CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: fatty acid oxidation inhibitor
Accession: CHEBI:133190
browse the term
Definition: A compound that inhibits the oxidation of any fatty acid.
Synonyms: related_synonym: fatty acid oxidation inhibitors
xref: Wikipedia:Fatty_acid_oxidation_inhibitors
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Apoa1
apolipoprotein A-I
decreases expression
ISO
2-bromopalmitate results in decreased expression of APOA1 mRNA
CTD
PMID:7556148
NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
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Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA]
CTD
PMID:30076181
NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
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Fas
Fas (TNF receptor superfamily member 6)
decreases expression
ISO
2-bromopalmitate results in decreased expression of FAS mRNA
CTD
PMID:16712844
NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
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Gapdh
glyceraldehyde-3-phosphate dehydrogenase
increases activity
ISO
2-bromopalmitate results in increased activity of GAPDH protein
CTD
PMID:10650946
NCBI chr 6:125,138,815...125,143,430
Ensembl chr 6:125,138,678...125,143,430
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Ifit3
interferon-induced protein with tetratricopeptide repeats 3
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA]
CTD
PMID:30076181
NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131
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Irf1
interferon regulatory factor 1
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IRF1 mRNA]
CTD
PMID:30076181
NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
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Lat2
linker for activation of T cells family, member 2
decreases expression
ISO
2-bromopalmitate results in decreased expression of LAT2 protein
CTD
PMID:23001822
NCBI chr 5:134,628,957...134,648,637
Ensembl chr 5:134,628,876...134,643,879
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Ldlr
low density lipoprotein receptor
increases expression
ISO
2-bromopalmitate results in increased expression of LDLR mRNA
CTD
PMID:23150725
NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
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Lrat
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)
increases expression
ISO
2-bromopalmitate results in increased expression of LRAT mRNA
CTD
PMID:12576510
NCBI chr 3:82,799,889...82,811,281
Ensembl chr 3:82,799,886...82,811,280
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Ly6e
lymphocyte antigen 6 complex, locus E
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of LY6E mRNA]
CTD
PMID:30076181
NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752
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Mpo
myeloperoxidase
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in decreased expression of MPO mRNA]
CTD
PMID:30076181
NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
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Ppard
peroxisome proliferator activator receptor delta
multiple interactions increases activity
EXP ISO
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein] 2-bromopalmitate results in increased activity of PPARD protein
CTD
PMID:15997096 PMID:21543282 PMID:23150725
NCBI chr17:28,451,657...28,520,446
Ensembl chr17:28,451,674...28,520,448
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Pparg
peroxisome proliferator activated receptor gamma
increases expression
ISO
2-bromopalmitate results in increased expression of PPARG protein
CTD
PMID:10650946
NCBI chr 6:115,337,840...115,467,365
Ensembl chr 6:115,337,912...115,467,360
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Rara
retinoic acid receptor, alpha
multiple interactions
ISO
2-bromopalmitate binds to and results in increased expression of RARA protein; 2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; 2-bromopalmitate inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; [2-bromopalmitate results in increased susceptibility to Tretinoin] which results in increased expression of RARA protein
CTD
PMID:30076181
NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768
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Rarb
retinoic acid receptor, beta
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of RARB mRNA]
CTD
PMID:30076181
NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924
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Rbp1
retinol binding protein 1, cellular
increases expression
ISO
2-bromopalmitate results in increased expression of RBP1 mRNA
CTD
PMID:12576510
NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628
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Rxra
retinoid X receptor alpha
multiple interactions
EXP
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]
CTD
PMID:15997096
NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
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Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of SPI1 mRNA]
CTD
PMID:30076181
NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101
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Tgm2
transglutaminase 2, C polypeptide
multiple interactions
ISO
2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA]
CTD
PMID:30076181
NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356
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Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
increases expression
ISO
2-bromopalmitate results in increased expression of UCP2 mRNA
CTD
PMID:11341955
NCBI chr 7:100,142,544...100,148,836
Ensembl chr 7:100,142,544...100,151,227
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