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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:homoallylic alcohol
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Accession:CHEBI:134362 term browser browse the term
Definition:An aliphatic alcohol where the hydroxy carbon is beta to a double bond.
Synonyms:related_synonym: Formula=C4HOR7;   SMILES=C(=C(*)*)(C(C(O)(*)*)(*)*)*;   homoallylic alcohols


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(+)-trans-(S)-allethrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO bioallethrin results in decreased activity of ACE protein CTD PMID:32097678 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Cat catalase decreases activity ISO bioallethrin results in decreased activity of CAT protein CTD PMID:32097678 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ces1d carboxylesterase 1D increases metabolic processing ISO CES1 protein results in increased metabolism of bioallethrin CTD PMID:19249324 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO [DDT co-treated with bioallethrin] results in increased expression of CHRM4 mRNA CTD PMID:10192214 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Glo1 glyoxalase 1 increases activity ISO bioallethrin results in increased activity of GLO1 protein CTD PMID:32097678 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO bioallethrin results in decreased activity of GSR protein CTD PMID:32097678 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
affects expression
ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IFNG protein
bioallethrin results in decreased expression of IFNG mRNA
bioallethrin affects the expression of IFNG protein
CTD PMID:9860237, PMID:10414782, PMID:12755381 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il4 interleukin 4 multiple interactions
affects expression
ISO [bioallethrin co-treated with Piperonyl Butoxide] results in increased expression of IL4 protein
bioallethrin affects the expression of IL4 protein
CTD PMID:9860237, PMID:10414782 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO
EXP
bioallethrin results in increased activity of NR1I2 protein CTD PMID:19249324 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 affects activity EXP bioallethrin affects the activity of SCN10A protein CTD PMID:19766671 NCBI chr 8:128,298,593...128,416,896
Ensembl chr 8:128,298,594...128,416,650
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 8:49,419,003...49,431,110
Ensembl chr 8:49,418,965...49,427,689
JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 multiple interactions EXP bioallethrin affects the reaction [[SCN2B protein co-treated with SCN1B protein co-treated with SCN8A protein mutant form] results in increased transport of Sodium] CTD PMID:22465659 NCBI chr 7:142,575,629...142,683,659
Ensembl chr 7:142,575,672...142,684,114
JBrowse link
(Z)-hex-3-en-1-ol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pomc proopiomelanocortin multiple interactions EXP [2,5-dihydro-2,4,5-trimethylthiazoline co-treated with 3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC protein; [3-hexen-1-ol co-treated with 2-hexenal] inhibits the reaction [2,5-dihydro-2,4,5-trimethylthiazoline results in decreased expression of POMC protein]; [3-hexen-1-ol co-treated with 2-hexenal] results in decreased expression of POMC CTD PMID:19103229, PMID:21515296 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
castor oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases expression
multiple interactions
EXP Castor Oil results in increased expression of PAFAH1B1 protein
isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein]
CTD PMID:1354728, PMID:2743081, PMID:8738301 NCBI chr10:61,456,144...61,577,412
Ensembl chr10:61,456,145...61,577,412
JBrowse link
drimenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator increases expression ISO drimenol results in increased expression of BAX protein CTD PMID:30935903 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO drimenol results in decreased expression of BCL2 protein CTD PMID:30935903 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 increases activity ISO drimenol results in increased activity of CASP3 protein CTD PMID:30935903 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases cleavage ISO drimenol results in increased cleavage of CASP9 protein CTD PMID:30935903 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
pyrethrins term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator affects expression ISO Pyrethrins affects the expression of BAX protein CTD PMID:27939866 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression ISO Pyrethrins affects the expression of BCL2 protein CTD PMID:27939866 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO Pyrethrins inhibits the reaction [Potassium results in increased expression of BDNF mRNA] CTD PMID:15527870 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Casp3 caspase 3 increases activity ISO Pyrethrins results in increased activity of CASP3 protein CTD PMID:27939866 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases activity ISO Pyrethrins results in increased activity of CASP9 protein CTD PMID:27939866 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Pyrethrins results in increased expression of CYP2B1 mRNA CTD PMID:18022748 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Pyrethrins results in increased expression of CYP2B2 mRNA CTD PMID:18022748 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Pyrethrins results in increased expression of CYP2B6 mRNA CTD PMID:18022748 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Pyrethrins inhibits the reaction [Potassium results in increased expression of FOS mRNA] CTD PMID:15527870 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Pyrethrins binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Pyrethrins results in increased cleavage of PARP1 protein CTD PMID:27939866 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Pyrethrins binds to and results in increased activity of PPARA protein CTD PMID:17084873 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
