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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:diazepinoindole
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Accession:CHEBI:134605 term browser browse the term
Definition:Any organic heterotricyclic compound with a skeleton consisting of a diazepine ring fused to an indole.
Synonyms:related_synonym: diazepinoindoles


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PF-00477736 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO PF 00477736 inhibits the reaction [Mustard Gas results in increased phosphorylation of CDK1 protein] CTD PMID:25448276 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Chek1 checkpoint kinase 1 decreases activity
multiple interactions		 ISO PF 00477736 results in decreased activity of CHEK1 protein
PF 00477736 inhibits the reaction [Mustard Gas results in increased phosphorylation of CHEK1 protein]		 CTD PMID:21707865 PMID:25448276 NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19900
    chemical entity 19898
      atom 19898
        nonmetal atom 19834
          nitrogen atom 18998
            nitrogen molecular entity 18998
              organonitrogen compound 18841
                organonitrogen heterocyclic compound 18177
                  diazepinoindole 2
                    LY-2090314 0
                    PF-00477736 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19900
    subatomic particle 19898
      composite particle 19898
        hadron 19898
          baryon 19898
            nucleon 19898
              atomic nucleus 19898
                atom 19898
                  main group element atom 19845
                    p-block element atom 19845
                      carbon group element atom 19792
                        carbon atom 19787
                          organic molecular entity 19787
                            organic molecule 19744
                              organic cyclic compound 19549
                                organic heterocyclic compound 18888
                                  organic heteropolycyclic compound 18315
                                    organic heterotricyclic compound 15646
                                      diazepinoindole 2
                                        LY-2090314 0
                                        PF-00477736 2
paths to the root