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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor
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Accession:CHEBI:131699 term browser browse the term
Definition:A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7).
Synonyms:related_synonym: DNA duplicase inhibitor;   DNA duplicase inhibitors;   DNA nucleotidyltransferase (DNA-directed) inhibitor;   DNA nucleotidyltransferase (DNA-directed) inhibitors;   DNA nucleotidyltransferase inhibitor;   DNA nucleotidyltransferase inhibitors;   DNA polymerase I inhibitor;   DNA polymerase I inhibitors;   DNA polymerase II inhibitor;   DNA polymerase II inhibitors;   DNA polymerase III inhibitor;   DNA polymerase III inhibitors;   DNA polymerase alpha inhibitor;   DNA polymerase alpha inhibitors;   DNA polymerase beta inhibitor;   DNA polymerase beta inhibitors;   DNA polymerase gamma inhibitor;   DNA polymerase gamma inhibitors;   DNA polymerase inhibitor;   DNA polymerase inhibitors;   DNA replicase inhibitor;   DNA replicase inhibitors;   DNA-dependent DNA polymerase inhibitor;   DNA-dependent DNA polymerase inhibitors;   DNA-directed DNA polymerase (EC 2.7.7.7) inhibitors;   EC 2.7.7.7 inhibitor;   EC 2.7.7.7 inhibitors;   Klenow fragment inhibitor;   Klenow fragment inhibitors;   Taq DNA polymerase inhibitor;   Taq DNA polymerase inhibitors;   Taq Pol I inhibitor;   Taq Pol I inhibitors;   Tca DNA polymerase inhibitor;   Tca DNA polymerase inhibitors;   deoxynucleate polymerase inhibitor;   deoxynucleate polymerase inhibitors;   deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitor;   deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) inhibitors;   deoxyribonucleate nucleotidyltransferase inhibitor;   deoxyribonucleate nucleotidyltransferase inhibitors;   deoxyribonucleic acid duplicase inhibitor;   deoxyribonucleic acid duplicase inhibitors;   deoxyribonucleic acid polymerase inhibitor;   deoxyribonucleic acid polymerase inhibitors;   deoxyribonucleic duplicase inhibitor;   deoxyribonucleic duplicase inhibitors;   deoxyribonucleic polymerase I inhibitor;   deoxyribonucleic polymerase I inhibitors;   deoxyribonucleic polymerase inhibitor;   deoxyribonucleic polymerase inhibitors;   duplicase inhibitor;   duplicase inhibitors;   sequenase inhibitor;   sequenase inhibitors
 xref: Wikipedia:DNA_polymerase


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3',4',7-trihydroxyisoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases expression
multiple interactions
ISO 3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA
3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]
CTD PMID:22914566 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases expression
ISO 3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCC1 mRNA]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]; Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA] CTD PMID:22914566 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases expression
ISO 3',4',7-trihydroxyisoflavone inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA] CTD PMID:22914566 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO 3',4',7-trihydroxyisoflavone results in increased expression of BAX mRNA
3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of BAX mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of BAX mRNA]
CTD PMID:22914566 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
ISO 3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of CASP3 mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased activity of CASP3 protein]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of CASP3 mRNA] CTD PMID:22914566 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO 3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of CASP9 mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased activity of CASP9 protein]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of CASP9 mRNA] CTD PMID:22914566 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]; CAT protein inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA] CTD PMID:22914566 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO 3',4',7-trihydroxyisoflavone promotes the reaction [Epirubicin results in increased expression of TP53 mRNA]; Epirubicin promotes the reaction [3',4',7-trihydroxyisoflavone results in increased expression of TP53 mRNA] CTD PMID:22914566 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin multiple interactions EXP pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein] CTD PMID:11102496 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid results in decreased expression of FN1 mRNA CTD PMID:18210741 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Il6 interleukin 6 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Silicon Dioxide analog results in increased expression of IL6 protein] CTD PMID:24793913 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] CTD PMID:24912985 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions EXP pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of OXT protein] CTD PMID:11102496 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein] CTD PMID:21638035 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein] CTD PMID:22253048 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
aphidicolin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein]; [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased expression of BSCL2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of CHEK1 protein]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin multiple interactions
increases expression
ISO [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased expression of BSCL2 mRNA] CTD PMID:22003191 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G Ccna2 cyclin A2 increases expression ISO Aphidicolin results in increased expression of CCNA2 mRNA CTD PMID:14738865 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of CHEK1 protein] CTD PMID:22003191 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions ISO Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]]
[7-hydroxystaurosporine results in decreased activity of [CHEK1 protein co-treated with BSCL2 protein]] inhibits the reaction [Aphidicolin results in increased expression of CHEK2 mRNA]
CTD PMID:18158334 PMID:22003191 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Aphidicolin results in increased expression of CYP26A1 mRNA CTD PMID:29990529 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO Aphidicolin results in increased expression of FGF8 mRNA CTD PMID:29990529 NCBI chr 1:265,492,949...265,498,965
Ensembl chr 1:265,493,124...265,498,831
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Aphidicolin inhibits the reaction [Docetaxel results in increased expression of H2AX protein] CTD PMID:20878124 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hoxb9 homeo box B9 decreases expression ISO Aphidicolin results in decreased expression of HOXB9 mRNA CTD PMID:29990529 NCBI chr10:84,119,772...84,124,963
Ensembl chr10:84,119,884...84,123,390
JBrowse link
G Hoxc6 homeo box C6 decreases expression ISO Aphidicolin results in decreased expression of HOXC6 mRNA CTD PMID:29990529 NCBI chr 7:144,612,230...144,626,036
Ensembl chr 7:144,623,555...144,625,516
JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases activity ISO
EXP
Aphidicolin results in decreased activity of POLA1 protein CTD PMID:224865 NCBI chr  X:62,382,604...62,698,830
Ensembl chr  X:62,382,608...62,698,830
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions ISO Caffeine promotes the reaction [Aphidicolin promotes the reaction [PRKDC protein results in increased phosphorylation of and results in increased activity of CHEK2 protein]] CTD PMID:18158334 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Rxra retinoid X receptor alpha increases expression ISO Aphidicolin results in increased expression of RXRA mRNA CTD PMID:14738865 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Aphidicolin results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Tbx6 T-box transcription factor 6 decreases expression ISO Aphidicolin results in decreased expression of TBX6 mRNA CTD PMID:29990529 NCBI chr 1:198,214,797...198,218,706
Ensembl chr 1:198,214,797...198,218,706
JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 increases expression ISO Aphidicolin results in increased expression of TNFRSF8 protein CTD PMID:12441127 NCBI chr 5:163,186,349...163,231,578
Ensembl chr 5:163,186,349...163,231,578
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein]; [schizandrin B results in decreased activity of ATR protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRP53 protein] CTD PMID:22003191 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trim28 tripartite motif-containing 28 multiple interactions ISO [2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein] CTD PMID:22003191 NCBI chr 1:65,544,369...65,551,043
Ensembl chr 1:65,544,373...65,551,043
JBrowse link
G Wnt3a Wnt family member 3A decreases expression ISO Aphidicolin results in decreased expression of WNT3A mRNA CTD PMID:29990529 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
G Xrcc4 X-ray repair cross complementing 4 decreases response to substance ISO XRCC4 results in decreased susceptibility to Aphidicolin CTD PMID:21785230 NCBI chr 2:18,674,496...18,927,463
Ensembl chr 2:18,677,220...18,927,365
JBrowse link
corilagin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein] CTD PMID:30582900 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions EXP corilagin inhibits the reaction [1-naphthyl isothiocyanate decreases expression of nr1h4 mRNA and protein in rat liver]; corilagin increases expression of nr1h4 mRNA and protein in rat embryonic liver cells RGD PMID:29235094 RGD:15042872 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO corilagin results in decreased secretion of TNF protein CTD PMID:12628509 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
daidzein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ABCA1 mRNA CTD PMID:16963248 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO daidzein promotes the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:16156793 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO daidzein inhibits the reaction [ABCC4 protein results in increased export of Cyclic GMP]; daidzein promotes the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:16156793 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO daidzein inhibits the reaction [ABCC5 protein results in decreased susceptibility to Thioguanine]; daidzein inhibits the reaction [ABCC5 protein results in increased export of 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein] CTD PMID:16156793 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects transport ISO ABCG2 protein affects the transport of daidzein CTD PMID:18322075 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Add2 adducin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ADD2 mRNA CTD PMID:16963248 NCBI chr 4:117,691,294...117,887,556
Ensembl chr 4:117,743,710...117,882,464
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects binding
increases activity
ISO daidzein binds to and results in increased activity of AHR protein
daidzein binds to AHR protein
daidzein results in increased activity of AHR protein
CTD PMID:14644660 PMID:17869316 PMID:20436506 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Alpg alkaline phosphatase, germ cell increases expression ISO daidzein metabolite results in increased expression of ALPG mRNA CTD PMID:15993745 NCBI chr 9:94,164,667...94,184,972
Ensembl chr 9:94,178,221...94,181,010
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO [daidzein binds to ESR1 protein] which results in increased activity of ALPL protein; fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Ar androgen receptor multiple interactions
decreases expression
ISO
EXP
daidzein promotes the reaction [TGFB1I1 protein results in increased activity of AR protein]
daidzein inhibits the reaction [Flutamide results in decreased expression of AR mRNA]; daidzein inhibits the reaction [Flutamide results in decreased expression of AR protein]
daidzein results in decreased expression of AR mRNA
CTD PMID:10822019 PMID:17252558 PMID:23135684 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO daidzein results in decreased expression of ARHGDIA mRNA CTD PMID:15757668 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:100,067,341...100,099,517
Ensembl chr 4:100,067,341...100,099,517
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ATP6V0A2 mRNA CTD PMID:16963248 NCBI chr12:37,368,321...37,398,233
Ensembl chr12:37,363,906...37,425,596
JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain, 1A multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of BAZ1A mRNA CTD PMID:16963248 NCBI chr 6:75,793,223...75,873,854
Ensembl chr 6:75,793,960...75,874,235
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO daidzein results in decreased expression of BCL2 protein CTD PMID:12791511 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO daidzein results in decreased expression of BCL2L1 protein CTD PMID:12791511 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO [daidzein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA CTD PMID:19347870 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:61,912,210...61,940,697
Ensembl chr 4:61,912,210...61,940,696
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO daidzein results in increased expression of BRCA1 mRNA CTD PMID:17266178 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B affects expression ISO daidzein affects the expression of BUB1B mRNA CTD PMID:15721199 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G C3 complement C3 increases expression EXP daidzein results in increased expression of C3 mRNA CTD PMID:10822019 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:75,693,216...75,706,069
Ensembl chr 1:75,693,232...75,706,069
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
ISO
EXP
daidzein results in increased activity of CASP3 protein
daidzein results in increased expression of CASP3 protein
CTD PMID:12791511 PMID:29217487 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:47,853,699...47,891,147
Ensembl chr 5:47,853,818...47,891,668
JBrowse link
G Cat catalase multiple interactions ISO
EXP
[Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]
daidzein inhibits the reaction [Flutamide results in decreased activity of CAT protein]
CTD PMID:22981962 PMID:23135684 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO daidzein results in decreased expression of CCNA2 CTD PMID:21161820 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO daidzein results in increased expression of CCND1 mRNA CTD PMID:17266178 PMID:19800779 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:60,848,161...60,882,470
Ensembl chr11:60,848,131...60,882,379
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 protein] CTD PMID:21945492 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd80 Cd80 molecule multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of CD80 protein] CTD PMID:21945492 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of CD86 protein] CTD PMID:21945492 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions
decreases activity
ISO daidzein promotes the reaction [CDKN1A protein binds to CDK2 protein]
daidzein results in decreased activity of CDK2 protein
