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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:8-epi-prostaglandin E2
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Accession:CHEBI:131888 term browser browse the term
Definition:A prostanoid that is prostaglandin E2 having inverted stereochemistry at the 8-position.
Synonyms:exact_synonym: (5Z,8beta,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid
 related_synonym: 7-[3-Hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]-5-heptenoic acid;   8-epi-PGE2;   8-iso-PGE2;   8-isoprostaglandin E2;   Formula=C20H32O5;   InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17+,19+/m0/s1;   InChIKey=XEYBRNLFEZDVAW-CLQOMRTCSA-N;   SMILES=C(\\[C@H]1[C@@H](CC([C@H]1C/C=C\\CCCC(O)=O)=O)O)=C/[C@H](CCCCC)O
 xref: CAS:27415-25-4;   Chemspider:4446334;   HMDB:HMDB0005844;   LIPID_MAPS_instance:LMFA03110003
 xref_mesh: MESH:C011987
 xref: PMID:10636418;   PMID:10718110;   PMID:11160628;   PMID:12376370;   PMID:12626646;   PMID:12716476;   PMID:12869634;   PMID:15257985;   PMID:17690331;   PMID:19088946;   PMID:19513831;   PMID:20036885;   PMID:22015024;   PMID:22565502;   PMID:22959706;   PMID:26209241;   PMID:9013211;   PMID:9099206;   PMID:9316826;   Reaxys:4709355

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8-epi-prostaglandin E2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger4 prostaglandin E receptor 4 affects response to substance ISO PTGER4 protein affects the susceptibility to 8-isoprostaglandin E2 CTD PMID:22565502 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      application 19781
        pharmaceutical 19624
          drug 19655
            bronchoconstrictor agent 67
              8-epi-prostaglandin E2 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  carbonyl group 18903
                                    carbonyl compound 18925
                                      carboxylic acid 18597
                                        monocarboxylic acid 17843
                                          fatty acid 16480
                                            fatty acid derivative 8762
                                              icosanoid 465
                                                prostanoid 402
                                                  prostaglandin 397
                                                    prostaglandins E 233
                                                      prostaglandin E2 230
                                                        8-epi-prostaglandin E2 1
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