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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:8-epi-prostaglandin E2
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Accession:CHEBI:131888 term browser browse the term
Definition:A prostanoid that is prostaglandin E2 having inverted stereochemistry at the 8-position.
Synonyms:exact_synonym: (5Z,8beta,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
 related_synonym: 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid;   8-epi-PGE2;   8-iso-PGE2;   8-isoprostaglandin E2;   Formula=C20H32O5;   InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17+,19+/m0/s1;   InChIKey=XEYBRNLFEZDVAW-CLQOMRTCSA-N;   SMILES=C(\\[C@H]1[C@@H](CC([C@H]1C/C=C\\CCCC(O)=O)=O)O)=C/[C@H](CCCCC)O
 xref: CAS:27415-25-4;   Chemspider:4446334;   HMDB:HMDB0005844;   LIPID_MAPS_instance:LMFA03110003
 xref_mesh: MESH:C011987
 xref: PMID:10636418;   PMID:10718110;   PMID:11160628;   PMID:12376370;   PMID:12626646;   PMID:12716476;   PMID:12869634;   PMID:15257985;   PMID:17690331;   PMID:19088946;   PMID:19513831;   PMID:20036885;   PMID:22015024;   PMID:22565502;   PMID:22959706;   PMID:26209241;   PMID:9013211;   PMID:9099206;   PMID:9316826;   Reaxys:4709355

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8-epi-prostaglandin E2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger4 prostaglandin E receptor 4 affects response to substance ISO PTGER4 protein affects the susceptibility to 8-isoprostaglandin E2 CTD PMID:22565502 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
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  CHEBI ontology 19812
    role 19761
      application 19471
        pharmaceutical 19319
          drug 19319
            bronchoconstrictor agent 65
              8-epi-prostaglandin E2 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        monocarboxylic acid 17632
                                          fatty acid 16012
                                            fatty acid derivative 1047
                                              icosanoid 460
                                                prostanoid 399
                                                  prostaglandin 394
                                                    prostaglandins E 234
                                                      prostaglandin E2 231
                                                        8-epi-prostaglandin E2 1
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