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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:C18-steroid
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Accession:CHEBI:131591 term browser browse the term
Definition:A steroid compound with a structure based on a 18-carbon (estrane) skeleton.
Synonyms:related_synonym: C18-steroids



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trenbolone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein multiple interactions
affects expression
increases expression
EXP Dihydrotestosterone promotes the reaction [Trenbolone Acetate analog results in increased expression of APP protein modified form]; Flutamide inhibits the reaction [Trenbolone Acetate analog results in increased expression of APP protein modified form]; fulvestrant inhibits the reaction [Trenbolone Acetate analog results in increased expression of APP protein modified form]; trilostane inhibits the reaction [Dihydrotestosterone promotes the reaction [Trenbolone Acetate analog results in increased expression of APP protein modified form]]
Trenbolone Acetate analog affects the expression of APP protein modified form
CTD PMID:25461682 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ar androgen receptor multiple interactions
affects binding
increases activity
ISO
EXP
Trenbolone Acetate binds to and results in increased activity of AR protein; Trenbolone Acetate inhibits the reaction [Metribolone results in increased activity of AR protein]; triclocarban promotes the reaction [Trenbolone Acetate results in increased activity of AR protein]
Trenbolone Acetate binds to AR protein
CTD PMID:14565775 PMID:16818248 PMID:18324785 PMID:20371976 PMID:20821581 More... NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
EXP Dihydrotestosterone promotes the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]; Flutamide promotes the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]; fulvestrant affects the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]; Testosterone promotes the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]; trilostane inhibits the reaction [Dihydrotestosterone promotes the reaction [Trenbolone Acetate analog results in increased activity of CASP3 protein]] CTD PMID:25461682 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Trenbolone Acetate binds to and results in increased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Trenbolone Acetate binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression EXP Trenbolone Acetate results in increased expression of ODC1 mRNA CTD PMID:17688994 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Psen1 presenilin 1 multiple interactions
decreases expression
EXP Flutamide inhibits the reaction [Trenbolone Acetate analog results in decreased expression of PSEN1 protein]; fulvestrant inhibits the reaction [Trenbolone Acetate analog results in decreased expression of PSEN1 protein]; Testosterone affects the reaction [Trenbolone Acetate analog results in decreased expression of PSEN1 protein]; Trenbolone Acetate analog inhibits the reaction [Dihydrotestosterone results in increased expression of PSEN1 protein]; trilostane inhibits the reaction [Trenbolone Acetate analog inhibits the reaction [Dihydrotestosterone results in increased expression of PSEN1 protein]] CTD PMID:25461682 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO Trenbolone Acetate binds to and results in increased activity of THRB protein CTD PMID:33049310 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    chemical entity 20071
      atom 20071
        nonmetal atom 19963
          carbon atom 19896
            organic molecular entity 19896
              lipid 17772
                steroid 14393
                  C18-steroid 8
                    17beta-hydroxy-5alpha-estr-1(10)-en-3-one 0
                    trenbolone 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19974
                    p-block element atom 19974
                      carbon group element atom 19903
                        carbon atom 19896
                          organic molecular entity 19896
                            organic molecule 19844
                              organic cyclic compound 19605
                                organic polycyclic compound 17197
                                  steroid 14393
                                    steroid fundamental parent 14156
                                      estrane 11899
                                        C18-steroid 8
                                          17beta-hydroxy-5alpha-estr-1(10)-en-3-one 0
                                          trenbolone 8
paths to the root