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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:picrotoxin
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Accession:CHEBI:134126 term browser browse the term
Definition:A mixture consisting of equimolar amounts of picrotoxinin and picrotin found in the climbing plant Anamirta cocculus.
Synonyms:exact_synonym: (1R,3R,5S,8S,9R,12S,13R,14R)-1-hydroxy-13-methyl-14-(prop-1-en-2-yl)-4,7,10-trioxapentacyclo[6.4.1.1(9,12).0(3,5).0(5,13)]tetradecane-6,11-dione -- (1R,3R,5S,8S,9R,12S,13R,14S)-1-hydroxy-14-(2-hydroxypropan-2-yl)-13-methyl-4,7,10-trioxapentacyclo[6.4.1.1(9,12).0(3,5).0(5,13)]tetradecane-6,11-dione (1:1)
 related_synonym: Cocculin;   Cocculus;   Coques du levant;   picrotoxine;   picrotoxinin - picrotin (1:1)
 xref: CAS:124-87-8;   HMDB:HMDB0014609
 xref_mesh: MESH:D010852
 xref: Reaxys:21526388;   Wikipedia:Picrotoxin


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picrotoxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 increases expression
decreases expression
EXP Picrotoxin results in increased expression of ABCC8 mRNA; Picrotoxin results in increased expression of ABCC8 protein
Picrotoxin results in decreased expression of ABCC8 mRNA
CTD PMID:18021373 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 decreases expression EXP Picrotoxin results in decreased expression of ACSL5 mRNA CTD PMID:15170462 NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 decreases expression EXP Picrotoxin results in decreased expression of ACSL6 mRNA CTD PMID:15170462 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
G Adcy4 adenylate cyclase 4 increases expression EXP Picrotoxin results in increased expression of ADCY4 mRNA CTD PMID:15170462 NCBI chr15:29,266,280...29,282,153
Ensembl chr15:29,266,287...29,282,108
JBrowse link
G Adra1b adrenoceptor alpha 1B increases expression EXP Picrotoxin results in increased expression of ADRA1B mRNA CTD PMID:15170462 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression EXP Picrotoxin results in increased expression of ADRA2A mRNA CTD PMID:15170462 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression EXP Picrotoxin results in increased expression of ADRB2 mRNA CTD PMID:15170462 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression EXP Picrotoxin results in increased expression of AGTR1A mRNA CTD PMID:15170462 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Agtr2 angiotensin II receptor, type 2 decreases expression EXP Picrotoxin results in decreased expression of AGTR2 mRNA CTD PMID:15170462 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057
JBrowse link
G Alad aminolevulinate dehydratase decreases activity
multiple interactions
ISO Picrotoxin results in decreased activity of ALAD protein
carvacryl acetate inhibits the reaction [Picrotoxin results in decreased activity of ALAD protein]
CTD PMID:25490531 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression EXP Picrotoxin results in increased expression of ALDOB mRNA CTD PMID:15170462 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type increases expression EXP Picrotoxin results in increased expression of ALOX12 mRNA CTD PMID:15170462 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression EXP Picrotoxin results in increased expression of ALOX5AP mRNA CTD PMID:15170462 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta decreases expression EXP Picrotoxin results in decreased expression of ATP5F1D mRNA CTD PMID:15170462 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression EXP Picrotoxin results in decreased expression of ATP5PO mRNA CTD PMID:15170462 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP Picrotoxin results in decreased expression of BCL2L1 mRNA CTD PMID:15170462 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression
decreases methylation
ISO
EXP
Picrotoxin results in increased expression of BDNF mRNA
Picrotoxin results in increased expression of BDNF protein
Picrotoxin results in decreased methylation of BDNF promoter
CTD PMID:11279263 PMID:18184782 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Calb1 calbindin 1 decreases expression EXP Picrotoxin results in decreased expression of CALB1 protein CTD PMID:15382257 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Calb2 calbindin 2 decreases expression EXP Picrotoxin results in decreased expression of CALB2 protein CTD PMID:15382257 NCBI chr19:38,114,435...38,141,438
Ensembl chr19:38,114,424...38,141,438
JBrowse link
G Casp2 caspase 2 increases expression EXP Picrotoxin results in increased expression of CASP2 mRNA CTD PMID:15170462 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Cckar cholecystokinin A receptor increases expression EXP Picrotoxin results in increased expression of CCKAR mRNA CTD PMID:15170462 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
