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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:resolvin
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Accession:CHEBI:132120 term browser browse the term
Definition:Hydroxy fatty acids that are di- or trihydroxy metabolites of the polyunsaturated omega-3 fatty acids, particularly icosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid.
Synonyms:related_synonym: resolution phase interaction product;   resolution phase interaction products;   resolvins
 xref: PMID:25359497;   PMID:26546247;   PMID:26986653;   Wikipedia:Resolvin


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resolvin D1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO resolvin D1 inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]; t-butyloxycarbonyl-methionyl-leucyl-phenylalanine inhibits the reaction [resolvin D1 inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]] CTD PMID:21724996 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 protein] CTD PMID:21724996 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL1 protein] CTD PMID:21724996 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat results in decreased expression of GPX1 mRNA] CTD PMID:30562684 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; resolvin D1 inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA] CTD PMID:30562684 PMID:30571954 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA] CTD PMID:21724996 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions ISO resolvin D1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein]; t-butyloxycarbonyl-methionyl-leucyl-phenylalanine inhibits the reaction [resolvin D1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein]] CTD PMID:21724996 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat results in increased expression of IL1B protein]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein] CTD PMID:21724996 PMID:30562684 PMID:30571954 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO resolvin D1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; t-butyloxycarbonyl-methionyl-leucyl-phenylalanine inhibits the reaction [resolvin D1 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]] CTD PMID:21724996 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgal integrin subunit alpha L multiple interactions ISO resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of ITGAL mRNA] CTD PMID:21724996 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat results in increased activity of MPO protein]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; resolvin D1 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:21724996 PMID:30562684 PMID:30571954 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat affects the localization of NFE2L2 protein]; resolvin D1 inhibits the reaction [Paraquat affects the localization of NFE2L2 protein]; resolvin D1 inhibits the reaction [Paraquat results in decreased expression of NFE2L2 mRNA] CTD PMID:30562684 PMID:30571954 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of NFKBIA mRNA] CTD PMID:21724996 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat results in decreased expression of NQO1 mRNA] CTD PMID:30562684 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO resolvin D1 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21724996 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat results in increased phosphorylation of RELA protein]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased activity of RELA protein] CTD PMID:21724996 PMID:30562684 PMID:30571954 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Selp selectin P multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat results in increased expression of SELP protein] CTD PMID:30562684 PMID:30571954 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat results in decreased expression of SOD1 mRNA] CTD PMID:30562684 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO resolvin D1 analog inhibits the reaction [Paraquat results in increased expression of TNF protein]; resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; resolvin D1 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; t-butyloxycarbonyl-methionyl-leucyl-phenylalanine inhibits the reaction [resolvin D1 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]] CTD PMID:21724996 PMID:30562684 PMID:30571954 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO resolvin D1 inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA] CTD PMID:21724996 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
resolvin D2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein] CTD PMID:21724996 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL2 protein] CTD PMID:21724996 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of CXCL1 protein] CTD PMID:21724996 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of ICAM1 mRNA] CTD PMID:21724996 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Ifng interferon gamma multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of IFNG protein] CTD PMID:21724996 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein] CTD PMID:21724996 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:21724996 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Itgal integrin subunit alpha L multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of ITGAL mRNA] CTD PMID:21724996 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein]; resolvin D2 inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:21724996 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of NFKBIA mRNA] CTD PMID:21724996 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21724996 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased activity of RELA protein] CTD PMID:21724996 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]; resolvin D2 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:21724996 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO resolvin D2 inhibits the reaction [Dextran Sulfate results in increased expression of VCAM1 mRNA] CTD PMID:21724996 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    role 19769
      biological role 19769
        specialised pro-resolving mediator 37
          resolvin 20
            (18R)-resolvin E3 0
            (18S)-resolvin E1 0
            (18S)-resolvin E2 0
            (6Z,8E,10E,14Z,16E,18R)-5,12,18-trihydroxyicosapentaenoic acid 0
            16-oxoresolvin D2 0
            17-oxoresolvin D1 0
            7-oxoresolvin D2 0
            8-oxoresolvin D1 0
            aspirin-triggered resolvin D1 0
            aspirin-triggered resolvin D2 0
            aspirin-triggered resolvin D3 0
            aspirin-triggered resolvin D4 0
            aspirin-triggered resolvin D5 0
            aspirin-triggered resolvin D6 0
            resolvin D1 20
            resolvin D2 14
            resolvin D3 0
            resolvin D4 0
            resolvin D5 0
            resolvin D6 0
            resolvin E1 0
            resolvin E2 0
            resolvin E3 0
            resolvin T1 0
            resolvin T2 0
            resolvin T3 0
            resolvin T4 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic group 18737
                              organic divalent group 18728
                                organodiyl group 18728
                                  carbonyl group 18675
                                    carbonyl compound 18675
                                      carboxylic acid 18373
                                        monocarboxylic acid 17636
                                          fatty acid 16008
                                            long-chain fatty acid 1791
                                              resolvin 20
                                                (18R)-resolvin E3 0
                                                (18S)-resolvin E1 0
                                                (18S)-resolvin E2 0
                                                (6Z,8E,10E,14Z,16E,18R)-5,12,18-trihydroxyicosapentaenoic acid 0
                                                16-oxoresolvin D2 0
                                                17-oxoresolvin D1 0
                                                7-oxoresolvin D2 0
                                                8-oxoresolvin D1 0
                                                aspirin-triggered resolvin D1 0
                                                aspirin-triggered resolvin D2 0
                                                aspirin-triggered resolvin D3 0
                                                aspirin-triggered resolvin D4 0
                                                aspirin-triggered resolvin D5 0
                                                aspirin-triggered resolvin D6 0
                                                resolvin D1 20
                                                resolvin D2 14
                                                resolvin D3 0
                                                resolvin D4 0
                                                resolvin D5 0
                                                resolvin D6 0
                                                resolvin E1 0
                                                resolvin E2 0
                                                resolvin E3 0
                                                resolvin T1 0
                                                resolvin T2 0
                                                resolvin T3 0
                                                resolvin T4 0
paths to the root