Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:aporphine alkaloid
go back to main search page
Accession:CHEBI:134209 term browser browse the term
Definition:Any benzylisoquinoline alkaloid that has a structure based on 4H-dibenzo[de,g]quinoline or its 3-methyl derivative.
Synonyms:related_synonym: aporphine alkaloids


show annotations for term's descendants           Sort by:
 
(S)-glaucine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases activity ISO glaucine results in increased activity of ABCB1 protein CTD PMID:23273999 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
(S)-magnoflorine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Citric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of phenylacetylglycine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uridine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein] CTD PMID:24709313 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein] CTD PMID:24709313 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
apomorphine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amy1a amylase, alpha 1A multiple interactions EXP Apomorphine results in increased secretion of and results in increased activity of AMY1A protein; Atenolol inhibits the reaction [Apomorphine results in increased secretion of and results in increased activity of AMY1A protein]; Metoclopramide inhibits the reaction [Apomorphine results in increased secretion of and results in increased activity of AMY1A protein] CTD PMID:21173550 NCBI chr 2:216,428,709...216,443,518
Ensembl chr 2:216,428,709...216,443,518
JBrowse link
G Avp arginine vasopressin increases expression
multiple interactions
ISO Apomorphine results in increased expression of AVP protein
Metoclopramide inhibits the reaction [Apomorphine results in increased expression of AVP protein]
CTD PMID:16575035 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form] CTD PMID:25633564 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A decreases expression ISO Apomorphine results in decreased expression of BMPR1A mRNA CTD PMID:25633564 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Cck cholecystokinin multiple interactions
decreases activity
EXP Naloxone inhibits the reaction [CCK protein results in decreased activity of Apomorphine] CTD PMID:3561887 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Cckbr cholecystokinin B receptor affects response to substance ISO CCKBR protein affects the susceptibility to Apomorphine CTD PMID:11702094 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions ISO Apomorphine binds to and results in increased activity of DRD1 protein; SCH 23390 inhibits the reaction [Apomorphine results in increased activity of DRD1 protein]
[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]
CTD PMID:8103921 PMID:15985612 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects response to substance
increases response to substance
ISO
EXP
[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole; Raclopride inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]
Risperidone inhibits the reaction [Apomorphine binds to and results in increased activity of DRD2 protein]
DRD2 protein affects the susceptibility to Apomorphine
DRD2 protein results in increased susceptibility to Apomorphine
CTD PMID:2571179 PMID:7520908 PMID:8103596 PMID:8103921 PMID:14639100 PMID:19497322 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 increases response to substance ISO DRD3 protein results in increased susceptibility to Apomorphine CTD PMID:19497322 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Apomorphine results in increased expression of FOS protein CTD PMID:10904129 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) decreases expression ISO Apomorphine results in decreased expression of FURIN mRNA CTD PMID:25633564 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions EXP GDNF protein affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gh1 growth hormone 1 increases secretion
increases expression
ISO Apomorphine results in increased secretion of GH1 protein
Apomorphine results in increased expression of GH1 protein
CTD PMID:993808 PMID:8889285 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions
decreases secretion
decreases expression
ISO Apomorphine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; Apomorphine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form]; Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA]
Apomorphine results in decreased secretion of HAMP protein modified form
Apomorphine results in decreased expression of HAMP mRNA
CTD PMID:25633564 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP [1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; [8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine; tertatolol inhibits the reaction [[1-((4-fluorobenzoylamino)ethyl)-4-(7-methoxy-1-naphthyl)piperazine hydrochloride binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine]; tertatolol inhibits the reaction [[8-Hydroxy-2-(di-n-propylamino)tetralin binds to and results in increased activity of HTR1A protein] which results in decreased susceptibility to Apomorphine] CTD PMID:8539317 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 increases response to substance
multiple interactions
EXP HTR6 protein results in increased susceptibility to Apomorphine
Ro4368554 inhibits the reaction [HTR6 protein results in increased susceptibility to Apomorphine]
CTD PMID:17920665 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Apomorphine inhibits the reaction [IL6 protein results in increased expression of HAMP mRNA] CTD PMID:25633564 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO Apomorphine inhibits the reaction [Oxidopamine results in increased phosphorylation of JUN protein] CTD PMID:14599342 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity ISO Apomorphine results in increased activity of ODC1 protein CTD PMID:10354516 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Penk proenkephalin multiple interactions EXP Apomorphine inhibits the reaction [Reserpine results in increased expression of PENK mRNA] CTD PMID:17719177 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Prl prolactin decreases expression ISO Apomorphine results in decreased expression of PRL protein CTD PMID:8889285 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Pvalb parvalbumin affects expression EXP Apomorphine affects the expression of PVALB protein CTD PMID:15238432 NCBI chr 7:119,428,657...119,443,674
Ensembl chr 7:119,429,019...119,441,487
JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance ISO RGS9 affects the susceptibility to Apomorphine CTD PMID:15728856 NCBI chr10:97,509,971...97,582,188
Ensembl chr10:97,509,971...97,582,188
JBrowse link
G Shh sonic hedgehog signaling molecule multiple interactions EXP SHH protein modified form affects the susceptibility to [Apomorphine co-treated with Oxidopamine] CTD PMID:11771942 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Apomorphine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Syt7 synaptotagmin 7 multiple interactions EXP [Reserpine co-treated with Apomorphine] results in increased expression of SYT7 mRNA CTD PMID:17719177 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Apomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA] CTD PMID:17719177 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
Boldine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 increases expression EXP boldine results in increased expression of ABCB11 mRNA; boldine results in increased expression of ABCB11 protein CTD PMID:25771127 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP boldine results in increased expression of ABCC2 mRNA CTD PMID:25771127 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Aqp8 aquaporin 8 increases expression EXP boldine results in increased expression of AQP8 mRNA CTD PMID:25771127 NCBI chr 1:193,424,818...193,430,665
