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ONTOLOGY REPORT - ANNOTATIONS


Term:hydroxy-1,4-naphthoquinone
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Accession:CHEBI:132157 term browser browse the term
Definition:Any member of the class of 1,4-naphthoquinones in which the naphthoquinone moiety is substituted by at least one hydroxy group.
Synonyms:related_synonym: hydroxy-1,4-naphthoquinones


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Alkannin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G MPO myeloperoxidase JBrowse link 17 58,269,855 58,280,935 RGD:6480464
G NFKBIA NFKB inhibitor alpha JBrowse link 14 35,401,513 35,404,749 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G RHO rhodopsin JBrowse link 3 129,528,639 129,535,344 RGD:6480464
G ROCK1 Rho associated coiled-coil containing protein kinase 1 JBrowse link 18 20,946,906 21,111,813 RGD:6480464
G ROCK2 Rho associated coiled-coil containing protein kinase 2 JBrowse link 2 11,179,759 11,345,437 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
atovaquone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 15 74,748,845 74,756,607 RGD:6480464
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 16 72,008,744 72,027,659 RGD:6480464
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 67,583,812 67,586,653 RGD:6480464
juglone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AHR aryl hydrocarbon receptor JBrowse link 7 17,298,652 17,346,147 RGD:6480464
G BAD BCL2 associated agonist of cell death JBrowse link 11 64,269,828 64,284,704 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BID BH3 interacting domain death agonist JBrowse link 22 17,734,138 17,774,665 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP8 caspase 8 JBrowse link 2 201,233,443 201,287,711 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CCND3 cyclin D3 JBrowse link 6 41,934,933 42,048,894 RGD:6480464
G CDK4 cyclin dependent kinase 4 JBrowse link 12 57,747,727 57,752,310 RGD:6480464
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 15 74,719,542 74,725,528 RGD:6480464
G DAB2 DAB adaptor protein 2 JBrowse link 5 39,371,674 39,425,233 RGD:6480464
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 16 72,008,744 72,027,659 RGD:6480464
G E2F4 E2F transcription factor 4 JBrowse link 16 67,192,155 67,198,918 RGD:6480464
G EGR1 early growth response 1 JBrowse link 5 138,465,479 138,469,303 RGD:6480464
G GSR glutathione-disulfide reductase JBrowse link 8 30,678,061 30,727,999 RGD:6480464
G MAP1LC3B microtubule associated protein 1 light chain 3 beta JBrowse link 16 87,392,336 87,404,774 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MMP2 matrix metallopeptidase 2 JBrowse link 16 55,478,830 55,506,691 RGD:6480464
G MMP9 matrix metallopeptidase 9 JBrowse link 20 46,008,908 46,016,561 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 JBrowse link 19 9,835,207 9,849,689 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G TH tyrosine hydroxylase JBrowse link 11 2,163,929 2,174,081 RGD:6480464
G TIMP1 TIMP metallopeptidase inhibitor 1 JBrowse link X 47,582,408 47,586,789 RGD:6480464
G TIMP2 TIMP metallopeptidase inhibitor 2 JBrowse link 17 78,852,977 78,925,387 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464
G TXNRD1 thioredoxin reductase 1 JBrowse link 12 104,215,779 104,350,307 RGD:6480464
G TXNRD2 thioredoxin reductase 2 JBrowse link 22 19,875,518 19,941,818 RGD:6480464
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:6480464
Lapachol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 16 72,008,744 72,027,659 RGD:6480464
lawsone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AHR aryl hydrocarbon receptor JBrowse link 7 17,298,652 17,346,147 RGD:6480464
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 16 72,008,744 72,027,659 RGD:6480464
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,709,401 69,726,560 RGD:6480464
naphthazarin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 15 74,719,542 74,725,528 RGD:6480464
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 16 72,008,744 72,027,659 RGD:6480464
