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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:132237 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-3,4-methylenedioxy-N-ethylamphetamine3,4-methylenedioxy-N-ethylamphetamine.
Synonyms:related_synonym: 3,4-methylenedioxy-N-ethylamphetamine;   Eve;   MDE;   MDEA;   N-ethyl MDA;   N-ethyl-alpha-methyl-3,4-(methylenedioxy)phenethylamine
 xref: CAS:82801-81-8;   DrugBank:DB01566
 xref_mesh: MESH:C051800
 xref: PMID:10533279;   PMID:10672974;   PMID:15179441;   PMID:19007498;   PMID:22564759;   PMID:24970379;   PMID:25029504;   PMID:25933611;   PMID:26538543;   PMID:26654084;   PMID:26829334;   PMID:26888521;   PMID:8563033;   PMID:8735473;   PMID:9549899;   Reaxys:4184143;   Wikipedia:Methylenedioxyethylamphetamine

show annotations for term's descendants           Sort by:
rac-3,4-methylenedioxy-N-ethylamphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO 3,4-methylenedioxyethamphetamine results in decreased activity of ABCB1 protein CTD PMID:14690877 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Comt catechol-O-methyltransferase increases methylation
multiple interactions
ISO COMT protein alternative form results in increased methylation of 3,4-methylenedioxyethamphetamine
3,4-methylenedioxyethamphetamine inhibits the reaction [COMT protein results in increased methylation of Dopamine]
CTD PMID:19462939 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    chemical entity 19795
      chemical substance 13189
        mixture 12396
          racemate 10479
            rac-3,4-methylenedioxy-N-ethylamphetamine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    main group molecular entity 19693
                      s-block molecular entity 19474
                        hydrogen molecular entity 19466
                          hydrides 18830
                            inorganic hydride 17688
                              pnictogen hydride 17668
                                nitrogen hydride 17540
                                  azane 17273
                                    ammonia 17272
                                      organic amino compound 17272
                                        secondary amino compound 6631
                                          1-(1,3-benzodioxol-5-yl)-N-ethylpropan-2-amine 2
                                            (R)-3,4-methylenedioxy-N-ethylamphetamine 2
                                              rac-3,4-methylenedioxy-N-ethylamphetamine 2
paths to the root