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ONTOLOGY REPORT - ANNOTATIONS


Term:N-hydroxy-PhIP
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Accession:CHEBI:133920 term browser browse the term
Definition:An imidazopyridine that is 1H--imidazo[4,5-b]pyridine which is substituted at positions 1, 2, and 6 by methyl, hydoxyamino, and phenyl groups, respectively. The active metabolite of the dietary carcinogen PhIP.
Synonyms:exact_synonym: N-(1-methyl-6-phenyl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ylidene)hydroxylamine
 related_synonym: 2-Hydroxyamino-PhIP;   2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine;   Formula=C13H12N4O;   InChI=1S/C13H12N4O/c1-17-11-7-10(9-5-3-2-4-6-9)8-14-12(11)15-13(17)16-18/h2-8,18H,1H3,(H,14,15,16);   InChIKey=DCVWQAGUQFBCTF-UHFFFAOYSA-N;   N-OH-PhIP;   SMILES=CN1C=2C=C(C=NC2N=C1NO)C3=CC=CC=C3
 xref: CAS:124489-20-9;   ChemIDplus:94711;   KEGG:C20286
 xref_mesh: MESH:C060533
 xref: PMID:10357796;   PMID:10837010;   PMID:11196146;   PMID:11408353;   PMID:11442279;   PMID:11700987;   PMID:11834212;   PMID:12175520;   PMID:12473729;   PMID:12773763;   PMID:15310245;   PMID:16137733;   PMID:17122891;   PMID:17638922;   PMID:20708442;   PMID:2233839;   PMID:24334255;   PMID:24718704;   PMID:25815793;   PMID:26270892;   PMID:27032077;   PMID:27984695;   PMID:7728954;   PMID:7852185;   PMID:8142010;   PMID:8199311;   PMID:8600367;   PMID:9760588;   Reaxys:8393164


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N-hydroxy-PhIP term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B JBrowse link 4 22,225,123 22,307,577 RGD:6480464
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Gsta1 glutathione S-transferase alpha 1 JBrowse link 9 27,366,404 27,381,004 RGD:6480464
G Gsta3 glutathione S-transferase alpha 3 JBrowse link 9 27,357,490 27,417,023 RGD:6480464
G Gsta4 glutathione S-transferase alpha 4 JBrowse link 8 85,497,557 85,514,732 RGD:6480464
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Nat1 N-acetyltransferase 1 JBrowse link 16 23,970,742 23,991,573 RGD:6480464
G Nat2 N-acetyltransferase 2 JBrowse link 16 23,960,709 23,991,570 RGD:6480464
G Pdia3 protein disulfide isomerase family A, member 3 JBrowse link 3 113,376,983 113,400,707 RGD:6480464
G Rab7a RAB7A, member RAS oncogene family JBrowse link 4 119,910,461 119,963,065 RGD:6480464
G Rps7 ribosomal protein S7 JBrowse link 6 47,899,525 47,904,389 RGD:6480464
G Sar1a secretion associated, Ras related GTPase 1A JBrowse link 20 31,298,269 31,310,676 RGD:6480464
G Sult1a1 sulfotransferase family 1A member 1 JBrowse link 1 198,100,586 198,104,106 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:6480464
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 JBrowse link 9 95,256,628 95,302,822 RGD:6480464
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464

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  CHEBI ontology 19790
    role 19738
      biological role 19737
        aetiopathogenetic role 18840
          genotoxin 16476
            N-hydroxy-PhIP 27
Path 2
Term Annotations click to browse term
  CHEBI ontology 19790
    subatomic particle 19788
      composite particle 19788
        hadron 19788
          baryon 19788
            nucleon 19788
              atomic nucleus 19788
                atom 19788
                  main group element atom 19674
                    main group molecular entity 19674
                      s-block molecular entity 19416
                        hydrogen molecular entity 19407
                          hydrides 18389
                            inorganic hydride 17221
                              pnictogen hydride 17184
                                nitrogen hydride 17018
                                  azane 16713
                                    ammonia 16712
                                      organic amino compound 16711
                                        primary amino compound 7858
                                          PhIP 578
                                            N-hydroxy-PhIP 27
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