CTD PMID:11322924 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases activity ISO daidzein results in decreased activity of CDK4 protein CTD PMID:21161820 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO daidzein promotes the reaction [CDKN1A protein binds to CDK2 protein]; ESR2 affects the reaction [daidzein results in increased expression of CDKN1A] CTD PMID:11322924 PMID:21161820 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:38,708,915...38,781,598
Ensembl chr12:38,709,595...38,782,010
JBrowse link
G Chat choline O-acetyltransferase increases activity ISO daidzein results in increased activity of CHAT protein CTD PMID:16428827 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Ckb creatine kinase B increases activity
multiple interactions
ISO daidzein results in increased activity of CKB protein
Glucose inhibits the reaction [daidzein results in increased activity of CKB protein]
CTD PMID:16621514 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Clu clusterin decreases expression EXP daidzein results in decreased expression of CLU mRNA CTD PMID:10822019 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Comt catechol-O-methyltransferase decreases activity
multiple interactions
decreases expression
ISO daidzein results in decreased activity of COMT protein
daidzein inhibits the reaction [COMT protein results in increased methylation of 4-hydroxyestradiol]; fulvestrant inhibits the reaction [daidzein results in decreased expression of COMT mRNA]
CTD PMID:18192686 PMID:18497090 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cox7a2l cytochrome c oxidase subunit 7A2 like increases expression ISO daidzein results in increased expression of COX7A2L mRNA CTD PMID:17266178 NCBI chr 6:6,695,807...6,709,790
Ensembl chr 6:6,695,827...6,709,783
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO daidzein results in increased expression of CPT1A mRNA; daidzein results in increased expression of CPT1A protein CTD PMID:16362726 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP daidzein results in increased phosphorylation of and results in increased activity of CREB1 protein CTD PMID:16972265 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Genistein co-treated with daidzein] results in decreased expression of CRP protein CTD PMID:16332659 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 affects expression ISO daidzein affects the expression of CSNK2A2 mRNA CTD PMID:15721199 NCBI chr19:9,972,537...10,012,043
Ensembl chr19:9,972,537...10,012,043
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
multiple interactions
ISO daidzein results in increased expression of CXCL12 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of CXCL12 mRNA]
CTD PMID:23384675 PMID:28396216 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:57,718,496...57,745,749
Ensembl chr 3:57,718,364...57,746,097
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
multiple interactions
decreases expression
ISO daidzein results in decreased activity of CYP19A1 protein
[Genistein co-treated with biochanin A co-treated with daidzein] results in decreased activity of CYP19A1 protein; [Genistein co-treated with biochanin A co-treated with daidzein] results in decreased expression of CYP19A1 mRNA
daidzein results in decreased expression of CYP19A1 mRNA
CTD PMID:16023337 PMID:16965912 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions
decreases expression
ISO
EXP
daidzein results in decreased activity of CYP1A1 protein
daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 mRNA]; daidzein inhibits the reaction [Omeprazole results in increased expression of CYP1A1 protein]
daidzein results in decreased expression of CYP1A1 mRNA
daidzein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; fulvestrant inhibits the reaction [daidzein results in decreased expression of CYP1A1 mRNA]
CTD PMID:9395520 PMID:18420780 PMID:18451504 PMID:18497090 PMID:28985473 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO daidzein results in decreased activity of CYP1A2 protein CTD PMID:18420780 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects chemical synthesis
decreases activity
ISO CYP1B1 protein affects the chemical synthesis of daidzein
daidzein results in decreased activity of CYP1B1 protein
CTD PMID:15479032 PMID:18420780 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO daidzein results in decreased activity of CYP2C29 protein CTD PMID:18420780 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO daidzein results in decreased activity of CYP2D6 protein
daidzein results in decreased activity of CYP2D22 protein
CTD PMID:18420780 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions
ISO
EXP
daidzein results in decreased activity of CYP2E1 protein
daidzein inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]
CTD PMID:18420780 PMID:31870919 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression
decreases activity
EXP
ISO
daidzein results in increased expression of CYP3A4 mRNA
daidzein results in decreased activity of CYP3A4 protein
CTD PMID:18420780 PMID:31870919 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Dedd death effector domain-containing affects expression ISO daidzein affects the expression of DEDD mRNA CTD PMID:15721199 NCBI chr13:89,706,932...89,721,825
Ensembl chr13:89,718,066...89,721,454
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:209,097,894...209,116,978
Ensembl chr 2:209,097,927...209,116,965
JBrowse link
G Dio1 iodothyronine deiodinase 1 affects expression EXP daidzein affects the expression of DIO1 mRNA CTD PMID:24793811 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dock3 dedicator of cyto-kinesis 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of DOCK3 mRNA CTD PMID:16963248 NCBI chr 8:115,627,282...115,982,260
Ensembl chr 8:115,629,583...115,981,910
JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:10,846,493...10,882,560
Ensembl chr 9:10,846,596...10,882,649
JBrowse link
G Dusp4 dual specificity phosphatase 4 decreases expression ISO daidzein results in decreased expression of DUSP4 mRNA CTD PMID:16865672 NCBI chr16:61,080,767...61,090,973
Ensembl chr16:61,078,175...61,091,169
JBrowse link
G Ebag9 estrogen receptor binding site associated, antigen, 9 increases expression ISO daidzein results in increased expression of EBAG9 mRNA CTD PMID:17266178 NCBI chr 7:83,564,563...83,582,516
Ensembl chr 7:83,564,563...83,582,508
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:205,706,023...205,743,676
Ensembl chr 1:205,706,468...205,743,653
JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:94,362,249...94,408,884
Ensembl chr 9:94,362,299...94,408,885
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR protein; [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR protein CTD PMID:19347870 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions EXP daidzein results in increased phosphorylation of and results in increased activity of ELK1 protein CTD PMID:16972265 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Eno3 enolase 3 decreases expression ISO daidzein results in decreased expression of ENO3 mRNA CTD PMID:15757668 NCBI chr10:57,278,271...57,283,661
Ensembl chr10:57,278,307...57,283,653
JBrowse link
G Epha1 Eph receptor A1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of EPHA1 mRNA CTD PMID:16963248 NCBI chr 4:71,749,100...71,763,681
Ensembl chr 4:71,749,242...71,763,679
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease affects expression ISO daidzein affects the expression of ERCC5 mRNA CTD PMID:15721199 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Espn espin multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of ESPN mRNA CTD PMID:16963248 NCBI chr 5:169,293,356...169,331,338
Ensembl chr 5:169,293,904...169,331,163
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
affects response to substance
affects binding
decreases expression
ISO
EXP
[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein; [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR protein; [daidzein co-treated with ESR1 protein] results in increased expression of BGLAP mRNA; [daidzein co-treated with ESR1 protein] results in increased expression of BSP mRNA; daidzein binds to and results in increased activity of ESR1 protein; daidzein inhibits the reaction [Estradiol binds to ESR1 protein]; daidzein metabolite binds to and results in increased activity of ESR1 protein; daidzein metabolite promotes the reaction [NCOA2 protein binds to ESR1 protein]; daidzein promotes the reaction [Estradiol results in increased activity of ESR1 protein]; ESR1 protein inhibits the reaction [daidzein results in increased expression of CXCL12 mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of GREB1 mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of PGR mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of PRSS23 mRNA]; ESR1 protein inhibits the reaction [daidzein results in increased expression of TFF1 mRNA]; Estradiol affects the reaction [daidzein metabolite affects the activity of ESR1 protein]; fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein]
daidzein results in increased activity of ESR1 protein
ESR1 protein affects the susceptibility to daidzein
daidzein results in decreased expression of ESR1 mRNA; daidzein results in decreased expression of ESR1 protein
CTD PMID:9751507 PMID:12598185 PMID:12650720 PMID:14579009 PMID:15084758 PMID:15876408 PMID:16033089 PMID:16076101 PMID:16118406 PMID:16506809 PMID:16773531 PMID:16965913 PMID:18692112 PMID:19161236 PMID:19347870 PMID:19400946 PMID:19495926 PMID:19913605 PMID:23384675 PMID:24284790 PMID:25012808 PMID:29162470 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
increases expression
affects binding
affects response to substance
increases activity
ISO
EXP
[daidzein co-treated with ESR2 protein] results in decreased expression of EGFR mRNA; [daidzein co-treated with ESR2 protein] results in decreased expression of EGFR protein; [daidzein co-treated with ESR2 protein] results in increased expression of BGLAP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of BSP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; daidzein binds to and results in increased activity of ESR2 protein; daidzein inhibits the reaction [Estradiol binds to ESR2 protein]; daidzein inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein]; daidzein metabolite binds to and results in increased activity of ESR2 protein; daidzein promotes the reaction [Estradiol results in increased activity of ESR2 protein]; ESR2 affects the reaction [daidzein results in increased expression of CDKN1A]; ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein]; ESR2 gene polymorphism affects the susceptibility to [Genistein co-treated with daidzein]; Estradiol affects the reaction [daidzein metabolite affects the activity of ESR2 protein]
daidzein results in increased expression of ESR2 mRNA; daidzein results in increased expression of ESR2 protein
[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA
daidzein binds to ESR2 protein
ESR2 affects the susceptibility to daidzein
daidzein results in increased activity of ESR2 protein
daidzein results in increased activity of ESR2 protein; daidzein results in increased activity of ESR2 protein alternative form
CTD PMID:9751507 PMID:12224631 PMID:15084758 PMID:15993745 PMID:16033089 PMID:16076101 PMID:16118406 PMID:16332659 PMID:16506809 PMID:16566672 PMID:16773531 PMID:16965913 PMID:17266178 PMID:18937077 PMID:19161236 PMID:19347870 PMID:19495926 PMID:19913605 PMID:21161820 PMID:23857583 PMID:24284790 PMID:27634370 PMID:28964809 PMID:29217487 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrra estrogen related receptor, alpha multiple interactions ISO daidzein binds to and results in increased activity of ESRRA protein; daidzein binds to and results in increased activity of ESRRA protein mutant form; daidzein promotes the reaction [ESRRA protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Esrrb estrogen-related receptor beta multiple interactions ISO daidzein binds to and results in increased activity of ESRRB protein; daidzein promotes the reaction [ESRRB protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 6:110,360,940...110,458,406
Ensembl chr 6:110,410,141...110,455,906
JBrowse link
G Esrrg estrogen-related receptor gamma multiple interactions ISO daidzein promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions
increases expression
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [daidzein results in increased expression of FABP4 mRNA] CTD PMID:30920877 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:90,383,111...90,393,476
Ensembl chr10:90,383,813...90,393,317
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:62,845,054...62,860,361
Ensembl chr 4:62,844,971...62,860,446
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:170,354,109...170,364,265
Ensembl chr 3:170,354,141...170,362,513
JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:31,734,297...31,736,115
Ensembl chr20:31,734,183...31,736,212
JBrowse link
G Fermt2 FERM domain containing kindlin 2 affects expression ISO daidzein affects the expression of FERMT2 mRNA CTD PMID:15721199 NCBI chr15:19,807,806...19,876,557
Ensembl chr15:19,807,808...19,876,408
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:34,951,878...35,063,006
Ensembl chr 7:34,952,011...35,063,929
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Fmn2 formin 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of FMN2 mRNA CTD PMID:16963248 NCBI chr13:92,569,256...92,887,302 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO daidzein inhibits the reaction [Estradiol results in increased expression of FOS mRNA]
daidzein results in increased expression of FOS mRNA
CTD PMID:11473722 PMID:17142977 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:8,127,599...8,178,101
Ensembl chr16:8,128,689...8,177,841
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions EXP daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK1 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK3 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein] CTD PMID:16972265 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:252,359,976...252,368,473
Ensembl chr 2:252,359,976...252,368,473
JBrowse link
G Greb1 growth regulating estrogen receptor binding 1 increases expression
multiple interactions
ISO daidzein results in increased expression of GREB1 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of GREB1 mRNA]
CTD PMID:23384675 NCBI chr 6:41,932,941...42,002,770
Ensembl chr 6:41,932,244...42,002,819
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP daidzein inhibits the reaction [Flutamide results in decreased activity of GSR protein] CTD PMID:23135684 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:84,328,114...84,338,486
Ensembl chr 1:84,328,114...84,338,483
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:67,799,791...68,360,664
Ensembl chr13:67,799,791...68,360,664
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809
G Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 multiple interactions ISO daidzein inhibits the reaction [Colforsin results in increased expression of HSD3B2 mRNA] CTD PMID:23370353 NCBI chr 2:200,712,895...200,722,429
Ensembl chr 2:202,341,422...202,350,929
JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions ISO [daidzein co-treated with ESR1 protein] results in increased expression of BSP mRNA; [daidzein co-treated with ESR2 protein] results in increased expression of BSP mRNA CTD PMID:19347870 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Ifrd2 interferon-related developmental regulator 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IFRD2 mRNA CTD PMID:16963248 NCBI chr 8:116,343,096...116,348,318
Ensembl chr 8:116,343,096...116,348,314
