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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:132050 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-norverapamil. The major active metabolite of verapamil.
Synonyms:exact_synonym: rac-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-(propan-2-yl)pentanenitrile
 related_synonym: (RS)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-2-(propan-2-yl)pentanenitrile;   (RS)-norverapamil;   5-((3,4-Dimethoxyphenethyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile;   Formula=C26H36N2O4;   alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)amino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile;   desmethylverapamil;   rac-norverapamil
 xref: CAS:67018-85-3;   Chemspider:94724;   HMDB:HMDB0060540
 xref_mesh: MESH:C016904
 xref: PMID:10336579;   PMID:10613599;   PMID:10701911;   PMID:11377051;   PMID:11456122;   PMID:11777750;   PMID:11996822;   PMID:12016885;   PMID:15563760;   PMID:15918524;   PMID:16013069;   PMID:16892180;   PMID:17981422;   PMID:18193210;   PMID:18806964;   PMID:19746412;   PMID:19898809;   PMID:20166433;   PMID:20604832;   PMID:21135265;   PMID:22300394;   PMID:22677487;   PMID:23757929;   PMID:23916407;   PMID:24044638;   PMID:24532601;   PMID:25237334;   PMID:25571292;   PMID:25650380;   PMID:26265240;   PMID:26643325;   PMID:27457673;   PMID:27750166;   PMID:8554934;   PMID:9572542;   PMID:9613945;   Reaxys:5458977;   Wikipedia:Norverapamil

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norverapamil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases activity ISO norverapamil results in decreased activity of CYP3A5 protein CTD PMID:15689501 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19718
      biological role 19717
        xenobiotic 18379
          norverapamil 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    main group molecular entity 19655
                      s-block molecular entity 19397
                        hydrogen molecular entity 19387
                          hydrides 18419
                            inorganic hydride 17380
                              pnictogen hydride 17349
                                nitrogen hydride 17216
                                  azane 16932
                                    ammonia 16931
                                      organic amino compound 16930
                                        secondary amino compound 6511
                                          2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl]amino\}-2-(propan-2-yl)pentanenitrile 1
                                            (R)-norverapamil 1
                                              norverapamil 1
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