Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-bromocarboxylic acid
go back to main search page
Accession:CHEBI:134367 term browser browse the term
Definition:Any carboxylic acid in which the carbon bearing the carboxy group is substituted by a bromine.
Synonyms:related_synonym: 2-bromocarboxylic acids;   Formula=C2H2BrO2R;   SMILES=OC(C(Br)*)=O;   alpha-bromocarboxylic acid;   alpha-bromocarboxylic acids


show annotations for term's descendants           Sort by:
 
2-bromohexadecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 decreases expression EXP 2-bromopalmitate results in decreased expression of APOA1 mRNA CTD PMID:7556148 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA] CTD PMID:30076181 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 2-bromopalmitate results in decreased expression of FAS mRNA CTD PMID:16712844 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases activity EXP 2-bromopalmitate results in increased activity of GAPDH protein CTD PMID:10650946 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA] CTD PMID:30076181 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IRF1 mRNA] CTD PMID:30076181 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Lat2 linker for activation of T cells family, member 2 decreases expression ISO 2-bromopalmitate results in decreased expression of LAT2 protein CTD PMID:23001822 NCBI chr12:25,114,099...25,128,381
Ensembl chr12:25,119,355...25,125,749
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO 2-bromopalmitate results in increased expression of LDLR mRNA CTD PMID:23150725 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lrat lecithin retinol acyltransferase increases expression EXP 2-bromopalmitate results in increased expression of LRAT mRNA CTD PMID:12576510 NCBI chr 2:181,896,304...181,905,366
Ensembl chr 2:181,896,305...181,905,300
JBrowse link
G Ly6e lymphocyte antigen 6 family member E multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of LY6E mRNA] CTD PMID:30076181 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in decreased expression of MPO mRNA] CTD PMID:30076181 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases activity
multiple interactions
ISO 2-bromopalmitate results in increased activity of PPARD protein
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]
CTD PMID:15997096, PMID:21543282, PMID:23150725 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP 2-bromopalmitate results in increased expression of PPARG protein CTD PMID:10650946 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO 2-bromopalmitate binds to and results in increased expression of RARA protein; 2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; 2-bromopalmitate inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; [2-bromopalmitate results in increased susceptibility to Tretinoin] which results in increased expression of RARA protein CTD PMID:30076181 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of RARB mRNA] CTD PMID:30076181 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599
JBrowse link
G Rbp1 retinol binding protein 1 increases expression EXP 2-bromopalmitate results in increased expression of RBP1 mRNA CTD PMID:12576510 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein] CTD PMID:15997096 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Spi1 Spi-1 proto-oncogene multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of SPI1 mRNA] CTD PMID:30076181 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA] CTD PMID:30076181 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP 2-bromopalmitate results in increased expression of UCP2 mRNA CTD PMID:11341955 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744
JBrowse link
bromochloroacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta increases expression ISO bromochloroacetic acid results in increased expression of ACTB protein CTD PMID:21296659 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression EXP bromochloroacetic acid results in decreased expression of ACTG2 mRNA CTD PMID:16460773 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP bromochloroacetic acid results in decreased expression of ACTN1 mRNA CTD PMID:16460773 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn4 actinin alpha 4 decreases expression EXP bromochloroacetic acid results in decreased expression of ACTN4 mRNA CTD PMID:16460773 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Afp alpha-fetoprotein decreases expression ISO bromochloroacetic acid results in decreased expression of AFP protein CTD PMID:21296659 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression EXP bromochloroacetic acid results in increased expression of AKT2 mRNA CTD PMID:16460773 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Arf4 ADP-ribosylation factor 4 decreases expression EXP bromochloroacetic acid results in decreased expression of ARF4 mRNA CTD PMID:16460773 NCBI chr16:2,338,333...2,354,909