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO daidzein results in decreased expression of IGF1R mRNA CTD PMID:16865672 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 increases expression ISO daidzein results in increased expression of IGFBP4 mRNA CTD PMID:15757668 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Il12a interleukin 12A multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12A mRNA] CTD PMID:21945492 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B protein] CTD PMID:21945492 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il17a interleukin 17A multiple interactions ISO daidzein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] CTD PMID:25583575 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO daidzein inhibits the reaction [Estradiol results in increased expression of IL1A mRNA] CTD PMID:11473722 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO daidzein inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
[Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]
CTD PMID:17266178 PMID:22981962 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 increases expression ISO daidzein results in increased expression of IL4 mRNA; daidzein results in increased expression of IL4 protein CTD PMID:16108819 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions ISO daidzein inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]
[Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; daidzein inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
CTD PMID:17266178 PMID:21945492 PMID:21972936 PMID:22981962 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Irf2bp1 interferon regulatory factor 2 binding protein 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of IRF2BP1 mRNA CTD PMID:16963248 NCBI chr 1:79,911,516...79,914,217
Ensembl chr 1:79,911,516...79,914,217
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:187,302,192...187,311,677
Ensembl chr 2:187,302,192...187,311,676
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO daidzein results in increased expression of JUN mRNA CTD PMID:17266178 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kat5 lysine acetyltransferase 5 multiple interactions ISO daidzein inhibits the reaction [KAT5 protein results in increased activity of ESR2 protein] CTD PMID:23857583 NCBI chr 1:220,967,795...220,974,596
Ensembl chr 1:220,967,796...220,974,597
JBrowse link
G Kcng2 potassium voltage-gated channel modifier subfamily G member 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of KCNG2 mRNA CTD PMID:16963248 NCBI chr18:76,808,294...76,880,742
Ensembl chr18:76,809,144...76,878,981
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:152,892,388...152,972,196
Ensembl chr 4:152,892,388...152,972,201
JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:110,618,256...110,638,024
Ensembl chr 3:110,618,298...110,638,046
JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 decreases expression ISO daidzein results in decreased expression of LAMP3 mRNA CTD PMID:20678512 NCBI chr11:84,930,965...85,000,694
Ensembl chr11:84,972,132...85,000,681
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:52,147,099...52,189,835
Ensembl chr13:52,147,555...52,190,228
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:89,383,515...89,399,041
Ensembl chr 1:89,383,519...89,399,041
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
AG 1879 inhibits the reaction [daidzein results in increased phosphorylation of MAPK1 protein]
daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK1 protein]; daidzein results in increased phosphorylation of and results in increased activity of MAPK1 protein
CTD PMID:16840783 PMID:16972265 PMID:24859791 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
AG 1879 inhibits the reaction [daidzein results in increased phosphorylation of MAPK3 protein]
daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK3 protein]; daidzein results in increased phosphorylation of and results in increased activity of MAPK3 protein
CTD PMID:16840783 PMID:16972265 PMID:24859791 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Me1 malic enzyme 1 increases expression ISO daidzein results in increased expression of ME1 mRNA CTD PMID:16865672 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP daidzein inhibits the reaction [Flutamide results in increased expression of MMP9 mRNA] CTD PMID:23135684 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:26,130,278...26,138,498
Ensembl chr 6:26,130,488...26,138,414
JBrowse link
G Mt2A metallothionein 2A increases expression ISO daidzein results in increased expression of MT2A mRNA CTD PMID:10656621 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:198,301,666...198,311,787
Ensembl chr 2:198,303,168...198,311,785
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO daidzein results in increased expression of MYC mRNA CTD PMID:17266178 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:256,585,410...256,734,727
Ensembl chr 1:256,585,410...256,734,730
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO [daidzein binds to THRB protein] promotes the reaction [NCOA1 protein binds to THRB protein]; daidzein promotes the reaction [NCOA1 protein binds to THRB protein] CTD PMID:29688519 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO daidzein metabolite promotes the reaction [NCOA2 protein binds to ESR1 protein] CTD PMID:15084758 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased localization of NFKB1 protein] CTD PMID:21972936 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:21972936 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nkx3-1 NK3 homeobox 1 decreases expression ISO daidzein results in decreased expression of NKX3-1 mRNA CTD PMID:16865672 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases activity
ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]
daidzein results in decreased activity of NOS2 protein
CTD PMID:11308324 PMID:18274639 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 increases activity ISO daidzein results in increased activity of NOS3 protein CTD PMID:16840783 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO daidzein results in decreased expression of NQO1 mRNA CTD PMID:18497090 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO daidzein binds to and results in increased activity of NR1I2 protein CTD PMID:16054614 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 increases expression ISO daidzein results in increased expression of NRIP1 mRNA CTD PMID:15757668 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563
JBrowse link
G Olfml3 olfactomedin-like 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of OLFML3 mRNA CTD PMID:16963248 NCBI chr 2:206,219,419...206,222,248
Ensembl chr 2:206,219,419...206,222,248
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO daidzein results in increased cleavage of PARP1 protein CTD PMID:12791511 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO
EXP
daidzein results in decreased expression of PCNA
daidzein results in decreased expression of PCNA protein
CTD PMID:21161820 PMID:29217487 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdlim2 PDZ and LIM domain 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PDLIM2 mRNA CTD PMID:16963248 NCBI chr15:51,843,562...51,856,785
Ensembl chr15:51,843,564...51,855,325
JBrowse link
G Pdzk1 PDZ domain containing 1 increases expression ISO daidzein results in increased expression of PDZK1 mRNA CTD PMID:15757668 NCBI chr 2:198,965,685...198,999,323
Ensembl chr 2:198,965,685...198,999,323
JBrowse link
G Pgr progesterone receptor increases expression
multiple interactions
ISO daidzein results in increased expression of PGR mRNA; daidzein results in increased expression of PGR protein
ESR1 protein inhibits the reaction [daidzein results in increased expression of PGR mRNA]
CTD PMID:17142977 PMID:23384675 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions EXP daidzein inhibits the reaction [Flutamide results in increased expression of PLAUR mRNA] CTD PMID:23135684 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Plcb2 phospholipase C, beta 2 multiple interactions EXP daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK1 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein results in increased activity of MAPK3 protein]; daidzein promotes the reaction [GNB1 protein results in increased activity of PLCB2 protein] CTD PMID:16972265 NCBI chr 3:110,497,760...110,517,563
Ensembl chr 3:110,498,114...110,517,163
JBrowse link
G Pnn pinin, desmosome associated protein multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of PNN mRNA CTD PMID:16963248 NCBI chr 6:80,159,364...80,167,677
Ensembl chr 6:80,159,364...80,167,677
JBrowse link
G Pnrc1 proline-rich nuclear receptor coactivator 1 multiple interactions ISO daidzein promotes the reaction [ESRRA protein binds to PNRC1 protein]; daidzein promotes the reaction [ESRRB protein binds to PNRC1 protein]; daidzein promotes the reaction [ESRRG protein binds to PNRC1 protein] CTD PMID:14638870 NCBI chr 5:48,501,472...48,504,511
Ensembl chr 5:48,501,472...48,504,511
JBrowse link
G Pou4f2 POU class 4 homeobox 2 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of POU4F2 mRNA CTD PMID:16963248 NCBI chr19:33,160,180...33,163,821
Ensembl chr19:33,160,180...33,163,821
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkca protein kinase C, alpha increases activity EXP daidzein results in increased activity of PRKCA protein CTD PMID:16972265 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcb protein kinase C, beta increases activity EXP daidzein results in increased activity of PRKCB protein CTD PMID:16972265 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcd protein kinase C, delta decreases expression ISO daidzein results in decreased expression of PRKCD mRNA CTD PMID:15757668 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP daidzein affects the localization of and results in increased activity of PRKCE protein CTD PMID:16972265 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkcg protein kinase C, gamma increases activity EXP daidzein results in increased activity of PRKCG protein CTD PMID:16972265 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Prl prolactin increases secretion EXP daidzein results in increased secretion of PRL protein CTD PMID:19400946 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:38,680,583...38,741,570
Ensembl chr 3:38,682,146...38,741,113
JBrowse link
G Prss23 serine protease 23 increases expression
multiple interactions
ISO daidzein results in increased expression of PRSS23 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of PRSS23 mRNA]
CTD PMID:23384675 NCBI chr 1:153,732,528...153,742,111
Ensembl chr 1:153,732,532...153,752,541
JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:36,946,914...37,030,273
Ensembl chr15:36,950,257...37,030,281
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [daidzein co-treated with ESR2 protein] results in increased expression of PTGS2 mRNA; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
CTD PMID:16870006 PMID:19347870 PMID:21341175 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Ptk2 protein tyrosine kinase 2 increases phosphorylation ISO daidzein results in increased phosphorylation of PTK2 protein CTD PMID:12421874 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Rac1 Rac family small GTPase 1 increases activity ISO daidzein results in increased activity of RAC1 protein CTD PMID:24859791 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:47,956,754...48,022,333
Ensembl chr13:47,956,790...48,022,333
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease increases expression ISO daidzein results in increased expression of RBBP8 mRNA CTD PMID:15757668 NCBI chr18:3,134,630...3,227,702
Ensembl chr18:3,162,543...3,227,688
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein] CTD PMID:18274639 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:74,783,009...74,902,049
Ensembl chr 7:74,783,019...74,901,997
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 increases expression ISO daidzein results in increased expression of RPS6KA3 mRNA CTD PMID:15757668 NCBI chr  X:37,469,736...37,576,055
Ensembl chr  X:37,469,937...37,575,624
JBrowse link
G RT1-Bb RT1 class II, locus Bb multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of H2-AB1 protein] CTD PMID:21945492 NCBI chr20:4,043,726...4,049,367
Ensembl chr20:4,039,413...4,049,711
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,799,383...13,812,877
Ensembl chr17:13,799,383...13,812,704
JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:48,577,905...48,579,196
Ensembl chr12:48,577,905...48,579,196
JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of SGPP1 mRNA CTD PMID:16963248 NCBI chr 6:98,675,324...98,696,492
Ensembl chr 6:98,675,326...98,695,988
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:98,512,663...98,521,736
Ensembl chr 1:98,512,625...98,521,706
JBrowse link
G Slc10a1 solute carrier family 10 member 1 multiple interactions
increases transport
ISO daidzein metabolite inhibits the reaction [SLC10A1 protein results in increased transport of estrone sulfate]; daidzein metabolite promotes the reaction [SLC10A1 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLC10A1 protein results in increased transport of daidzein metabolite]; Taurocholic Acid inhibits the reaction [SLC10A1 protein results in increased transport of daidzein metabolite] CTD PMID:25319728 NCBI chr 6:104,617,730...104,631,355
Ensembl chr 6:104,617,730...104,631,355
JBrowse link
G Slc10a6 solute carrier family 10 member 6 multiple interactions
increases transport
ISO daidzein inhibits the reaction [SLC10A6 protein results in increased transport of estrone sulfate]; daidzein metabolite inhibits the reaction [SLC10A6 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLC10A6 protein results in increased transport of daidzein metabolite] CTD PMID:25319728 NCBI chr14:7,618,022...7,682,377
Ensembl chr14:7,618,022...7,682,377
JBrowse link
G Slc12a2 solute carrier family 12 member 2 decreases expression ISO daidzein results in decreased expression of SLC12A2 mRNA CTD PMID:15757668 NCBI chr18:52,917,124...52,985,281
Ensembl chr18:52,917,124...52,985,261
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases uptake ISO SLC22A8 protein results in increased uptake of daidzein analog CTD PMID:21244849 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
decreases activity
ISO daidzein inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
daidzein results in decreased activity of SLC2A1 protein
CTD PMID:14642735 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc7a5 solute carrier family 7 member 5 increases expression ISO daidzein results in increased expression of SLC7A5 mRNA CTD PMID:15757668 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions
increases transport
ISO daidzein inhibits the reaction [SLCO2B1 protein results in increased transport of estrone sulfate]; daidzein metabolite inhibits the reaction [SLCO2B1 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLCO2B1 protein results in increased transport of daidzein metabolite] CTD PMID:25319728 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:77,052,445...77,161,964
Ensembl chr 5:77,052,484...77,157,915
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
affects response to substance
multiple interactions
ISO daidzein results in increased expression of SOD2 protein
SOD2 protein affects the susceptibility to daidzein
fulvestrant inhibits the reaction [daidzein results in increased expression of SOD2 protein]
CTD PMID:23526725 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:72,443,750...72,462,293
Ensembl chr 1:72,443,758...72,461,547
