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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:8-epi-prostaglandin E2
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Accession:CHEBI:131888 term browser browse the term
Definition:A prostanoid that is prostaglandin E2 having inverted stereochemistry at the 8-position.
Synonyms:exact_synonym: (5Z,8beta,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
 related_synonym: 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid;   8-epi-PGE2;   8-iso-PGE2;   8-isoprostaglandin E2;   Formula=C20H32O5;   InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17+,19+/m0/s1;   InChIKey=XEYBRNLFEZDVAW-CLQOMRTCSA-N;   SMILES=C(\\[C@H]1[C@@H](CC([C@H]1C/C=C\\CCCC(O)=O)=O)O)=C/[C@H](CCCCC)O
 xref: CAS:27415-25-4;   Chemspider:4446334;   HMDB:HMDB0005844;   LIPID_MAPS_instance:LMFA03110003
 xref_mesh: MESH:C011987
 xref: PMID:10636418;   PMID:10718110;   PMID:11160628;   PMID:12376370;   PMID:12626646;   PMID:12716476;   PMID:12869634;   PMID:15257985;   PMID:17690331;   PMID:19088946;   PMID:19513831;   PMID:20036885;   PMID:22015024;   PMID:22565502;   PMID:22959706;   PMID:26209241;   PMID:9013211;   PMID:9099206;   PMID:9316826;   Reaxys:4709355

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8-epi-prostaglandin E2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger4 prostaglandin E receptor 4 affects response to substance ISO PTGER4 protein affects the susceptibility to 8-isoprostaglandin E2 CTD PMID:22565502 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        pharmaceutical 19275
          drug 19275
            bronchoconstrictor agent 65
              8-epi-prostaglandin E2 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        monocarboxylic acid 17407
                                          fatty acid 15845
                                            fatty acid derivative 1021
                                              icosanoid 453
                                                prostanoid 395
                                                  prostaglandin 390
                                                    prostaglandins E 233
                                                      prostaglandin E2 230
                                                        8-epi-prostaglandin E2 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.