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Accession:CHEBI:134355 term browser browse the term
Definition:A member of the class of coumarins that is umbelliferone in which the phenolic hydrogen has been replaced by a geranyl group. Ii is isolated from several edible fruits and vegetables and exhibits a variety of therapeutic properties.
Synonyms:exact_synonym: 7-{[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy}-2H-1-benzopyran-2-one
 related_synonym: (E)-7-((3,7-Dimethylocta-2,6-dien-1-yl)oxy)-2H-chromen-2-one;   7-O-geranylumbelliferone;   7-geranyloxycoumarin;   Formula=C19H22O3;   InChI=1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+;   InChIKey=RSDDHGSKLOSQFK-RVDMUPIBSA-N;   SMILES=C12=CC(=CC=C1C=CC(O2)=O)OC/C=C(/CCC=C(C)C)\\C
 xref: CAS:495-02-3 "ChemIDplus";   CAS:495-02-3 "NIST Chemistry WebBook";   Chemspider:1267148;   HMDB:HMDB0034054;   KNApSAcK:C00029763
 xref_mesh: MESH:C105832
 xref: PMID:10426794 "Europe PMC";   PMID:10820092 "Europe PMC";   PMID:10840935 "Europe PMC";   PMID:10890030 "Europe PMC";   PMID:10919638 "Europe PMC";   PMID:11023542 "Europe PMC";   PMID:13155117 "Europe PMC";   PMID:15218316 "Europe PMC";   PMID:16012713 "Europe PMC";   PMID:16317159 "Europe PMC";   PMID:16395701 "Europe PMC";   PMID:16979634 "Europe PMC";   PMID:17151446 "Europe PMC";   PMID:17284254 "Europe PMC";   PMID:17301064 "Europe PMC";   PMID:17571970 "Europe PMC";   PMID:17898489 "Europe PMC";   PMID:18060855 "Europe PMC";   PMID:18444171 "Europe PMC";   PMID:19276534 "Europe PMC";   PMID:19444820 "Europe PMC";   PMID:19640308 "Europe PMC";   PMID:19688830 "Europe PMC";   PMID:20460732 "Europe PMC";   PMID:20681532 "Europe PMC";   PMID:20702762 "Europe PMC";   PMID:20863601 "Europe PMC";   PMID:20955144 "Europe PMC";   PMID:21705169 "Europe PMC";   PMID:21911903 "Europe PMC";   PMID:22038981 "Europe PMC";   PMID:22283649 "Europe PMC";   PMID:22471969 "Europe PMC";   PMID:22742512 "Europe PMC";   PMID:22754300 "Europe PMC";   PMID:22761031 "Europe PMC";   PMID:23083450 "Europe PMC";   PMID:23219792 "Europe PMC";   PMID:23320178 "Europe PMC";   PMID:23368941 "Europe PMC";   PMID:23495198 "Europe PMC";   PMID:23872723 "Europe PMC";   PMID:24070132 "Europe PMC";   PMID:24955102 "Europe PMC";   PMID:25147119 "Europe PMC";   PMID:25522543 "Europe PMC";   PMID:25620131 "Europe PMC";   PMID:25810889 "Europe PMC";   PMID:26351512 "Europe PMC";   PMID:26474388 "Europe PMC";   PMID:26730337 "Europe PMC";   PMID:26944297 "Europe PMC";   PMID:27130820 "Europe PMC";   PMID:27207438 "Europe PMC";   PMID:27420975 "Europe PMC";   PMID:27763495 "Europe PMC";   PMID:27771936 "SUBMITTER";   PMID:28383142 "Europe PMC";   PMID:9247600 "Europe PMC";   PMID:9395216 "Europe PMC";   PMID:9525276 "Europe PMC";   PMID:9635577 "Europe PMC";   Reaxys:1291239 "Reaxys";   Wikipedia:Auraptene

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auraptene term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,575 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 3 36,564,865 36,573,038 RGD:6480464
G Ccnb2 cyclin B2 JBrowse link 9 70,407,689 70,421,554 RGD:6480464
G Cdc45 cell division cycle 45 JBrowse link 16 18,780,447 18,811,972 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 10 69,335,146 69,352,912 RGD:6480464
G Cdkn2b cyclin dependent kinase inhibitor 2B JBrowse link 4 89,306,289 89,311,032 RGD:6480464
G Cdkn2c cyclin dependent kinase inhibitor 2C JBrowse link 4 109,660,876 109,666,756 RGD:6480464
G Chek1 checkpoint kinase 1 JBrowse link 9 36,708,482 36,726,658 RGD:6480464
G Chek2 checkpoint kinase 2 JBrowse link 5 110,839,800 110,874,140 RGD:6480464
G Ctnnb1 catenin (cadherin associated protein), beta 1 JBrowse link 9 120,933,400 120,960,507 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:6480464
G Dusp1 dual specificity phosphatase 1 JBrowse link 17 26,505,591 26,508,472 RGD:6480464
G E2f1 E2F transcription factor 1 JBrowse link 2 154,559,400 154,569,892 RGD:6480464
G E2f2 E2F transcription factor 2 JBrowse link 4 136,172,274 136,196,057 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha JBrowse link 6 67,035,096 67,037,407 RGD:6480464
G Jun jun proto-oncogene JBrowse link 4 95,049,036 95,052,222 RGD:6480464
G Kif20b kinesin family member 20B JBrowse link 19 34,922,335 34,975,750 RGD:6480464
G Mcm3 minichromosome maintenance complex component 3 JBrowse link 1 20,802,966 20,820,312 RGD:6480464
G Mcm6 minichromosome maintenance complex component 6 JBrowse link 1 128,331,575 128,359,705 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 JBrowse link 17 56,303,337 56,323,486 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20971
    role 20952
      chemical role 20281
        antioxidant 14255
          auraptene 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 20971
    subatomic particle 20965
      composite particle 20965
        hadron 20965
          baryon 20965
            nucleon 20965
              atomic nucleus 20965
                atom 20965
                  main group element atom 20803
                    p-block element atom 20803
                      carbon group element atom 20543
                        carbon atom 20519
                          organic molecular entity 20519
                            organic molecule 20371
                              organic cyclic compound 20047
                                organic heterocyclic compound 18970
                                  oxacycle 17202
                                    benzopyran 9583
                                      1-benzopyran 9288
                                        chromenes 909
                                          chromenone 832
                                            coumarins 542
                                              hydroxycoumarin 299
                                                umbelliferone 78
                                                  auraptene 24
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.