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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:homoallylic alcohol
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Accession:CHEBI:134362 term browser browse the term
Definition:An aliphatic alcohol where the hydroxy carbon is beta to a double bond.
Synonyms:related_synonym: Formula=C4HOR7;   SMILES=C(=C(*)*)(C(C(O)(*)*)(*)*)*;   homoallylic alcohols


show annotations for term's descendants           Sort by:
(+)-trans-(S)-allethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO bioallethrin results in decreased activity of ACE protein CTD PMID:32097678 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 ISO Vitamin E inhibits the reaction [bioallethrin results in increased expression of BAX protein] CTD PMID:35511042 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions		 ISO bioallethrin results in increased cleavage of CASP3 protein
Vitamin E inhibits the reaction [bioallethrin results in increased cleavage of CASP3 protein]		 CTD PMID:35511042 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage		 ISO Vitamin E inhibits the reaction [bioallethrin results in increased cleavage of CASP9 protein] CTD PMID:35511042 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases activity ISO bioallethrin results in decreased activity of CAT protein CTD PMID:32097678 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ces1d carboxylesterase 1D increases metabolic processing ISO CES1 protein results in increased metabolism of bioallethrin CTD PMID:19249324 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO [DDT co-treated with bioallethrin] results in increased expression of CHRM4 mRNA CTD PMID:10192214 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
increases expression		 ISO CYP3A4 protein results in increased metabolism of bioallethrin
bioallethrin results in increased expression of CYP3A4 mRNA		 CTD PMID:19249324 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Glo1 glyoxalase 1 increases activity ISO bioallethrin results in increased activity of GLO1 protein CTD PMID:32097678 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO bioallethrin results in decreased activity of GSR protein CTD PMID:32097678 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO bioallethrin results in increased expression of HMOX1 protein
[Vitamin E co-treated with bioallethrin] results in increased expression of HMOX1 protein		 CTD PMID:35511042 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
affects expression		 ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IFNG protein
bioallethrin results in decreased expression of IFNG mRNA
bioallethrin affects the expression of IFNG protein		 CTD PMID:9860237 PMID:10414782 PMID:12755381 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il4 interleukin 4 multiple interactions
affects expression		 ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IL4 protein
bioallethrin affects the expression of IL4 protein		 CTD PMID:9860237 PMID:10414782 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions		 ISO bioallethrin results in increased expression of NFE2L2 protein
Vitamin E inhibits the reaction [bioallethrin results in increased expression of NFE2L2 protein]		 CTD PMID:35511042 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions		 ISO bioallethrin results in increased expression of NQO1 protein
[Vitamin E co-treated with bioallethrin] results in increased expression of NQO1 protein		 CTD PMID:35511042 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO
EXP		 bioallethrin results in increased activity of NR1I2 protein CTD PMID:19249324 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 affects activity EXP bioallethrin affects the activity of SCN10A protein CTD PMID:19766671 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 1:86,353,917...86,363,836
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 8:45,425,629...45,437,765
Ensembl chr 8:45,425,629...45,437,765 		JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 7:131,982,152...132,156,075
Ensembl chr 7:131,982,480...132,151,292 		JBrowse link
(Z)-hex-3-en-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pomc proopiomelanocortin multiple interactions EXP [2,5-dihydro-2,4,5-trimethylthiazoline co-treated with 3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC protein; [3-hexen-1-ol co-treated with 2-hexenal] inhibits the reaction [2,5-dihydro-2,4,5-trimethylthiazoline results in decreased expression of POMC protein]; [3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC CTD PMID:19103229 PMID:21515296 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
castor oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases expression
multiple interactions		 EXP Castor Oil results in increased expression of PAFAH1B1 protein
isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein]		 CTD PMID:1354728 PMID:2743081 PMID:8738301 NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808 		JBrowse link
drimenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO drimenol results in increased expression of BAX protein CTD PMID:30935903 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO drimenol results in decreased expression of BCL2 protein CTD PMID:30935903 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity ISO drimenol results in increased activity of CASP3 protein CTD PMID:30935903 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases cleavage ISO drimenol results in increased cleavage of CASP9 protein CTD PMID:30935903 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
imiprothrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase decreases expression EXP imiprothrin results in decreased expression of CAT protein CTD PMID:33638779 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP imiprothrin results in increased expression of CYP1A2 mRNA CTD PMID:33638779 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP imiprothrin results in increased expression of GPT protein CTD PMID:33638779 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
pyrethrins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator affects expression ISO Pyrethrins affects the expression of BAX protein CTD PMID:27939866 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO Pyrethrins affects the expression of BCL2 protein CTD PMID:27939866 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Pyrethrins inhibits the reaction [Potassium results in increased expression of BDNF mRNA] CTD PMID:15527870 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Casp3 caspase 3 increases activity ISO Pyrethrins results in increased activity of CASP3 protein CTD PMID:27939866 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases activity ISO Pyrethrins results in increased activity of CASP9 protein CTD PMID:27939866 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase increases activity EXP Pyrethrins results in increased activity of CAT protein CTD PMID:35678313 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Pyrethrins results in increased expression of CYP2B1 mRNA CTD PMID:18022748 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Pyrethrins results in increased expression of CYP2B2 mRNA CTD PMID:18022748 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Pyrethrins results in increased expression of CYP2B6 mRNA CTD PMID:18022748 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression ISO Pyrethrins results in increased expression of CYP3A4 mRNA CTD PMID:18022748 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Pyrethrins inhibits the reaction [Potassium results in increased expression of FOS mRNA] CTD PMID:15527870 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gpt glutamic--pyruvic transaminase affects activity EXP Pyrethrins affects the activity of GPT protein CTD PMID:35678313 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Pyrethrins binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Pyrethrins results in increased cleavage of PARP1 protein CTD PMID:27939866 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Pyrethrins binds to and results in increased activity of PPARA protein CTD PMID:17084873 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
