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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Mycoplasma genitalium metabolite
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Accession:CHEBI:131604 term browser browse the term
Definition:Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium.
Synonyms:related_synonym: Mycoplasma genitalium metabolites


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amlodipine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G REN renin increases expression EXP Amlodipine results in increased expression of REN protein CTD PMID:10218729 NCBI chr38:744,540...766,998
Ensembl chr38:744,614...755,012
JBrowse link
eplerenone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AR androgen receptor multiple interactions EXP Eplerenone binds to and results in decreased activity of AR protein CTD PMID:23242577 NCBI chr24:34,713,390...34,731,461
NCBI chr  X:51,969,785...52,167,450
Ensembl chr  X:51,969,785...52,151,912
JBrowse link
felodipine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1I2 nuclear receptor subfamily 1 group I member 2 increases activity EXP Felodipine results in increased activity of NR1I2 protein CTD PMID:27732639 NCBI chr33:23,444,367...23,456,405
Ensembl chr33:23,432,690...23,455,347
JBrowse link
simvastatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS3 nitric oxide synthase 3 increases expression
decreases expression
EXP Simvastatin results in increased expression of NOS3 protein
Simvastatin results in decreased expression of NOS3 mRNA
CTD PMID:11087217 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277
JBrowse link
thapsigargin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17416481 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257
JBrowse link
vincristine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 increases export
multiple interactions
affects response to substance
EXP ABCB1 protein results in increased export of Vincristine
valspodar inhibits the reaction [ABCB1 protein affects the susceptibility to Vincristine]
CTD PMID:24975508 PMID:28093773 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727
JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 decreases response to substance EXP ABCC1 protein results in decreased susceptibility to Vincristine CTD PMID:12516967 NCBI chr 6:27,855,702...27,950,140
Ensembl chr 6:27,855,702...27,989,331
JBrowse link
yohimbine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma multiple interactions EXP Yohimbine inhibits the reaction [[Clonidine results in increased activity of PIK3CG protein] which results in increased chemical synthesis of phosphatidylinositol 3-phosphate]; Yohimbine inhibits the reaction [Clonidine results in increased activity of PIK3CG protein] CTD PMID:15958164 NCBI chr18:13,576,966...13,611,748
Ensembl chr18:13,570,999...13,611,141
JBrowse link
G PRKCZ protein kinase C zeta multiple interactions EXP Yohimbine inhibits the reaction [Clonidine results in increased phosphorylation of PRKCZ protein] CTD PMID:15958164 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664
JBrowse link

Term paths to the root
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  CHEBI ontology 226
    role 226
      biological role 226
        biochemical role 187
          metabolite 180
            prokaryotic metabolite 129
              bacterial metabolite 129
                Mycoplasma genitalium metabolite 9
                  1,2-di-[(11Z)-octadecenoyl]glycerol 0
                  1,2-di-[(9Z)-hexadecenoyl]glycerol 0
