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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:quininib
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Accession:CHEBI:133170 term browser browse the term
Definition:A styrylquinoline that is trans-2-styrylquinoline in which the the phenyl group has been substituted at position 2 by a hydroxy group. It is an anti-angiogenic compound that exerts a dose-dependent antagonism of the cysteinyl leukotriene pathway, preferentially antagonising cysteinyl leukotriene receptor 1. The major species at pH 7.3
Synonyms:exact_synonym: 2-[(E)-2-(quinolin-2-yl)vinyl]phenol
 related_synonym: Formula=C17H13NO;   InChI=1S/C17H13NO/c19-17-8-4-2-6-14(17)10-12-15-11-9-13-5-1-3-7-16(13)18-15/h1-12,19H/b12-10+;   InChIKey=NXNDEWNGCMCWMA-ZRDIBKRKSA-N;   SMILES=C1=2C(C=CC=C1)=NC(=CC2)/C=C/C=3C(=CC=CC3)O
 xref: CAS:1379458-56-6;   PMID:26846851
 cyclic_relationship: is_conjugate_base_of CHEBI:133233


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Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      application 0
        pharmaceutical 0
          drug 0
            angiogenesis inhibitor 0
              quininib 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            organic molecule 0
                              organic cyclic compound 0
                                organic heterocyclic compound 0
                                  organonitrogen heterocyclic compound 0
                                    quinolines 0
                                      styrylquinoline 0
                                        2-styrylquinoline 0
                                          trans-2-styrylquinoline 0
                                            quininib 0
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