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO daidzein inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]; daidzein inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein] CTD PMID:18274639 PMID:21972936 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stc1 stanniocalcin 1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of STC1 mRNA CTD PMID:16963248 NCBI chr15:50,891,137...50,901,791
Ensembl chr15:50,891,127...50,903,162
JBrowse link
G Stk39 serine threonine kinase 39 decreases expression ISO daidzein results in decreased expression of STK39 mRNA CTD PMID:16865672 NCBI chr 3:54,359,449...54,625,702
Ensembl chr 3:54,359,451...54,625,414
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:23,954,563...23,987,155
Ensembl chr12:23,954,574...23,987,271
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO daidzein inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol] CTD PMID:15531517 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Tacr3 tachykinin receptor 3 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in increased expression of TACR3 mRNA CTD PMID:16963248 NCBI chr 2:240,021,152...240,118,971
Ensembl chr 2:240,021,152...240,118,971
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:125,437,767...125,601,408
Ensembl chr 6:125,437,775...125,590,049
JBrowse link
G Tff1 trefoil factor 1 increases expression
multiple interactions
ISO daidzein results in increased expression of TFF1 mRNA
ESR1 protein inhibits the reaction [daidzein results in increased expression of TFF1 mRNA]
CTD PMID:16965913 PMID:23384675 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tg thyroglobulin decreases expression EXP daidzein results in decreased expression of TG mRNA CTD PMID:24793811 NCBI chr 7:107,467,260...107,652,897
Ensembl chr 7:107,467,260...107,652,899
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 multiple interactions ISO daidzein promotes the reaction [TGFB1I1 protein results in increased activity of AR protein] CTD PMID:17252558 NCBI chr 1:199,664,039...199,670,970
Ensembl chr 1:199,664,173...199,670,961
JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO daidzein results in increased expression of TGM2 mRNA; daidzein results in increased expression of TGM2 protein CTD PMID:24859791 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions
affects binding
ISO daidzein promotes the reaction [Triiodothyronine results in increased activity of THRA protein]
daidzein binds to THRA protein
CTD PMID:29688519 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO [daidzein binds to THRB protein] promotes the reaction [NCOA1 protein binds to THRB protein]; daidzein promotes the reaction [NCOA1 protein binds to THRB protein]; daidzein promotes the reaction [Triiodothyronine results in increased activity of THRB protein] CTD PMID:29688519 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Thrsp thyroid hormone responsive increases expression EXP daidzein results in increased expression of THRSP mRNA CTD PMID:24793811 NCBI chr 1:162,381,251...162,385,575
Ensembl chr 1:162,381,253...162,385,575
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; daidzein inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:21945492 PMID:22981962 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of TNFAIP6 mRNA CTD PMID:16963248 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
G Tp53 tumor protein p53 increases expression ISO daidzein results in increased expression of TP53 protein CTD PMID:19800779 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 decreases expression
multiple interactions
ISO daidzein results in decreased expression of TP53I11 mRNA
[daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA
CTD PMID:15757668 PMID:27424125 NCBI chr 3:82,081,838...82,097,064
Ensembl chr 3:82,081,906...82,097,056
JBrowse link
G Tpd52l1 TPD52 like 1 increases expression ISO daidzein results in increased expression of TPD52L1 mRNA CTD PMID:15757668 NCBI chr 1:28,454,949...28,578,736
Ensembl chr 1:28,454,966...28,576,553
JBrowse link
G Tpo thyroid peroxidase decreases expression
decreases activity
EXP
ISO
daidzein results in decreased expression of TPO mRNA
daidzein results in decreased activity of TPO protein
CTD PMID:24793811 PMID:31629072 NCBI chr 6:49,020,918...49,089,855
Ensembl chr 6:49,021,044...49,089,855
JBrowse link
G Tyr tyrosinase increases expression ISO daidzein results in increased expression of TYR mRNA CTD PMID:21071833 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO [Genistein co-treated with daidzein co-treated with glycitein] results in decreased expression of UCHL1 mRNA CTD PMID:16963248 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation
increases activity
ISO UGT1A1 protein results in increased glucuronidation of daidzein
daidzein results in increased activity of UGT1A1 protein
CTD PMID:14557274 PMID:16051636 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of daidzein CTD PMID:14557274 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of daidzein CTD PMID:14557274 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression ISO daidzein results in increased expression of UGT2B17 mRNA CTD PMID:16865672 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ESR2 gene polymorphism affects the reaction [[Genistein co-treated with daidzein] affects the expression of VCAM1 protein] CTD PMID:16332659 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:9,231,180...9,257,821
Ensembl chr 5:9,230,984...9,257,934
JBrowse link
daidzein 7-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases expression
multiple interactions
EXP daidzin results in increased expression of ACHE mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of ACHE mRNA]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of and results in increased activity of ACHE protein]; daidzin results in increased expression of and results in increased activity of ACHE protein
CTD PMID:31034797 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of ACSL3 mRNA CTD PMID:27424125 NCBI chr 9:84,569,601...84,593,565
Ensembl chr 9:84,569,597...84,593,565
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ALDH1A2 mRNA CTD PMID:27424125 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO daidzin inhibits the reaction [ALDH2 protein results in increased hydrolysis of 4-nitrophenyl acetate]; daidzin inhibits the reaction [ALDH2 protein results in increased oxidation of propionaldehyde] CTD PMID:21349255 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ANPEP mRNA CTD PMID:27424125 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Atoh8 atonal bHLH transcription factor 8 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of ATOH8 mRNA CTD PMID:27424125 NCBI chr 4:100,067,341...100,099,517
Ensembl chr 4:100,067,341...100,099,517
JBrowse link
G Bckdk branched chain ketoacid dehydrogenase kinase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of BCKDK mRNA CTD PMID:27424125 NCBI chr 1:199,351,628...199,356,299
Ensembl chr 1:199,351,628...199,356,881
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of BDNF protein] CTD PMID:32450180 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bpgm bisphosphoglycerate mutase multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of BPGM mRNA CTD PMID:27424125 NCBI chr 4:61,912,210...61,940,697
Ensembl chr 4:61,912,210...61,940,696
JBrowse link
G Cabp5 calcium binding protein 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CABP5 mRNA CTD PMID:27424125 NCBI chr 1:75,693,216...75,706,069
Ensembl chr 1:75,693,232...75,706,069
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CACYBP mRNA CTD PMID:27424125 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CASP8AP2 mRNA CTD PMID:27424125 NCBI chr 5:47,853,699...47,891,147
Ensembl chr 5:47,853,818...47,891,668
JBrowse link
G Cat catalase multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased activity of CAT protein] CTD PMID:32450180 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cd200r1 CD200 receptor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CD200R1 mRNA CTD PMID:27424125 NCBI chr11:60,848,161...60,882,470
Ensembl chr11:60,848,131...60,882,379
JBrowse link
G Cfap251 cilia and flagella associated protein 251 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of CFAP251 mRNA CTD PMID:27424125 NCBI chr12:38,708,915...38,781,598
Ensembl chr12:38,709,595...38,782,010
JBrowse link
G Cybrd1 cytochrome b reductase 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of CYBRD1 mRNA CTD PMID:27424125 NCBI chr 3:57,718,496...57,745,749
Ensembl chr 3:57,718,364...57,746,097
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of CYP11A1 mRNA CTD PMID:28964809 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Dennd2d DENN domain containing 2D multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of DENND2D mRNA CTD PMID:27424125 NCBI chr 2:209,097,894...209,116,978
Ensembl chr 2:209,097,927...209,116,965
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT1 mRNA CTD PMID:28964809 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of DNMT3A mRNA CTD PMID:28964809 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dpp9 dipeptidyl peptidase 9 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of DPP9 mRNA CTD PMID:27424125 NCBI chr 9:10,846,493...10,882,560
Ensembl chr 9:10,846,596...10,882,649
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of EDRF1 mRNA CTD PMID:27424125 NCBI chr 1:205,706,023...205,743,676
Ensembl chr 1:205,706,468...205,743,653
JBrowse link
G Efhd1 EF-hand domain family, member D1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of EFHD1 mRNA CTD PMID:27424125 NCBI chr 9:94,362,249...94,408,884
Ensembl chr 9:94,362,299...94,408,885
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased expression of ESR2 mRNA CTD PMID:28964809 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fam171a2 family with sequence similarity 171, member A2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FAM171A2 mRNA CTD PMID:27424125 NCBI chr10:90,383,111...90,393,476
Ensembl chr10:90,383,813...90,393,317
JBrowse link
G Fam180a family with sequence similarity 180, member A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM180A mRNA CTD PMID:27424125 NCBI chr 4:62,845,054...62,860,361
Ensembl chr 4:62,844,971...62,860,446
JBrowse link
G Fam210b family with sequence similarity 210, member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FAM210B mRNA CTD PMID:27424125 NCBI chr 3:170,354,109...170,364,265
Ensembl chr 3:170,354,141...170,362,513
JBrowse link
G Fam241b family with sequence similarity 241 member B multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of FAM241B mRNA CTD PMID:27424125 NCBI chr20:31,734,297...31,736,115
Ensembl chr20:31,734,183...31,736,212
JBrowse link
G Fgd6 FYVE, RhoGEF and PH domain containing 6 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of FGD6 mRNA CTD PMID:27424125 NCBI chr 7:34,951,878...35,063,006
Ensembl chr 7:34,952,011...35,063,929
JBrowse link
G Fhl2 four and a half LIM domains 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of FHL2 mRNA CTD PMID:27424125 NCBI chr 9:49,920,611...49,994,906
Ensembl chr 9:49,920,854...49,950,093
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO daidzin results in increased expression of FOS mRNA CTD PMID:17142977 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Galnt15 polypeptide N-acetylgalactosaminyltransferase 15 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of GALNT15 mRNA CTD PMID:27424125 NCBI chr16:8,127,599...8,178,101
Ensembl chr16:8,128,689...8,177,841
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of GNG5 mRNA CTD PMID:27424125 NCBI chr 2:252,359,976...252,368,473
Ensembl chr 2:252,359,976...252,368,473
JBrowse link
G Hipk4 homeodomain interacting protein kinase 4 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of HIPK4 mRNA CTD PMID:27424125 NCBI chr 1:84,328,114...84,338,486
Ensembl chr 1:84,328,114...84,338,483
JBrowse link
G Hmcn1 hemicentin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of HMCN1 mRNA CTD PMID:27424125 NCBI chr13:67,799,791...68,360,664
Ensembl chr13:67,799,791...68,360,664
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in decreased expression of HMOX1 protein] CTD PMID:32450180 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of HSD3B1 mRNA CTD PMID:28964809
G Il6r interleukin 6 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of IL6R mRNA CTD PMID:27424125 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Isg20l2 interferon stimulated exonuclease gene 20-like 2 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of ISG20L2 mRNA CTD PMID:27424125 NCBI chr 2:187,302,192...187,311,677
Ensembl chr 2:187,302,192...187,311,676
JBrowse link
G Kdm5a lysine demethylase 5A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of KDM5A mRNA CTD PMID:27424125 NCBI chr 4:152,892,388...152,972,196
Ensembl chr 4:152,892,388...152,972,201
JBrowse link
G Kitlg KIT ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KITLG mRNA CTD PMID:27424125 NCBI chr 7:42,269,784...42,351,054
Ensembl chr 7:42,269,784...42,351,054
JBrowse link
G Knstrn kinetochore-localized astrin/SPAG5 binding protein multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of KNSTRN mRNA CTD PMID:27424125 NCBI chr 3:110,618,256...110,638,024
Ensembl chr 3:110,618,298...110,638,046
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LDLRAP1 mRNA CTD PMID:27424125 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211
JBrowse link
G Lmod1 leiomodin 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LMOD1 mRNA CTD PMID:27424125 NCBI chr13:52,147,099...52,189,835
Ensembl chr13:52,147,555...52,190,228
JBrowse link
G Lrg1 leucine-rich alpha-2-glycoprotein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of LRG1 mRNA CTD PMID:27424125 NCBI chr 9:10,952,424...10,954,664
Ensembl chr 9:10,952,374...10,954,681
JBrowse link
G Lsr lipolysis stimulated lipoprotein receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of LSR mRNA CTD PMID:27424125 NCBI chr 1:89,383,515...89,399,041
Ensembl chr 1:89,383,519...89,399,041
JBrowse link
G Mrpl33 mitochondrial ribosomal protein L33 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of MRPL33 mRNA CTD PMID:27424125 NCBI chr 6:26,130,278...26,138,498
Ensembl chr 6:26,130,488...26,138,414
JBrowse link
G Mtmr11 myotubularin related protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of MTMR11 mRNA CTD PMID:27424125 NCBI chr 2:198,301,666...198,311,787
Ensembl chr 2:198,303,168...198,311,785
JBrowse link
G Myof myoferlin multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of MYOF mRNA CTD PMID:27424125 NCBI chr 1:256,585,410...256,734,727
Ensembl chr 1:256,585,410...256,734,730
JBrowse link
G Nefh neurofilament heavy increases expression EXP daidzin results in increased expression of NEFH mRNA; daidzin results in increased expression of NEFH protein CTD PMID:31034797 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light increases expression EXP daidzin results in increased expression of NEFL mRNA; daidzin results in increased expression of NEFL protein CTD PMID:31034797 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of NR4A1 mRNA CTD PMID:27424125 NCBI chr 7:142,899,358...142,920,216
Ensembl chr 7:142,905,758...142,920,216
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 protein; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in increased methylation of NR5A1 promoter; decitabine inhibits the reaction [[Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of NR5A1 mRNA] CTD PMID:28964809 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Pgr progesterone receptor increases expression ISO daidzin results in increased expression of PGR protein CTD PMID:17142977 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Prima1 proline rich membrane anchor 1 increases expression
