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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fatty acid oxidation inhibitor
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Accession:CHEBI:133190 term browser browse the term
Definition:A compound that inhibits the oxidation of any fatty acid.
Synonyms:related_synonym: fatty acid oxidation inhibitors
 xref: Wikipedia:Fatty_acid_oxidation_inhibitors



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2-bromohexadecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A-I decreases expression ISO 2-bromopalmitate results in decreased expression of APOA1 mRNA CTD PMID:7556148 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA] CTD PMID:30076181 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Fas Fas (TNF receptor superfamily member 6) decreases expression ISO 2-bromopalmitate results in decreased expression of FAS mRNA CTD PMID:16712844 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases activity ISO 2-bromopalmitate results in increased activity of GAPDH protein CTD PMID:10650946 NCBI chr 6:125,138,815...125,143,430
Ensembl chr 6:125,138,678...125,143,430
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA] CTD PMID:30076181 NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IRF1 mRNA] CTD PMID:30076181 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Lat2 linker for activation of T cells family, member 2 decreases expression ISO 2-bromopalmitate results in decreased expression of LAT2 protein CTD PMID:23001822 NCBI chr 5:134,628,957...134,648,637
Ensembl chr 5:134,628,876...134,643,879
JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO 2-bromopalmitate results in increased expression of LDLR mRNA CTD PMID:23150725 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) increases expression ISO 2-bromopalmitate results in increased expression of LRAT mRNA CTD PMID:12576510 NCBI chr 3:82,799,889...82,811,281
Ensembl chr 3:82,799,886...82,811,280
JBrowse link
G Ly6e lymphocyte antigen 6 complex, locus E multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of LY6E mRNA] CTD PMID:30076181 NCBI chr15:74,826,874...74,831,753
Ensembl chr15:74,826,900...74,831,752
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in decreased expression of MPO mRNA] CTD PMID:30076181 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Ppard peroxisome proliferator activator receptor delta multiple interactions
increases activity
EXP
ISO
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]
2-bromopalmitate results in increased activity of PPARD protein
CTD PMID:15997096 PMID:21543282 PMID:23150725 NCBI chr17:28,451,657...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma increases expression ISO 2-bromopalmitate results in increased expression of PPARG protein CTD PMID:10650946 NCBI chr 6:115,337,840...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO 2-bromopalmitate binds to and results in increased expression of RARA protein; 2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; 2-bromopalmitate inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; [2-bromopalmitate results in increased susceptibility to Tretinoin] which results in increased expression of RARA protein CTD PMID:30076181 NCBI chr11:98,818,626...98,865,768
Ensembl chr11:98,818,644...98,865,768
JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of RARB mRNA] CTD PMID:30076181 NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924
JBrowse link
G Rbp1 retinol binding protein 1, cellular increases expression ISO 2-bromopalmitate results in increased expression of RBP1 mRNA CTD PMID:12576510 NCBI chr 9:98,305,014...98,328,604
Ensembl chr 9:98,305,014...98,328,628
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions EXP 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein] CTD PMID:15997096 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Spi1 spleen focus forming virus (SFFV) proviral integration oncogene multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of SPI1 mRNA] CTD PMID:30076181 NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101
JBrowse link
G Tgm2 transglutaminase 2, C polypeptide multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA] CTD PMID:30076181 NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) increases expression ISO 2-bromopalmitate results in increased expression of UCP2 mRNA CTD PMID:11341955 NCBI chr 7:100,142,544...100,148,836
Ensembl chr 7:100,142,544...100,151,227
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 22001
    role 21987
      biological role 21984
        biochemical role 21280
          fatty acid oxidation inhibitor 20
            2-bromohexadecanoic acid 20
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