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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:favipiravir
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Accession:CHEBI:134722 term browser browse the term
Definition:A member of the class of pyrazines that is pyrazine substituted by aminocarbonyl, hydroxy and fluoro groups at positions 2, 3 and 6, respectively. It is an anti-viral agent that inhibits RNA-dependent RNA polymerase of several RNA viruses and is approved for the treatment of influenza in Japan.
Synonyms:exact_synonym: 6-fluoro-3-hydroxypyrazine-2-carboxamide
 related_synonym: 6-fluoro-3-hydroxy-2-pyrazinecarboxamide;   Areplivir;   Avifavir;   Favilavir;   Favipira;   Formula=C5H4FN3O2;   InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11);   InChIKey=ZCGNOVWYSGBHAU-UHFFFAOYSA-N;   SMILES=NC(=O)C1=NC(F)=CN=C1O;   T-705;   T705;   avigan;   fapilavir;   favipiravirum
 xref: CAS:259793-96-9;   Chemspider:431002;   DrugBank:DB12466;   Drug_Central:4887;   KEGG:D09537
 xref_mesh: MESH:C462182
 xref: PMCID:PMC7971419;   PMID:28105854;   PMID:28324644;   PMID:28465146;   PMID:28769016;   PMID:29289664;   PMID:29289666;   PMID:29369776;   PMID:29765101;   PMID:29936152;   PMID:29982696;   PMID:30715325;   PMID:30951731;   PMID:31195019;   PMID:31507197;   PMID:31673977;   PMID:32174453;   PMID:32553844;   PMID:32645335;   PMID:32834770;   PMID:32836314;   PMID:32863356;   PMID:33108587;   PMID:33232871;   PMID:33268271;   PMID:33418497;   PMID:33451007;   PMID:33457366;   PMID:33478340;   PMID:33494498;   PMID:33526596;   PMID:33649117;   PMID:33859168;   Reaxys:9697246;   Wikipedia:Favipiravir


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favipiravir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Polg DNA polymerase gamma, catalytic subunit affects binding ISO favipiravir binds to POLG1 protein CTD PMID:36152797 NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      biological role 19785
        antimicrobial agent 18104
          antiviral agent 11061
            anticoronaviral agent 9656
              favipiravir 1
                favipiravir-RTP 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            heteroorganic entity 19459
                              organochalcogen compound 19222
                                organooxygen compound 19137
                                  carbon oxoacid 18597
                                    carboxylic acid 18594
                                      carboacyl group 17675
                                        univalent carboacyl group 17675
                                          carbamoyl group 17524
                                            carboxamide 17547
                                              primary carboxamide 5969
                                                favipiravir 1
                                                  favipiravir-RTP 0
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