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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
multiple interactions |
ISO |
[bisphenol A co-treated with Stigmasterol] results in increased expression of ABCB11 mRNA; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of ABCB11 mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcg5 |
ATP binding cassette subfamily G member 5 |
multiple interactions decreases expression |
ISO |
[Stigmasterol co-treated with KNG1 protein modified form] results in decreased expression of ABCG5 mRNA; [Stigmasterol co-treated with Oligomycins] results in decreased expression of ABCG5 mRNA; [Stigmasterol co-treated with Rotenone] results in decreased expression of ABCG5 mRNA Stigmasterol results in decreased expression of ABCG5 mRNA |
CTD |
PMID:23454145 |
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NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
multiple interactions decreases expression |
ISO |
[Stigmasterol co-treated with Oligomycins] results in decreased expression of ABCG8 mRNA; [Stigmasterol co-treated with Rotenone] results in decreased expression of ABCG8 mRNA Stigmasterol results in decreased expression of ABCG8 mRNA |
CTD |
PMID:23454145 |
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NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
multiple interactions |
ISO |
[Stigmasterol co-treated with KNG1 protein modified form] results in decreased expression of ACAT1 mRNA; [Stigmasterol co-treated with Oligomycins] results in decreased expression of ACAT1 mRNA; [Stigmasterol co-treated with Rotenone] results in decreased expression of ACAT1 mRNA |
CTD |
PMID:23454145 |
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NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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G |
Ankrd1 |
ankyrin repeat domain 1 |
multiple interactions |
ISO |
[NR1H4 gene mutant form affects the susceptibility to Stigmasterol] which results in decreased expression of ANKRD1 mRNA |
CTD |
PMID:30245210 |
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NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
[bisphenol A co-treated with Stigmasterol] results in increased expression of APOA1 mRNA; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of APOA1 mRNA]; Stigmasterol promotes the reaction [GW 4064 results in increased expression of APOA1 mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Brinp3 |
BMP/retinoic acid inducible neural specific 3 |
multiple interactions |
ISO |
[NR1H4 gene mutant form affects the susceptibility to Stigmasterol] which results in decreased expression of BRINP3 mRNA |
CTD |
PMID:30245210 |
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NCBI chr13:58,413,883...58,846,828
Ensembl chr13:58,413,883...58,846,770
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G |
Cldn11 |
claudin 11 |
multiple interactions |
ISO |
[bisphenol A co-treated with Stigmasterol] results in increased expression of CLDN11 mRNA; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of CLDN11 mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
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G |
Dnmt3l |
DNA methyltransferase 3 like |
multiple interactions |
ISO |
[bisphenol A co-treated with Stigmasterol] results in increased expression of DNMT3L mRNA; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of DNMT3L mRNA] |
CTD |
PMID:30245210 |
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NCBI chr20:10,614,933...10,629,516
Ensembl chr20:10,614,934...10,629,516
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with Stigmasterol] results in increased expression of ESR1 mRNA; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of ESR1 mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Fshr |
follicle stimulating hormone receptor |
multiple interactions |
ISO |
Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of FSHR mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G |
Gabarap |
GABA type A receptor-associated protein |
decreases expression |
ISO |
Stigmasterol results in decreased expression of GABARAP mRNA |
CTD |
PMID:30245210 |
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NCBI chr10:54,714,834...54,717,769
Ensembl chr10:54,714,198...54,717,765
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G |
Gfra1 |
GDNF family receptor alpha 1 |
multiple interactions |
ISO |
[bisphenol A co-treated with Stigmasterol] results in decreased expression of GFRA1 mRNA; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in decreased expression of GFRA1 mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of GFRA1 mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions increases expression |
ISO |
[Stigmasterol co-treated with KNG1 protein modified form] results in increased expression of HMGCR mRNA; [Stigmasterol co-treated with Oligomycins] results in decreased expression of HMGCR mRNA; [Stigmasterol co-treated with Rotenone] results in decreased expression of HMGCR mRNA Stigmasterol results in increased expression of HMGCR mRNA |