Ensembl chr16:2,338,333...2,354,909
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression EXP bromochloroacetic acid results in increased expression of BNIP3L mRNA CTD PMID:16460773 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Ccn3 cellular communication network factor 3 decreases expression EXP bromochloroacetic acid results in decreased expression of CCN3 mRNA CTD PMID:16460773 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Cd34 CD34 molecule decreases expression ISO bromochloroacetic acid results in decreased expression of CD34 protein CTD PMID:21296659 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression EXP bromochloroacetic acid results in decreased expression of CDKN1A mRNA CTD PMID:16460773 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdx2 caudal type homeo box 2 increases expression ISO bromochloroacetic acid results in increased expression of CDX2 protein CTD PMID:21296659 NCBI chr12:9,464,026...9,470,565
Ensembl chr12:9,464,026...9,470,565
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO bromochloroacetic acid results in decreased expression of COL1A1 protein CTD PMID:21296659 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP bromochloroacetic acid results in decreased expression of COL1A2 mRNA CTD PMID:16460773 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO bromochloroacetic acid results in decreased expression of COL2A1 protein CTD PMID:21296659 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO bromochloroacetic acid results in increased expression of CRABP2 protein CTD PMID:21296659 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Ddx4 DEAD-box helicase 4 decreases expression ISO bromochloroacetic acid results in decreased expression of DDX4 protein CTD PMID:21296659 NCBI chr 2:44,447,610...44,504,263
Ensembl chr 2:44,447,573...44,504,354
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO bromochloroacetic acid results in decreased expression of DNMT3B protein CTD PMID:21296659 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO bromochloroacetic acid results in increased expression of EEF1A1 protein CTD PMID:21296659 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eomes eomesodermin decreases expression ISO bromochloroacetic acid results in decreased expression of EOMES protein CTD PMID:21296659 NCBI chr 8:127,144,367...127,152,618
Ensembl chr 8:127,144,903...127,151,493
JBrowse link
G Eras ES cell expressed Ras increases expression ISO bromochloroacetic acid results in increased expression of ERAS protein CTD PMID:21296659 NCBI chr  X:15,318,215...15,322,601
Ensembl chr  X:15,419,028...15,423,414
Ensembl chr  X:15,419,028...15,423,414
JBrowse link
G Fas Fas cell surface death receptor decreases expression EXP bromochloroacetic acid results in decreased expression of FAS mRNA CTD PMID:16460773 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fat1 FAT atypical cadherin 1 decreases expression EXP bromochloroacetic acid results in decreased expression of FAT1 mRNA CTD PMID:16460773 NCBI chr16:50,372,150...50,501,716
Ensembl chr16:50,372,128...50,501,921
JBrowse link
G Fgf4 fibroblast growth factor 4 increases expression ISO bromochloroacetic acid results in increased expression of FGF4 protein CTD PMID:21296659 NCBI chr 1:218,024,537...218,029,539
Ensembl chr 1:218,025,810...218,027,220
JBrowse link
G Fgf5 fibroblast growth factor 5 increases expression ISO bromochloroacetic acid results in increased expression of FGF5 protein CTD PMID:21296659 NCBI chr14:12,974,921...12,996,046
Ensembl chr14:12,974,921...12,995,584
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO bromochloroacetic acid results in decreased expression of FLT1 protein CTD PMID:21296659 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fn1 fibronectin 1 increases expression ISO bromochloroacetic acid results in increased expression of FN1 protein CTD PMID:21296659 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP bromochloroacetic acid results in decreased expression of FOS mRNA CTD PMID:16460773 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit decreases expression EXP bromochloroacetic acid results in decreased expression of FOSL1 mRNA CTD PMID:16460773 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Foxa2 forkhead box A2 affects expression ISO bromochloroacetic acid affects the expression of FOXA2 protein CTD PMID:21296659 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Fzd2 frizzled class receptor 2 decreases expression EXP bromochloroacetic acid results in decreased expression of FZD2 mRNA CTD PMID:16460773 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 affects expression ISO bromochloroacetic acid affects the expression of GABRB3 protein CTD PMID:21296659 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression EXP bromochloroacetic acid results in decreased expression of GADD45A mRNA CTD PMID:16460773 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression ISO bromochloroacetic acid results in increased expression of GAL protein CTD PMID:21296659 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO bromochloroacetic acid results in increased expression of GAPDH protein CTD PMID:21296659 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO bromochloroacetic acid results in increased expression of GATA6 protein CTD PMID:21296659 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Gbx2 gastrulation brain homeobox 2 increases expression ISO bromochloroacetic acid results in increased expression of GBX2 protein CTD PMID:21296659 NCBI chr 9:97,063,265...97,065,855
