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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:13,14-dihydro-15-oxoprostaglandin E1
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Accession:CHEBI:134499 term browser browse the term
Definition:A prostaglandin E obtained by formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond of prostaglandin E1.
Synonyms:exact_synonym: (11alpha)-11-hydroxy-9,15-dioxoprostan-1-oic acid
 related_synonym: 13,14-Dihydro-15-keto-PGE1;   13,14-Dihydro-15-ketoprostaglandin E1;   13,14-dihydro-15-oxo-PGE1;   13,14-dihydro-15-oxo-prostaglandin E1;   Formula=C20H34O5;   InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h16-17,19,23H,2-14H2,1H3,(H,24,25)/t16-,17-,19-/m1/s1;   InChIKey=CDUVSQMTLOYKTR-ZHALLVOQSA-N;   SMILES=C(CCCCCC[C@H]1C(C[C@H]([C@@H]1CCC(CCCCC)=O)O)=O)(O)=O;   U 21002
 xref: CAS:5094-14-4
 xref_mesh: MESH:C036808
 xref: PMID:1589447;   PMID:1750222;   PMID:1793892;   PMID:1852896;   PMID:3244833;   PMID:6185792;   PMID:7904921;   PMID:8211888;   PMID:8581429;   PMID:871963;   PMID:9115911;   PMID:9174685;   PMID:9461497;   PMID:9653766;   Reaxys:3004655
 cyclic_relationship: is_conjugate_acid_of CHEBI:133408

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13,14-dihydro-15-oxoprostaglandin E1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgr1 prostaglandin reductase 1 increases abundance
multiple interactions
ISO PTGR1 protein results in increased abundance of 13,14-dihydro-15-ketoprostaglandin E1
[PTGR1 protein results in increased metabolism of 15-ketoprostaglandin E] which results in increased abundance of 13,14-dihydro-15-ketoprostaglandin E1
CTD PMID:25619643 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        biochemical role 19368
          metabolite 19344
            xenobiotic metabolite 14500
              human xenobiotic metabolite 13869
                13,14-dihydro-15-oxoprostaglandin E1 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        monocarboxylic acid 17622
                                          fatty acid 16011
                                            fatty acid derivative 1059
                                              icosanoid 462
                                                prostanoid 400
                                                  prostaglandin 395
                                                    prostaglandins E 234
                                                      prostaglandin E1 19
                                                        13,14-dihydro-15-oxoprostaglandin E1 1
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