                  1,2-dibutyrin 0
                  1,2-didodecanoyl-sn-glycero-3-cytidine 5'-diphosphate 0
                  1,2-dihexadec-9-enoyl-sn-glycero-3-cytidine 5'-diphosphate 0
                  1,2-dioctadec-11-enoyl-sn-glycero-3-cytidine 5'-diphosphate 0
                  1,2-dioctadecanoyl-sn-glycero-3-cytidine 5'-diphosphate 0
                  1,2-ditetradec-7-enoyl-sn-glycero-3-cytidine 5'-diphosphate 0
                  1,2-ditetradecanoyl-sn-glycero-3-cytidine 5'-diphosphate 0
                  1,3'-bis(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-5-amino-5-methyl-6-\{2-oxo-1,3-diazabicyclo[2.2.0]hex-4-en-6-yl\}-1,3-diazinane-2,4-dione 0
                  1,3'-bis(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-6-(5,6-diamino-2-oxo-2,3,4,5-tetrahydropyrimidin-4-yl)-1,3-diazabicyclo[2.2.0]hex-4-en-2-one 0
                  1,3'-bis(2-deoxy-beta-D-erythro-pentofuranosyl)-5-amino-5-methyl-6-\{2-oxo-1,3-diazabicyclo[2.2.0]hex-4-en-6-yl\}-1,3-diazinane-2,4-dione 0
                  1,3'-bis(2-deoxy-beta-D-erythro-pentofuranosyl)-6-(5,6-diamino-2-oxo-2,3,4,5-tetrahydropyrimidin-4-yl)-1,3-diazabicyclo[2.2.0]hex-4-en-2-one 0
                  1-myristoyl-2-oleoylglycerol + 0
                  2',3'-cyclic CMP 0
                  2'-deoxy-5,6-dihydroxy-5,6-dihydrocytidine 0
                  2'-deoxy-5,6-dihydroxy-5,6-dihydrocytidine 5'-monophosphate 0
                  2'-deoxy-5-(4,5-dihydroxypentyl)uridine 0
                  2'-deoxy-5-(4,5-dihydroxypentyl)uridine 5'-monophosphate 0
                  2'-deoxycytidine 5'-monophosphate dimer 0
                  2'-deoxycytidine dimer 0
                  2'-deoxycytidine-thymidine dimer 0
                  2'-deoxyinosine-5'-monophosphate 0
                  2,3-dideoxy-beta-D-ribose 5-phosphate 0
                  2,3-dipalmitoyl-S-glycerylcysteine 0
                  2-deoxy-D-glucose 6-phosphate 0
                  2-phenylpropan-2-ol 0
                  3'-(N-formyl-L-methionyl)-AMP 0
                  3'-L-alanyl-AMP 0
                  3'-L-arginyl-AMP 0
                  3'-L-asparaginyl-AMP 0
                  3'-L-aspartyl-AMP 0
                  3'-L-cysteinyl-AMP 0
                  3'-L-glutaminyl-AMP 0
                  3'-L-glutamyl-AMP 0
                  3'-L-histidyl-AMP 0
                  3'-L-isoleucyl-AMP 0
                  3'-L-leucyl-AMP 0
                  3'-L-lysyl-AMP 0
                  3'-L-methionyl-AMP 0
                  3'-L-phenylalanyl-AMP 0
                  3'-L-prolyl-AMP 0
                  3'-L-seryl-AMP 0
                  3'-L-threonyl-AMP 0
                  3'-L-tryptophyl-AMP 0
                  3'-L-tyrosyl-AMP 0
                  3'-L-valyl-AMP 0
                  3'-glycyl-AMP 0
                  4,5-diamino-1,2,4a,4b,7,8,8a,8b-octahydro-1,3,6,8-tetraazabiphenylene-2,7-dione 0
                  4-(5,6-diamino-2-oxo-2,3,4,5-tetrahydropyrimidin-4-yl)-1,2-dihydropyrimidin-2-one 0
                  4-amino-5-hydroxy-6-(5-methyl-2-oxo-1,2,3,4-tetrahydropyrimidin-4-yl)-2,5-dihydropyrimidin-2-one 0
                  4a,4b-dimethylhexahydro-1,3,6,8-tetraazabiphenylene-2,4,5,7-tetrone 0
                  5',6'-diamino-1,3'-bis(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-4',5'-dihydro[4,4'-bipyrimidine]-2,2'(1H,3'H)-dione 0
                  5',6'-diamino-1,3'-bis(2-deoxy-beta-D-erythro-pentofuranosyl)-4',5'-dihydro[4,4'-bipyrimidine]-2,2'(1H,3'H)-dione 0
                  5'-d(pGpG)-3' + 0
                  5,6-dihydrothymidine 0