Ensembl chr 9:97,063,728...97,065,817
JBrowse link
G Gcm1 glial cells missing transcription factor 1 increases expression ISO bromochloroacetic acid results in increased expression of GCM1 protein CTD PMID:21296659 NCBI chr 8:85,355,766...85,369,002
Ensembl chr 8:85,355,766...85,369,002
JBrowse link
G Gdf3 growth differentiation factor 3 increases expression ISO bromochloroacetic acid results in increased expression of GDF3 protein CTD PMID:21296659 NCBI chr 4:155,417,667...155,422,014
Ensembl chr 4:155,417,004...155,421,998
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO bromochloroacetic acid results in decreased expression of GFAP protein CTD PMID:21296659 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gnaq G protein subunit alpha q decreases expression EXP bromochloroacetic acid results in decreased expression of GNAQ mRNA CTD PMID:16460773 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
G Grb7 growth factor receptor bound protein 7 increases expression ISO bromochloroacetic acid results in increased expression of GRB7 protein CTD PMID:21296659 NCBI chr10:86,393,186...86,408,893
Ensembl chr10:86,399,827...86,409,348
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects expression EXP bromochloroacetic acid affects the expression of GSK3B mRNA CTD PMID:16460773 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Hbz hemoglobin subunit zeta increases expression ISO bromochloroacetic acid results in increased expression of HBZ protein CTD PMID:21296659 NCBI chr10:15,609,348...15,610,826
Ensembl chr10:15,609,358...15,610,826
JBrowse link
G Iapp islet amyloid polypeptide decreases expression ISO bromochloroacetic acid results in decreased expression of IAPP protein CTD PMID:21296659 NCBI chr 4:176,509,863...176,517,903
Ensembl chr 4:176,510,696...176,516,083
JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 increases expression ISO bromochloroacetic acid results in increased expression of IFITM1 protein CTD PMID:21296659 NCBI chr 1:213,765,825...213,767,841
Ensembl chr 1:213,766,758...213,767,815
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 decreases expression ISO bromochloroacetic acid results in decreased expression of IFITM2 protein CTD PMID:21296659 NCBI chr 1:213,750,219...213,751,399
Ensembl chr 1:213,750,192...213,751,405
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP bromochloroacetic acid results in increased expression of IGF1 mRNA CTD PMID:16460773 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression EXP
ISO
bromochloroacetic acid results in increased expression of IGFBP2 mRNA
bromochloroacetic acid results in increased expression of IGFBP2 protein
CTD PMID:16460773, PMID:21296659 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression EXP bromochloroacetic acid results in increased expression of IGFBP3 mRNA CTD PMID:16460773 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 increases expression EXP bromochloroacetic acid results in increased expression of IGFBP6 mRNA CTD PMID:16460773 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
JBrowse link
G Il6st interleukin 6 signal transducer increases expression ISO bromochloroacetic acid results in increased expression of IL6ST protein CTD PMID:21296659 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Ilk integrin-linked kinase decreases expression EXP bromochloroacetic acid results in decreased expression of ILK mRNA CTD PMID:16460773 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Ins2 insulin 2 decreases expression ISO bromochloroacetic acid results in decreased expression of INS2 protein CTD PMID:21296659 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Itga8 integrin subunit alpha 8 decreases expression EXP bromochloroacetic acid results in decreased expression of ITGA8 mRNA CTD PMID:16460773 NCBI chr17:79,321,893...79,676,927
Ensembl chr17:79,321,900...79,676,499
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression EXP bromochloroacetic acid results in decreased expression of ITGB1 mRNA CTD PMID:16460773 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb2 integrin subunit beta 2 increases expression EXP bromochloroacetic acid results in increased expression of ITGB2 mRNA CTD PMID:16460773 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression ISO bromochloroacetic acid results in decreased expression of KIT protein CTD PMID:21296659 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Krt1 keratin 1 decreases expression ISO bromochloroacetic acid results in decreased expression of KRT1 protein CTD PMID:21296659 NCBI chr 7:143,448,318...143,453,544
