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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tedisamil
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Accession:CHEBI:134747 term browser browse the term
Definition:A member of the class of diazabicyclononanes that is (1s,5s)-3,7-diazaspiro[bicyclo[3.3.1]nonane-9,1'-cyclopentane] in which the hydrogens at positions 3 and 7 are replaced by cyclopropylmethyl groups. It is a potassium channel blocker and an antiarrhythmic agent currently currently in development for the treatment of atrial fibrillation.
Synonyms:exact_synonym: (1s,5s)-3,7-bis(cyclopropylmethyl)-3,7-diazaspiro[bicyclo[3.3.1]nonane-9,1'-cyclopentane]
 related_synonym: Formula=C19H32N2;   InChI=1S/C19H32N2/c1-2-8-19(7-1)17-11-20(9-15-3-4-15)12-18(19)14-21(13-17)10-16-5-6-16/h15-18H,1-14H2/t17-,18+;   InChIKey=CTIRHWCPXYGDGF-HDICACEKSA-N;   KC-8857;   KC8857;   Pulzium;   SMILES=[H][C@]12CN(CC3CC3)C[C@]([H])(CN(CC3CC3)C1)C21CCCC1;   tedisamilum
 xref: CAS:90961-53-8;   DrugBank:DB06200;   Drug_Central:4655;   KEGG:D06652;   PMID:10566055;   PMID:10707827;   PMID:11116286;   PMID:11527020;   PMID:14996649;   PMID:15466442;   PMID:15579009;   PMID:1570027;   PMID:1769368;   PMID:19153714;   PMID:19299533;   PMID:19604120;   PMID:2017153;   PMID:2043919;   PMID:2721548;   PMID:2780585;   PMID:8480574;   PMID:8730401;   PMID:8882624;   PMID:9464363;   PMID:9831899;   Wikipedia:Tedisamil


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Term Annotations click to browse term
  CHEBI ontology 19767
    role 19714
      application 19403
        pharmaceutical 19303
          drug 19303
            cardiovascular drug 7667
              anti-arrhythmia drug 937
                tedisamil 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19767
    subatomic particle 19766
      composite particle 19766
        hadron 19766
          baryon 19766
            nucleon 19766
              atomic nucleus 19766
                atom 19766
                  main group element atom 19657
                    p-block element atom 19657
                      carbon group element atom 19573
                        carbon atom 19563
                          organic molecular entity 19563
                            organic molecule 19496
                              organic cyclic compound 19322
                                organic heterocyclic compound 18510
                                  organic heteropolycyclic compound 17978
                                    organic heterobicyclic compound 16785
                                      azabicycloalkane 1999
                                        diazabicyclononane 0
                                          tedisamil 0
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