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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:homoallylic alcohol
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Accession:CHEBI:134362 term browser browse the term
Definition:An aliphatic alcohol where the hydroxy carbon is beta to a double bond.
Synonyms:related_synonym: Formula=C4HOR7;   SMILES=C(=C(*)*)(C(C(O)(*)*)(*)*)*;   homoallylic alcohols


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(+)-trans-(S)-allethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO bioallethrin results in decreased activity of ACE protein CTD PMID:32097678 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Cat catalase decreases activity ISO bioallethrin results in decreased activity of CAT protein CTD PMID:32097678 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ces1d carboxylesterase 1D increases metabolic processing ISO CES1 protein results in increased metabolism of bioallethrin CTD PMID:19249324 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO [DDT co-treated with bioallethrin] results in increased expression of CHRM4 mRNA CTD PMID:10192214 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
increases expression
ISO CYP3A4 protein results in increased metabolism of bioallethrin
bioallethrin results in increased expression of CYP3A4 mRNA
CTD PMID:19249324 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Glo1 glyoxalase 1 increases activity ISO bioallethrin results in increased activity of GLO1 protein CTD PMID:32097678 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO bioallethrin results in decreased activity of GSR protein CTD PMID:32097678 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
affects expression
ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IFNG protein
bioallethrin results in decreased expression of IFNG mRNA
bioallethrin affects the expression of IFNG protein
CTD PMID:9860237 PMID:10414782 PMID:12755381 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il4 interleukin 4 multiple interactions
affects expression
ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IL4 protein
bioallethrin affects the expression of IL4 protein
CTD PMID:9860237 PMID:10414782 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO
EXP
bioallethrin results in increased activity of NR1I2 protein CTD PMID:19249324 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 affects activity EXP bioallethrin affects the activity of SCN10A protein CTD PMID:19766671 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 1:86,353,917...86,363,836
Ensembl chr 1:86,353,917...86,363,739
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 7:131,982,152...132,156,075
Ensembl chr 7:131,982,480...132,151,292
JBrowse link
(Z)-hex-3-en-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pomc proopiomelanocortin multiple interactions EXP [2,5-dihydro-2,4,5-trimethylthiazoline co-treated with 3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC protein; [3-hexen-1-ol co-treated with 2-hexenal] inhibits the reaction [2,5-dihydro-2,4,5-trimethylthiazoline results in decreased expression of POMC protein]; [3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC CTD PMID:19103229 PMID:21515296 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
castor oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases expression
multiple interactions
EXP Castor Oil results in increased expression of PAFAH1B1 protein
isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein]
CTD PMID:1354728 PMID:2743081 PMID:8738301 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
JBrowse link
drimenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO drimenol results in increased expression of BAX protein CTD PMID:30935903 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO drimenol results in decreased expression of BCL2 protein CTD PMID:30935903 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 increases activity ISO drimenol results in increased activity of CASP3 protein CTD PMID:30935903 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases cleavage ISO drimenol results in increased cleavage of CASP9 protein CTD PMID:30935903 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
imiprothrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases expression EXP imiprothrin results in decreased expression of CAT protein CTD PMID:33638779 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP imiprothrin results in increased expression of CYP1A2 mRNA CTD PMID:33638779 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP imiprothrin results in increased expression of GPT protein CTD PMID:33638779 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Mt1 metallothionein 1 increases expression EXP imiprothrin results in increased expression of MT1 mRNA CTD PMID:33638779 NCBI chr19:10,826,032...10,827,048 JBrowse link
pyrethrins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator affects expression ISO Pyrethrins affects the expression of BAX protein CTD PMID:27939866 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO Pyrethrins affects the expression of BCL2 protein CTD PMID:27939866 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Pyrethrins inhibits the reaction [Potassium results in increased expression of BDNF mRNA] CTD PMID:15527870 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Casp3 caspase 3 increases activity ISO Pyrethrins results in increased activity of CASP3 protein CTD PMID:27939866 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity ISO Pyrethrins results in increased activity of CASP9 protein CTD PMID:27939866 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Pyrethrins results in increased expression of CYP2B1 mRNA CTD PMID:18022748 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Pyrethrins results in increased expression of CYP2B2 mRNA CTD PMID:18022748 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Pyrethrins results in increased expression of CYP2B6 mRNA CTD PMID:18022748 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Pyrethrins results in increased expression of CYP3A4 mRNA CTD PMID:18022748 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Pyrethrins inhibits the reaction [Potassium results in increased expression of FOS mRNA] CTD PMID:15527870 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Pyrethrins binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Pyrethrins results in increased cleavage of PARP1 protein CTD PMID:27939866 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Pyrethrins binds to and results in increased activity of PPARA protein CTD PMID:17084873 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