plumbagin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP8 caspase 8 JBrowse link 2 201,233,443 201,287,711 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CTRL chymotrypsin like JBrowse link 16 67,929,574 67,931,862 RGD:6480464
G DDIT3 DNA damage inducible transcript 3 JBrowse link 12 57,516,588 57,520,517 RGD:6480464
G DHODH dihydroorotate dehydrogenase (quinone) JBrowse link 16 72,008,744 72,027,659 RGD:6480464
G FAS Fas cell surface death receptor JBrowse link 10 88,968,429 89,017,059 RGD:6480464
G G6PC glucose-6-phosphatase catalytic subunit JBrowse link 17 42,900,799 42,914,438 RGD:6480464
G GCLM glutamate-cysteine ligase modifier subunit JBrowse link 1 93,885,199 93,910,370 RGD:6480464
G GSTP1 glutathione S-transferase pi 1 JBrowse link 11 67,583,812 67,586,653 RGD:6480464
G HK1 hexokinase 1 JBrowse link 10 69,269,991 69,401,882 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G HSPA5 heat shock protein family A (Hsp70) member 5 JBrowse link 9 125,234,853 125,241,343 RGD:6480464
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,709,401 69,726,560 RGD:6480464
G PTPN2 protein tyrosine phosphatase non-receptor type 2 JBrowse link 18 12,785,478 12,884,351 RGD:6480464
G SLC2A4 solute carrier family 2 member 4 JBrowse link 17 7,281,718 7,288,257 RGD:6480464
G SQSTM1 sequestosome 1 JBrowse link 5 179,806,393 179,838,078 RGD:6480464
G TXNRD1 thioredoxin reductase 1 JBrowse link 12 104,215,779 104,350,307 RGD:6480464
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 2 233,760,270 233,773,300 RGD:6480464
G UGT1A10 UDP glucuronosyltransferase family 1 member A10 JBrowse link 2 233,636,477 233,773,305 RGD:6480464
G UGT1A7 UDP glucuronosyltransferase family 1 member A7 JBrowse link 2 233,681,938 233,773,299 RGD:6480464
G UGT1A8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 2 233,617,645 233,773,299 RGD:6480464
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 2 233,671,898 233,773,300 RGD:6480464
Shikonin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACTA2 actin alpha 2, smooth muscle JBrowse link 10 88,935,074 88,991,397 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G ATF3 activating transcription factor 3 JBrowse link 1 212,565,334 212,620,777 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CCL1 C-C motif chemokine ligand 1 JBrowse link 17 34,360,328 34,363,233 RGD:6480464
G CCL4 C-C motif chemokine ligand 4 JBrowse link 17 36,103,827 36,105,614 RGD:6480464
G CCL7 C-C motif chemokine ligand 7 JBrowse link 17 34,270,221 34,272,242 RGD:6480464
G CCND1 cyclin D1 JBrowse link 11 69,641,156 69,654,474 RGD:6480464
G CCNE1 cyclin E1 JBrowse link 19 29,811,991 29,824,312 RGD:6480464
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 36,676,463 36,687,332 RGD:6480464
G COL1A1 collagen type I alpha 1 chain JBrowse link 17 50,184,096 50,201,649 RGD:6480464
G COL3A1 collagen type III alpha 1 chain JBrowse link 2 188,974,373 189,012,746 RGD:6480464
G CSF1 colony stimulating factor 1 JBrowse link 1 109,910,506 109,930,992 RGD:6480464
G CSRNP1 cysteine and serine rich nuclear protein 1 JBrowse link 3 39,141,851 39,154,641 RGD:6480464
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 15 74,748,845 74,756,607 RGD:6480464
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 JBrowse link 19 40,991,282 41,018,398 RGD:6480464
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 JBrowse link 10 94,938,658 94,990,091 RGD:6480464
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 JBrowse link 22 42,126,499 42,130,810 RGD:6480464
G CYP2D7 cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) JBrowse link 22 42,139,576 42,144,483 RGD:6480464
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 JBrowse link 10 133,527,363 133,539,123 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G DUSP1 dual specificity phosphatase 1 JBrowse link 5 172,768,096 172,771,195 RGD:6480464
G DUSP6 dual specificity phosphatase 6 JBrowse link 12 89,347,235 89,352,501 RGD:6480464
G EGR2 early growth response 2 JBrowse link 10 62,811,996 62,819,167 RGD:6480464
G EGR3 early growth response 3 JBrowse link 8 22,687,659 22,693,480 RGD:6480464
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 8 38,030,534 38,060,365 RGD:6480464
G FOS Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 14 75,278,828 75,282,230 RGD:6480464