multiple interactions
EXP daidzin results in increased expression of PRIMA1 mRNA
4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [daidzin results in increased expression of PRIMA1 mRNA]
CTD PMID:31034797 NCBI chr 6:127,075,954...127,127,985
Ensembl chr 6:127,075,954...127,127,413
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of PRKACA mRNA CTD PMID:27424125 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PRPF40A mRNA CTD PMID:27424125 NCBI chr 3:38,680,583...38,741,570
Ensembl chr 3:38,682,146...38,741,113
JBrowse link
G Pspc1 paraspeckle component 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of PSPC1 mRNA CTD PMID:27424125 NCBI chr15:36,946,914...37,030,273
Ensembl chr15:36,950,257...37,030,281
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of PTH1R mRNA CTD PMID:27424125 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Rassf5 Ras association domain family member 5 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of RASSF5 mRNA CTD PMID:27424125 NCBI chr13:47,956,754...48,022,333
Ensembl chr13:47,956,790...48,022,333
JBrowse link
G Rgs22 regulator of G-protein signaling 22 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of RGS22 mRNA CTD PMID:27424125 NCBI chr 7:74,783,009...74,902,049
Ensembl chr 7:74,783,019...74,901,997
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of S1PR3 mRNA CTD PMID:27424125 NCBI chr17:13,799,383...13,812,877
Ensembl chr17:13,799,383...13,812,704
JBrowse link
G Selplg selectin P ligand multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SELPLG mRNA CTD PMID:27424125 NCBI chr12:48,577,905...48,579,196
Ensembl chr12:48,577,905...48,579,196
JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SIGLEC10 mRNA CTD PMID:27424125 NCBI chr 1:98,512,663...98,521,736
Ensembl chr 1:98,512,625...98,521,706
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SLC16A1 mRNA CTD PMID:27424125 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Snx30 sorting nexin family member 30 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of SNX30 mRNA CTD PMID:27424125 NCBI chr 5:77,052,445...77,161,964
Ensembl chr 5:77,052,484...77,157,915
JBrowse link
G Ssc5d scavenger receptor cysteine rich family member with 5 domains multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] affects the expression of SSC5D mRNA CTD PMID:27424125 NCBI chr 1:72,443,750...72,462,293
Ensembl chr 1:72,443,758...72,461,547
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR mRNA; [Genistein co-treated with daidzein co-treated with glycitin co-treated with genistin co-treated with daidzin co-treated with glycitein] results in decreased expression of STAR protein CTD PMID:28964809 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of STYXL1 mRNA CTD PMID:27424125 NCBI chr12:23,954,563...23,987,155
Ensembl chr12:23,954,574...23,987,271
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of SUMO1 mRNA CTD PMID:27424125 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Tc2n tandem C2 domains, nuclear multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of TC2N mRNA CTD PMID:27424125 NCBI chr 6:125,437,767...125,601,408
Ensembl chr 6:125,437,775...125,590,049
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in decreased expression of TP53I11 mRNA CTD PMID:27424125 NCBI chr 3:82,081,838...82,097,064
Ensembl chr 3:82,081,906...82,097,056
JBrowse link
G Vcpip1 valosin containing protein interacting protein 1 multiple interactions ISO [daidzein co-treated with daidzin co-treated with genistin co-treated with Genistein co-treated with glycitin co-treated with glycitein] results in increased expression of VCPIP1 mRNA CTD PMID:27424125 NCBI chr 5:9,231,180...9,257,821
Ensembl chr 5:9,230,984...9,257,934
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO daidzin inhibits the reaction [Pentylenetetrazole results in increased expression of VEGFA protein] CTD PMID:32450180 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
ellagic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp3 acid phosphatase 3 increases expression ISO Ellagic Acid results in increased expression of ACP3 mRNA CTD PMID:12002526 NCBI chr 8:112,838,574...112,884,062
Ensembl chr 8:112,834,707...112,884,077
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Ellagic Acid results in increased expression of AIFM1 protein CTD PMID:23554011 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Ellagic Acid results in increased phosphorylation of AKT1 protein CTD PMID:26986492 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin multiple interactions
affects binding
ISO ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein]
Ellagic Acid binds to ALB protein
CTD PMID:6343536 PMID:25247703 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase decreases activity ISO Ellagic Acid results in decreased activity of ALKBH2 protein CTD PMID:31088072 NCBI chr12:48,257,575...48,262,244
Ensembl chr12:48,257,609...48,262,243
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO Ellagic Acid results in decreased expression of APAF1 mRNA CTD PMID:12002526 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 increases expression ISO Ellagic Acid results in increased expression of ASCL1 mRNA CTD PMID:12002526 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Ellagic Acid results in increased expression of ASNS mRNA CTD PMID:12002526 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Ellagic Acid results in increased expression of ATF3 mRNA CTD PMID:12002526 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atg5 autophagy related 5 increases expression ISO Ellagic Acid results in increased expression of ATG5 mRNA CTD PMID:12002526 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Ellagic Acid results in increased expression of BAD protein CTD PMID:23554011 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of BAX mRNA] CTD PMID:29854611 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
multiple interactions
ISO
EXP
Ellagic Acid results in increased expression of BCL2 protein
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of BCL2 mRNA]
[Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of BCL2 mRNA]
CTD PMID:20103723 PMID:22386815 PMID:29854611 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Ellagic Acid results in decreased expression of BMP6 mRNA CTD PMID:12002526 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit decreases expression ISO Ellagic Acid results in decreased expression of BRF1 mRNA CTD PMID:12002526 NCBI chr 6:137,762,230...137,808,573
Ensembl chr 6:137,765,122...137,808,303
JBrowse link
G Calr calreticulin decreases expression ISO Ellagic Acid results in decreased expression of CALR mRNA CTD PMID:12002526 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Casp3 caspase 3 increases expression
multiple interactions
increases activity
decreases activity
decreases expression
ISO
EXP
Ellagic Acid results in increased expression of CASP3 mRNA
Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased activity of CASP3 protein]
Ellagic Acid results in increased expression of and results in increased activity of CASP3 protein
Ellagic Acid results in increased activity of CASP3 protein
Ellagic Acid results in decreased activity of CASP3 protein
Ellagic Acid results in decreased expression of CASP3 mRNA
CTD PMID:12002526 PMID:22386815 PMID:23554011 PMID:23811531 PMID:28815802 PMID:29854611 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Ellagic Acid results in increased expression of and results in increased activity of CASP9 protein CTD PMID:23554011 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases activity
multiple interactions
EXP Ellagic Acid results in increased activity of CAT protein
Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:20074268 PMID:24877639 PMID:29864931 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases secretion ISO Ellagic Acid results in decreased secretion of CCL2 protein CTD PMID:20816778 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cd14 CD14 molecule decreases expression ISO Ellagic Acid results in decreased expression of CD14 mRNA CTD PMID:20816778 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Ellagic Acid results in decreased expression of CDK1 protein CTD PMID:23554011 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CDKN1A mRNA]
[Ellagic Acid co-treated with Quercetin] results in increased expression of CDKN1A mRNA; Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased expression of CDKN1A protein]]
Ellagic Acid results in increased expression of CDKN1A protein
CTD PMID:15735102 PMID:20103723 PMID:23554011 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ctsd cathepsin D multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:21762681 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
decreases activity
ISO Ellagic Acid results in decreased expression of CYP1A1 mRNA
Ellagic Acid results in decreased activity of CYP1A1 protein
CTD PMID:19329757 PMID:20816778 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
multiple interactions
ISO Ellagic Acid results in decreased activity of CYP1B1 protein
[Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of CYP1B1 mRNA]
CTD PMID:19329757 PMID:20103723 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Daxx death-domain associated protein decreases expression ISO Ellagic Acid results in decreased expression of DAXX mRNA CTD PMID:12002526 NCBI chr20:5,480,103...5,485,962
Ensembl chr20:5,480,103...5,485,926
JBrowse link
G Dffa DNA fragmentation factor subunit alpha decreases expression ISO Ellagic Acid results in decreased expression of DFFA mRNA CTD PMID:12002526 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G E4f1 E4F transcription factor 1 increases expression ISO Ellagic Acid results in increased expression of E4F1 mRNA CTD PMID:12002526 NCBI chr10:13,812,335...13,835,847
Ensembl chr10:13,815,293...13,826,945
JBrowse link
G Egr3 early growth response 3 decreases expression ISO Ellagic Acid results in decreased expression of EGR3 mRNA CTD PMID:12002526 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Endog endonuclease G increases expression ISO Ellagic Acid results in increased expression of ENDOG protein CTD PMID:23554011 NCBI chr 3:8,741,833...8,744,414
Ensembl chr 3:8,741,766...8,744,592
JBrowse link
G Ep300 E1A binding protein p300 increases expression ISO Ellagic Acid results in increased expression of EP300 mRNA CTD PMID:12002526 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 increases expression ISO Ellagic Acid results in increased expression of EPS15 mRNA CTD PMID:12002526 NCBI chr 5:128,923,809...129,022,268
Ensembl chr 5:128,923,934...129,022,054
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit increases expression ISO Ellagic Acid results in increased expression of EZH1 mRNA CTD PMID:12002526 NCBI chr10:89,104,026...89,139,978
Ensembl chr10:89,104,027...89,130,339
JBrowse link
G F12 coagulation factor XII multiple interactions
increases activity
ISO ALB protein promotes the reaction [Ellagic Acid results in increased activity of F12 protein] CTD PMID:6343536 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Ellagic Acid results in decreased expression of FGFR1 mRNA CTD PMID:12002526 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Flna filamin A decreases expression ISO Ellagic Acid results in decreased expression of FLNA mRNA CTD PMID:12002526 NCBI chr  X:156,460,785...156,487,245
Ensembl chr  X:156,463,953...156,487,245
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] CTD PMID:24877639 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of FOS mRNA] CTD PMID:20103723 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Ellagic Acid results in decreased activity of G6PD protein CTD PMID:25130191 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased activity of GAL protein] CTD PMID:27965107 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 decreases expression ISO Ellagic Acid results in decreased expression of GPLD1 mRNA CTD PMID:12002526 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of GPT protein] CTD PMID:24877639 PMID:29935397 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of GPX1 mRNA] CTD PMID:29935397 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein] CTD PMID:24877639 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression ISO Ellagic Acid results in increased expression of GSTA4 mRNA CTD PMID:12002526 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Ellagic Acid affects the expression of GSTT1 protein CTD PMID:9855024 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gtf2e2 general transcription factor IIE subunit 2 increases expression ISO Ellagic Acid results in increased expression of GTF2E2 mRNA CTD PMID:12002526 NCBI chr16:62,113,846...62,164,339
Ensembl chr16:62,113,854...62,164,135
JBrowse link
G Gtf2h4 general transcription factor 2H subunit 4 increases expression ISO Ellagic Acid results in increased expression of GTF2H4 mRNA CTD PMID:12002526 NCBI chr20:3,582,688...3,588,373
Ensembl chr20:3,582,742...3,588,375
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:21762681 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Ellagic Acid results in decreased expression of HIF1A mRNA CTD PMID:12002526 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO Ellagic Acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of HMOX1 mRNA; Ellagic Acid results in increased expression of HMOX1 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 protein
CTD PMID:22386815 PMID:23546295 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [Ellagic Acid co-treated with Plant Extracts] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene]; [Ellagic Acid co-treated with resveratrol] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased mutagenesis of HRAS gene] CTD PMID:20103723 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Ier2 immediate early response 2 increases expression ISO Ellagic Acid results in increased expression of IER2 mRNA CTD PMID:12002526 NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
JBrowse link
G Ifng interferon gamma multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IFNG protein] CTD PMID:29854611 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO Ellagic Acid results in increased expression of IGFBP2 mRNA CTD PMID:12002526 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression ISO Ellagic Acid results in decreased expression of IGFBP4 mRNA CTD PMID:12002526 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO
EXP
Ellagic Acid results in decreased expression of IL1B mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL1B protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of IL1B protein]
Ellagic Acid inhibits the reaction [IL1B protein results in increased secretion of CXCL8 protein]
CTD PMID:18377686 PMID:20816778 PMID:21762681 PMID:24877639 PMID:27965107 PMID:29455002 PMID:29854611 PMID:29864931 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r1 interleukin 1 receptor type 1 decreases expression ISO Ellagic Acid results in decreased expression of IL1R1 mRNA CTD PMID:20816778 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of IL6 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of IL6 protein] CTD PMID:21762681 PMID:24877639 PMID:27965107 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D increases expression ISO Ellagic Acid results in increased expression of INPP5D mRNA CTD PMID:12002526 NCBI chr 9:94,745,220...94,850,778
Ensembl chr 9:94,745,217...94,850,771
JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 increases expression ISO Ellagic Acid results in increased expression of IQGAP2 mRNA CTD PMID:12002526 NCBI chr 2:26,161,628...26,439,067
