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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:8,5'-cyclo-2'-deoxyadenosine
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Accession:CHEBI:131825 term browser browse the term
Definition:An organic heterotetracyclic compound obtained by intramolecular formation of a C-C bond between positions 8 and 5' of 2'-deoxyadenosine.
Synonyms:exact_synonym: (6R,7S,8S,10R)-4-amino-7,8,9,10-tetrahydro-6H-7,10-epoxyazepino[1,2-e]purine-6,8-diol
 related_synonym: 2'-Deoxy-8,5'-cycloadenosine;   8,5'-Cda;   Formula=C10H11N5O3;   InChI=1S/C10H11N5O3/c11-8-5-9(13-2-12-8)15-4-1-3(16)7(18-4)6(17)10(15)14-5/h2-4,6-7,16-17H,1H2,(H2,11,12,13)/t3-,4+,6-,7-/m0/s1;   InChIKey=MBVGIEDXZGVICG-FXZMZVCPSA-N;   SMILES=[C@H]12N3C=4N=CN=C(C4N=C3[C@H]([C@]([C@H](C1)O)(O2)[H])O)N;   cyclo-dA;   cyclodA
 xref: CAS:117182-88-4
 xref_mesh: MESH:C056752
 xref: PMID:22817898;   PMID:23961697;   PMID:24471831;   PMID:25034731;   PMID:25605892;   PMID:26344223;   Reaxys:8118367


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8,5'-cyclo-2'-deoxyadenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neil1 nei-like DNA glycosylase 1 affects metabolic processing ISO NEIL1 protein affects the metabolism of 8,5'-cyclo-2'-deoxyadenosine CTD PMID:20067321 NCBI chr 8:57,550,142...57,556,884
Ensembl chr 8:57,550,147...57,556,258 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      application 19630
        NMR chemical shift reference compound 17936
          ammonia 17795
            organic amino compound 17795
              aromatic amine 15398
                8,5'-cyclo-2'-deoxyadenosine 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19811
    subatomic particle 19809
      composite particle 19809
        hadron 19840
          baryon 19809
            nucleon 19809
              atomic nucleus 19809
                atom 19809
                  main group element atom 19759
                    p-block element atom 19759
                      carbon group element atom 19708
                        carbon atom 19734
                          organic molecular entity 19705
                            heteroorganic entity 19459
                              organochalcogen compound 19222
                                organooxygen compound 19137
                                  carbohydrates and carbohydrate derivatives 15269
                                    carbohydrate 15284
                                      carbohydrate derivative 14290
                                        glycosyl compound 13035
                                          N-glycosyl compound 5808
                                            nucleoside 5662
                                              deoxyribonucleoside 2870
                                                2'-deoxyribonucleoside 2248
                                                  purine 2'-deoxyribonucleoside 34
                                                    purines 2'-deoxy-D-ribonucleoside 14
                                                      2'-deoxyadenosine 8
                                                        8,5'-cyclo-2'-deoxyadenosine 1
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