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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:diazepinoindole
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Accession:CHEBI:134605 term browser browse the term
Definition:Any organic heterotricyclic compound with a skeleton consisting of a diazepine ring fused to an indole.
Synonyms:related_synonym: diazepinoindoles



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PF-00477736 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO PF 00477736 inhibits the reaction [Mustard Gas results in increased phosphorylation of CDK1 protein] CTD PMID:25448276 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Chek1 checkpoint kinase 1 decreases activity
multiple interactions
ISO PF 00477736 results in decreased activity of CHEK1 protein
PF 00477736 inhibits the reaction [Mustard Gas results in increased phosphorylation of CHEK1 protein]
CTD PMID:21707865 PMID:25448276 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    chemical entity 20071
      atom 20071
        nonmetal atom 19963
          nitrogen atom 19043
            nitrogen molecular entity 19043
              organonitrogen compound 18842
                organonitrogen heterocyclic compound 17995
                  diazepinoindole 2
                    LY-2090314 0
                    PF-00477736 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19974
                    p-block element atom 19974
                      carbon group element atom 19903
                        carbon atom 19896
                          organic molecular entity 19896
                            organic molecule 19844
                              organic cyclic compound 19605
                                organic heterocyclic compound 18890
                                  organic heteropolycyclic compound 18300
                                    organic heterotricyclic compound 15623
                                      diazepinoindole 2
                                        LY-2090314 0
                                        PF-00477736 2
paths to the root