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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:132237 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-3,4-methylenedioxy-N-ethylamphetamine3,4-methylenedioxy-N-ethylamphetamine.
Synonyms:related_synonym: 3,4-methylenedioxy-N-ethylamphetamine;   Eve;   MDE;   MDEA;   N-ethyl MDA;   N-ethyl-alpha-methyl-3,4-(methylenedioxy)phenethylamine
 xref: CAS:82801-81-8;   DrugBank:DB01566
 xref_mesh: MESH:C051800
 xref: PMID:10533279;   PMID:10672974;   PMID:15179441;   PMID:19007498;   PMID:22564759;   PMID:24970379;   PMID:25029504;   PMID:25933611;   PMID:26538543;   PMID:26654084;   PMID:26829334;   PMID:26888521;   PMID:8563033;   PMID:8735473;   PMID:9549899;   Reaxys:4184143;   Wikipedia:Methylenedioxyethylamphetamine

show annotations for term's descendants           Sort by:
rac-3,4-methylenedioxy-N-ethylamphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO 3,4-methylenedioxyethamphetamine results in decreased activity of ABCB1 protein CTD PMID:14690877 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Comt catechol-O-methyltransferase increases methylation
multiple interactions
ISO COMT protein alternative form results in increased methylation of 3,4-methylenedioxyethamphetamine
3,4-methylenedioxyethamphetamine inhibits the reaction [COMT protein results in increased methylation of Dopamine]
CTD PMID:19462939 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      chemical substance 11926
        mixture 10843
          racemate 9739
            rac-3,4-methylenedioxy-N-ethylamphetamine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    main group molecular entity 19670
                      s-block molecular entity 19428
                        hydrogen molecular entity 19418
                          hydrides 18685
                            inorganic hydride 17409
                              pnictogen hydride 17381
                                nitrogen hydride 17223
                                  azane 16940
                                    ammonia 16939
                                      organic amino compound 16938
                                        secondary amino compound 6515
                                          1-(1,3-benzodioxol-5-yl)-N-ethylpropan-2-amine 2
                                            (R)-3,4-methylenedioxy-N-ethylamphetamine 2
                                              rac-3,4-methylenedioxy-N-ethylamphetamine 2
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.