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit JBrowse link 19 45,467,996 45,475,179 RGD:6480464
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 61,695,513 61,748,259 RGD:6480464
G IL13 interleukin 13 JBrowse link 5 132,656,522 132,661,110 RGD:6480464
G ITGB1 integrin subunit beta 1 JBrowse link 10 32,900,318 32,958,230 RGD:6480464
G JUN Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 58,780,791 58,784,047 RGD:6480464
G MAP3K8 mitogen-activated protein kinase kinase kinase 8 JBrowse link 10 30,434,021 30,461,833 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MT2A metallothionein 2A JBrowse link 16 56,608,584 56,609,497 RGD:6480464
G MTOR mechanistic target of rapamycin kinase JBrowse link 1 11,106,535 11,273,497 RGD:6480464
G NFKBID NFKB inhibitor delta JBrowse link 19 35,887,630 35,902,303 RGD:6480464
G NFKBIZ NFKB inhibitor zeta JBrowse link 3 101,827,990 101,861,022 RGD:6480464
G NR4A1 nuclear receptor subfamily 4 group A member 1 JBrowse link 12 52,022,832 52,059,507 RGD:6480464
G NR4A2 nuclear receptor subfamily 4 group A member 2 JBrowse link 2 156,324,432 156,332,724 RGD:6480464
G NR4A3 nuclear receptor subfamily 4 group A member 3 JBrowse link 9 99,821,855 99,866,893 RGD:6480464
G OLR1 oxidized low density lipoprotein receptor 1 JBrowse link 12 10,158,300 10,172,191 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PCNA proliferating cell nuclear antigen JBrowse link 20 5,114,953 5,126,622 RGD:6480464
G PLK3 polo like kinase 3 JBrowse link 1 44,799,952 44,805,995 RGD:6480464
G PPP1R15A protein phosphatase 1 regulatory subunit 15A JBrowse link 19 48,872,392 48,876,062 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G RIPK1 receptor interacting serine/threonine kinase 1 JBrowse link 6 3,063,967 3,115,187 RGD:6480464
G RIPK3 receptor interacting serine/threonine kinase 3 JBrowse link 14 24,336,025 24,339,991 RGD:6480464
G RPS6KB1 ribosomal protein S6 kinase B1 JBrowse link 17 59,893,046 59,950,574 RGD:6480464
G SERPINE1 serpin family E member 1 JBrowse link 7 101,127,104 101,139,247 RGD:6480464
G TAGAP T cell activation RhoGTPase activating protein JBrowse link 6 159,034,468 159,045,152 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464
G UGT1A1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 2 233,760,270 233,773,300 RGD:6480464
G UGT1A3 UDP glucuronosyltransferase family 1 member A3 JBrowse link 2 233,729,042 233,773,300 RGD:6480464
G UGT1A9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 2 233,671,898 233,773,300 RGD:6480464
G UGT2B7 UDP glucuronosyltransferase family 2 member B7 JBrowse link 4 69,051,264 69,112,987 RGD:6480464
G ZFP36 ZFP36 ring finger protein JBrowse link 19 39,406,847 39,409,407 RGD:6480464
G ZFP36L1 ZFP36 ring finger protein like 1 JBrowse link 14 68,787,655 68,796,243 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23909
    chemical entity 23872
      molecular entity 23821
        polyatomic entity 23730
          heteroatomic molecular entity 23321
            hydroxides 22145
              organic hydroxy compound 20533
                hydroxyquinone 171
                  hydroxynaphthoquinone 113
                    hydroxy-1,4-naphthoquinone 113
                      2,6,7-trihydroxy-3-methylnaphthalene-1,4-dione 0
                      2,8-dihydroxy-1,4-naphthoquinone 0
                      2-O,3-dimethylflaviolin 0
                      2-hydroxy-3-(2-hydroxyethyl)naphthalene-1,4-dione 0
                      3-linalylflaviolin 0
                      6-linalyl-2-O,3-dimethylflaviolin 0
                      7-O-geranyl-2-O,3-dimethylflaviolin 0
                      Acetylshikonin 0
                      Alkannin 9
                      Alkannin beta,beta-dimethylacrylate 0
                      Aristolindiquinone 0
                      Deoxyshikonin 0
                      Diospyrin 0
                      Droserone 0
                      Echinone 0
                      Hypoxylone 0
                      Isobutylshikonin 0
                      Lapachol 1
                      Ramentaceone 0
                      Shikonin 62
                      Tricrozarin A 0
                      atovaquone 3
