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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:graphene oxide
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Accession:CHEBI:132889 term browser browse the term
Definition:A single carbon layer of the graphite oxide structure.
Synonyms:xref_mesh: MESH:C000628730


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graphene oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO [[graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein] which results in increased expression of RAC1 protein; [graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein CTD PMID:31504961 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
affects expression
ISO graphene oxide results in increased expression of BAX protein
graphene oxide affects the expression of BAX mRNA
CTD PMID:30239936 PMID:32070776 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO graphene oxide results in decreased expression of BCL2 mRNA; graphene oxide results in decreased expression of BCL2 protein CTD PMID:30239936 PMID:32070776 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
ISO dorsomorphin inhibits the reaction [graphene oxide results in increased expression of BECN1 protein] CTD PMID:32430275 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex decreases expression ISO graphene oxide results in decreased expression of CHUK protein CTD PMID:30239936 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Efcab3 EF-hand calcium binding domain 3 increases expression ISO graphene oxide results in increased expression of EFCAB3 mRNA CTD PMID:29348435 NCBI chr10:93,304,559...93,332,849
Ensembl chr10:93,305,969...93,332,702
JBrowse link
G Hmgb1 high mobility group box 1 increases secretion
multiple interactions
ISO graphene oxide results in increased secretion of HMGB1 protein
2',3'-dialdehyde ATP inhibits the reaction [graphene oxide results in increased secretion of HMGB1 protein]; [[graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein] which results in increased expression of RAC1 protein; [graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein; Adenosine Triphosphate promotes the reaction [graphene oxide results in increased secretion of HMGB1 protein]; graphene oxide results in increased localization of and results in increased secretion of HMGB1 protein; P2RX7 protein affects the reaction [graphene oxide results in increased secretion of HMGB1 protein]
CTD PMID:31504961 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Mir21 microRNA 21 affects expression ISO graphene oxide affects the expression of MIR21 mRNA CTD PMID:32070776 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir29a microRNA 29a affects expression ISO graphene oxide affects the expression of MIR29A mRNA CTD PMID:32070776 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mmp2 matrix metallopeptidase 2 increases expression ISO graphene oxide results in increased expression of MMP2 mRNA CTD PMID:31504961 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation
multiple interactions
ISO graphene oxide results in decreased phosphorylation of MTOR protein
dorsomorphin inhibits the reaction [graphene oxide results in decreased phosphorylation of MTOR protein]
CTD PMID:32430275 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression ISO graphene oxide results in increased expression of NFKBIA protein CTD PMID:30239936 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO P2RX7 protein affects the reaction [graphene oxide results in increased secretion of HMGB1 protein] CTD PMID:31504961 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Pde6c phosphodiesterase 6C increases expression ISO graphene oxide results in increased expression of PDE6C mRNA CTD PMID:29348435 NCBI chr 1:256,822,099...256,885,879
Ensembl chr 1:256,822,334...256,877,810
JBrowse link
G Pten phosphatase and tensin homolog increases expression
decreases expression
ISO graphene oxide results in increased expression of PTEN protein
graphene oxide results in decreased expression of PTEN mRNA
CTD PMID:32070776 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO [[graphene oxide results in increased secretion of HMGB1 protein] which results in increased expression of and results in increased activity of AGER protein] which results in increased expression of RAC1 protein CTD PMID:31504961 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
decreases expression
ISO dorsomorphin inhibits the reaction [graphene oxide results in decreased expression of SQSTM1 protein] CTD PMID:32430275 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 decreases expression ISO graphene oxide results in decreased expression of TIMP2 mRNA CTD PMID:31504961 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tnf tumor necrosis factor increases expression ISO graphene oxide results in increased expression of TNF mRNA CTD PMID:30549182 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Wdr49 WD repeat domain 49 increases expression ISO graphene oxide results in increased expression of WDR49 mRNA CTD PMID:29348435 NCBI chr 2:173,675,780...173,800,840
Ensembl chr 2:173,676,089...173,836,854
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    chemical entity 19810
      molecular entity 19808
        elemental molecular entity 16251
          elemental carbon 8789
            graphene 399
              graphene oxide 20
                graphite oxide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon group molecular entity 19599
                          organic molecular entity 19588
                            elemental carbon 8789
                              graphene 399
                                graphene oxide 20
                                  graphite oxide 0
paths to the root