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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,3-bis(p-hydroxyphenyl)pentane-1,4-diene
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Accession:CHEBI:131953 term browser browse the term
Definition:A norlignan that is pentane-1,4-diene in which a hydrogen at position 1 and a hydrogen at position 3 are replaced by p-hydroxyphenyl groups. The isomer in which the 1,2-disubstituted double bond has Z configuration is known as nyasol; the corresponding E isomer is hinokiresinol.
Synonyms:exact_synonym: 4-[1-(4-hydroxyphenyl)penta-1,4-dien-3-yl]phenol
 related_synonym: Formula=C17H16O2;   InChI=1S/C17H16O2/c1-2-14(15-7-11-17(19)12-8-15)6-3-13-4-9-16(18)10-5-13/h2-12,14,18-19H,1H2;   InChIKey=VEAUNWQYYMXIRB-UHFFFAOYSA-N;   SMILES=C=1C(=CC=C(C1)O)C(C=C)C=CC2=CC=C(C=C2)O
 xref: PMID:16309307


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(-)-hinokiresinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 multiple interactions ISO hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:30322157 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO hinokiresinol inhibits the reaction [[Lipopolysaccharides results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:30322157 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] CTD PMID:30322157 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; hinokiresinol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:30322157 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    chemical entity 19785
      atom 19782
        nonmetal atom 19657
          carbon atom 19561
            organic molecular entity 19561
              olefinic compound 14455
                1,3-bis(p-hydroxyphenyl)pentane-1,4-diene 4
                  (+)-nyasol 0
                  (-)-hinokiresinol 4
                  (-)-nyasol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic aromatic compound 19116
                                  phenols 18109
                                    polyphenol 6656
                                      1,3-bis(p-hydroxyphenyl)pentane-1,4-diene 4
                                        (+)-nyasol 0
                                        (-)-hinokiresinol 4
                                        (-)-nyasol 0
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