBI chr13:30,647,533...30,650,864
Ensembl chr13:30,647,482...30,650,858

G

transmembrane protein 250

decreases expression

avobenzone results in decreased expression of TMEM250 mRNA

NCBI chr 3:8,962,657...8,966,349
Ensembl chr 3:8,962,657...8,966,349

G

transmembrane protein 67

decreases expression

avobenzone results in decreased expression of TMEM67 mRNA

NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334

G

transmembrane protein 97

increases expression

avobenzone results in increased expression of TMEM97 mRNA

NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730

G

TNF receptor superfamily member 11B

multiple interactions

avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased expression of TNFRSF11B mRNA]; avobenzone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]

NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538

G

TNF superfamily member 9

increases expression

avobenzone results in increased expression of TNFSF9 mRNA

NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345

G

DNA topoisomerase III beta

increases expression

avobenzone results in increased expression of TOP3B mRNA

NCBI chr11:84,097,018...84,125,474
Ensembl chr11:84,097,026...84,125,392

G

translocation associated membrane protein 1-like 1

decreases expression

avobenzone results in decreased expression of TRAM1L1 mRNA

NCBI chr 2:212,511,130...212,513,311

G

tripartite motif-containing 25

decreases expression

avobenzone results in decreased expression of TRIM25 mRNA

NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257

G

tripartite motif-containing 69

decreases expression

avobenzone results in decreased expression of TRIM69 mRNA

NCBI chr 3:109,111,468...109,135,255
Ensembl chr 3:109,111,468...109,132,037

G

TSC22 domain family, member 3

increases expression

avobenzone results in increased expression of TSC22D3 mRNA

NCBI chr X:104,217,898...104,277,886
Ensembl chr X:104,217,925...104,276,861

G

tRNA splicing endonuclease subunit 2

decreases expression

avobenzone results in decreased expression of TSEN2 mRNA

NCBI chr 4:148,602,805...148,638,219
Ensembl chr 4:148,602,863...148,638,215

G

tetraspanin 1

increases expression

avobenzone results in increased expression of TSPAN1 mRNA

NCBI chr 5:129,646,139...129,659,383
Ensembl chr 5:129,646,993...129,652,017

G

TSPY-like 5

decreases expression

avobenzone results in decreased expression of TSPYL5 mRNA

NCBI chr 7:64,881,504...64,885,512
Ensembl chr 7:64,884,225...64,885,457

G

tau tubulin kinase 2

increases expression

avobenzone results in increased expression of TTBK2 mRNA

NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223

G

tetratricopeptide repeat domain 7B

increases expression

avobenzone results in increased expression of TTC7B mRNA

NCBI chr 6:119,587,389...119,799,167
Ensembl chr 6:119,587,390...119,799,330

G

tetratricopeptide repeat domain 9C

increases expression

avobenzone results in increased expression of TTC9C mRNA

NCBI chr 1:205,701,768...205,712,782
Ensembl chr 1:205,701,768...205,712,773

G

tubulin gamma complex component 3

increases expression

avobenzone results in increased expression of TUBGCP3 mRNA

NCBI chr16:76,851,859...76,912,499
Ensembl chr16:76,851,810...76,912,499

G

thioredoxin reductase 1

increases expression

avobenzone results in increased expression of TXNRD1 mRNA

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

thioredoxin reductase 2

increases expression

avobenzone results in increased expression of TXNRD2 mRNA

NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156

G

ubiquinol-cytochrome c reductase complex assembly factor 1

increases expression

avobenzone results in increased expression of UQCC1 mRNA

NCBI chr 3:144,353,276...144,445,810
Ensembl chr 3:144,353,287...144,445,711

G

ubiquitin specific peptidase 12

increases expression

avobenzone results in increased expression of USP12 mRNA

NCBI chr12:8,309,845...8,363,686
Ensembl chr12:8,309,750...8,363,656

G

vascular endothelial growth factor A

increases expression

avobenzone results in increased expression of VEGFA protein

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

WD repeat and HMG-box DNA binding protein 1

increases expression

avobenzone results in increased expression of WDHD1 mRNA

NCBI chr15:20,478,310...20,523,106
Ensembl chr15:20,489,291...20,523,096

G

WD repeat domain 5B

decreases expression

avobenzone results in decreased expression of WDR5B mRNA

NCBI chr11:64,710,945...64,712,804
Ensembl chr11:64,710,355...64,712,807

G

Wnt family member 9A

decreases expression

avobenzone results in decreased expression of WNT9A mRNA

NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133

G

XIAP associated factor 1

decreases expression

