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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:diazepinoindole
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Accession:CHEBI:134605 term browser browse the term
Definition:Any organic heterotricyclic compound with a skeleton consisting of a diazepine ring fused to an indole.
Synonyms:related_synonym: diazepinoindoles


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PF-00477736 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO PF 00477736 inhibits the reaction [Mustard Gas results in increased phosphorylation of CDK1 protein] CTD PMID:25448276 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Chek1 checkpoint kinase 1 decreases activity
multiple interactions
ISO PF 00477736 results in decreased activity of CHEK1 protein
PF 00477736 inhibits the reaction [Mustard Gas results in increased phosphorylation of CHEK1 protein]
CTD PMID:21707865 PMID:25448276 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    chemical entity 19770
      atom 19768
        nonmetal atom 19651
          nitrogen atom 18582
            nitrogen molecular entity 18582
              organonitrogen compound 18370
                organonitrogen heterocyclic compound 17526
                  diazepinoindole 2
                    LY-2090314 0
                    PF-00477736 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19580
                        carbon atom 19571
                          organic molecular entity 19571
                            organic molecule 19504
                              organic cyclic compound 19331
                                organic heterocyclic compound 18519
                                  organic heteropolycyclic compound 17978
                                    organic heterotricyclic compound 14600
                                      diazepinoindole 2
                                        LY-2090314 0
                                        PF-00477736 2
paths to the root