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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hyaluronic acid synthesis inhibitor
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Accession:CHEBI:131561 term browser browse the term
Definition:Any compound that inhibits one or more steps in the pathway leading to the synthesis of hyaluronic acid.
Synonyms:related_synonym: HA inhibitor;   HA inhibitors;   HA synthesis inhibitor;   HA synthesis inhibitors;   hyaluronic acid inhibitor;   hyaluronic acid inhibitors;   hyaluronic acid synthesis inhibitors



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4-methylumbelliferone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD44 CD44 molecule decreases expression EXP Hymecromone results in decreased expression of CD44 mRNA CTD PMID:23139787 NCBI chr 2:25,788,699...25,884,209
Ensembl chr 2:25,788,704...25,884,153
JBrowse link
G FBN1 fibrillin 1 decreases expression EXP Hymecromone results in decreased expression of FBN1 mRNA CTD PMID:23139787 NCBI chr 1:123,102,011...123,359,649
Ensembl chr 1:123,102,009...123,359,649
JBrowse link
G FN1 fibronectin 1 decreases expression EXP Hymecromone results in decreased expression of FN1 mRNA; Hymecromone results in decreased expression of FN1 protein CTD PMID:23139787 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,014
JBrowse link
G TNC tenascin C decreases expression EXP Hymecromone results in decreased expression of TNC mRNA CTD PMID:23139787 NCBI chr 1:255,533,235...255,630,381
Ensembl chr 1:255,532,449...255,630,377
JBrowse link
G VCAN versican decreases expression EXP Hymecromone results in decreased expression of VCAN mRNA; Hymecromone results in decreased expression of VCAN protein CTD PMID:23139787 NCBI chr 2:91,682,177...91,811,674
Ensembl chr 2:91,358,399...91,811,208
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 918
    role 871
      biological role 871
        inhibitor 543
          hyaluronic acid synthesis inhibitor 5
            4-methylumbelliferone + 5
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