avobenzone results in decreased expression of XAF1 mRNA

NCBI chr10:56,917,378...56,929,791
Ensembl chr10:56,917,121...56,929,770

G

xanthine dehydrogenase

increases expression

avobenzone results in increased expression of XDH mRNA

NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268

G

X-linked Kx blood group antigen, Kell and VPS13A binding protein

decreases expression

avobenzone results in decreased expression of XK mRNA

NCBI chr X:13,436,412...13,472,830
Ensembl chr X:13,436,418...13,472,830

G

zinc finger, BED-type containing 3

decreases expression

avobenzone results in decreased expression of ZBED3 mRNA

NCBI chr 2:26,587,620...26,600,177
Ensembl chr 2:26,587,572...26,600,386

G

zinc finger and BTB domain containing 10

increases expression

avobenzone results in increased expression of ZBTB10 mRNA

NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515

G

zinc finger and BTB domain containing 44

increases expression

avobenzone results in increased expression of ZBTB44 mRNA

NCBI chr 8:29,466,055...29,524,027
Ensembl chr 8:29,466,352...29,518,163

G

zinc finger DHHC-type palmitoyltransferase 21

decreases expression

avobenzone results in decreased expression of ZDHHC21 mRNA

NCBI chr 5:97,227,621...97,286,866
Ensembl chr 5:97,229,345...97,286,537

G

zinc finger protein 112

decreases expression

avobenzone results in decreased expression of ZNF112 mRNA

NCBI chr 1:79,676,933...79,691,994
Ensembl chr 1:79,676,839...79,691,994

G

zinc finger protein 260

decreases expression

avobenzone results in decreased expression of ZNF260 mRNA

NCBI chr 1:85,336,567...85,349,896
Ensembl chr 1:85,336,618...85,350,067

G

zinc finger protein 418

decreases expression

avobenzone results in decreased expression of ZNF416 mRNA

NCBI chr 1:66,581,406...66,594,247
Ensembl chr 1:66,581,287...66,594,242

G

zinc finger protein 518B

decreases expression

avobenzone results in decreased expression of ZNF518B mRNA

NCBI chr14:72,121,085...72,140,479
Ensembl chr14:72,121,112...72,140,481

G

zinc finger protein 605

decreases expression

avobenzone results in decreased expression of ZNF605 mRNA

NCBI chr12:46,542,771...46,575,074
Ensembl chr12:46,545,073...46,575,828

G

zinc finger protein 606

decreases expression

avobenzone results in decreased expression of ZNF606 mRNA

NCBI chr 1:72,981,920...73,022,423
Ensembl chr 1:72,981,989...73,008,072

G

zinc finger protein 618

increases expression

avobenzone results in increased expression of ZNF618 mRNA

NCBI chr 5:76,398,514...76,564,837
Ensembl chr 5:76,398,366...76,564,834

G

zinc finger protein 623

decreases expression

avobenzone results in decreased expression of ZNF623 mRNA

NCBI chr 7:107,627,334...107,636,254
Ensembl chr 7:107,627,267...107,636,321

G

zinc finger protein 69

decreases expression

avobenzone results in decreased expression of ZFP69 mRNA

NCBI chr 5:134,502,002...134,516,428
Ensembl chr 5:134,501,998...134,514,358

G

zinc finger protein 74

increases expression

avobenzone results in increased expression of ZNF569 mRNA

NCBI chr 1:85,158,159...85,183,407
Ensembl chr 1:85,158,980...85,183,522

G

zinc finger protein 870

increases expression

avobenzone results in increased expression of ZNF670 mRNA

NCBI chr 7:11,990,146...12,003,813
Ensembl chr 7:11,990,148...12,003,813

G

zinc finger protein 879

decreases expression

avobenzone results in decreased expression of ZNF879 mRNA

NCBI chr10:35,148,679...35,158,674
Ensembl chr10:35,148,679...35,158,674

G

zinc finger protein 951

decreases expression

avobenzone results in decreased expression of ZNF844 mRNA

NCBI chr14:5,032,494...5,048,775
Ensembl chr14:5,033,734...5,048,756

G

zinc finger and SCAN domain containing 26

decreases expression

avobenzone results in decreased expression of ZSCAN26 mRNA

NCBI chr17:43,148,063...43,168,070
Ensembl chr17:43,148,079...43,168,070

G

zinc finger and SCAN domain containing 29, pseudogene 1

decreases expression

avobenzone results in decreased expression of ZSCAN29 mRNA

NCBI chr 3:108,136,468...108,140,431

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19831
chemical entity	19829
atom	19829
nonmetal atom	19767
oxygen atom	19509
oxygen molecular entity	19509
flavonoids	11609
dihydrochalcones	741
avobenzone	437
Path 2
Term	Annotations
CHEBI ontology	19831
subatomic particle	19829
composite particle	19829
hadron	19829
baryon	19829
nucleon	19829
atomic nucleus	19829
atom	19829
main group element atom	19779
p-block element atom	19779
carbon group element atom	19728
carbon atom	19724
organic molecular entity	19724
heteroorganic entity	19477
organochalcogen compound	19240
organooxygen compound	19155
carbonyl compound	18874
ketone	17181
aromatic ketone	12455
dihydrochalcones	741
avobenzone	437

paths to the root