Ensembl chr 7:143,448,318...143,453,544
JBrowse link
G Lama1 laminin subunit alpha 1 increases expression ISO bromochloroacetic acid results in increased expression of LAMA1 protein CTD PMID:21296659 NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
JBrowse link
G Lamb1 laminin subunit beta 1 decreases expression ISO bromochloroacetic acid results in decreased expression of LAMB1 protein CTD PMID:21296659 NCBI chr 6:50,528,796...50,596,593
Ensembl chr 6:50,528,823...50,596,079
JBrowse link
G Lamc1 laminin subunit gamma 1 increases expression ISO bromochloroacetic acid results in increased expression of LAMC1 protein CTD PMID:21296659 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515
JBrowse link
G Lefty1 left right determination factor 1 affects expression ISO bromochloroacetic acid affects the expression of LEFTY1 protein CTD PMID:21296659 NCBI chr13:99,212,778...99,217,786
Ensembl chr13:99,214,389...99,217,786
JBrowse link
G Lifr LIF receptor subunit alpha increases expression ISO bromochloroacetic acid results in increased expression of LIFR protein CTD PMID:21296659 NCBI chr 2:56,424,910...56,489,346
Ensembl chr 2:56,426,367...56,489,415
JBrowse link
G Lin28a lin-28 homolog A decreases expression ISO bromochloroacetic acid results in decreased expression of LIN28A protein CTD PMID:21296659 NCBI chr 5:152,230,343...152,247,873
Ensembl chr 5:152,230,343...152,247,332
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression EXP bromochloroacetic acid results in increased expression of MAPKAPK2 mRNA CTD PMID:16460773 NCBI chr13:47,785,157...47,871,684
Ensembl chr13:47,785,161...47,831,110
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 decreases expression ISO bromochloroacetic acid results in decreased expression of MNX1 protein CTD PMID:21296659 NCBI chr 4:2,376,350...2,381,308
Ensembl chr 4:2,376,958...2,381,271
JBrowse link
G Msln mesothelin increases expression EXP bromochloroacetic acid results in increased expression of MSLN mRNA CTD PMID:16460773 NCBI chr10:15,119,700...15,129,129
Ensembl chr10:15,119,663...15,125,408
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP bromochloroacetic acid results in increased expression of MYC mRNA CTD PMID:16460773 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myf5 myogenic factor 5 decreases expression ISO bromochloroacetic acid results in decreased expression of MYF5 protein CTD PMID:21296659 NCBI chr 7:49,729,533...49,732,974
Ensembl chr 7:49,729,533...49,732,764
JBrowse link
G Myod1 myogenic differentiation 1 decreases expression ISO bromochloroacetic acid results in decreased expression of MYOD1 protein CTD PMID:21296659 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248
JBrowse link
G Nanog Nanog homeobox increases expression ISO bromochloroacetic acid results in increased expression of NANOG protein CTD PMID:21296659 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Neurod1 neuronal differentiation 1 increases expression ISO bromochloroacetic acid results in increased expression of NEUROD1 protein CTD PMID:21296659 NCBI chr 3:66,414,314...66,417,617
Ensembl chr 3:66,414,308...66,417,741
JBrowse link
G Nodal nodal growth differentiation factor affects expression ISO bromochloroacetic acid affects the expression of NODAL protein CTD PMID:21296659 NCBI chr20:31,035,729...31,044,096
Ensembl chr20:31,035,729...31,044,096
JBrowse link
G Nog noggin increases expression ISO bromochloroacetic acid results in increased expression of NOG protein CTD PMID:21296659 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Nppa natriuretic peptide A increases expression ISO bromochloroacetic acid results in increased expression of NPPA protein CTD PMID:21296659 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO bromochloroacetic acid results in increased expression of NR5A2 protein CTD PMID:21296659 NCBI chr13:53,750,470...53,870,288
Ensembl chr13:53,750,473...53,870,428
JBrowse link
G Nras NRAS proto-oncogene, GTPase increases expression EXP bromochloroacetic acid results in increased expression of NRAS mRNA CTD PMID:16460773 NCBI chr 2:205,553,119...205,563,716
Ensembl chr 2:205,553,163...205,560,791
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 decreases expression ISO bromochloroacetic acid results in decreased expression of OLIG2 protein CTD PMID:21296659 NCBI chr11:31,389,514...31,392,890
Ensembl chr11:31,389,514...31,392,890
JBrowse link
