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ONTOLOGY REPORT - ANNOTATIONS


Term:hydroxy-1,4-naphthoquinone
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Accession:CHEBI:132157 term browser browse the term
Definition:Any member of the class of 1,4-naphthoquinones in which the naphthoquinone moiety is substituted by at least one hydroxy group.
Synonyms:related_synonym: hydroxy-1,4-naphthoquinones


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Alkannin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Mpo myeloperoxidase JBrowse link 11 87,793,784 87,804,412 RGD:6480464
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Rho rhodopsin JBrowse link 6 115,926,754 115,940,038 RGD:6480464
G Rock1 Rho-associated coiled-coil containing protein kinase 1 JBrowse link 18 10,064,401 10,182,251 RGD:6480464
G Rock2 Rho-associated coiled-coil containing protein kinase 2 JBrowse link 12 16,894,978 16,988,274 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
atovaquone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Dhodh dihydroorotate dehydrogenase JBrowse link 8 109,593,244 109,608,699 RGD:6480464
G Gstp1 glutathione S-transferase, pi 1 JBrowse link 19 4,035,411 4,037,912 RGD:6480464
juglone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl-hydrocarbon receptor JBrowse link 12 35,497,979 35,534,989 RGD:6480464
G Bad BCL2-associated agonist of cell death JBrowse link 19 6,941,861 6,951,905 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bid BH3 interacting domain death agonist JBrowse link 6 120,893,119 120,917,062 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp8 caspase 8 JBrowse link 1 58,795,233 58,847,503 RGD:6480464
G Cat catalase JBrowse link 2 103,453,904 103,485,153 RGD:6480464
G Ccnd3 cyclin D3 JBrowse link 17 47,505,051 47,599,689 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 10 127,063,535 127,067,288 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Dhodh dihydroorotate dehydrogenase JBrowse link 8 109,593,244 109,608,699 RGD:6480464
G E2f4 E2F transcription factor 4 JBrowse link 8 105,297,663 105,305,370 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 34,861,207 34,864,956 RGD:6480464
G Gsr glutathione reductase JBrowse link 8 33,653,238 33,698,162 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 8 121,590,438 121,598,760 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 8 92,827,290 92,853,421 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:6480464
G Pin1 protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 JBrowse link 9 20,652,118 20,663,712 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 7 142,892,779 142,899,995 RGD:6480464
G Timp1 tissue inhibitor of metalloproteinase 1 JBrowse link X 20,870,166 20,874,737 RGD:6480464
G Timp2 tissue inhibitor of metalloproteinase 2 JBrowse link 11 118,301,061 118,355,411 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 10 82,833,951 82,897,724 RGD:6480464
G Txnrd2 thioredoxin reductase 2 JBrowse link 16 18,426,417 18,479,073 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464
Lapachol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dhodh dihydroorotate dehydrogenase JBrowse link 8 109,593,244 109,608,699 RGD:6480464
lawsone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl-hydrocarbon receptor JBrowse link 12 35,497,979 35,534,989 RGD:6480464
G Dhodh dihydroorotate dehydrogenase JBrowse link 8 109,593,244 109,608,699 RGD:6480464
G Nqo1 NAD(P)H dehydrogenase, quinone 1 JBrowse link 8 107,388,225 107,403,205 RGD:6480464
naphthazarin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Dhodh dihydroorotate dehydrogenase JBrowse link 8 109,593,244 109,608,699 RGD:6480464
plumbagin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp8 caspase 8 JBrowse link 1 58,795,233 58,847,503 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Ctrl chymotrypsin-like JBrowse link 8 105,931,994 105,933,862 RGD:6480464
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 10 127,290,793 127,296,291 RGD:6480464
G Dhodh dihydroorotate dehydrogenase JBrowse link 8 109,593,244 109,608,699 RGD:6480464
G Fas Fas (TNF receptor superfamily member 6) JBrowse link 19 34,290,647 34,327,775 RGD:6480464
G G6pc glucose-6-phosphatase, catalytic JBrowse link 11 101,367,716 101,377,903 RGD:6480464
G Gclm glutamate-cysteine ligase, modifier subunit JBrowse link 3 122,245,487 122,267,215 RGD:6480464
G Gstp1 glutathione S-transferase, pi 1 JBrowse link 19 4,035,411 4,037,912 RGD:6480464
G Hk1 hexokinase 1 JBrowse link 10 62,268,855 62,379,920 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:6480464
G Hspa5 heat shock protein 5 JBrowse link 2 34,772,090 34,776,529 RGD:6480464
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Nqo1 NAD(P)H dehydrogenase, quinone 1 JBrowse link 8 107,388,225 107,403,205 RGD:6480464
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 67,665,501 67,724,632 RGD:6480464
G Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 JBrowse link 11 69,942,286 69,948,216 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 11 50,200,152 50,210,820 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 10 82,833,951 82,897,724 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 JBrowse link 1 88,211,959 88,220,002 RGD:6480464
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 JBrowse link 1 88,055,411 88,220,002 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 JBrowse link 1 88,070,779 88,220,002 RGD:6480464
