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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:13,14-dihydro-15-oxoprostaglandin E1
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Accession:CHEBI:134499 term browser browse the term
Definition:A prostaglandin E obtained by formal oxidation of the 15-hydroxy group and hydrogenation of the 13,14-double bond of prostaglandin E1.
Synonyms:exact_synonym: (11alpha)-11-hydroxy-9,15-dioxoprostan-1-oic acid
 related_synonym: 13,14-Dihydro-15-keto-PGE1;   13,14-Dihydro-15-ketoprostaglandin E1;   13,14-dihydro-15-oxo-PGE1;   13,14-dihydro-15-oxo-prostaglandin E1;   Formula=C20H34O5;   InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h16-17,19,23H,2-14H2,1H3,(H,24,25)/t16-,17-,19-/m1/s1;   InChIKey=CDUVSQMTLOYKTR-ZHALLVOQSA-N;   SMILES=C(CCCCCC[C@H]1C(C[C@H]([C@@H]1CCC(CCCCC)=O)O)=O)(O)=O;   U 21002
 xref: CAS:5094-14-4
 xref_mesh: MESH:C036808
 xref: PMID:1589447;   PMID:1750222;   PMID:1793892;   PMID:1852896;   PMID:3244833;   PMID:6185792;   PMID:7904921;   PMID:8211888;   PMID:8581429;   PMID:871963;   PMID:9115911;   PMID:9174685;   PMID:9461497;   PMID:9653766;   Reaxys:3004655
 cyclic_relationship: is_conjugate_acid_of CHEBI:133408

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13,14-dihydro-15-oxoprostaglandin E1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgr1 prostaglandin reductase 1 increases abundance
multiple interactions
ISO PTGR1 protein results in increased abundance of 13,14-dihydro-15-ketoprostaglandin E1
[PTGR1 protein results in increased metabolism of 15-ketoprostaglandin E] which results in increased abundance of 13,14-dihydro-15-ketoprostaglandin E1
CTD PMID:25619643 NCBI chr 5:76,110,746...76,129,361
Ensembl chr 5:76,110,738...76,129,441
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            xenobiotic metabolite 14043
              human xenobiotic metabolite 13294
                13,14-dihydro-15-oxoprostaglandin E1 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        monocarboxylic acid 17407
                                          fatty acid 15845
                                            fatty acid derivative 1021
                                              icosanoid 453
                                                prostanoid 395
                                                  prostaglandin 390
                                                    prostaglandins E 233
                                                      prostaglandin E1 19
                                                        13,14-dihydro-15-oxoprostaglandin E1 1
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