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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:fluoroindole
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Accession:CHEBI:131960 term browser browse the term
Definition:An organofluorine compound that is a compound based on an indole skeleton, containing one or more fluorine atoms.
Synonyms:related_synonym: fluoroindoles


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680C91 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO TDO inhibitor LM10 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CYP1A1 mRNA] CTD PMID:24930766 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G H2ax H2A.X variant histone decreases expression ISO TDO inhibitor LM10 results in decreased expression of H2AX protein modified form CTD PMID:26651356 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Polk DNA polymerase kappa decreases expression ISO TDO inhibitor LM10 results in decreased expression of POLK protein CTD PMID:26651356 NCBI chr 2:27,822,228...27,882,331
Ensembl chr 2:27,822,679...27,882,313 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase decreases activity ISO TDO inhibitor LM10 results in decreased activity of TDO2 protein CTD PMID:21726069 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    chemical entity 19919
      molecular entity 19919
        polyatomic entity 19876
          heteroatomic molecular entity 19834
            halide 18704
              organohalogen compound 18568
                organofluorine compound 14999
                  fluoroindole 4
                    5-fluoroindole 0
                    680C91 4
                    L-803087 0
                    LY-367,265 0
                    TA-1887 0
                    brivanib + 0
                    brivanib alaninate 0
                    indolauxipyr + 0
                    indolauxipyr-cyanomethyl 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    p-block element atom 19865
                      carbon group element atom 19804
                        carbon atom 19801
                          organic molecular entity 19801
                            organic molecule 19754
                              organic cyclic compound 19544
                                organic heterocyclic compound 18909
                                  organic heteropolycyclic compound 18316
                                    organic heterobicyclic compound 17252
                                      benzopyrrole 9733
                                        indoles 9420
                                          haloindole 4
                                            fluoroindole 4
                                              5-fluoroindole 0
                                              680C91 4
                                              L-803087 0
                                              LY-367,265 0
                                              TA-1887 0
                                              brivanib + 0
                                              brivanib alaninate 0
                                              indolauxipyr + 0
                                              indolauxipyr-cyanomethyl 0
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