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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:116278 term browser browse the term
Definition:A fluoroquinolone antibiotic, used (generally as the hydrochloride salt) to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery.
Synonyms:exact_synonym: 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
 related_synonym: 1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid;   Formula=C17H19F2N3O3;   InChI=1S/C17H19F2N3O3/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25);   InChIKey=ZEKZLJVOYLTDKK-UHFFFAOYSA-N;   LFLX;   Lomefloxacine;   Lomefloxacino;   Lomefloxacinum;   SMILES=CCn1cc(C(O)=O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12
 alt_id: CHEBI:6517
 xref: Beilstein:4210041;   CAS:98079-51-7;   DrugBank:DB00978;   Drug_Central:1594;   KEGG:C07078;   KEGG:D02318;   LINCS:LSM-5145
 xref_mesh: MESH:C053091
 xref: PMID:11195849;   PMID:3134843;   PMID:3348607;   PMID:3476021;   Patent:DE3433924;   Patent:US4528287;   Wikipedia:Lomefloxacin

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lomefloxacin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects binding ISO lomefloxacin binds to KCNH2 protein CTD PMID:34058295 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19751
    role 19724
      biological role 19722
        antimicrobial agent 17897
          lomefloxacin 1
            lomefloxacin hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19751
    subatomic particle 19749
      composite particle 19749
        hadron 19749
          baryon 19749
            nucleon 19749
              atomic nucleus 19749
                atom 19749
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19644
                        carbon atom 19640
                          organic molecular entity 19640
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18799
                                    carbonyl compound 18799
                                      carboxylic acid 18515
                                        aromatic carboxylic acid 11797
                                          quinolinemonocarboxylic acid 103
                                            lomefloxacin 1
                                              lomefloxacin hydrochloride 0
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