ricinoleic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 affects binding ISO ricinoleic acid analog binds to CNR1 protein CTD PMID:16406364 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO ricinoleic acid analog binds to and affects the activity of CNR2 protein CTD PMID:16406364 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] CTD PMID:7544037 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO ricinoleic acid binds to PTGDS protein CTD PMID:26456343 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO ricinoleic acid analog binds to and affects the activity of TRPV1 protein CTD PMID:16406364 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] CTD PMID:7544037 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    chemical entity 19810
      atom 19810
        nonmetal atom 19744
          carbon atom 19693
            organic molecular entity 19693
              olefinic compound 16903
                homoallylic alcohol 37
                  (+)-(2S,3R,9R)-pristinol 0
                  (+)-albicanol 0
                  (3Z,6Z,9Z)-dodecatrienol 0
                  (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
                  (9Z)-12-hydroxyoctadec-9-enoic acid + 7
                  (E)-3-decen-1-ol 0
                  10-epi-juneol 0
                  10-epi-pyriculol 0
                  12-hydroxyjasmonic acid + 0
                  2-methylene-1,4-butanediol 0
                  20-HEPE 0
                  2beta-hydroxy-5-epi-aristolochene 0
                  4-methylpent-3-en-1-ol + 0
                  5,20-diHEPE 0
                  5-(2-hydroxyethyl)isolongifol-4-ene 0
                  5-(2-hydroxyethyl)isolongifol-5-ene 0
                  6-hydroxyhex-3-enoic acid + 0
                  6-hydroxyhex-3-enoyl-CoA + 0
                  6-tuliposide A 0
                  Delta(12)-prostaglandin J3 0
                  N(5)-anhydromevalonyl-N(5)-hydroxy-L-ornithine 0
                  N-[(+)-12-hydroxy-7-isojasmonyl]isoleucine 0
                  N-[(3R)-12-hydroxyjasmonyl]-L-isoleucine 0
                  N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[5-hydroxy-3-(2-oxolanylmethyldisulfanyl)pent-2-en-2-yl]formamide 0
                  Thiamine disulfide 0
                  Tuliposide A 0
                  anhydromevalonyl-CoA 0
                  asperaculane G 0
                  chrysanthemol + 30
                  coprogen 0
                  coprogen B 0
                  desferricoprogen 0
                  desferricoprogen B 0
                  dihydropyriculariol 0
                  dihydropyriculol 0
                  diricinolein 0
                  drimendiol 0
                  drimenol + 4
                  eupatolide 0
                  ferrirubin 0
                  hex-3-en-1-ol + 1
                  isogeraniol + 0
                  isopentenyl alcohol + 0
                  marinolic acid C 0
                  methyl tuberonate 0
                  pyriculariol 0
                  pyriculol + 0
                  taxine B 0
                  triricinolein + 1
                  tuberonic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19810
      composite particle 19810
        hadron 19810
          baryon 19810
            nucleon 19810
              atomic nucleus 19810
                atom 19810
                  main group element atom 19755
                    p-block element atom 19755
                      chalcogen 19543
                        oxygen atom 19519
                          oxygen molecular entity 19519
                            hydroxides 19306
                              organic hydroxy compound 18930
                                alcohol 15191
                                  aliphatic alcohol 11394
                                    homoallylic alcohol 37
                                      (+)-(2S,3R,9R)-pristinol 0
                                      (+)-albicanol 0
                                      (3Z,6Z,9Z)-dodecatrienol 0
                                      (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
                                      (9Z)-12-hydroxyoctadec-9-enoic acid + 7
                                      (E)-3-decen-1-ol 0
                                      10-epi-juneol 0
                                      10-epi-pyriculol 0
                                      12-hydroxyjasmonic acid + 0
                                      2-methylene-1,4-butanediol 0
                                      20-HEPE 0
                                      2beta-hydroxy-5-epi-aristolochene 0
                                      4-methylpent-3-en-1-ol + 0
                                      5,20-diHEPE 0
                                      5-(2-hydroxyethyl)isolongifol-4-ene 0
                                      5-(2-hydroxyethyl)isolongifol-5-ene 0
                                      6-hydroxyhex-3-enoic acid + 0
                                      6-hydroxyhex-3-enoyl-CoA + 0
                                      6-tuliposide A 0
                                      Delta(12)-prostaglandin J3 0
                                      N(5)-anhydromevalonyl-N(5)-hydroxy-L-ornithine 0
                                      N-[(+)-12-hydroxy-7-isojasmonyl]isoleucine 0
                                      N-[(3R)-12-hydroxyjasmonyl]-L-isoleucine 0
                                      N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[5-hydroxy-3-(2-oxolanylmethyldisulfanyl)pent-2-en-2-yl]formamide 0
                                      Thiamine disulfide 0
                                      Tuliposide A 0
                                      anhydromevalonyl-CoA 0
                                      asperaculane G 0
                                      chrysanthemol + 30
                                      coprogen 0
                                      coprogen B 0
                                      desferricoprogen 0
                                      desferricoprogen B 0
                                      dihydropyriculariol 0
                                      dihydropyriculol 0
                                      diricinolein 0
                                      drimendiol 0
                                      drimenol + 4
                                      eupatolide 0
                                      ferrirubin 0
                                      hex-3-en-1-ol + 1
                                      isogeraniol + 0
                                      isopentenyl alcohol + 0
                                      marinolic acid C 0
                                      methyl tuberonate 0
                                      pyriculariol 0
                                      pyriculol + 0
                                      taxine B 0
                                      triricinolein + 1
                                      tuberonic acid + 0
paths to the root