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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:alpha-cyclopiazonic acids
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Accession:CHEBI:12336 term browser browse the term
Synonyms:related_synonym: Formula=C20H20N2O3;   alpha-Cyclopiazonsaeure;   alpha-Zyklopiazonsaeure

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(6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO cyclopiazonic acid inhibits the reaction [Demecolcine results in increased activity of CASP3 protein] CTD PMID:12530016 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO cyclopiazonic acid inhibits the reaction [F2RL1 protein results in increased transport of Chlorides] CTD PMID:11804840 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit affects response to substance EXP JUNB mRNA affects the susceptibility to cyclopiazonic acid CTD PMID:18716665 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756 		JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 increases cleavage ISO cyclopiazonic acid results in increased cleavage of SPTAN1 protein CTD PMID:21516125 NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260 		JBrowse link
G Star steroidogenic acute regulatory protein increases expression EXP cyclopiazonic acid results in increased expression of STAR protein CTD PMID:22001352 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847 		JBrowse link
G Tp73 tumor protein p73 increases degradation ISO cyclopiazonic acid results in increased degradation of TP73 protein modified form CTD PMID:21516125 NCBI chr 5:171,355,876...171,415,354
Ensembl chr 5:171,355,876...171,415,354 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19817
    role 19767
      biological role 19767
        poison 18111
          toxin 14327
            mycotoxin 12230
              cyclopiazonic acid 6
                alpha-cyclopiazonic acids 6
                  (6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one 6
                  alpha-cyclopiazonic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19817
    subatomic particle 19815
      composite particle 19815
        hadron 19815
          baryon 19815
            nucleon 19815
              atomic nucleus 19815
                atom 19815
                  main group element atom 19705
                    p-block element atom 19705
                      carbon group element atom 19614
                        carbon atom 19603
                          organic molecular entity 19603
                            organic molecule 19532
                              organic cyclic compound 19348
                                organic heterocyclic compound 18475
                                  organic heteropolycyclic compound 17874
                                    organic heterobicyclic compound 16794
                                      benzopyrrole 9549
                                        indoles 9220
                                          cyclopiazonic acid 6
                                            alpha-cyclopiazonic acids 6
                                              (6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one 6
                                              alpha-cyclopiazonic acid 0
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