                      aureoquinone 0
                      beta,beta-Dimethylacrylshikonin 0
                      flaviolin + 0
                      hypocrellin D 0
                      impatienol 0
                      juglone 30
                      lawsone 3
                      naphthazarin 2
                      phosphatoquinone B 0
                      plumbagin 28
                      rhinacanthin C 0
                      rhinacanthin D 0
                      rifamycin-undecaketide carboxylic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23909
    subatomic particle 23860
      composite particle 23860
        hadron 23860
          baryon 23860
            nucleon 23860
              atomic nucleus 23860
                atom 23860
                  main group element atom 23681
                    p-block element atom 23681
                      carbon group element atom 23401
                        carbon atom 23358
                          organic molecular entity 23358
                            organic group 22026
                              organic divalent group 22000
                                organodiyl group 22000
                                  carbonyl group 21975
                                    carbonyl compound 21975
                                      ketone 18064
                                        cyclic ketone 14520
                                          quinone 8833
                                            naphthoquinone 1472
                                              1,4-naphthoquinones 1448
                                                hydroxy-1,4-naphthoquinone 113
                                                  2,6,7-trihydroxy-3-methylnaphthalene-1,4-dione 0
                                                  2,8-dihydroxy-1,4-naphthoquinone 0
                                                  2-O,3-dimethylflaviolin 0
                                                  2-hydroxy-3-(2-hydroxyethyl)naphthalene-1,4-dione 0
                                                  3-linalylflaviolin 0
                                                  6-linalyl-2-O,3-dimethylflaviolin 0
                                                  7-O-geranyl-2-O,3-dimethylflaviolin 0
                                                  Acetylshikonin 0
                                                  Alkannin 9
                                                  Alkannin beta,beta-dimethylacrylate 0
                                                  Aristolindiquinone 0
                                                  Deoxyshikonin 0
                                                  Diospyrin 0
                                                  Droserone 0
                                                  Echinone 0
                                                  Hypoxylone 0
                                                  Isobutylshikonin 0
                                                  Lapachol 1
                                                  Ramentaceone 0
                                                  Shikonin 62
                                                  Tricrozarin A 0
                                                  atovaquone 3
                                                  aureoquinone 0
                                                  beta,beta-Dimethylacrylshikonin 0
                                                  flaviolin + 0
                                                  hypocrellin D 0
                                                  impatienol 0
                                                  juglone 30
                                                  lawsone 3
                                                  naphthazarin 2
                                                  phosphatoquinone B 0
                                                  plumbagin 28
                                                  rhinacanthin C 0
                                                  rhinacanthin D 0
                                                  rifamycin-undecaketide carboxylic acid + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.