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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid
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Accession:CHEBI:131502 term browser browse the term
Definition:A imidazolidine-2,4-dione that is 7-(2,5-dioxoimidazolidin-4-yl)heptanoic acid in which the imidazoline ring as substituted at position 3 by a 3-(3-cyclohexyl-3-hydroxypropyl) group.
Synonyms:related_synonym: 3-(3-Cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidine-4-heptanoic acid;   Formula=C19H32N2O5;   InChI=1S/C19H32N2O5/c22-16(14-8-4-3-5-9-14)12-13-21-15(18(25)20-19(21)26)10-6-1-2-7-11-17(23)24/h14-16,22H,1-13H2,(H,23,24)(H,20,25,26);   InChIKey=ZIDQIOZJEJFMOH-UHFFFAOYSA-N;   SMILES=C(CN1C(NC(C1CCCCCCC(O)=O)=O)=O)C(C2CCCCC2)O
 xref: CAS:75693-75-3
 xref_mesh: MESH:C030669
 xref: Reaxys:964618



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7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptgdr prostaglandin D2 receptor multiple interactions ISO
EXP
BW 245C binds to and results in increased activity of PTGDR protein; BW 245C inhibits the reaction [Prostaglandin D2 binds to PTGDR protein] CTD PMID:9579725 PMID:15528449 PMID:20719937 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases response to substance ISO BW 245C results in decreased susceptibility to TGFB1 protein CTD PMID:20719937 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      chemical role 19589
        donor 18895
          Bronsted acid 18783
            oxoacid 18744
              carbon oxoacid 18601
                carboxylic acid 18597
                  monocarboxylic acid 17843
                    7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid 2
                      (3R,4S)-BW 245C + 0
                      (3S,4R)-BW 245C + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic molecule 19856
                              organic cyclic compound 19612
                                organic heterocyclic compound 18824
                                  organic heteromonocyclic compound 17151
                                    diazolidine 998
                                      imidazolidines 989
                                        imidazolidinone 612
                                          imidazolidine-2,4-dione 477
                                            7-[3-(3-cyclohexyl-3-hydroxypropyl)-2,5-dioxoimidazolidin-4-yl]heptanoic acid 2
                                              (3R,4S)-BW 245C + 0
                                              (3S,4R)-BW 245C + 0
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