Shikonin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin, alpha 2, smooth muscle, aorta JBrowse link 19 34,240,336 34,255,585 RGD:6480464
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 1 191,170,296 191,183,333 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Ccl1 chemokine (C-C motif) ligand 1 JBrowse link 11 82,176,666 82,179,812 RGD:6480464
G Ccl4 chemokine (C-C motif) ligand 4 JBrowse link 11 83,648,624 83,664,683 RGD:6480464
G Ccl7 chemokine (C-C motif) ligand 7 JBrowse link 11 82,045,712 82,047,525 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 7 144,929,931 144,939,831 RGD:6480464
G Ccne1 cyclin E1 JBrowse link 7 38,097,984 38,107,490 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:6480464
G Col1a1 collagen, type I, alpha 1 JBrowse link 11 94,936,224 94,953,042 RGD:6480464
G Col3a1 collagen, type III, alpha 1 JBrowse link 1 45,311,538 45,349,706 RGD:6480464
G Csf1 colony stimulating factor 1 (macrophage) JBrowse link 3 107,741,048 107,760,469 RGD:6480464
G Csrnp1 cysteine-serine-rich nuclear protein 1 JBrowse link 9 119,971,163 119,984,742 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 JBrowse link 7 25,897,658 25,926,624 RGD:6480464
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene JBrowse link 19 38,976,662 39,003,627 RGD:6480464
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 JBrowse link 19 39,061,006 39,093,948 RGD:6480464
G Cyp2c66 cytochrome P450, family 2, subfamily c, polypeptide 66 JBrowse link 19 39,113,898 39,186,756 RGD:6480464
G Cyp2d10 cytochrome P450, family 2, subfamily d, polypeptide 10 JBrowse link 15 82,402,845 82,407,253 RGD:6480464
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 JBrowse link 15 82,370,527 82,380,260 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 7 140,763,819 140,774,990 RGD:6480464
G Dusp1 dual specificity phosphatase 1 JBrowse link 17 26,505,591 26,508,472 RGD:6480464
G Dusp6 dual specificity phosphatase 6 JBrowse link 10 99,263,231 99,267,489 RGD:6480464
G Egr2 early growth response 2 JBrowse link 10 67,534,469 67,542,188 RGD:6480464
G Egr3 early growth response 3 JBrowse link 14 70,077,317 70,082,613 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 8 27,260,327 27,275,656 RGD:6480464
G Fos FBJ osteosarcoma oncogene JBrowse link 12 85,473,890 85,477,274 RGD:6480464
G Fosb FBJ osteosarcoma oncogene B JBrowse link 7 19,302,696 19,310,118 RGD:6480464
G Hif1a hypoxia inducible factor 1, alpha subunit JBrowse link 12 73,901,324 73,947,554 RGD:6480464
G Il13 interleukin 13 JBrowse link 11 53,631,323 53,634,702 RGD:6480464
G Itgb1 integrin beta 1 (fibronectin receptor beta) JBrowse link 8 128,685,654 128,733,579 RGD:6480464
G Jun jun proto-oncogene JBrowse link 4 95,049,036 95,052,222 RGD:6480464
G Map3k8 mitogen-activated protein kinase kinase kinase 8 JBrowse link 18 4,331,325 4,352,953 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Mt2 metallothionein 2 JBrowse link 8 94,172,618 94,173,567 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 4 148,448,582 148,557,685 RGD:6480464
G Nfkbid nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta JBrowse link 7 30,421,731 30,428,749 RGD:6480464
G Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta JBrowse link 16 55,811,375 55,838,954 RGD:6480464
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 JBrowse link 15 101,253,902 101,274,795 RGD:6480464
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 JBrowse link 2 57,106,830 57,124,003 RGD:6480464
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 4 48,045,078 48,086,447 RGD:6480464
G Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 JBrowse link 6 129,479,150 129,507,350 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 2 132,249,286 132,253,180 RGD:6480464
G Plk3 polo like kinase 3 JBrowse link 4 117,128,655 117,133,963 RGD:6480464
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 7 45,522,917 45,526,268 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 JBrowse link 13 34,002,225 34,035,170 RGD:6480464
G Ripk3 receptor-interacting serine-threonine kinase 3 JBrowse link 14 55,784,995 55,788,857 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 JBrowse link 11 86,498,869 86,544,885 RGD:6480464
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 JBrowse link 5 137,061,504 137,072,272 RGD:6480464
G Tagap T cell activation Rho GTPase activating protein JBrowse link 17 7,926,000 7,934,897 RGD:6480464
G Tagap1 T cell activation GTPase activating protein 1 JBrowse link 17 6,954,965 6,961,565 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 JBrowse link 1 88,211,959 88,220,002 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 1 88,200,611 88,220,002 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 JBrowse link 1 88,070,779 88,220,002 RGD:6480464
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 JBrowse link 5 86,889,770 86,906,937 RGD:6480464
G Zfp36 zinc finger protein 36 JBrowse link 7 28,376,784 28,379,228 RGD:6480464
G Zfp36l1 zinc finger protein 36, C3H type-like 1 JBrowse link 12 80,107,760 80,113,013 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21260
    chemical entity 21258
      molecular entity 21251
        polyatomic entity 21130
          heteroatomic molecular entity 21037
            hydroxides 19767