ricinoleic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 affects binding ISO ricinoleic acid analog binds to CNR1 protein CTD PMID:16406364 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO ricinoleic acid analog binds to and affects the activity of CNR2 protein CTD PMID:16406364 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Il4 interleukin 4 multiple interactions ISO ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] CTD PMID:7544037 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO ricinoleic acid binds to PTGDS protein CTD PMID:26456343 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO ricinoleic acid analog binds to and affects the activity of TRPV1 protein CTD PMID:16406364 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] CTD PMID:7544037 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      atom 19784
        nonmetal atom 19659
          carbon atom 19563
            organic molecular entity 19563
              olefinic compound 14457
                homoallylic alcohol 31
                  (+)-(2S,3R,9R)-pristinol 0
                  (+)-albicanol 0
                  (3Z,6Z,9Z)-dodecatrienol 0
                  (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
                  (9Z)-12-hydroxyoctadec-9-enoic acid + 7
                  (E)-3-decen-1-ol 0
                  10-epi-juneol 0
                  10-epi-pyriculol 0
                  12-hydroxyjasmonic acid + 0
                  2-methylene-1,4-butanediol 0
                  20-HEPE 0
                  2beta-hydroxy-5-epi-aristolochene 0
                  4-methylpent-3-en-1-ol + 0
                  5,20-diHEPE 0
                  5-(2-hydroxyethyl)isolongifol-4-ene 0
                  5-(2-hydroxyethyl)isolongifol-5-ene 0
                  6-hydroxyhex-3-enoic acid + 0
                  6-hydroxyhex-3-enoyl-CoA + 0
                  6-tuliposide A 0
                  Delta(12)-prostaglandin J3 0
                  N(5)-anhydromevalonyl-N(5)-hydroxy-L-ornithine 0
                  N-[(+)-12-hydroxy-7-isojasmonyl]isoleucine 0
                  N-[(3R)-12-hydroxyjasmonyl]-L-isoleucine 0
                  N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[5-hydroxy-3-(2-oxolanylmethyldisulfanyl)pent-2-en-2-yl]formamide 0
                  Thiamine disulfide 0
                  Tuliposide A 0
                  anhydromevalonyl-CoA 0
                  asperaculane G 0
                  chrysanthemol + 24
                  coprogen 0
                  coprogen B 0
                  desferricoprogen 0
                  desferricoprogen B 0
                  dihydropyriculariol 0
                  dihydropyriculol 0
                  drimendiol 0
                  drimenol + 4
                  eupatolide 0
                  ferrirubin 0
                  hex-3-en-1-ol + 1
                  isogeraniol + 0
                  isopentenyl alcohol + 0
                  marinolic acid C 0
                  methyl tuberonate 0
                  pyriculariol 0
                  pyriculol + 0
                  taxine B 0
                  triricinolein + 1
                  tuberonic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              organic hydroxy compound 18634
                                alcohol 14987
                                  aliphatic alcohol 11105
                                    homoallylic alcohol 31
                                      (+)-(2S,3R,9R)-pristinol 0
                                      (+)-albicanol 0
                                      (3Z,6Z,9Z)-dodecatrienol 0
                                      (4Z,7Z,10Z,13Z,16Z,19Z)-22-hydroxydocosahexaenoic acid 0
                                      (9Z)-12-hydroxyoctadec-9-enoic acid + 7
                                      (E)-3-decen-1-ol 0
                                      10-epi-juneol 0
                                      10-epi-pyriculol 0
                                      12-hydroxyjasmonic acid + 0
                                      2-methylene-1,4-butanediol 0
                                      20-HEPE 0
                                      2beta-hydroxy-5-epi-aristolochene 0
                                      4-methylpent-3-en-1-ol + 0
                                      5,20-diHEPE 0
                                      5-(2-hydroxyethyl)isolongifol-4-ene 0
                                      5-(2-hydroxyethyl)isolongifol-5-ene 0
                                      6-hydroxyhex-3-enoic acid + 0
                                      6-hydroxyhex-3-enoyl-CoA + 0
                                      6-tuliposide A 0
                                      Delta(12)-prostaglandin J3 0
                                      N(5)-anhydromevalonyl-N(5)-hydroxy-L-ornithine 0
                                      N-[(+)-12-hydroxy-7-isojasmonyl]isoleucine 0
                                      N-[(3R)-12-hydroxyjasmonyl]-L-isoleucine 0
                                      N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[5-hydroxy-3-(2-oxolanylmethyldisulfanyl)pent-2-en-2-yl]formamide 0
                                      Thiamine disulfide 0
                                      Tuliposide A 0
                                      anhydromevalonyl-CoA 0
                                      asperaculane G 0
                                      chrysanthemol + 24
                                      coprogen 0
                                      coprogen B 0
                                      desferricoprogen 0
                                      desferricoprogen B 0
                                      dihydropyriculariol 0
                                      dihydropyriculol 0
                                      drimendiol 0
                                      drimenol + 4
                                      eupatolide 0
                                      ferrirubin 0
                                      hex-3-en-1-ol + 1
                                      isogeraniol + 0
                                      isopentenyl alcohol + 0
                                      marinolic acid C 0
                                      methyl tuberonate 0
                                      pyriculariol 0
                                      pyriculol + 0
                                      taxine B 0
                                      triricinolein + 1
                                      tuberonic acid + 0
paths to the root

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