Ensembl chr 1:193,424,812...193,430,676
JBrowse link
G Cat catalase multiple interactions ISO boldine inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of CAT protein] CTD PMID:32531310 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Drd1 dopamine receptor D1 affects binding
multiple interactions
EXP boldine analog binds to DRD1 protein
boldine analog inhibits the reaction [SCH 23390 binds to DRD1 protein]
CTD PMID:10785418 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO boldine inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein] CTD PMID:32531310 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression EXP boldine results in increased expression of NR0B2 mRNA CTD PMID:25771127 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases expression EXP boldine results in increased expression of NR1H4 mRNA CTD PMID:25771127 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Slc4a2 solute carrier family 4 member 2 increases expression EXP boldine results in increased expression of SLC4A2 mRNA CTD PMID:25771127 NCBI chr 4:7,264,677...7,282,355
Ensembl chr 4:7,264,683...7,281,223
JBrowse link
G Tert telomerase reverse transcriptase affects splicing
decreases activity
ISO boldine affects the splicing of TERT mRNA
boldine results in decreased activity of TERT protein
CTD PMID:25746354 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO boldine inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of TNF protein] CTD PMID:32531310 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP boldine results in increased expression of UGT1A1 mRNA CTD PMID:25771127 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        biochemical role 19304
          metabolite 19285
            alkaloid 5354
              isoquinoline alkaloid 1130
                benzylisoquinoline alkaloid 212
                  aporphine alkaloid 41
                    (+)-Cassythicine 0
                    (+)-Mecambroline 0
                    (+)-N-(methoxycarbonyl)-N-norboldine 0
                    (-)-Apoglaziovine 0
                    (-)-Caaverine 0
                    (-)-annonaine + 0
                    (6aS)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol 0
                    (8R)-13-methoxy-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,14-diol 0
                    (8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol 0
                    (8R)-7-prop-2-enyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-13,14-diol 0
                    (8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-13,14-diol 0
                    (8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol 0
                    (S)-1,2,9,10-tetramethoxy-6-methylaporphine(1+) 0
                    (S)-corytuberine + 2
                    (S)-glaucine + 1
                    (S)-magnoflorine 2
                    1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol 0
                    6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol 0
                    Adiantifoline 0
                    Annolobine 0
                    Boldine 12
                    Bracteoline 0
                    Cassyfiline 0
                    Dicentrine 0
                    Isoboldine 0
                    Isocorydine 0
                    Michelalbine 0
                    N-methylbulbocapnine(1+) 0
                    Pukateine 0
                    R-(-)-3-hydroxynornuciferine 0
                    R-(-)-actinodaphnine 0
                    R-(-)-asimilobine 0
                    R-(-)-norushinsunine 0
                    S-(+)-3-hydroxynornantenine 0
                    S-(+)-N-methylcorydine 0
                    Saxicolaline A 0
                    Tuduranine 0
                    Xylopine 0
                    actinodaphnine 0
                    apomorphine + 27
                    aporphine + 27
                    bulbocapnine + 0
                    isothebaine 0
                    laurolistine + 0
                    oxoaporphine alkaloid + 0
                    sinomendine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    main group molecular entity 19696
                      p-block molecular entity 19696
                        carbon group molecular entity 19599
                          organic molecular entity 19588
                            heteroorganic entity 19175
                              organonitrogen compound 18335
                                alkaloid 5354
                                  isoquinoline alkaloid 1130
                                    benzylisoquinoline alkaloid 212
                                      aporphine alkaloid 41
                                        (+)-Cassythicine 0
                                        (+)-Mecambroline 0
                                        (+)-N-(methoxycarbonyl)-N-norboldine 0
                                        (-)-Apoglaziovine 0
                                        (-)-Caaverine 0
                                        (-)-annonaine + 0
                                        (6aS)-6-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol 0
                                        (8R)-13-methoxy-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,14-diol 0
                                        (8R)-7-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol 0
                                        (8R)-7-prop-2-enyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-13,14-diol 0
                                        (8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-13,14-diol 0
                                        (8R)-7-propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,13,14-triol 0
                                        (S)-1,2,9,10-tetramethoxy-6-methylaporphine(1+) 0
                                        (S)-corytuberine + 2
                                        (S)-glaucine + 1
                                        (S)-magnoflorine 2
                                        1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-2,9-diol 0
                                        6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol 0
                                        Adiantifoline 0
                                        Annolobine 0
                                        Boldine 12
                                        Bracteoline 0
                                        Cassyfiline 0
                                        Dicentrine 0
                                        Isoboldine 0
                                        Isocorydine 0
                                        Michelalbine 0
                                        N-methylbulbocapnine(1+) 0
                                        Pukateine 0
                                        R-(-)-3-hydroxynornuciferine 0
                                        R-(-)-actinodaphnine 0
                                        R-(-)-asimilobine 0
                                        R-(-)-norushinsunine 0
                                        S-(+)-3-hydroxynornantenine 0
                                        S-(+)-N-methylcorydine 0
                                        Saxicolaline A 0
                                        Tuduranine 0
                                        Xylopine 0
                                        actinodaphnine 0
                                        apomorphine + 27
                                        aporphine + 27
                                        bulbocapnine + 0
                                        isothebaine 0
                                        laurolistine + 0
                                        oxoaporphine alkaloid + 0
                                        sinomendine 0
paths to the root