              organic hydroxy compound 18879
                hydroxyquinone 169
                  hydroxynaphthoquinone 112
                    hydroxy-1,4-naphthoquinone 112
                      2,6,7-trihydroxy-3-methylnaphthalene-1,4-dione 0
                      2,8-dihydroxy-1,4-naphthoquinone 0
                      2-O,3-dimethylflaviolin 0
                      2-hydroxy-3-(2-hydroxyethyl)naphthalene-1,4-dione 0
                      3-linalylflaviolin 0
                      6-linalyl-2-O,3-dimethylflaviolin 0
                      7-O-geranyl-2-O,3-dimethylflaviolin 0
                      Acetylshikonin 0
                      Alkannin 9
                      Alkannin beta,beta-dimethylacrylate 0
                      Aristolindiquinone 0
                      Deoxyshikonin 0
                      Diospyrin 0
                      Droserone 0
                      Echinone 0
                      Hypoxylone 0
                      Isobutylshikonin 0
                      Lapachol 1
                      Ramentaceone 0
                      Shikonin 64
                      Tricrozarin A 0
                      atovaquone 3
                      aureoquinone 0
                      beta,beta-Dimethylacrylshikonin 0
                      flaviolin + 0
                      hypocrellin D 0
                      impatienol 0
                      juglone 29
                      lawsone 3
                      naphthazarin 2
                      phosphatoquinone B 0
                      plumbagin 26
                      rhinacanthin C 0
                      rhinacanthin D 0
                      rifamycin-undecaketide carboxylic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 21260
    subatomic particle 21256
      composite particle 21256
        hadron 21256
          baryon 21256
            nucleon 21256
              atomic nucleus 21256
                atom 21256
                  main group element atom 21125
                    p-block element atom 21125
                      carbon group element atom 20894
                        carbon atom 20785
                          organic molecular entity 20785
                            organic group 19179
                              organic divalent group 19169
                                organodiyl group 19169
                                  carbonyl group 19143
                                    carbonyl compound 19143
                                      ketone 16297
                                        cyclic ketone 13609
                                          quinone 8375
                                            naphthoquinone 1436
                                              1,4-naphthoquinones 1412
                                                hydroxy-1,4-naphthoquinone 112
                                                  2,6,7-trihydroxy-3-methylnaphthalene-1,4-dione 0
                                                  2,8-dihydroxy-1,4-naphthoquinone 0
                                                  2-O,3-dimethylflaviolin 0
                                                  2-hydroxy-3-(2-hydroxyethyl)naphthalene-1,4-dione 0
                                                  3-linalylflaviolin 0
                                                  6-linalyl-2-O,3-dimethylflaviolin 0
                                                  7-O-geranyl-2-O,3-dimethylflaviolin 0
                                                  Acetylshikonin 0
                                                  Alkannin 9
                                                  Alkannin beta,beta-dimethylacrylate 0
                                                  Aristolindiquinone 0
                                                  Deoxyshikonin 0
                                                  Diospyrin 0
                                                  Droserone 0
                                                  Echinone 0
                                                  Hypoxylone 0
                                                  Isobutylshikonin 0
                                                  Lapachol 1
                                                  Ramentaceone 0
                                                  Shikonin 64
                                                  Tricrozarin A 0
                                                  atovaquone 3
                                                  aureoquinone 0
                                                  beta,beta-Dimethylacrylshikonin 0
                                                  flaviolin + 0
                                                  hypocrellin D 0
                                                  impatienol 0
                                                  juglone 29
                                                  lawsone 3
                                                  naphthazarin 2
                                                  phosphatoquinone B 0
                                                  plumbagin 26
                                                  rhinacanthin C 0
                                                  rhinacanthin D 0
                                                  rifamycin-undecaketide carboxylic acid + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.