Ensembl chr 2:26,167,199...26,438,790
JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO Ellagic Acid results in increased expression of IRF9 mRNA CTD PMID:12002526 NCBI chr15:34,282,936...34,288,981
Ensembl chr15:34,282,936...34,288,138
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Ellagic Acid results in decreased expression of JUN mRNA; Ellagic Acid results in decreased expression of JUN protein modified form CTD PMID:23811531 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Litaf lipopolysaccharide-induced TNF factor increases expression ISO Ellagic Acid results in increased expression of LITAF mRNA CTD PMID:12002526 NCBI chr10:4,753,546...4,763,272
Ensembl chr10:4,719,713...4,763,510
JBrowse link
G Map1a microtubule-associated protein 1A decreases expression ISO Ellagic Acid results in decreased expression of MAP1A mRNA CTD PMID:12002526 NCBI chr 3:113,251,918...113,272,193
Ensembl chr 3:113,251,778...113,272,186
JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 decreases expression ISO Ellagic Acid results in decreased expression of MAP3K1 mRNA; Ellagic Acid results in decreased expression of MAP3K1 protein CTD PMID:23811531 NCBI chr 2:43,329,516...43,393,203
Ensembl chr 2:43,329,516...43,393,207
JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression ISO Ellagic Acid results in increased expression of MAPK11 mRNA CTD PMID:23811531 NCBI chr 7:130,121,678...130,129,199
Ensembl chr 7:130,121,687...130,128,604
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased expression of MAPK14 protein] CTD PMID:27965107 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK8 protein CTD PMID:15735102 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Ellagic Acid co-treated with Quercetin] results in increased phosphorylation of MAPK9 protein CTD PMID:15735102 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases activity EXP Ellagic Acid results in decreased activity of MGST1 protein CTD PMID:16125204 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression ISO Ellagic Acid results in increased expression of MMD mRNA CTD PMID:12002526 NCBI chr10:77,687,964...77,783,737
Ensembl chr10:77,755,216...77,783,779
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein; zinc chloride inhibits the reaction [Ellagic Acid results in decreased activity of and results in decreased secretion of MMP2 protein] CTD PMID:21573219 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization
increases expression
multiple interactions
affects response to substance
ISO Ellagic Acid affects the localization of NFE2L2 protein
Ellagic Acid results in increased expression of NFE2L2 mRNA
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of NFE2L2 mRNA]
[Paraquat co-treated with Ellagic Acid] results in increased expression of and affects the localization of NFE2L2 protein; [Paraquat co-treated with Ellagic Acid] results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of and affects the localization of NFE2L2 protein
Ellagic Acid results in increased expression of NFE2L2 mRNA; Ellagic Acid results in increased expression of NFE2L2 protein
NFE2L2 protein affects the susceptibility to Ellagic Acid
CTD PMID:22386815 PMID:23546295 PMID:30503583 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 decreases expression ISO Ellagic Acid results in decreased expression of NFKB2 mRNA CTD PMID:12002526 NCBI chr 1:266,050,634...266,059,277
Ensembl chr 1:266,053,002...266,059,256
JBrowse link
G Nnat neuronatin increases expression ISO Ellagic Acid results in increased expression of NNAT mRNA CTD PMID:12002526 NCBI chr 3:154,043,873...154,046,334
Ensembl chr 3:154,043,873...154,046,330
JBrowse link
G Nop56 NOP56 ribonucleoprotein decreases expression ISO Ellagic Acid results in decreased expression of NOP56 mRNA CTD PMID:12002526 NCBI chr 3:122,803,726...122,808,564
Ensembl chr 3:122,803,772...122,808,558
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of NOS2 protein] CTD PMID:28815802 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npas2 neuronal PAS domain protein 2 increases expression ISO Ellagic Acid results in increased expression of NPAS2 mRNA CTD PMID:12002526 NCBI chr 9:45,901,262...46,081,880
Ensembl chr 9:45,901,741...46,081,880
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of NQO1 mRNA; Ellagic Acid results in increased expression of NQO1 protein
[Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of NQO1 protein
CTD PMID:23546295 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Ellagic Acid results in increased activity of NR1I3 protein CTD PMID:21821919 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase decreases activity ISO Ellagic Acid results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr16:8,350,168...8,457,999
Ensembl chr16:8,350,326...8,457,996
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Ellagic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:25247703 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO [resveratrol co-treated with Ellagic Acid] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased expression of PCNA mRNA] CTD PMID:20103723 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 multiple interactions EXP Ellagic Acid inhibits the reaction [Rotenone results in increased nitrosation of and results in decreased activity of PDIA2 protein] CTD PMID:25247703
G Pgd phosphogluconate dehydrogenase decreases activity ISO Ellagic Acid results in decreased activity of PGD protein CTD PMID:25130191 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pla2g2a phospholipase A2 group IIA decreases expression ISO Ellagic Acid results in decreased expression of PLA2G2A mRNA CTD PMID:20816778 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Plp2 proteolipid protein 2 increases expression ISO Ellagic Acid results in increased expression of PLP2 mRNA CTD PMID:12002526 NCBI chr  X:15,679,254...15,682,653
Ensembl chr  X:15,679,254...15,682,652
JBrowse link
G Pml PML nuclear body scaffold decreases expression ISO Ellagic Acid results in decreased expression of PML mRNA CTD PMID:12002526 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression ISO Ellagic Acid results in decreased expression of PPARD mRNA CTD PMID:12002526 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO Ellagic Acid results in increased expression of PPARG protein CTD PMID:23811531 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions
decreases expression
ISO Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of PPARGC1A mRNA]
Ellagic Acid results in decreased expression of PPARGC1A mRNA
CTD PMID:30503583 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 decreases expression ISO Ellagic Acid results in decreased expression of PRKG1 mRNA CTD PMID:12002526 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Ptn pleiotrophin decreases expression
increases expression
ISO Ellagic Acid results in decreased expression of PTN mRNA
Ellagic Acid results in increased expression of PTN mRNA
CTD PMID:12002526 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Ptprn2 protein tyrosine phosphatase, receptor type N2 increases expression ISO Ellagic Acid results in increased expression of PTPRN2 mRNA CTD PMID:12002526 NCBI chr 6:144,384,773...145,133,042
Ensembl chr 6:144,384,773...145,133,042
JBrowse link
G Ran RAN, member RAS oncogene family decreases expression ISO Ellagic Acid results in decreased expression of RAN mRNA CTD PMID:12002526 NCBI chr12:31,319,556...31,324,105
Ensembl chr12:31,320,624...31,323,810
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions EXP Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RB1 protein] CTD PMID:27965107 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Reck reversion-inducing-cysteine-rich protein with kazal motifs increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of RECK mRNA; Ellagic Acid results in increased expression of RECK protein
zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK mRNA]; zinc chloride inhibits the reaction [Ellagic Acid results in increased expression of RECK protein]
CTD PMID:21573219 NCBI chr 5:59,348,568...59,415,169
Ensembl chr 5:59,348,639...59,415,135
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions
ISO
EXP
Ellagic Acid results in decreased expression of RELA mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of RELA protein]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of RELA protein]
CTD PMID:12002526 PMID:24877639 PMID:27965107 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rgs5 regulator of G-protein signaling 5 decreases expression ISO Ellagic Acid results in decreased expression of RGS5 mRNA CTD PMID:12002526 NCBI chr13:87,966,820...88,002,831
Ensembl chr13:87,966,758...88,003,035
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Ellagic Acid results in decreased expression of SCD mRNA CTD PMID:20816778 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Septin2 septin 2 increases expression ISO Ellagic Acid results in increased expression of SEPTIN2 mRNA CTD PMID:12002526 NCBI chr 9:100,624,876...100,658,053
Ensembl chr 9:100,624,876...100,658,050
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Ellagic Acid inhibits the reaction [sodium arsenite results in decreased expression of SOD2 mRNA] CTD PMID:29935397 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO Ellagic Acid results in decreased expression of SOD3 mRNA CTD PMID:12002526 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Star steroidogenic acute regulatory protein increases expression
multiple interactions
ISO Ellagic Acid results in increased expression of STAR mRNA
Ellagic Acid inhibits the reaction [sodium arsenate results in decreased expression of STAR mRNA]
CTD PMID:30503583 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression
decreases expression
ISO Ellagic Acid results in increased expression of STAT3 mRNA
Ellagic Acid results in decreased expression of STAT3 mRNA
CTD PMID:12002526 PMID:20816778 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C decreases expression ISO Ellagic Acid results in decreased expression of TAF1C mRNA CTD PMID:12002526 NCBI chr19:52,246,061...52,252,642
Ensembl chr19:52,246,068...52,252,587
JBrowse link
G Tcf12 transcription factor 12 increases expression ISO Ellagic Acid results in increased expression of TCF12 mRNA CTD PMID:12002526 NCBI chr 8:78,343,634...78,657,738
Ensembl chr 8:78,345,754...78,655,856
JBrowse link
G Tert telomerase reverse transcriptase multiple interactions
increases expression
ISO
EXP
Ellagic Acid inhibits the reaction [Estradiol results in increased expression of TERT mRNA alternative form]
Ellagic Acid inhibits the reaction [phosalone results in decreased activity of TERT protein]
Ellagic Acid results in increased expression of TERT mRNA alternative form
CTD PMID:19501078 PMID:27965107 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tfam transcription factor A, mitochondrial decreases expression ISO Ellagic Acid results in decreased expression of TFAM mRNA CTD PMID:12002526 NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
ISO
EXP
Ellagic Acid results in increased expression of TGFB1 mRNA
Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]
CTD PMID:12002526 PMID:24877639 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Glucose results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [sodium arsenate results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [sodium arsenite results in increased expression of TNF protein] CTD PMID:21762681 PMID:24877639 PMID:27965107 PMID:28815802 PMID:29455002 PMID:29854611 PMID:29864931 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP Ellagic Acid inhibits the reaction [Isoproterenol results in increased expression of TNNT2 protein] CTD PMID:21762681 NCBI chr13:52,662,974...52,680,992
Ensembl chr13:52,662,996...52,680,990
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
ISO
EXP
Ellagic Acid results in increased expression of TP53 protein
Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]; pifithrin inhibits the reaction [Ellagic Acid promotes the reaction [Quercetin results in increased phosphorylation of TP53 protein]]
Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 mRNA]; Ellagic Acid inhibits the reaction [phosalone results in increased expression of TP53 protein]
CTD PMID:15735102 PMID:23554011 PMID:27965107 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 decreases expression ISO Ellagic Acid results in decreased expression of UGP2 mRNA CTD PMID:12002526 NCBI chr14:106,208,174...106,249,322
Ensembl chr14:106,208,176...106,248,539
JBrowse link
G Usp4 ubiquitin specific peptidase 4 decreases expression ISO Ellagic Acid results in decreased expression of USP4 mRNA CTD PMID:12002526 NCBI chr 8:117,126,692...117,171,012
Ensembl chr 8:117,126,692...117,171,012
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO Ellagic Acid results in increased expression of WARS1 mRNA CTD PMID:12002526 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression ISO Ellagic Acid results in decreased expression of WEE1 protein CTD PMID:23554011 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression ISO Ellagic Acid results in decreased expression of ZBTB16 mRNA CTD PMID:12002526 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953
JBrowse link
G Zmym2 zinc finger MYM-type containing 2 increases expression ISO Ellagic Acid results in increased expression of ZMYM2 mRNA CTD PMID:12002526 NCBI chr15:37,156,250...37,229,803
Ensembl chr15:37,171,052...37,227,301
JBrowse link
formononetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
affects activity
ISO Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA]; formononetin inhibits the reaction [Epirubicin results in increased expression of ABCB1 mRNA]
formononetin affects the activity of ABCB1 protein
CTD PMID:15796199 PMID:23867903 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects activity
decreases expression
multiple interactions
ISO formononetin affects the activity of ABCC1 protein
formononetin results in decreased expression of ABCC1 mRNA
Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC1 mRNA]; formononetin inhibits the reaction [Epirubicin results in increased expression of ABCC1 mRNA]
CTD PMID:15796199 PMID:23867903 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases expression
ISO
EXP
Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mRNA]; formononetin inhibits the reaction [Epirubicin results in increased expression of ABCC2 mRNA]
formononetin promotes the reaction [Cisplatin results in increased expression of ABCC2 mRNA]
CTD PMID:23867903 PMID:28414026 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions EXP formononetin promotes the reaction [Cisplatin results in increased expression of ABCC4 mRNA] CTD PMID:28414026 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO fulvestrant promotes the reaction [formononetin results in increased activity of AHR protein] CTD PMID:28985473 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
formononetin promotes the reaction [Epirubicin results in increased expression of BAX mRNA]
formononetin inhibits the reaction [Cisplatin results in increased expression of BAX protein]
CTD PMID:23867903 PMID:28414026 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO
EXP
formononetin results in decreased expression of BCL2 mRNA
formononetin promotes the reaction [Cisplatin results in increased expression of BCL2 protein]
CTD PMID:23867903 PMID:28414026 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
ISO
EXP
Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP3 mRNA]; Epirubicin promotes the reaction [formononetin results in increased activity of CASP3 protein]; Epirubicin promotes the reaction [formononetin results in increased expression of CASP3 mRNA]; formononetin promotes the reaction [Epirubicin results in increased activity of CASP3 protein]; formononetin promotes the reaction [Epirubicin results in increased expression of CASP3 mRNA]
formononetin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]
CTD PMID:23867903 PMID:28414026 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
increases activity
ISO Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP8 mRNA]; Epirubicin promotes the reaction [formononetin results in increased activity of CASP8 protein]; Epirubicin promotes the reaction [formononetin results in increased expression of CASP8 mRNA] CTD PMID:23867903 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
increases activity
ISO Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP9 mRNA]; Epirubicin promotes the reaction [formononetin results in increased activity of CASP9 protein]; Epirubicin promotes the reaction [formononetin results in increased expression of CASP9 mRNA]; formononetin promotes the reaction [Epirubicin results in increased activity of CASP9 protein]; formononetin promotes the reaction [Epirubicin results in increased expression of CASP9 mRNA] CTD PMID:23867903 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Ccnb1 cyclin B1 increases expression
multiple interactions
ISO
EXP
formononetin results in increased expression of CCNB1 protein
XI-006 inhibits the reaction [formononetin results in increased expression of CCNB1 protein]
CTD PMID:28414026 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
EXP
ISO
formononetin results in increased expression of CCND1 protein
XI-006 inhibits the reaction [formononetin results in increased expression of CCND1 protein]
CTD PMID:28414026 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases hydroxylation
increases expression
multiple interactions
decreases methylation
ISO CYP1A1 protein results in increased hydroxylation of formononetin
formononetin results in increased expression of CYP1A1 mRNA
fulvestrant promotes the reaction [formononetin results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in decreased methylation of formononetin
CTD PMID:15479032 PMID:28985473 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO
EXP
formononetin results in decreased activity of CYP1A2 protein CTD PMID:26278343 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases methylation
increases expression
ISO CYP1B1 protein results in decreased methylation of formononetin
formononetin results in increased expression of CYP1B1 mRNA
CTD PMID:15479032 PMID:28985473 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO formononetin results in decreased activity of CYP2D6 protein CTD PMID:26278343 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Epo erythropoietin increases expression ISO formononetin results in increased expression of EPO mRNA CTD PMID:21309574 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Esr1 estrogen receptor 1 affects binding
multiple interactions
ISO formononetin binds to ESR1 protein
formononetin binds to and results in increased activity of ESR1 protein
CTD PMID:9751507 PMID:16076101 PMID:16773531 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
ISO formononetin binds to and results in increased activity of ESR2 protein
formononetin binds to ESR2 protein
CTD PMID:9751507 PMID:12224631 PMID:16076101 PMID:16773531 PMID:19913605 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP formononetin inhibits the reaction [Cisplatin results in increased expression of HAVCR1 mRNA] CTD PMID:28414026 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
ISO formononetin results in increased expression of HIF1A mRNA
formononetin results in increased expression of and results in decreased degradation of HIF1A protein
CTD PMID:21309574 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Il17a interleukin 17A multiple interactions ISO formononetin promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA] CTD PMID:25583575 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il4 interleukin 4 increases expression ISO formononetin results in increased expression of IL4 mRNA; formononetin results in increased expression of IL4 protein CTD PMID:16108819 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP formononetin results in increased expression of MDM2 protein CTD PMID:28414026 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mdm4 MDM4 regulator of p53 increases expression EXP formononetin results in increased expression of MDM4 protein CTD PMID:28414026 NCBI chr13:49,786,776...49,828,780
Ensembl chr13:49,792,794...49,828,720
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO formononetin inhibits the reaction [CXCL8 protein results in increased phosphorylation of NFKBIA protein] CTD PMID:22387535 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression
multiple interactions
EXP formononetin results in increased expression of NOS3 mRNA
formononetin results in increased phosphorylation of and results in increased activity of NOS3 protein
CTD PMID:19570671 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Slc22a2 solute carrier family 22 member 2 decreases expression EXP formononetin results in decreased expression of SLC22A2 mRNA CTD PMID:28414026 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression
EXP
ISO
formononetin inhibits the reaction [Cisplatin results in increased expression of TP53 protein]
formononetin results in decreased expression of TP53 protein
XI-006 inhibits the reaction [formononetin results in decreased expression of TP53 protein]
CTD PMID:28414026 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of formononetin CTD PMID:14557274 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of formononetin CTD PMID:14557274 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of formononetin CTD PMID:14557274 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
Goitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions
EXP goitrin results in increased expression of GSTA2 protein
Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTA2 protein]
CTD PMID:7532609 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression
increases expression
multiple interactions
EXP goitrin results in decreased expression of GSTP1 protein
goitrin results in increased expression of GSTP1 protein
Triiodothyronine inhibits the reaction [goitrin results in increased expression of GSTP1 protein]
CTD PMID:7532609 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
neobavaisoflavone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
EXP neobavaisoflavone inhibits the reaction [[CYP2E1 protein results in increased metabolism of 4-nitrophenol] which results in increased chemical synthesis of 4-nitrocatechol]
neobavaisoflavone results in decreased activity of CYP2E1 protein
CTD PMID:31870919 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression EXP neobavaisoflavone results in increased expression of CYP3A4 mRNA CTD PMID:31870919 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
pamidronate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases expression ISO pamidronate results in increased expression of ALPL protein CTD PMID:11683535 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G B2m beta-2 microglobulin decreases expression ISO pamidronate results in decreased expression of B2M protein CTD PMID:11683535 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO pamidronate results in decreased expression of BCL2 protein CTD PMID:10780527 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression ISO pamidronate results in increased expression of BGLAP protein CTD PMID:11683535 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bik BCL2-interacting killer increases response to substance ISO BIK protein results in increased susceptibility to pamidronate CTD PMID:16007125 NCBI chr 7:124,390,924...124,410,449
Ensembl chr 7:124,391,432...124,410,447
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO pamidronate results in increased cleavage of and results in increased activity of CASP3 protein
pamidronate results in increased cleavage of CASP3 protein
CTD PMID:15346059 PMID:16298452 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 increases cleavage ISO pamidronate results in increased cleavage of CASP9 protein CTD PMID:16298452 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO pamidronate results in decreased expression of COL1A1 mRNA; pamidronate results in decreased expression of COL1A1 protein CTD PMID:19597852 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Crp C-reactive protein decreases expression
increases expression
ISO pamidronate results in decreased expression of CRP protein
pamidronate results in increased expression of CRP protein
CTD PMID:9351880 PMID:11683535 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Fdps farnesyl diphosphate synthase decreases activity ISO
EXP
pamidronate results in decreased activity of FDPS protein CTD PMID:11160603 PMID:18325729 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fgf23 fibroblast growth factor 23 decreases expression ISO pamidronate results in decreased expression of FGF23 protein CTD PMID:15838626 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Pamidronate results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine] which results in increased secretion of IL18 protein CTD PMID:21282739 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions
ISO Pamidronate results in increased secretion of IL1B protein
[Pamidronate co-treated with Acetylmuramyl-Alanyl-Isoglutamine] results in increased secretion of IL1B protein; [Pamidronate co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein; geraniol inhibits the reaction [[Pamidronate co-treated with Acetylmuramyl-Alanyl-Isoglutamine] results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Pamidronate co-treated with lipopolysaccharide, E coli O55-B5] results in increased secretion of IL1B protein]; Pamidronate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]
CTD PMID:21282739 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 decreases expression
increases expression
ISO pamidronate results in decreased expression of IL6 protein
pamidronate results in increased expression of IL6 protein
CTD PMID:9351880 PMID:11683535 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases expression ISO pamidronate results in decreased expression of MAPK1 protein modified form CTD PMID:16298452 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
multiple interactions
ISO pamidronate results in increased cleavage of PARP1 protein
[pamidronate co-treated with ultra-high molecular weight polyethylene] results in increased cleavage of PARP1 protein
CTD PMID:10780527 PMID:12507583 PMID:15346059 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pon1 paraoxonase 1 decreases activity
multiple interactions
EXP pamidronate results in decreased activity of PON1 protein
[pamidronate results in decreased activity of PON1 protein] which results in decreased metabolism of homocysteine thiolactone; [pamidronate results in decreased activity of PON1 protein] which results in decreased metabolism of Paraoxon; [pamidronate results in decreased activity of PON1 protein] which results in decreased metabolism of phenyl acetate
CTD PMID:27387541 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family decreases prenylation ISO pamidronate results in decreased prenylation of RAP1A protein CTD PMID:11595616 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO pamidronate results in decreased expression of RHOA protein modified form CTD PMID:16298452 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 decreases expression ISO pamidronate results in decreased expression of ROCK1 protein CTD PMID:16298452 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO pamidronate results in increased expression of TNF protein
pamidronate inhibits the reaction [ultra-high molecular weight polyethylene results in increased secretion of TNF protein]
CTD PMID:9351880 PMID:12507583 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions
increases expression
ISO pamidronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B mRNA]; pamidronate inhibits the reaction [Dexamethasone results in decreased expression of TNFRSF11B protein]
pamidronate results in increased expression of TNFRSF11B mRNA; pamidronate results in increased expression of TNFRSF11B protein
CTD PMID:11855844 NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
JBrowse link
pyridoxal 5'-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpl alkaline phosphatase, biomineralization associated increases abundance ISO ALPL gene mutant form results in increased abundance of Pyridoxal Phosphate CTD PMID:7550313 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP Pyridoxal Phosphate results in decreased expression of BCL2 protein CTD PMID:16690808 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Pyridoxal Phosphate inhibits the reaction [Acetaldehyde results in increased expression of FN1 mRNA] CTD PMID:8151099 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fut8 fucosyltransferase 8 multiple interactions
decreases activity
ISO Fucose analog inhibits the reaction [Pyridoxal Phosphate results in decreased activity of FUT8 protein] CTD PMID:12770769 NCBI chr 6:100,305,957...100,537,208
Ensembl chr 6:100,337,226...100,537,224
JBrowse link
G Gad1 glutamate decarboxylase 1 affects binding
decreases activity
increases activity
ISO
EXP
Pyridoxal Phosphate binds to GAD1 protein modified form
Pyridoxal Phosphate results in decreased activity of GAD1 protein
Pyridoxal Phosphate results in increased activity of GAD1 protein
CTD PMID:171340 PMID:7463050 PMID:15686475 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 affects binding ISO Pyridoxal Phosphate binds to GAD2 protein; Pyridoxal Phosphate binds to GAD2 protein modified form CTD PMID:15686475 PMID:15690345 PMID:15836621 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Gh1 growth hormone 1 decreases secretion EXP Pyridoxal Phosphate results in decreased secretion of GH1 protein CTD PMID:16690808 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Nrip1 nuclear receptor interacting protein 1 multiple interactions ISO Pyridoxal Phosphate binds to and results in increased activity of NRIP1 protein CTD PMID:17277785 NCBI chr11:14,658,225...14,742,478
Ensembl chr11:14,658,225...14,741,563
JBrowse link
G Pomc proopiomelanocortin decreases secretion ISO Pyridoxal Phosphate results in decreased secretion of POMC protein CTD PMID:16690808 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP Pyridoxal Phosphate inhibits the reaction [Ethanol results in decreased activity of PPARA protein] CTD PMID:11022051 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Prl prolactin decreases secretion EXP Pyridoxal Phosphate results in decreased secretion of PRL protein CTD PMID:16690808 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G RGD1566085 similar to pyridoxal (pyridoxine, vitamin B6) kinase decreases activity EXP Pyridoxal Phosphate results in decreased activity of PDXK protein CTD PMID:7463050 NCBI chr20:10,883,952...10,912,870
Ensembl chr20:10,889,573...10,912,769
JBrowse link
sodium aurothiomalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ACKR3 mRNA CTD PMID:19192274 NCBI chr 9:97,355,881...97,367,455
Ensembl chr 9:97,355,924...97,367,445
JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ADORA2A mRNA CTD PMID:19192274 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of AMIGO2 mRNA CTD PMID:19192274 NCBI chr 7:138,704,124...138,707,221
Ensembl chr 7:138,704,126...138,707,221
