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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:omega-(methylthio)-2-oxocarboxylic acid
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Accession:CHEBI:134529 term browser browse the term
Definition:Any 2-oxo monocarboxylic acid in which one of the terminal methyl hydrogens has been replaced by a methylthio group.
Synonyms:related_synonym: omega-(methylthio)-2-oxocarboxylic acids
 cyclic_relationship: is_conjugate_acid_of CHEBI:133493


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4-methylthio-2-oxobutanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctbp2 C-terminal binding protein 2 decreases expression ISO 2-keto-4-methylthiobutyric acid results in decreased expression of CTBP2 protein CTD PMID:28414304 NCBI chr 1:187,782,064...187,918,115
Ensembl chr 1:187,782,682...187,920,222
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression ISO 2-keto-4-methylthiobutyric acid results in decreased expression of CTNNB1 protein CTD PMID:28414304 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Kyat1 kynurenine aminotransferase 1 affects metabolic processing EXP KYAT1 protein affects the metabolism of 2-keto-4-methylthiobutyric acid CTD PMID:2711386 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases activity ISO 2-keto-4-methylthiobutyric acid results in decreased activity of ODC1 protein CTD PMID:16870157 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    chemical entity 19812
      atom 19811
        nonmetal atom 19698
          sulfur atom 16395
            sulfur molecular entity 16395
              organosulfur compound 15272
                sulfur-containing carboxylic acid 5164
                  omega-(methylthio)-2-oxocarboxylic acid 4
                    4-methylthio-2-oxobutanoic acid + 4
                    5-methylthio-2-oxopentanoic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        monocarboxylic acid 17632
                                          oxo monocarboxylic acid 6273
                                            2-oxo monocarboxylic acid 59
                                              omega-(methylthio)-2-oxocarboxylic acid 4
                                                4-methylthio-2-oxobutanoic acid + 4
                                                5-methylthio-2-oxopentanoic acid 0
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