G Pax6 paired box 6 increases expression ISO bromochloroacetic acid results in increased expression of PAX6 protein CTD PMID:21296659 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 decreases expression ISO bromochloroacetic acid results in decreased expression of IPF1 protein CTD PMID:21296659 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Podxl podocalyxin-like increases expression ISO bromochloroacetic acid results in increased expression of PODXL protein CTD PMID:21296659 NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO bromochloroacetic acid results in increased expression of POU5F1 protein CTD PMID:21296659 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A decreases expression EXP bromochloroacetic acid results in decreased expression of PPP1R12A mRNA CTD PMID:16460773 NCBI chr 7:51,404,971...51,515,382
Ensembl chr 7:51,404,919...51,515,373
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta increases expression EXP bromochloroacetic acid results in increased expression of PPP2R2B mRNA CTD PMID:16460773 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP bromochloroacetic acid results in increased expression of PRKCZ mRNA CTD PMID:16460773 NCBI chr 5:172,658,071...172,769,492
Ensembl chr 5:172,658,748...172,769,421
JBrowse link
G Rala RAS like proto-oncogene A decreases expression EXP bromochloroacetic acid results in decreased expression of RALA mRNA CTD PMID:16460773 NCBI chr17:49,676,073...49,729,133
Ensembl chr17:49,714,294...49,727,664
JBrowse link
G Rest RE1-silencing transcription factor decreases expression ISO bromochloroacetic acid results in decreased expression of REST protein CTD PMID:21296659 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
G Sema3a semaphorin 3A decreases expression ISO bromochloroacetic acid results in decreased expression of SEMA3A protein CTD PMID:21296659 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression ISO bromochloroacetic acid results in decreased expression of SFRP2 protein CTD PMID:21296659 NCBI chr 2:182,723,732...182,731,277
Ensembl chr 2:182,723,854...182,731,764
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases expression ISO bromochloroacetic acid results in decreased expression of SOX17 protein CTD PMID:21296659 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Sox2 SRY-box transcription factor 2 affects expression ISO bromochloroacetic acid affects the expression of SOX2 protein CTD PMID:21296659 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Sst somatostatin increases expression ISO bromochloroacetic acid results in increased expression of SST protein CTD PMID:21296659 NCBI chr11:80,358,172...80,359,449
Ensembl chr11:80,358,211...80,359,444
JBrowse link
G Sycp3 synaptonemal complex protein 3 decreases expression ISO bromochloroacetic acid results in decreased expression of SYCP3 protein CTD PMID:21296659 NCBI chr 7:29,029,887...29,044,344
Ensembl chr 7:29,029,263...29,044,251
JBrowse link
G Syp synaptophysin decreases expression ISO bromochloroacetic acid results in decreased expression of SYP protein CTD PMID:21296659 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Tat tyrosine aminotransferase decreases expression ISO bromochloroacetic acid results in decreased expression of TAT protein CTD PMID:21296659 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tbxt T-box transcription factor T increases expression ISO bromochloroacetic acid results in increased expression of T protein CTD PMID:21296659 NCBI chr 1:52,887,067...52,900,691
Ensembl chr 1:52,887,067...52,894,832
JBrowse link
G Tdgf1 teratocarcinoma-derived growth factor 1 increases expression ISO bromochloroacetic acid results in increased expression of TDGF1 protein CTD PMID:21296659 NCBI chr 8:119,215,266...119,220,909
Ensembl chr 8:119,215,495...119,219,232
JBrowse link
G Tert telomerase reverse transcriptase increases expression ISO bromochloroacetic acid results in increased expression of TERT protein CTD PMID:21296659 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression EXP bromochloroacetic acid results in decreased expression of TGFB2 mRNA CTD PMID:16460773 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 decreases expression EXP bromochloroacetic acid results in decreased expression of TGFB3 mRNA CTD PMID:16460773 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 increases expression EXP bromochloroacetic acid results in increased expression of TGFBR2 mRNA CTD PMID:16460773 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Th tyrosine hydroxylase affects expression ISO bromochloroacetic acid affects the expression of TH protein CTD PMID:21296659 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP bromochloroacetic acid promotes the reaction [Bromates results in increased phosphorylation of TP53 protein] CTD PMID:21864635 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Utf1 undifferentiated embryonic cell transcription factor 1 affects expression ISO bromochloroacetic acid affects the expression of UTF1 protein CTD PMID:21296659 NCBI chr 1:212,281,237...212,282,363
Ensembl chr 1:212,281,237...212,282,363
JBrowse link
