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ONTOLOGY REPORT - ANNOTATIONS


Term:violacein
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Accession:CHEBI:131914 term browser browse the term
Definition:A member of the class of hydroxyindoles resulting from the formal oxidative coupling between the 3-position of 1,3-dihydro-2H-indol-2-one and the 3-position of 1,3-dihydro-2H-pyrrol-2-one, which is substituted at the 5 position by a 5-hydroxy-1H-indol-3-yl group, where the newly-formed double bond has E configuration. It is a purple chromobacterial pigment that has antibacterial, antifungal, antiprotozoan, and anticancer properties.
Synonyms:exact_synonym: (3E)-3-[5-(5-hydroxy-1H-indol-3-yl)-2-oxo-1,2-dihydro-3H-pyrrol-3-ylidene]-1,3-dihydro-2H-indol-2-one
 related_synonym: Formula=C20H13N3O3;   InChI=1S/C20H13N3O3/c24-10-5-6-15-12(7-10)14(9-21-15)17-8-13(19(25)23-17)18-11-3-1-2-4-16(11)22-20(18)26/h1-9,21,24H,(H,22,26)(H,23,25)/b18-13+;   InChIKey=XAPNKXIRQFHCHN-QGOAFFKASA-N;   SMILES=O=C/1NC=2C(\\C1=C/3\\C=C(NC3=O)C=4C=5C(NC4)=CC=C(O)C5)=CC=CC2
 xref: CAS:548-54-9 "ChemIDplus";   KEGG:C21136
 xref_mesh: MESH:C063155
 xref: MetaCyc:VIOLACEIN;   PMID:21779844 "SUBMITTER";   PMID:25592762 "Europe PMC";   PMID:25652759 "Europe PMC";   PMID:26339614 "Europe PMC";   PMID:26428920 "Europe PMC";   PMID:26521020 "Europe PMC";   PMID:26916415 "Europe PMC";   Reaxys:49923 "Reaxys"


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violacein term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        antimicrobial agent 17151
          antibacterial agent 12904
            violacein 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                lactam 2855
                                                  gamma-lactam 346
                                                    oxindoles 158
                                                      violacein 3
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