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Accession:CHEBI:134609 term browser browse the term
Definition:A nitrosamine that is iminodiacetone that is substituted by a nitroso group at the N-atom. It induces pancreatic ductal adenocarcinomas in Syrian golden hamsters (other rodents are not susceptible).
Synonyms:exact_synonym: N,N-bis(2-oxopropyl)nitrous amide
 related_synonym: 2,2'-dioxo-di-n-propylnitrosamine;   2,2'-dioxopropyl-N-propylnitrosamine;   BOP;   Formula=C6H10N2O3;   InChI=1S/C6H10N2O3/c1-5(9)3-8(7-11)4-6(2)10/h3-4H2,1-2H3;   InChIKey=AKRYBBWYDSDZHG-UHFFFAOYSA-N;   N,N-di(2-oxopropyl)nitrosamine;   N-nitroso-N,N-di(2-oxypropyl)amine;   SMILES=N(N=O)(CC(C)=O)CC(C)=O;   bis-(2-oxopropyl)-N-nitrosamine
 xref: CAS:60599-38-4 "ChemIDplus"
 xref_mesh: MESH:C013622
 xref: PMID:17449904 "Europe PMC";   PMID:17510084 "Europe PMC";   PMID:18346132 "Europe PMC";   PMID:19846949 "Europe PMC";   PMID:21989024 "Europe PMC";   PMID:22225405 "Europe PMC";   PMID:22249130 "Europe PMC";   PMID:26354381 "Europe PMC";   PMID:26788138 "Europe PMC";   PMID:857032 "Europe PMC";   Reaxys:2245698 "Reaxys"

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nitrosobis(2-oxopropyl)amine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgb2 high mobility group box 2 JBrowse link 16 36,077,615 36,080,191 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19749
    role 19696
      biological role 19694
        aetiopathogenetic role 18797
          carcinogenic agent 17782
            nitrosobis(2-oxopropyl)amine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    p-block element atom 19630
                      carbon group element atom 19523
                        carbon atom 19517
                          organic molecular entity 19517
                            organic group 18427
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18305
                                    carbonyl compound 18305
                                      ketone 15922
                                        nitrosobis(2-oxopropyl)amine 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.