JBrowse link
G Cckbr cholecystokinin B receptor increases expression EXP Picrotoxin results in increased expression of CCKBR mRNA CTD PMID:15170462 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Ccnd2 cyclin D2 decreases expression EXP Picrotoxin results in decreased expression of CCND2 mRNA CTD PMID:15170462 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnd3 cyclin D3 increases expression EXP Picrotoxin results in increased expression of CCND3 mRNA CTD PMID:15170462 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression EXP Picrotoxin results in increased expression of CCR2 mRNA CTD PMID:15170462 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 increases expression EXP Picrotoxin results in increased expression of CHRM1 mRNA CTD PMID:15170462 NCBI chr 1:205,567,046...205,583,001
Ensembl chr 1:205,567,220...205,582,356
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 increases expression EXP Picrotoxin results in increased expression of CHRM2 mRNA CTD PMID:15170462 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 increases expression EXP Picrotoxin results in increased expression of CHRM3 mRNA CTD PMID:15170462 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Picrotoxin results in increased expression of CPT1A mRNA CTD PMID:15170462 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B increases expression EXP Picrotoxin results in increased expression of CPT1B mRNA CTD PMID:15170462 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP Picrotoxin results in increased expression of CXCR4 mRNA CTD PMID:15170462 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 decreases expression EXP Picrotoxin results in decreased expression of DECR1 mRNA CTD PMID:15170462 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression EXP Picrotoxin results in decreased expression of DHCR7 mRNA CTD PMID:15170462 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Drd4 dopamine receptor D4 increases expression EXP Picrotoxin results in increased expression of DRD4 mRNA CTD PMID:15170462 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP Picrotoxin inhibits the reaction [EDN1 protein results in decreased secretion of Norepinephrine] CTD PMID:12184995 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Edn3 endothelin 3 multiple interactions EXP Picrotoxin inhibits the reaction [EDN3 protein results in decreased secretion of Norepinephrine] CTD PMID:12184995 NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093
JBrowse link
G Ednrb endothelin receptor type B decreases expression EXP Picrotoxin results in decreased expression of EDNRB mRNA CTD PMID:15170462 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Picrotoxin results in increased expression of FOS; Picrotoxin results in increased expression of FOS mRNA CTD PMID:1380685 PMID:9500968 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression EXP Picrotoxin results in increased expression of FOSL1 mRNA CTD PMID:15170462 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Fshr follicle stimulating hormone receptor increases expression EXP Picrotoxin results in increased expression of FSHR mRNA CTD PMID:15170462 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Fzd2 frizzled class receptor 2 increases expression EXP Picrotoxin results in increased expression of FZD2 mRNA CTD PMID:15170462 NCBI chr10:87,561,866...87,563,776
Ensembl chr10:87,561,326...87,565,334
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions EXP 1-(4-chlorophenyl)-3-(3-(4-chlorophenyl)-5,5-dimethyl-1-(3-(5-nitrofuran-2-yl)allyldienehydrazinocarbonylmethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea inhibits the reaction [Picrotoxin affects the localization of GABBR2 protein]; Picrotoxin results in decreased expression of and affects the localization of GABBR2 protein CTD PMID:24482233 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO
EXP
delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD PMID:9316872 PMID:14637376 PMID:17054655 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 multiple interactions ISO Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [Chloralose results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 PMID:14637376 NCBI chr14:37,096,995...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions ISO Picrotoxin inhibits the reaction [Chloralose results in increased activity of [GABRA2 protein binds to GABRB1 protein]] CTD PMID:10683198 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO
EXP
Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD PMID:14637376 PMID:17054655 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 multiple interactions ISO delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]] CTD PMID:9316872 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO
EXP
