Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2-methoxyestrone
go back to main search page
Accession:CHEBI:1189 term browser browse the term
Definition:A 17-oxo steroid that is estrone in which the hydrogen at position 2 has been replaced by a methoxy group.
Synonyms:exact_synonym: 3=hydroxy-2-methoxyestra-1,3,5(10)-trien-17-one
 related_synonym: Formula=C19H24O3;   InChI=1S/C19H24O3/c1-19-8-7-12-13(15(19)5-6-18(19)21)4-3-11-9-16(20)17(22-2)10-14(11)12/h9-10,12-13,15,20H,3-8H2,1-2H3/t12-,13+,15-,19-/m0/s1;   InChIKey=WHEUWNKSCXYKBU-QPWUGHHJSA-N;   SMILES=[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)c(OC)cc21
 xref: CAS:362-08-3;   KEGG:C05299;   LIPID_MAPS_instance:LMST02010033
 xref_mesh: MESH:C003655
 xref: PMID:14577664;   PMID:21488127



show annotations for term's descendants           Sort by:
 
2-methoxyestrone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions ISO [HSD17B2 protein results in increased metabolism of and results in decreased activity of 2-methoxyestradiol] which results in increased chemical synthesis of 2-methoxyestrone CTD PMID:16397246 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    role 19746
      application 19492
        pharmaceutical 19351
          drug 19351
            antineoplastic agent 17359
              estrone 129
                2-methoxyestrone 1
                  2-methoxyestrone 3-O-(beta-D-glucuronide) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            organic group 18713
                              organic divalent group 18697
                                organodiyl group 18697
                                  carbonyl group 18646
                                    carbonyl compound 18646
                                      ketone 16955
                                        oxo steroid 10281
                                          17-oxo steroid 262
                                            estrone 129
                                              2-methoxyestrone 1
                                                2-methoxyestrone 3-O-(beta-D-glucuronide) 0
paths to the root