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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:6-carboxyfluorescein succinimidyl ester
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Accession:CHEBI:132203 term browser browse the term
Definition:An N-hydroxysuccinimide ester derived from 6-carboxyfluorescein. A fluorescent cell staining dye, it is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably to intracellular lysine residues.
Synonyms:exact_synonym: 1-[(3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-6-carbonyl)oxy]pyrrolidine-2,5-dione
 related_synonym: 1-[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl)carbonyl]oxy]-2,5-pyrrolidinedione;   CFSE;   Formula=C25H15NO9;   InChI=1S/C25H15NO9/c27-13-2-5-16-19(10-13)33-20-11-14(28)3-6-17(20)25(16)18-9-12(1-4-15(18)24(32)34-25)23(31)35-26-21(29)7-8-22(26)30/h1-6,9-11,27-28H,7-8H2;   InChIKey=VDABVNMGKGUPEY-UHFFFAOYSA-N;   OSu-FAM;   SMILES=C12=CC(=CC=C2C3(C=4C=CC(=CC4O1)O)C=5C=C(C=CC5C(O3)=O)C(ON6C(CCC6=O)=O)=O)O;   carboxyfluorescein N-hydroxysuccinimide ester;   carboxyfluorescein succinimidyl ester
 xref: PMID:10571670;   PMID:2212694;   PMID:8691143;   PMID:9221753;   PMID:9689107;   PMID:9729043;   Reaxys:8024096;   Wikipedia:Carboxyfluorescein_succinimidyl_ester


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Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      application 19650
        dye 2975
          xanthene dye 88
            fluorescein (lactone form) 68
              6-carboxyfluorescein succinimidyl ester 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            heteroorganic entity 19477
                              organochalcogen compound 19240
                                organooxygen compound 19155
                                  carbon oxoacid 18613
                                    carboxylic acid 18610
                                      aromatic carboxylic acid 12594
                                        benzoic acids 12571
                                          fluorescein (acid form) 69
                                            fluorescein (lactone form) 68
                                              6-carboxyfluorescein succinimidyl ester 0
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