                  5,6-dihydrothymidine 5'-monophosphate 0
                  5,6-dihydroxy-2'-deoxyuridine 0
                  5,6-dihydroxy-2'-deoxyuridine 5'-monophosphate 0
                  5,6-dihydroxyuracil 0
                  5-(4,5-dihydroxypentyl)uracil 0
                  5-O-phosphono-2-deoxyribosyl-(3->5)-2,3-dideoxyribose 0
                  5-O-phosphono-2-deoxyribosyl-(3->5)-2-deoxyribose 0
                  5-amino-4a-methyl-1,2,3,4,4a,4b,7,8,8a,8b-decahydro-1,3,6,8-tetraazabiphenylene-2,4,7-trione 0
                  5-amino-5-methyl-6-\{2-oxo-1,3-diazabicyclo[2.2.0]hex-4-en-6-yl\}-1,3-diazinane-2,4-dione 0
                  5-carboxy-2'-deoxyuridine 0
                  5-carboxy-2'-deoxyuridine 5'-monophosphate 0
                  5-carboxymethylaminomethyl-2-thiouridine 0
                  5-carboxymethylaminomethyl-2-thiouridine 5'-monophosphate 0
                  6'-amino-1,3'-bis(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-5'-hydroxy-5-methyl-3,4-dihydro[4,4'-bipyrimidine]-2,2'(1H,3'H)-dione 0
                  6'-amino-1,3'-bis(2-deoxy-beta-D-erythro-pentofuranosyl)-5'-hydroxy-5-methyl-3,4-dihydro[4,4'-bipyrimidine]-2,2'(1H,3'H)-dione 0
                  6-(5,6-diamino-2-oxo-2,3,4,5-tetrahydropyrimidin-4-yl)-1,3-diazabicyclo[2.2.0]hex-4-en-2-one 0
                  6-azathymidine 0
                  6-azathymidine 5'-monophosphate 0
                  6-azathymine + 0
                  8,5'-cyclo-2'-deoxyadenosine 0
                  8,5'-cyclo-2'-deoxyadenosine monophosphate 0
                  8,5'-cyclo-2'-deoxyguanosine 0
                  8,5'-cyclo-2'-deoxyguanosine monophosphate 0
                  8-aza-2'-deoxyadenosine 5'-monophosphate 0
                  8-azaadenine + 0
                  Arg-Arg 0
                  Asn-Asn 0
                  Asp-Asp 0
                  CDP-dipalmitoyl-sn-glycerol 0
                  Cys-Cys 0
                  Gln-Gln 0
                  Glu-Glu + 0
                  His-His 0
                  Ile-Ile 0
                  L-alanyl-L-alanine 0
                  Leu-Leu 0
                  Lys-Lys 0
                  Met-Met + 0
                  N(6)-(5'-adenylyl)-L-lysine 0
                  N(6)-carbamoylmethyl-2'-deoxyadenosine 0
                  N(6)-carbamoylmethyl-2'-deoxyadenosine 5'-monophosphate 0
                  N(6)-carbamoylmethyladenine 0
                  N-(5'-adenylyl)morpholine 0
                  N-formyl-L-methionyl-L-methionine 0
                  N-hexadecanoylsphingosine 0
                  Phe-Phe 0
                  Pro-Pro 0
                  S-adenosyl-L-methionine + 0
                  Ser-Ser 0
                  Thr-Thr 0
                  Trp-Trp 0
                  Tyr-Tyr 0
                  Val-Val 0
                  adenosine 5'-phosphoramidate 0
                  butyric acid + 2
                  chloramphenicol + 0
                  cumene hydroperoxide 0
                  cyclic di-AMP 0
                  dAp-dAp 0
                  dCDP 0
                  dCMP-dTMP 0
                  difloxacin 0
                  dpC-dpC 0
                  menaquinone-7 0
                  methanol + 7
                  pApA 0
                  pCpC 0
                  pristinamycin IIA + 0
                  tetrahexadec-9-enoyl cardiolipin 0
                  tetrahexadecanoyl cardiolipin 0
                  tetraoctadec-11-enoyl cardiolipin 0
                  thymidine 5'-monophosphate dimer 0
                  thymidine dimer 0
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