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Accession:CHEBI:1296 term browser browse the term
Definition:An oxysterol that is cholesterol substituted by a hydroxy group at position 20.
Synonyms:exact_synonym: cholest-5-ene-3beta,20-diol
 related_synonym: (20S)-20-Hydroxycholesterol;   (3beta)-cholest-5-ene-3,20-diol;   20(S)-OHC;   20(S)-hydroxycholesterol;   20alpha-Hydroxycholesterol;   Formula=C27H46O2;   InChI=1S/C27H46O2/c1-18(2)7-6-14-27(5,29)24-11-10-22-21-9-8-19-17-20(28)12-15-25(19,3)23(21)13-16-26(22,24)4/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t20-,21-,22-,23-,24-,25-,26-,27-/m0/s1;   InChIKey=MCKLJFJEQRYRQT-APGJSSKUSA-N;   SMILES=C1[C@@]2([C@]3(CC[C@]4([C@]([C@@]3(CC=C2C[C@H](C1)O)[H])(CC[C@@]4([C@](C)(CCCC(C)C)O)[H])[H])C)[H])C
 alt_id: CHEBI:43170
 xref: CAS:516-72-3 "ChemIDplus";   CAS:516-72-3 "KEGG COMPOUND";   DrugBank:DB04704;   HMDB:HMDB0006283;   KEGG:C05500;   LIPID_MAPS_instance:LMST01010201 "LIPID MAPS"
 xref_mesh: MESH:C025813
 xref: MetaCyc:2-HYDROXY-CHOLESTEROL;   PDBeChem:HC2;   PMID:1270422 "Europe PMC";   PMID:17200122 "Europe PMC";   PMID:17638575 "Europe PMC";   PMID:19839776 "Europe PMC";   PMID:20683129 "Europe PMC";   PMID:22231273 "Europe PMC";   PMID:23831757 "Europe PMC";   PMID:24596093 "Europe PMC";   PMID:25523141 "Europe PMC";   PMID:25765115 "Europe PMC";   PMID:26902390 "Europe PMC";   PMID:6042125 "Europe PMC";   Reaxys:2062337 "Reaxys"

show annotations for term's descendants       view all columns           Sort by:
20-hydroxycholesterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:6480464
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 JBrowse link X 21,696,796 21,699,241 RGD:6480464
G Mc2r melanocortin 2 receptor JBrowse link 18 64,166,959 64,178,729 RGD:6480464
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 JBrowse link 3 22,998,900 23,020,441 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    chemical entity 19677
      molecular entity 19674
        polyatomic entity 19591
          heteroatomic molecular entity 19514
            hydroxides 18973
              organic hydroxy compound 18516
                hydroxy steroid 12359
                  20-hydroxy steroid 45
                    20-hydroxycholesterol 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic molecule 19353
                              organic cyclic compound 19102
                                organic polycyclic compound 16031
                                  steroid 12770
                                    hydroxy steroid 12359
                                      3-hydroxy steroid 9985
                                        3beta-hydroxy steroid 1973
                                          3beta-hydroxy-Delta(5)-steroid 1833
                                            cholesterol 312
                                              oxysterol 91
                                                20-hydroxycholesterol 5
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.