delta-hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Hexachlorocyclohexane inhibits the reaction [Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]]; Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]]; Picrotoxin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]
Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Picrotoxin results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD PMID:9316872 PMID:14637376 PMID:17054655 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression EXP Picrotoxin results in increased expression of GAD1 mRNA CTD PMID:15170462 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gad2 glutamate decarboxylase 2 increases response to substance
increases expression
ISO
EXP
GAD2 gene mutant form results in increased susceptibility to Picrotoxin
Picrotoxin results in increased expression of GAD2 mRNA; Picrotoxin results in increased expression of GAD2 protein
CTD PMID:8954991 PMID:15170462 PMID:15382257 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions ISO Picrotoxin binds to and results in decreased activity of GLRA1 protein CTD PMID:15081878 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162
JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression EXP Picrotoxin results in decreased expression of GNAI1 mRNA CTD PMID:15170462 NCBI chr 4:16,813,941...16,898,111
Ensembl chr 4:16,814,001...16,896,417
JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression EXP Picrotoxin results in decreased expression of GNAI2 mRNA CTD PMID:15170462 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
JBrowse link
G Gng8 G protein subunit gamma 8 increases expression EXP Picrotoxin results in increased expression of GNG8 mRNA CTD PMID:15170462 NCBI chr 1:77,564,512...77,568,371
Ensembl chr 1:77,564,515...77,568,371
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression EXP Picrotoxin results in increased expression of GNRHR mRNA CTD PMID:15170462 NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 decreases expression EXP Picrotoxin results in decreased expression of GPD1 mRNA CTD PMID:15170462 NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta decreases expression EXP Picrotoxin results in decreased expression of HADHB mRNA CTD PMID:15170462 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 increases expression EXP Picrotoxin results in increased expression of HTR6 mRNA CTD PMID:15170462 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP Picrotoxin results in decreased expression of IDI1 mRNA CTD PMID:15170462 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 decreases expression
increases expression
EXP Picrotoxin results in decreased expression of KCNJ11 mRNA; Picrotoxin results in decreased expression of KCNJ11 protein
Picrotoxin results in increased expression of KCNJ11 mRNA; Picrotoxin results in increased expression of KCNJ11 protein
CTD PMID:18021373 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases expression EXP Picrotoxin results in decreased expression of KRAS mRNA CTD PMID:15170462 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Ldhb lactate dehydrogenase B decreases expression EXP Picrotoxin results in decreased expression of LDHB mRNA CTD PMID:15170462 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
JBrowse link
G Ldhc lactate dehydrogenase C increases expression EXP Picrotoxin results in increased expression of LDHC mRNA CTD PMID:15170462 NCBI chr 1:97,385,984...97,403,382
Ensembl chr 1:97,382,379...97,403,378
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor increases expression EXP Picrotoxin results in increased expression of LHCGR mRNA CTD PMID:15170462 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Lpl lipoprotein lipase decreases expression EXP Picrotoxin results in decreased expression of LPL mRNA CTD PMID:15170462 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lta4h leukotriene A4 hydrolase increases expression EXP Picrotoxin results in increased expression of LTA4H mRNA CTD PMID:15170462 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600
JBrowse link
G Mc4r melanocortin 4 receptor increases expression EXP Picrotoxin results in increased expression of MC4R mRNA CTD PMID:15170462 NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
JBrowse link
G Mvk mevalonate kinase increases expression EXP Picrotoxin results in increased expression of MVK mRNA CTD PMID:15170462 NCBI chr12:42,141,391...42,158,858
Ensembl chr12:42,141,384...42,158,882
JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 decreases expression EXP Picrotoxin results in decreased expression of NDUFS6 mRNA CTD PMID:15170462 NCBI chr 2:27,201,713...27,202,126
Ensembl chr 2:27,201,713...27,202,258
JBrowse link