G Wnt4 Wnt family member 4 increases expression EXP bromochloroacetic acid results in increased expression of WNT4 mRNA CTD PMID:16460773 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
G Wt1 WT1 transcription factor decreases expression ISO bromochloroacetic acid results in decreased expression of WT1 protein CTD PMID:21296659 NCBI chr 3:95,133,221...95,180,574
Ensembl chr 3:95,133,713...95,180,564
JBrowse link
G Zfp42 zinc finger protein 42 increases expression ISO bromochloroacetic acid results in increased expression of ZFP42 protein CTD PMID:21296659 NCBI chr16:52,016,590...52,026,346 JBrowse link
dibromoacetic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 increases expression ISO dibromoacetic acid results in increased expression of ATF2 mRNA CTD PMID:29155130 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO dibromoacetic acid results in decreased expression of BCL2 mRNA CTD PMID:18628252 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases expression ISO dibromoacetic acid results in increased expression of CASP3 protein modified form CTD PMID:29155130 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ces3a carboxylesterase 3a decreases expression EXP dibromoacetic acid results in decreased expression of CES3 mRNA CTD PMID:21046364 NCBI chr19:37,070,705...37,079,411 JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression EXP dibromoacetic acid results in decreased expression of COL1A2 mRNA CTD PMID:21046364 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP17A1 mRNA CTD PMID:21046364 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases expression EXP dibromoacetic acid results in decreased expression of CYP1B1 mRNA CTD PMID:21046364 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Dpt dermatopontin decreases expression EXP dibromoacetic acid results in decreased expression of DPT mRNA CTD PMID:21046364 NCBI chr13:83,073,307...83,102,404
Ensembl chr13:83,073,544...83,102,401
JBrowse link
G Elk1 ETS transcription factor ELK1 increases expression ISO dibromoacetic acid results in increased expression of ELK1 mRNA CTD PMID:29155130 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP dibromoacetic acid inhibits the reaction [Estradiol binds to ESR1 protein] CTD PMID:10580743 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP dibromoacetic acid results in decreased expression of FADS1 mRNA CTD PMID:21046364 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO dibromoacetic acid results in increased expression of FAS mRNA; dibromoacetic acid results in increased expression of FAS protein CTD PMID:18628252 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression ISO dibromoacetic acid results in increased expression of FASL protein CTD PMID:18628252 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Hao2 hydroxyacid oxidase 2 decreases expression EXP dibromoacetic acid results in decreased expression of HAO2 mRNA CTD PMID:21046364 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP dibromoacetic acid results in decreased expression of HBA-A2 mRNA CTD PMID:21046364 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP dibromoacetic acid results in decreased expression of HBB mRNA CTD PMID:21046364 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression EXP dibromoacetic acid results in decreased expression of IGFBP7 mRNA CTD PMID:21046364 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Insl3 insulin-like 3 decreases expression EXP dibromoacetic acid results in decreased expression of INSL3 mRNA CTD PMID:21046364 NCBI chr16:20,120,753...20,122,702
Ensembl chr16:20,121,352...20,122,696
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases methylation ISO dibromoacetic acid results in decreased methylation of MYC promoter CTD PMID:16014735 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Traf2 Tnf receptor-associated factor 2 increases expression ISO dibromoacetic acid results in increased expression of TRAF2 mRNA CTD PMID:18628252 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      chemical role 19288
        donor 18421
          Bronsted acid 18289
            oxoacid 18241
              carbon oxoacid 18126
                carboxylic acid 18114
                  2-bromocarboxylic acid 143
                    2-bromodecanoic acid 0
                    2-bromohexadecanoic acid 20
                    bromochloroacetic acid 108
                    bromosuccinic acid 0
                    dibromoacetic acid 20
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        2-bromocarboxylic acid 143
                                          2-bromodecanoic acid 0
                                          2-bromohexadecanoic acid 20
                                          bromochloroacetic acid 108
                                          bromosuccinic acid 0
                                          dibromoacetic acid 20
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.