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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fluoroindole
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Accession:CHEBI:131960 term browser browse the term
Definition:An organofluorine compound that is a compound based on an indole skeleton, containing one or more fluorine atoms.
Synonyms:related_synonym: fluoroindoles


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680C91 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO TDO inhibitor LM10 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CYP1A1 mRNA] CTD PMID:24930766 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G H2ax H2A.X variant histone decreases expression ISO TDO inhibitor LM10 results in decreased expression of H2AX protein modified form CTD PMID:26651356 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Polk DNA polymerase kappa decreases expression ISO TDO inhibitor LM10 results in decreased expression of POLK protein CTD PMID:26651356 NCBI chr 2:27,305,718...27,364,906
Ensembl chr 2:27,305,728...27,364,906
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases activity ISO TDO inhibitor LM10 results in decreased activity of TDO2 protein CTD PMID:21726069 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      molecular entity 19772
        polyatomic entity 19691
          heteroatomic molecular entity 19621
            halide 18072
              organohalogen compound 17837
                organofluorine compound 10899
                  fluoroindole 4
                    5-fluoroindole 0
                    680C91 4
                    brivanib + 0
                    brivanib alaninate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19772
      composite particle 19772
        hadron 19772
          baryon 19772
            nucleon 19772
              atomic nucleus 19772
                atom 19772
                  main group element atom 19662
                    p-block element atom 19662
                      carbon group element atom 19579
                        carbon atom 19569
                          organic molecular entity 19569
                            organic molecule 19502
                              organic cyclic compound 19329
                                organic heterocyclic compound 18544
                                  organic heteropolycyclic compound 18035
                                    organic heterobicyclic compound 16783
                                      benzopyrrole 9559
                                        indoles 9229
                                          haloindole 4
                                            fluoroindole 4
                                              5-fluoroindole 0
                                              680C91 4
                                              brivanib + 0
                                              brivanib alaninate 0
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