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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(R)-3,4-methylenedioxy-N-ethylamphetamine
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Accession:CHEBI:132235 term browser browse the term
Definition:A 1-(1,3-benzodioxol-5-yl)-N-ethylpropan-2-amine that has formula C12H17NO2.
Synonyms:cyclic_relationship: is_enantiomer_of CHEBI:132236



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rac-3,4-methylenedioxy-N-ethylamphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 decreases activity EXP 3,4-methylenedioxyethamphetamine results in decreased activity of ABCB1 protein CTD PMID:14690877 NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
JBrowse link
G COMT catechol-O-methyltransferase increases methylation
multiple interactions
EXP COMT protein alternative form results in increased methylation of 3,4-methylenedioxyethamphetamine
3,4-methylenedioxyethamphetamine inhibits the reaction [COMT protein results in increased methylation of Dopamine]
CTD PMID:19462939 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26034
    role 25961
      application 25172
        NMR chemical shift reference compound 20287
          ammonia 19941
            organic amino compound 19941
              secondary amino compound 6948
                1-(1,3-benzodioxol-5-yl)-N-ethylpropan-2-amine 2
                  (R)-3,4-methylenedioxy-N-ethylamphetamine 2
                    rac-3,4-methylenedioxy-N-ethylamphetamine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 26034
    subatomic particle 26009
      composite particle 26009
        hadron 26020
          baryon 26009
            nucleon 26009
              atomic nucleus 26009
                atom 26009
                  main group element atom 25834
                    main group molecular entity 25834
                      s-block molecular entity 25166
                        hydrogen molecular entity 24765
                          hydrides 22965
                            inorganic hydride 20483
                              pnictogen hydride 20424
                                nitrogen hydride 20200
                                  azane 19942
                                    ammonia 19941
                                      organic amino compound 19941
                                        amine 8471
                                          amphetamines 5778
                                            (R)-3,4-methylenedioxy-N-ethylamphetamine 2
                                              rac-3,4-methylenedioxy-N-ethylamphetamine 2
paths to the root