JBrowse link
G Antxr1 ANTXR cell adhesion molecule 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of ANTXR1 mRNA CTD PMID:19192274 NCBI chr 4:118,946,267...119,131,202
Ensembl chr 4:118,946,268...119,131,202
JBrowse link
G Aox1 aldehyde oxidase 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of AOX1 mRNA CTD PMID:19192274 NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of BCL2A1 mRNA CTD PMID:19192274 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of BST2 mRNA CTD PMID:19192274 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CCL20 mRNA; Gold Sodium Thiomalate results in decreased expression of CCL20 protein CTD PMID:19192274 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of CCN1 mRNA CTD PMID:19192274 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn5 cellular communication network factor 5 increases expression ISO Gold Sodium Thiomalate results in increased expression of CCN5 mRNA CTD PMID:19192274 NCBI chr 3:160,207,969...160,219,316
Ensembl chr 3:160,207,913...160,219,331
JBrowse link
G Cd28 Cd28 molecule multiple interactions
affects response to substance
ISO CD28 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
CD28 protein affects the susceptibility to Gold Sodium Thiomalate
CTD PMID:19077085 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:10820281 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Clgn calmegin decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CLGN mRNA CTD PMID:19192274 NCBI chr19:24,545,257...24,578,527
Ensembl chr19:24,545,318...24,576,798
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Gold Sodium Thiomalate results in increased expression of COL1A1 mRNA CTD PMID:19192274 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Colec12 collectin sub-family member 12 increases expression ISO Gold Sodium Thiomalate results in increased expression of COLEC12 mRNA CTD PMID:19192274 NCBI chr18:867,048...1,054,047
Ensembl chr18:867,048...1,052,606
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCL1 mRNA CTD PMID:19192274 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCL2 mRNA CTD PMID:19192274 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCL1 mRNA CTD PMID:19192274 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of CXCR4 mRNA CTD PMID:19192274 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Ddx10 DEAD-box helicase 10 increases expression ISO Gold Sodium Thiomalate results in increased expression of DDX10 mRNA CTD PMID:19192274 NCBI chr 8:57,667,472...57,830,504
Ensembl chr 8:57,667,472...57,830,504
JBrowse link
G Ddx58 DEXD/H-box helicase 58 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of DDX58 mRNA CTD PMID:19192274 NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of EFEMP1 mRNA CTD PMID:19192274 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases expression ISO Gold Sodium Thiomalate results in increased expression of ENPP2 mRNA CTD PMID:19192274 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 increases expression ISO Gold Sodium Thiomalate results in increased expression of ENTPD3 mRNA CTD PMID:19192274 NCBI chr 8:129,201,000...129,232,436
Ensembl chr 8:129,201,669...129,232,677
JBrowse link
G Fbl fibrillarin affects localization
decreases activity
multiple interactions
ISO Gold Sodium Thiomalate affects the localization of FBL protein
Gold Sodium Thiomalate results in decreased activity of FBL protein
CD28 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IFNG protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IL4 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]; IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
CTD PMID:10942594 PMID:19077085 NCBI chr 1:85,103,519...85,112,619
Ensembl chr 1:85,103,519...85,112,619
JBrowse link
G Fbln1 fibulin 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of FBLN1 mRNA CTD PMID:19192274 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468
JBrowse link
G Fgf7 fibroblast growth factor 7 increases expression ISO Gold Sodium Thiomalate results in increased expression of FGF7 mRNA CTD PMID:19192274 NCBI chr 3:118,315,859...118,368,464
Ensembl chr 3:118,317,761...118,366,872
JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of GBP1 mRNA CTD PMID:19192274 NCBI chr 2:248,343,334...248,423,402
Ensembl chr 2:248,398,917...248,409,570
JBrowse link
G Gpm6b glycoprotein m6b increases expression ISO Gold Sodium Thiomalate results in increased expression of GPM6B mRNA CTD PMID:19192274 NCBI chr  X:29,604,607...29,751,174
Ensembl chr  X:29,607,075...29,648,403
JBrowse link
G Gsdme gasdermin E decreases expression ISO Gold Sodium Thiomalate results in decreased expression of GSDME mRNA CTD PMID:19192274 NCBI chr 4:79,934,075...79,999,678
Ensembl chr 4:79,934,887...79,989,572
JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of HERC6 mRNA CTD PMID:19192274 NCBI chr 4:88,606,851...88,649,424
Ensembl chr 4:88,607,518...88,649,216
JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Gold Sodium Thiomalate results in decreased expression of HILPDA mRNA CTD PMID:19192274 NCBI chr 4:56,547,600...56,550,584
Ensembl chr 4:56,549,739...56,549,993
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI27 mRNA CTD PMID:19192274 NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
JBrowse link
G Ifi35 interferon-induced protein 35 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI35 mRNA CTD PMID:19192274 NCBI chr10:89,358,376...89,366,628
Ensembl chr10:89,358,376...89,366,626
JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI44 mRNA CTD PMID:19192274 NCBI chr 2:256,897,765...256,915,591
Ensembl chr 2:256,897,772...256,915,569
JBrowse link
G Ifi44l interferon-induced protein 44-like decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFI44L mRNA CTD PMID:19192274 NCBI chr 2:256,948,722...256,979,573
Ensembl chr 2:256,964,860...256,978,668
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFIH1 mRNA CTD PMID:19192274 NCBI chr 3:48,557,696...48,604,097
Ensembl chr 3:48,557,696...48,604,097
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IFIT3 mRNA CTD PMID:19192274 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382
JBrowse link
G Ifng interferon gamma multiple interactions
affects response to substance
ISO IFNG protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
IFNG protein affects the susceptibility to Gold Sodium Thiomalate
CTD PMID:19077085 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [Lipopolysaccharides results in increased activity of IKBKB protein] CTD PMID:10820281 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Gold Sodium Thiomalate co-treated with mercury nitrate analog] results in increased expression of IL10 protein CTD PMID:11824965 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [[IL1B protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; Gold Sodium Thiomalate inhibits the reaction [IL1B protein results in increased expression of PTGES] CTD PMID:16393772 PMID:25314295 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rn interleukin 1 receptor antagonist decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IL1RN mRNA CTD PMID:19192274 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il23a interleukin 23 subunit alpha decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IL23A mRNA CTD PMID:19192274 NCBI chr 7:2,710,609...2,712,723
Ensembl chr 7:2,710,609...2,712,723
JBrowse link
G Il4 interleukin 4 multiple interactions
affects response to substance
ISO IL4 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
IL4 protein affects the susceptibility to Gold Sodium Thiomalate
CTD PMID:19077085 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
affects response to substance
ISO [Gold Sodium Thiomalate co-treated with mercury nitrate analog] results in increased expression of IL6 protein
Gold Sodium Thiomalate results in decreased expression of IL6 mRNA; Gold Sodium Thiomalate results in decreased expression of IL6 protein
IL6 protein affects the susceptibility to Gold Sodium Thiomalate
IL6 protein affects the reaction [Gold Sodium Thiomalate results in decreased activity of FBL protein]
CTD PMID:11824965 PMID:19077085 PMID:19192274 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irf7 interferon regulatory factor 7 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of IRF7 mRNA CTD PMID:19192274 NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ISG15 mRNA CTD PMID:19192274 NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of ISG20 mRNA CTD PMID:19192274 NCBI chr 1:140,602,553...140,608,892
Ensembl chr 1:140,601,791...140,608,946
JBrowse link
G Lamb3 laminin subunit beta 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of LAMB3 mRNA CTD PMID:19192274 NCBI chr13:112,031,614...112,073,187
Ensembl chr13:112,031,594...112,073,186
JBrowse link
G Lxn latexin increases expression ISO Gold Sodium Thiomalate results in increased expression of LXN mRNA CTD PMID:19192274 NCBI chr 2:164,628,565...164,634,434
Ensembl chr 2:164,628,566...164,634,434
JBrowse link
G Ly6e lymphocyte antigen 6 family member E decreases expression ISO Gold Sodium Thiomalate results in decreased expression of LY6E mRNA CTD PMID:19192274 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MARCKS mRNA CTD PMID:19192274 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MET mRNA CTD PMID:19192274 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MMP10 mRNA CTD PMID:19192274 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of MX1 mRNA CTD PMID:19192274 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Ndufa4l2 NDUFA4, mitochondrial complex associated like 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of NDUFA4L2 mRNA CTD PMID:19192274 NCBI chr 7:70,821,904...70,824,085
Ensembl chr 7:70,821,957...70,824,085
JBrowse link
G Nmb neuromedin B decreases expression ISO Gold Sodium Thiomalate results in decreased expression of NMB mRNA CTD PMID:19192274 NCBI chr 1:142,721,263...142,724,646
Ensembl chr 1:142,721,002...142,724,511
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [[IL1B protein results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide] CTD PMID:16393772 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of NR4A3 mRNA CTD PMID:19192274 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A decreases expression ISO Gold Sodium Thiomalate results in decreased expression of OAS1 mRNA CTD PMID:19192274 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like decreases expression ISO Gold Sodium Thiomalate results in decreased expression of OASL mRNA CTD PMID:19192274 NCBI chr12:47,444,138...47,456,680
Ensembl chr12:47,444,104...47,456,894
JBrowse link
G Olfml2b olfactomedin-like 2B increases expression ISO Gold Sodium Thiomalate results in increased expression of OLFML2B mRNA CTD PMID:19192274 NCBI chr13:88,995,301...89,032,487
Ensembl chr13:88,995,316...89,032,487
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Gold Sodium Thiomalate results in decreased expression of PHGDH mRNA CTD PMID:19192274 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Plpp3 phospholipid phosphatase 3 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of PLPP3 mRNA CTD PMID:19192274 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 increases expression ISO Gold Sodium Thiomalate results in increased expression of PPP4R2 mRNA CTD PMID:19192274 NCBI chr 4:133,285,552...133,323,755
Ensembl chr 4:133,285,552...133,323,755
JBrowse link
G Ptges prostaglandin E synthase multiple interactions ISO Gold Sodium Thiomalate inhibits the reaction [IL1B protein results in increased expression of PTGES] CTD PMID:25314295 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of PTGS2 mRNA CTD PMID:19192274 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of RARRES1 mRNA CTD PMID:19192274 NCBI chr 2:164,650,722...164,684,982
Ensembl chr 2:164,650,722...164,684,985
JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RGS4 mRNA CTD PMID:19192274 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RIPK2 mRNA CTD PMID:19192274 NCBI chr 5:29,838,713...29,870,390
Ensembl chr 5:29,838,747...29,870,735
JBrowse link
G Rnf19b ring finger protein 19B decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RNF19B mRNA CTD PMID:19192274 NCBI chr 5:147,246,032...147,270,892
Ensembl chr 5:147,246,037...147,270,957
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of RSAD2 mRNA CTD PMID:19192274 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of SLC7A11 mRNA CTD PMID:19192274 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Sms spermine synthase decreases expression ISO Gold Sodium Thiomalate results in decreased expression of SMS mRNA CTD PMID:19192274 NCBI chr  X:40,363,646...40,415,110
Ensembl chr  X:40,363,646...40,415,109
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of SOD2 mRNA CTD PMID:19192274 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spon1 spondin 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of SPON1 mRNA CTD PMID:19192274 NCBI chr 1:178,568,777...178,935,715
Ensembl chr 1:178,636,544...178,935,051
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of STAT1 mRNA CTD PMID:19192274 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Sts steroid sulfatase increases expression ISO Gold Sodium Thiomalate results in increased expression of STS mRNA CTD PMID:19192274 NCBI chr  X:45,420,418...45,428,748
Ensembl chr  X:45,420,596...45,428,750
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Gold Sodium Thiomalate results in increased expression of THBS1 mRNA CTD PMID:19192274 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thbs2 thrombospondin 2 increases expression ISO Gold Sodium Thiomalate results in increased expression of THBS2 mRNA CTD PMID:19192274 NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
JBrowse link
G Tlr2 toll-like receptor 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of TLR2 mRNA CTD PMID:19192274 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 decreases expression ISO Gold Sodium Thiomalate results in decreased expression of TNFAIP2 mRNA CTD PMID:19192274 NCBI chr 6:135,890,869...135,903,647
Ensembl chr 6:135,890,931...135,903,647
JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO Gold Sodium Thiomalate results in increased expression of TXNIP mRNA CTD PMID:19192274 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions
decreases activity
ISO
EXP
Gold Sodium Thiomalate inhibits the reaction [TXNRD1 protein affects the metabolism of Dithionitrobenzoic Acid]
Gold Sodium Thiomalate results in decreased activity of TXNRD1 protein
CTD PMID:16510263 PMID:17229725 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Txnrd2 thioredoxin reductase 2 decreases activity EXP Gold Sodium Thiomalate results in decreased activity of TXNRD2 protein CTD PMID:15458826 NCBI chr11:86,667,994...86,716,063
Ensembl chr11:86,667,997...86,716,254
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19875
    role 19825
      biological role 19825
        biochemical role 19360
          enzyme inhibitor 18230
            EC 2.* (transferase) inhibitor 13857
              EC 2.7.* (P-containing group transferase) inhibitor 13528
                EC 2.7.7.* (nucleotidyltransferase) inhibitor 1004
                  DNA polymerase inhibitor 693
                    EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor 462
                      aphidicolin 21
                      daidzein + 243
                      daidzein(1-) 0
                      ellagic acid + 123
                      neobavaisoflavone + 2
                      phosphonoacetic acid + 22
                      pyridoxal 5'-phosphate + 18
                      sodium aurothiomalate 87
                      solanapyrone A + 2
paths to the root