G Npy1r neuropeptide Y receptor Y1 increases expression EXP Picrotoxin results in increased expression of NPY1R mRNA CTD PMID:15170462 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Oprk1 opioid receptor, kappa 1 increases expression EXP Picrotoxin results in increased expression of OPRK1 mRNA CTD PMID:15170462 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprm1 opioid receptor, mu 1 increases expression EXP Picrotoxin results in increased expression of OPRM1 mRNA CTD PMID:15170462 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Pde4d phosphodiesterase 4D increases expression EXP Picrotoxin results in increased expression of PDE4D mRNA CTD PMID:15170462 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pfkp phosphofructokinase, platelet decreases expression EXP Picrotoxin results in decreased expression of PFKP mRNA CTD PMID:15170462 NCBI chr17:63,729,743...63,794,021
Ensembl chr17:63,729,780...63,794,018
JBrowse link
G Pgam1 phosphoglycerate mutase 1 decreases expression EXP Picrotoxin results in decreased expression of PGAM1 mRNA CTD PMID:15170462 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgam2 phosphoglycerate mutase 2 increases expression EXP Picrotoxin results in increased expression of PGAM2 mRNA CTD PMID:15170462 NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940
JBrowse link
G Prkcd protein kinase C, delta decreases expression EXP Picrotoxin results in decreased expression of PRKCD mRNA CTD PMID:15170462 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkce protein kinase C, epsilon decreases expression EXP Picrotoxin results in decreased expression of PRKCE mRNA CTD PMID:15170462 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Psma3 proteasome 20S subunit alpha 3 decreases expression EXP Picrotoxin results in decreased expression of PSMA3 mRNA CTD PMID:15170462 NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965
JBrowse link
G Psma4 proteasome 20S subunit alpha 4 decreases expression EXP Picrotoxin results in decreased expression of PSMA4 mRNA CTD PMID:15170462 NCBI chr 8:55,340,431...55,347,893
Ensembl chr 8:55,340,386...55,347,890
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 increases expression EXP Picrotoxin results in increased expression of PSMB8 mRNA CTD PMID:15170462 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 decreases expression EXP Picrotoxin results in decreased expression of PSMC3 mRNA CTD PMID:15170462 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
JBrowse link
G Pvalb parvalbumin decreases expression EXP Picrotoxin results in decreased expression of PVALB protein CTD PMID:15382257 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
JBrowse link
G Ryr2 ryanodine receptor 2 increases expression EXP Picrotoxin results in increased expression of RYR2 mRNA CTD PMID:21113126 NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G Smad1 SMAD family member 1 decreases expression EXP Picrotoxin results in decreased expression of SMAD1 mRNA CTD PMID:15170462 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
G Smad3 SMAD family member 3 increases expression EXP Picrotoxin results in increased expression of SMAD3 mRNA CTD PMID:15170462 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad7 SMAD family member 7 decreases expression EXP Picrotoxin results in decreased expression of SMAD7 mRNA CTD PMID:15170462 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Sqle squalene epoxidase decreases expression EXP Picrotoxin results in decreased expression of SQLE mRNA CTD PMID:15170462 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Sstr2 somatostatin receptor 2 increases expression EXP Picrotoxin results in increased expression of SSTR2 mRNA CTD PMID:15170462 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 increases expression EXP Picrotoxin results in increased expression of TGFBR3 mRNA CTD PMID:15170462 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
JBrowse link
G Trhr thyrotropin releasing hormone receptor decreases expression EXP Picrotoxin results in decreased expression of TRHR mRNA CTD PMID:15170462 NCBI chr 7:75,348,672...75,393,310
Ensembl chr 7:75,348,672...75,393,309
JBrowse link
G Tshr thyroid stimulating hormone receptor increases expression EXP Picrotoxin results in increased expression of TSHR mRNA CTD PMID:15170462 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP Picrotoxin results in increased expression of UCP2 mRNA CTD PMID:15170462 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP Picrotoxin results in increased expression of UCP3 mRNA CTD PMID:15170462 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    chemical entity 19812
      chemical substance 12981
        mixture 12153
          picrotoxin 94
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic ester 15889
                                        lactone 11245
                                          gamma-lactone 6749
                                            picrotoxinin 100
                                              picrotin 94
                                                picrotoxin 94
paths to the root