Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:IP3 receptor antagonist
go back to main search page
Accession:CHEBI:131186 term browser browse the term
Definition:An antagonist that binds to and deactivates IP3 receptors.
Synonyms:related_synonym: D-myo-inositol 1,4,5-trisphosphate receptor antagonist;   D-myo-inositol 1,4,5-trisphosphate receptor antagonists;   IP3 antagonist;   IP3 antagonists;   IP3 receptor;   InsP3R antagonist;   InsP3R antagonists;   inositol trisphosphate receptor antagonist;   inositol trisphosphate receptor antagonists
 xref: Wikipedia:Inositol_trisphosphate_receptor



show annotations for term's descendants           Sort by:
 
2-aminoethoxydiphenylborane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP 2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased expression of BAX protein] CTD PMID:29883672 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP 2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in decreased expression of BCL2 protein] CTD PMID:29883672 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Casp12 caspase 12 multiple interactions EXP 2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased cleavage of CASP12 protein] CTD PMID:29883672 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
JBrowse link
G Casp3 caspase 3 multiple interactions EXP 2-aminoethoxydiphenylborane inhibits the reaction [cadmium acetate results in increased cleavage of CASP3 protein] CTD PMID:29883672 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Nitric Oxide]; 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Reactive Oxygen Species] CTD PMID:14607919 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Grm1 glutamate metabotropic receptor 1 multiple interactions EXP 2-aminoethoxydiphenylborane inhibits the reaction [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] CTD PMID:14622174 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO 2-aminoethoxydiphenylborane inhibits the reaction [bisphenol A results in increased expression of NFE2L2 protein] CTD PMID:33408296 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
xestospongin C term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions EXP xestospongin C inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Cd14 CD14 molecule increases expression ISO xestospongin C results in increased expression of CD14 protein CTD PMID:23395717 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP xestospongin C inhibits the reaction [Calcium results in decreased secretion of CYCS protein] CTD PMID:15345483 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Dnm1l dynamin 1-like multiple interactions ISO xestospongin C inhibits the reaction [Homocysteine results in increased expression of and results in increased phosphorylation of DNM1L protein] CTD PMID:33751715 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions ISO xestospongin C inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid] CTD PMID:19014389 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
JBrowse link
G Htt huntingtin multiple interactions ISO xestospongin C inhibits the reaction [Isoflurane promotes the reaction [HTT protein mutant form binds to HTT protein mutant form]] CTD PMID:21059370 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO xestospongin C results in increased expression of ITGAM protein CTD PMID:23395717 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO xestospongin C inhibits the reaction [Ethanol results in increased expression of and affects the localization of ITPR1 protein] CTD PMID:17241155 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 multiple interactions ISO xestospongin C inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] CTD PMID:15201137 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases expression ISO xestospongin C results in increased expression of MAPK1 protein modified form CTD PMID:23395717 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases expression ISO xestospongin C results in increased expression of MAPK3 protein modified form CTD PMID:23395717 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP xestospongin C inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] CTD PMID:16787574 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    role 20026
      biological role 20025
        pharmacological role 19122
          antagonist 16754
            IP3 receptor antagonist 19
              2-aminoethoxydiphenylborane 7
              xestospongin C 12
paths to the root