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Accession:CHEBI:131196 term browser browse the term
Definition:A member of the class of pyrazoles that is N-[4-(pyrazol-1-yl)phenyl]glycinamide in which the pyrazole ring is substituted at positions 3 and 5 by trifluoromethyl and phenanthrene-2-yl groups respectively.
Synonyms:exact_synonym: N-{4-[5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl}glycinamide
 related_synonym: AR 12;   Formula=C26H19F3N4O;   InChI=1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34);   InChIKey=YULUCECVQOCQFQ-UHFFFAOYSA-N;   PDK1 inhibitor AR-12;   SMILES=C(=O)(NC1=CC=C(C=C1)N2N=C(C=C2C3=CC=4C(=C5C(=CC4)C=CC=C5)C=C3)C(F)(F)F)CN
 xref: CAS:742112-33-0
 xref_mesh: MESH:C500894
 xref: PMID:22354011;   PMID:23652278;   PMID:23706161;   PMID:25103559;   PMID:25267669;   PMID:25447826;   PMID:25482718;   PMID:25546329;   PMID:25689303;   PMID:25736380;   PMID:26419972;   PMID:26768723;   PMID:26787696;   PMID:26887051;   Reaxys:11001693;   Wikipedia:OSU-03012

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OSU-03012 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Pdpk1 3-phosphoinositide dependent protein kinase-1 JBrowse link 10 13,446,373 13,525,248 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    role 19727
      biological role 19726
        xenobiotic 18408
          phenanthrenes 105
            OSU-03012 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      carbon group element atom 19559
                        carbon atom 19548
                          organic molecular entity 19548
                            organic group 18463
                              organic divalent group 18456
                                organodiyl group 18456
                                  carbonyl group 18356
                                    carbonyl compound 18356
                                      carboxylic acid 18027
                                        amino acid 12478
                                          alpha-amino acid 7713
                                            L-alpha-amino acid 7384
                                              serine family amino acid 1794
                                                glycine 847
                                                  glycine derivative 835
                                                    OSU-03012 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.