CTD |
PMID:23454145 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hoxa5 |
homeo box A5 |
multiple interactions |
ISO |
[NR1H4 gene mutant form affects the susceptibility to Stigmasterol] which results in decreased expression of HOXA5 mRNA |
CTD |
PMID:30245210 |
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NCBI chr 4:81,302,341...81,306,234
Ensembl chr 4:81,302,353...81,306,234
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G |
Ifi35 |
interferon-induced protein 35 |
decreases expression |
ISO |
Stigmasterol results in decreased expression of IFI35 mRNA |
CTD |
PMID:30245210 |
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NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952
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G |
Il10 |
interleukin 10 |
increases secretion |
ISO |
Stigmasterol results in increased secretion of IL10 protein |
CTD |
PMID:23454145 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
Stigmasterol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] |
CTD |
PMID:23535395 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Kng2 |
kininogen 2 |
multiple interactions |
ISO |
[Stigmasterol co-treated with KNG1 protein modified form] results in decreased expression of ABCG5 mRNA; [Stigmasterol co-treated with KNG1 protein modified form] results in decreased expression of ACAT1 mRNA; [Stigmasterol co-treated with KNG1 protein modified form] results in increased expression of HMGCR mRNA; [Stigmasterol co-treated with KNG1 protein modified form] results in increased expression of NPC1L1 mRNA |
CTD |
PMID:23454145 |
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NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
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G |
Mybpc2 |
myosin binding protein C2 |
multiple interactions |
ISO |
[NR1H4 gene mutant form affects the susceptibility to Stigmasterol] which results in decreased expression of MYBPC2 mRNA |
CTD |
PMID:30245210 |
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NCBI chr 1:94,994,104...95,017,650
Ensembl chr 1:94,994,104...95,017,584
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G |
Nanog |
Nanog homeobox |
decreases expression multiple interactions |
ISO |
Stigmasterol results in decreased expression of NANOG mRNA [bisphenol A co-treated with Stigmasterol] results in decreased expression of NANOG mRNA; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of NANOG mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
Stigmasterol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Stigmasterol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:23535395 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Npc1l1 |
NPC1 like intracellular cholesterol transporter 1 |
multiple interactions |
ISO |
[Stigmasterol co-treated with KNG1 protein modified form] results in increased expression of NPC1L1 mRNA; [Stigmasterol co-treated with Rotenone] results in increased expression of NPC1L1 mRNA |
CTD |
PMID:23454145 |
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NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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G |
Nr0b1 |
nuclear receptor subfamily 0, group B, member 1 |
multiple interactions decreases expression |
ISO |
[bisphenol A co-treated with Stigmasterol] results in increased expression of NR0B1 mRNA; GW 4064 promotes the reaction [Stigmasterol results in increased expression of NR0B1 mRNA]; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of NR0B1 mRNA]; NR1H4 gene mutant form inhibits the reaction [Stigmasterol results in decreased expression of NR0B1 mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of NR0B1 mRNA] |
CTD |
PMID:30245210 |
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NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
multiple interactions |
ISO |
Stigmasterol promotes the reaction [GW 4064 results in increased expression of NR0B2 mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions decreases expression affects response to substance |
ISO |
[bisphenol A co-treated with Stigmasterol] results in decreased expression of NR1H4 mRNA; [NR1H4 gene mutant form affects the susceptibility to Stigmasterol] which results in decreased expression of ANKRD1 mRNA; [NR1H4 gene mutant form affects the susceptibility to Stigmasterol] which results in decreased expression of BRINP3 mRNA; [NR1H4 gene mutant form affects the susceptibility to Stigmasterol] which results in decreased expression of HOXA5 mRNA; [NR1H4 gene mutant form affects the susceptibility to Stigmasterol] which results in decreased expression of MYBPC2 mRNA; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in decreased expression of GFRA1 mRNA]; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in decreased expression of ZBTB16 mRNA]; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of ABCB11 mRNA]; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of APOA1 mRNA]; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of CLDN11 mRNA]; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of DNMT3L mRNA]; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of ESR1 mRNA]; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in increased expression of NR0B1 mRNA]; NR1H4 gene mutant form inhibits the reaction [Stigmasterol results in decreased expression of NR0B1 mRNA]; NR1H4 gene mutant form inhibits the reaction [Stigmasterol results in decreased expression of ZBTB16 mRNA] Stigmasterol results in decreased expression of NR1H4 mRNA |
