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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,3-bis(p-hydroxyphenyl)pentane-1,4-diene
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Accession:CHEBI:131953 term browser browse the term
Definition:A norlignan that is pentane-1,4-diene in which a hydrogen at position 1 and a hydrogen at position 3 are replaced by p-hydroxyphenyl groups. The isomer in which the 1,2-disubstituted double bond has Z configuration is known as nyasol; the corresponding E isomer is hinokiresinol.
Synonyms:exact_synonym: 4-[1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol
 related_synonym: Formula=C17H16O2;   InChI=1S/C17H16O2/c1-2-14(15-7-11-17(19)12-8-15)6-3-13-4-9-16(18)10-5-13/h2-12,14,18-19H,1H2;   InChIKey=VEAUNWQYYMXIRB-UHFFFAOYSA-N;   SMILES=C=1C(=CC=C(C1)O)C(C=C)C=CC2=CC=C(C=C2)O
 xref: PMID:16309307


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(-)-hinokiresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:30322157 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO hinokiresinol inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:30322157 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:30322157 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:30322157 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      atom 19819
        nonmetal atom 19707
          carbon atom 19630
            organic molecular entity 19630
              olefinic compound 15494
                1,3-bis(p-hydroxyphenyl)pentane-1,4-diene 4
                  (+)-nyasol 0
                  (-)-hinokiresinol 4
                  (-)-nyasol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      carbon group element atom 19640
                        carbon atom 19630
                          organic molecular entity 19630
                            organic molecule 19569
                              organic cyclic compound 19360
                                organic aromatic compound 19184
                                  phenols 18147
                                    polyphenol 6718
                                      1,3-bis(p-hydroxyphenyl)pentane-1,4-diene 4
                                        (+)-nyasol 0
                                        (-)-hinokiresinol 4
                                        (-)-nyasol 0
paths to the root