triazoloquinazoline - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	triazoloquinazoline	go back to main search page
Accession:	CHEBI:131355	browse the term
Definition:	An organic heterotricyclic compound that consists of a triazole ring ortho-fused at any position to a quinazoline ring system.
Synonyms:	related_synonym:	triazoloquinazolines

show annotations for term's descendants Sort by:
Rat (7) Mouse (7) Human (7) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (7)

CGS 15943

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

bone morphogenetic protein 6

multiple interactions

9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; 9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form]

NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365

G

bone morphogenetic protein receptor type 1B

increases expression

9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine results in increased expression of BMPR1B mRNA

NCBI chr 2:230,538,252...230,871,077
Ensembl chr 2:230,541,558...230,871,368

G

bone morphogenetic protein receptor type 2

increases expression

9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine results in increased expression of BMPR2 mRNA

NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809

G

furin (paired basic amino acid cleaving enzyme)

decreases expression

9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine results in decreased expression of FURIN mRNA

NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314

G

hepcidin antimicrobial peptide

decreases secretion
decreases expression
multiple interactions

9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine results in decreased secretion of HAMP protein modified form
9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine results in decreased expression of HAMP mRNA
9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine inhibits the reaction [BMP6 protein results in increased expression of HAMP mRNA]; 9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine inhibits the reaction [BMP6 protein results in increased secretion of HAMP protein modified form]

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

hemojuvelin BMP co-receptor

decreases expression

9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine results in decreased expression of HJV mRNA

NCBI chr 2:184,065,970...184,069,851
Ensembl chr 2:184,065,970...184,069,850

G

transferrin receptor 2

decreases expression

9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine results in decreased expression of TFR2 mRNA; 9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine results in decreased expression of TFR2 protein

NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19818
chemical entity	19816
atom	19816
nonmetal atom	19749
nitrogen atom	18922
nitrogen molecular entity	18922
organonitrogen compound	18757
organonitrogen heterocyclic compound	18027
triazoloquinazoline	7
CGS 15943	7
Path 2
Term	Annotations
CHEBI ontology	19818
subatomic particle	19816
composite particle	19816
hadron	19816
baryon	19816
nucleon	19816
atomic nucleus	19816
atom	19816
main group element atom	19761
p-block element atom	19761
carbon group element atom	19703
carbon atom	19698
organic molecular entity	19698
organic molecule	19656
organic cyclic compound	19461
organic heterocyclic compound	18817
organic heteropolycyclic compound	18297
organic heterotricyclic compound	15634
triazoloquinazoline	7
CGS 15943	7

paths to the root