CTD |
PMID:30245210 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
Stigmasterol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Stigmasterol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] |
CTD |
PMID:23535395 |
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Rpl18a |
ribosomal protein L18A |
decreases expression |
ISO |
Stigmasterol results in decreased expression of RPL18A mRNA |
CTD |
PMID:30245210 |
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NCBI chr16:18,542,572...18,544,578
Ensembl chr16:18,542,566...18,545,546
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G |
Rpl31 |
ribosomal protein L31 |
decreases expression |
ISO |
Stigmasterol results in decreased expression of RPL31 mRNA |
CTD |
PMID:30245210 |
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NCBI chr 9:41,647,401...41,650,886
Ensembl chr 9:41,647,426...41,662,129
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G |
Rpl36 |
ribosomal protein L36 |
decreases expression |
ISO |
Stigmasterol results in decreased expression of RPL36 mRNA |
CTD |
PMID:30245210 |
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NCBI chr 9:1,441,986...1,447,397
Ensembl chr 6:98,809,534...98,809,897
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G |
Rpph1 |
ribonuclease P RNA component H1 |
decreases expression |
ISO |
Stigmasterol results in decreased expression of RPPH1 mRNA |
CTD |
PMID:30245210 |
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NCBI chr15:24,033,679...24,033,935
Ensembl chr15:24,033,662...24,033,959
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G |
Rps14 |
ribosomal protein S14 |
decreases expression |
ISO |
Stigmasterol results in decreased expression of RPS14 mRNA |
CTD |
PMID:30245210 |
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NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166
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G |
Rps27 |
ribosomal protein S27 |
decreases expression |
ISO |
Stigmasterol results in decreased expression of RPS27 mRNA |
CTD |
PMID:30245210 |
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NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964
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G |
Rps7 |
ribosomal protein S7 |
decreases expression |
ISO |
Stigmasterol results in decreased expression of RPS7 mRNA |
CTD |
PMID:30245210 |
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NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
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G |
Stra8 |
stimulated by retinoic acid 8 |
decreases expression multiple interactions |
ISO |
Stigmasterol results in decreased expression of STRA8 mRNA GW 4064 inhibits the reaction [Stigmasterol results in decreased expression of STRA8 mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of STRA8 mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 4:63,601,443...63,624,777
Ensembl chr 4:63,601,604...63,624,771
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G |
Tm2d3 |
TM2 domain containing 3 |
decreases expression |
ISO |
Stigmasterol results in decreased expression of TM2D3 mRNA |
CTD |
PMID:30245210 |
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NCBI chr 1:119,264,576...119,277,099
Ensembl chr 1:119,264,576...119,277,099
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G |
Tnf |
tumor necrosis factor |
increases secretion multiple interactions |
ISO |
Stigmasterol results in increased secretion of TNF protein Stigmasterol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
CTD |
PMID:23454145 PMID:23535395 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Zbtb16 |
zinc finger and BTB domain containing 16 |
multiple interactions decreases expression |
ISO |
[bisphenol A co-treated with Stigmasterol] results in decreased expression of ZBTB16 mRNA; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in decreased expression of ZBTB16 mRNA]; NR1H4 gene mutant form inhibits the reaction [Stigmasterol results in decreased expression of ZBTB16 mRNA]; Stigmasterol inhibits the reaction [GW 4064 results in decreased expression of ZBTB16 mRNA] |
CTD |
PMID:30245210 |
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NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
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