ricinoleic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 affects binding ISO ricinoleic acid analog binds to CNR1 protein CTD PMID:16406364 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO ricinoleic acid analog binds to and affects the activity of CNR2 protein CTD PMID:16406364 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
JBrowse link
G Il4 interleukin 4 multiple interactions ISO ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] CTD PMID:7544037 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO ricinoleic acid binds to PTGDS protein CTD PMID:26456343 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO ricinoleic acid analog binds to and affects the activity of TRPV1 protein CTD PMID:16406364 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] CTD PMID:7544037 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    chemical entity 19812
      atom 19811
        nonmetal atom 19698
          carbon atom 19620
            organic molecular entity 19620
              olefinic compound 15500
                homoallylic alcohol 35
                  (+)-(2S,3R,9R)-pristinol 0
                  (+)-albicanol 0
                  (3Z,6Z,9Z)-dodecatrienol 0
                  (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
                  (9Z)-12-hydroxyoctadec-9-enoic acid + 7
                  (E)-3-decen-1-ol 0
                  10-epi-juneol 0
                  10-epi-pyriculol 0
                  12-hydroxyjasmonic acid + 0
                  2-methylene-1,4-butanediol 0
                  20-HEPE 0
                  2beta-hydroxy-5-epi-aristolochene 0
                  4-methylpent-3-en-1-ol + 0
                  5,20-diHEPE 0
                  5-(2-hydroxyethyl)isolongifol-4-ene 0
                  5-(2-hydroxyethyl)isolongifol-5-ene 0
                  6-hydroxyhex-3-enoic acid + 0
                  6-hydroxyhex-3-enoyl-CoA + 0
                  6-tuliposide A 0
                  Delta(12)-prostaglandin J3 0
                  N(5)-anhydromevalonyl-N(5)-hydroxy-L-ornithine 0
                  N-[(+)-12-hydroxy-7-isojasmonyl]isoleucine 0
                  N-[(3R)-12-hydroxyjasmonyl]-L-isoleucine 0
                  N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[5-hydroxy-3-(2-oxolanylmethyldisulfanyl)pent-2-en-2-yl]formamide 0
                  Thiamine disulfide 0
                  Tuliposide A 0
                  anhydromevalonyl-CoA 0
                  asperaculane G 0
                  chrysanthemol + 28
                  coprogen 0
                  coprogen B 0
                  desferricoprogen 0
                  desferricoprogen B 0
                  dihydropyriculariol 0
                  dihydropyriculol 0
                  drimendiol 0
                  drimenol + 4
                  eupatolide 0
                  ferrirubin 0
                  hex-3-en-1-ol + 1
                  isogeraniol + 0
                  isopentenyl alcohol + 0
                  marinolic acid C 0
                  methyl tuberonate 0
                  pyriculariol 0
                  pyriculol + 0
                  taxine B 0
                  triricinolein + 1
                  tuberonic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      chalcogen 19460
                        oxygen atom 19436
                          oxygen molecular entity 19436
                            hydroxides 19175
                              organic hydroxy compound 18668
                                alcohol 15081
                                  aliphatic alcohol 11325
                                    homoallylic alcohol 35
                                      (+)-(2S,3R,9R)-pristinol 0
                                      (+)-albicanol 0
                                      (3Z,6Z,9Z)-dodecatrienol 0
                                      (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
                                      (9Z)-12-hydroxyoctadec-9-enoic acid + 7
                                      (E)-3-decen-1-ol 0
                                      10-epi-juneol 0
                                      10-epi-pyriculol 0
                                      12-hydroxyjasmonic acid + 0
                                      2-methylene-1,4-butanediol 0
                                      20-HEPE 0
                                      2beta-hydroxy-5-epi-aristolochene 0
                                      4-methylpent-3-en-1-ol + 0
                                      5,20-diHEPE 0
                                      5-(2-hydroxyethyl)isolongifol-4-ene 0
                                      5-(2-hydroxyethyl)isolongifol-5-ene 0
                                      6-hydroxyhex-3-enoic acid + 0
                                      6-hydroxyhex-3-enoyl-CoA + 0
                                      6-tuliposide A 0
                                      Delta(12)-prostaglandin J3 0
                                      N(5)-anhydromevalonyl-N(5)-hydroxy-L-ornithine 0
                                      N-[(+)-12-hydroxy-7-isojasmonyl]isoleucine 0
                                      N-[(3R)-12-hydroxyjasmonyl]-L-isoleucine 0
                                      N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[5-hydroxy-3-(2-oxolanylmethyldisulfanyl)pent-2-en-2-yl]formamide 0
                                      Thiamine disulfide 0
                                      Tuliposide A 0
                                      anhydromevalonyl-CoA 0
                                      asperaculane G 0
                                      chrysanthemol + 28
                                      coprogen 0
                                      coprogen B 0
                                      desferricoprogen 0
                                      desferricoprogen B 0
                                      dihydropyriculariol 0
                                      dihydropyriculol 0
                                      drimendiol 0
                                      drimenol + 4
                                      eupatolide 0
                                      ferrirubin 0
                                      hex-3-en-1-ol + 1
                                      isogeraniol + 0
                                      isopentenyl alcohol + 0
                                      marinolic acid C 0
                                      methyl tuberonate 0
                                      pyriculariol 0
                                      pyriculol + 0
                                      taxine B 0
                                      triricinolein + 1
                                      tuberonic acid + 0
paths to the root